| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
121 genes differentially expressed following the Voriconazole_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.301196 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.191504 |
| DSCAM | Down syndrome cell adhesion molecule | 0.132696 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.126971 |
| VMP1 | vacuole membrane protein 1 | 0.121668 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.108163 |
| FLNB | filamin B, beta | 0.107453 |
| MEIS2 | Meis homeobox 2 | 0.107154 |
| GOLGA4 | golgin A4 | 0.10542 |
| RUNX1 | runt-related transcription factor 1 | 0.104139 |
| ZNF292 | zinc finger protein 292 | 0.100292 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0981595 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0931069 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0867116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0865655 |
| PKM | pyruvate kinase, muscle | 0.0863346 |
| EGFR | epidermal growth factor receptor | 0.0860041 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0848575 |
| SETD5 | SET domain containing 5 | 0.0842078 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0839607 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0803251 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0785274 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0767919 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0742801 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0724251 |
| RPS3 | ribosomal protein S3 | 0.069175 |
| RPL23 | ribosomal protein L23 | 0.0666931 |
| ANXA2 | annexin A2 | 0.0629899 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0617076 |
| RPS6 | ribosomal protein S6 | 0.0607005 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0566231 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0528988 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0518502 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0517605 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.051617 |
| PDE10A | phosphodiesterase 10A | 0.0504137 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0500438 |
| RPL34 | ribosomal protein L34 | 0.0474114 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0473756 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0465886 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0434529 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0430804 |
| RBM39 | RNA binding motif protein 39 | 0.0420488 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0361738 |
| CANX | calnexin | 0.0343797 |
| EZR | ezrin | 0.0313569 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0308976 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0292432 |
| ENO1 | enolase 1, (alpha) | 0.0285095 |
| PTMA | prothymosin, alpha | 0.0271333 |
| PRKCA | protein kinase C, alpha | 0.0260583 |
| ASPH | aspartate beta-hydroxylase | 0.0257371 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0191199 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0190897 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0179106 |
| MED13L | mediator complex subunit 13-like | 0.0176949 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0157663 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0146903 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00658443 |
| DST | dystonin | 0.00641424 |
| WDR43 | WD repeat domain 43 | 0.00500289 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.00487571 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00367328 |
| RPL35A | ribosomal protein L35a | 0.0029486 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.00159587 |
| ACTG1 | actin gamma 1 | 5.70701E-5 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.185746 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.17028 |
| VIM | vimentin | -0.13885 |
| TMSB10 | thymosin beta 10 | -0.135654 |
| SNX9 | sorting nexin 9 | -0.125514 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.120491 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.112713 |
| NAV2 | neuron navigator 2 | -0.0887282 |
| FN1 | fibronectin 1 | -0.081804 |
| RPS16 | ribosomal protein S16 | -0.0758755 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0681758 |
| LAMB3 | laminin, beta 3 | -0.0636936 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0632571 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0624011 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0595466 |
| ITGA6 | integrin, alpha 6 | -0.0585881 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0569223 |
| RPS8 | ribosomal protein S8 | -0.0558218 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0534837 |
| LMO7 | LIM domain 7 | -0.0524633 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0509433 |
| MYOF | myoferlin | -0.0504572 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0499513 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0486261 |
| CDH13 | cadherin 13 | -0.0477299 |
| STAG2 | stromal antigen 2 | -0.0475194 |
| INHBA | inhibin, beta A | -0.0439312 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0438915 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0433969 |
| NDRG1 | N-myc downstream regulated 1 | -0.0430174 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0423486 |
| JMJD1C | jumonji domain containing 1C | -0.0421225 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0389853 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0370013 |
| CD44 | CD44 molecule (Indian blood group) | -0.0349868 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340918 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0301339 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0298769 |
| RBM25 | RNA binding motif protein 25 | -0.0294832 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0246876 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0240808 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0225005 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0218852 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0214498 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0209733 |
| RPLP2 | ribosomal protein, large, P2 | -0.0207891 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0179247 |
| PGK1 | phosphoglycerate kinase 1 | -0.0173116 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0148821 |
| WASF2 | WAS protein family, member 2 | -0.0138561 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00941174 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.00892273 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00706288 |
| EFNA5 | ephrin-A5 | -0.0065246 |
| RPL26 | ribosomal protein L26 | -0.00293853 |
