| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.141318 |
| ENAH | enabled homolog (Drosophila) | 0.118364 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.108281 |
| ZNF292 | zinc finger protein 292 | 0.104528 |
| TSC22D2 | TSC22 domain family, member 2 | 0.102883 |
| PEG10 | paternally expressed 10 | 0.0821322 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0726961 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0660214 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0657453 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.063613 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0614957 |
| PRTG | protogenin | 0.0608449 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0603309 |
| MTF2 | metal response element binding transcription factor 2 | 0.0601121 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0545151 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0533969 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0526233 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0523747 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0507053 |
| POTEF | POTE ankyrin domain family, member F | 0.0505563 |
| ANXA1 | annexin A1 | 0.0492879 |
| STAG2 | stromal antigen 2 | 0.047889 |
| USP3 | ubiquitin specific peptidase 3 | 0.0459751 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0452504 |
| CALR | calreticulin | 0.0447976 |
| USP25 | ubiquitin specific peptidase 25 | 0.0440379 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0440378 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0438227 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0437547 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0435573 |
| NCKAP1 | NCK-associated protein 1 | 0.0426289 |
| TPM3 | tropomyosin 3 | 0.0424988 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0423185 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0407609 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0402378 |
| MED13L | mediator complex subunit 13-like | 0.0397665 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0397635 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0393289 |
| WDR43 | WD repeat domain 43 | 0.0390902 |
| RBM20 | RNA binding motif protein 20 | 0.0390351 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0389866 |
| H2AZ2 | H2A.Z variant histone 2 | 0.0387294 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0385857 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0385204 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0383741 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0380267 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0379588 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0377612 |
| POU2F1 | POU class 2 homeobox 1 | 0.037444 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0371265 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0371007 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0370073 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0368074 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0367455 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0345089 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0344456 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0343201 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0341347 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0337816 |
| ACTN4 | actinin, alpha 4 | 0.0337053 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0332975 |
| SNX3 | sorting nexin 3 | 0.0332551 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0331311 |
| PHIP | pleckstrin homology domain interacting protein | 0.0327702 |
| ZNF608 | zinc finger protein 608 | 0.0327386 |
| RPL7 | ribosomal protein L7 | 0.0325037 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0323459 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0318971 |
| CDC73 | cell division cycle 73 | 0.0318971 |
| XPO1 | exportin 1 | 0.0318707 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0316499 |
| SRP54 | signal recognition particle 54kDa | 0.0315481 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.031191 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0311703 |
| KIF1B | kinesin family member 1B | 0.0307916 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0305592 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0305457 |
| CLTC | clathrin, heavy chain (Hc) | 0.0302322 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0302159 |
| ITGAV | integrin, alpha V | 0.029884 |
| CCN2 | cellular communication network factor 2 | 0.0297687 |
| MB21D2 | Mab-21 domain containing 2 | 0.0297639 |
| NTM | neurotrimin | 0.0295207 |
| NUP153 | nucleoporin 153kDa | 0.029367 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0292726 |
| SLK | STE20-like kinase | 0.0285813 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0283863 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0282553 |
| RHEB | Ras homolog enriched in brain | 0.0282231 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0281022 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0280967 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0279664 |
| QKI | QKI, KH domain containing, RNA binding | 0.0277179 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0275787 |
| SRPK2 | SRSF protein kinase 2 | 0.0274597 |
| DST | dystonin | 0.0273721 |
| GSPT1 | G1 to S phase transition 1 | 0.0269054 |
| RPL3 | ribosomal protein L3 | 0.0266883 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0266414 |
| RPS12 | ribosomal protein S12 | 0.0265388 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.120248 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.110187 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1065 |
| AHNAK | AHNAK nucleoprotein | -0.0877655 |
| TMSB10 | thymosin beta 10 | -0.0823733 |
| PCDH9 | protocadherin 9 | -0.0782405 |
| PTMA | prothymosin, alpha | -0.0773811 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.073266 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0727858 |
| H1-0 | H1.0 linker histone | -0.0719615 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0713302 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0632871 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0552566 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0541838 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0467012 |
| HMGB1 | high mobility group box 1 | -0.0465529 |
| RSF1 | remodeling and spacing factor 1 | -0.0450465 |
| GPC3 | glypican 3 | -0.0442307 |
| BBX | bobby sox homolog (Drosophila) | -0.0436889 |
| RPL19 | ribosomal protein L19 | -0.042009 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0404037 |
| RPS16 | ribosomal protein S16 | -0.0397578 |
| VIM | vimentin | -0.0394272 |
| SGO2 | shugoshin 2 | -0.039395 |
| RPL31 | ribosomal protein L31 | -0.0392747 |
| PRELID2 | PRELI domain containing 2 | -0.0389481 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.038153 |
| TEX11 | testis expressed 11 | -0.0375809 |
| CENPF | centromere protein F, 350/400kDa | -0.0374931 |
| RPLP1 | ribosomal protein, large, P1 | -0.0369158 |
| MKI67 | marker of proliferation Ki-67 | -0.0366955 |
| RPL23 | ribosomal protein L23 | -0.0360617 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0359849 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0359508 |
| RAD51B | RAD51 paralog B | -0.0359322 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0357914 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.035787 |
| RPL34 | ribosomal protein L34 | -0.0356208 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0355308 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0352872 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0346679 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0333595 |
| EMP1 | epithelial membrane protein 1 | -0.0331271 |
| RPS8 | ribosomal protein S8 | -0.0326357 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0317721 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0314636 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0312154 |
| NDRG1 | N-myc downstream regulated 1 | -0.0308215 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.030536 |
| CENPE | centromere protein E, 312kDa | -0.0303833 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0300429 |
| AK1 | adenylate kinase 1 | -0.0299246 |
| CBX3 | chromobox homolog 3 | -0.0289903 |
| METAP2 | methionyl aminopeptidase 2 | -0.0287421 |
| RPL11 | ribosomal protein L11 | -0.0285737 |
| TMSB4X | thymosin beta 4, X-linked | -0.0281906 |
| TUBB | tubulin, beta class I | -0.0279866 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0278774 |
| ASPH | aspartate beta-hydroxylase | -0.0278173 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0277383 |
| MORF4L2 | mortality factor 4 like 2 | -0.0276641 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0275558 |
| MEIS2 | Meis homeobox 2 | -0.0274048 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0265598 |
| SMYD3 | SET and MYND domain containing 3 | -0.0264148 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0262808 |
| PCDH7 | protocadherin 7 | -0.0262466 |
| DEK | DEK proto-oncogene | -0.0261728 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0258405 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0256416 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0255805 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.02548 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0254354 |
| RPL35A | ribosomal protein L35a | -0.0251683 |
| BRDT | bromodomain, testis-specific | -0.0251448 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0249022 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0248594 |
| CUX1 | cut-like homeobox 1 | -0.0248243 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0248172 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0248151 |
| FN1 | fibronectin 1 | -0.0244274 |
| BPTF | bromodomain PHD finger transcription factor | -0.0243569 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0243358 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0238031 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0237346 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0236918 |
| S100A10 | S100 calcium binding protein A10 | -0.0235322 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0231448 |
| RPL26 | ribosomal protein L26 | -0.022996 |
| FTL | ferritin, light polypeptide | -0.0228167 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0226345 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0225983 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0225958 |
| RTN4 | reticulon 4 | -0.0223644 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0221635 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0221366 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0220548 |
| DSPP | dentin sialophosphoprotein | -0.022028 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0218746 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0218144 |
