| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.125333 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0959793 |
| EGFR | epidermal growth factor receptor | 0.0732599 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0579235 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0479795 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0478974 |
| TXNRD1 | thioredoxin reductase 1 | 0.0460874 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0440764 |
| POTEF | POTE ankyrin domain family, member F | 0.0432477 |
| VCL | vinculin | 0.0430289 |
| PRELID2 | PRELI domain containing 2 | 0.0426298 |
| SLC38A2 | solute carrier family 38, member 2 | 0.041195 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0411164 |
| ANK2 | ankyrin 2, neuronal | 0.037312 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0367306 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0360624 |
| EVI5 | ecotropic viral integration site 5 | 0.0359686 |
| PDGFC | platelet derived growth factor C | 0.035914 |
| ZNF608 | zinc finger protein 608 | 0.0352498 |
| FNIP1 | folliculin interacting protein 1 | 0.0335299 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0331606 |
| PYGB | phosphorylase, glycogen; brain | 0.0331195 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0324602 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.031505 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0312827 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0312814 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0312383 |
| PKM | pyruvate kinase, muscle | 0.0311314 |
| METTL15 | methyltransferase like 15 | 0.0308787 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.030771 |
| TJP1 | tight junction protein 1 | 0.0305873 |
| RBM26 | RNA binding motif protein 26 | 0.0302998 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0298842 |
| TMEM65 | transmembrane protein 65 | 0.029741 |
| SQSTM1 | sequestosome 1 | 0.028919 |
| GOLGA4 | golgin A4 | 0.0286807 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0285699 |
| SBF2 | SET binding factor 2 | 0.0279562 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0271774 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0263234 |
| HM13 | histocompatibility (minor) 13 | 0.025547 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0254991 |
| SMYD3 | SET and MYND domain containing 3 | 0.0254261 |
| VIM | vimentin | 0.0251686 |
| ASPH | aspartate beta-hydroxylase | 0.0250982 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0250557 |
| ENO1 | enolase 1, (alpha) | 0.0247729 |
| NUP58 | nucleoporin 58 | 0.0247285 |
| TMSB10 | thymosin beta 10 | 0.0247174 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.024705 |
| DENND4A | DENN/MADD domain containing 4A | 0.0244297 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0240138 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0239788 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.023798 |
| JMJD1C | jumonji domain containing 1C | 0.0237129 |
| VMP1 | vacuole membrane protein 1 | 0.022936 |
| COG6 | component of oligomeric golgi complex 6 | 0.0227813 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0226898 |
| USP34 | ubiquitin specific peptidase 34 | 0.0225571 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0223202 |
| LDHA | lactate dehydrogenase A | 0.0222655 |
| MEF2A | myocyte enhancer factor 2A | 0.0222376 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0218772 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0212045 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0211967 |
| PLK2 | polo-like kinase 2 | 0.0210267 |
| PTEN | phosphatase and tensin homolog | 0.0209096 |
| CLTC | clathrin, heavy chain (Hc) | 0.0206991 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0206504 |
| CCNL1 | cyclin L1 | 0.0205156 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0204539 |
| PCBP2 | poly(rC) binding protein 2 | 0.0204029 |
| FHIT | fragile histidine triad | 0.0203049 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201549 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.020058 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0200264 |
| PMM2 | phosphomannomutase 2 | 0.0199483 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0198774 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0197279 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0195154 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0194114 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0192177 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0191897 |
| PRDX2 | peroxiredoxin 2 | 0.0190914 |
| PTK2 | protein tyrosine kinase 2 | 0.0190453 |
| RFX7 | regulatory factor X, 7 | 0.019042 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.019019 |
| EFNA5 | ephrin-A5 | 0.0189668 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0189521 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0188892 |
| RBM39 | RNA binding motif protein 39 | 0.0188847 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0188593 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0184368 |
| BRD2 | bromodomain containing 2 | 0.0183794 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0181065 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0177226 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0176708 |
| ZNF217 | zinc finger protein 217 | 0.0174006 |
| MED13 | mediator complex subunit 13 | 0.0173934 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0171802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.245424 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0883786 |
| AHNAK | AHNAK nucleoprotein | -0.0636844 |
| BMP10 | bone morphogenetic protein 10 | -0.0625554 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0510367 |
| TMSB4X | thymosin beta 4, X-linked | -0.0474426 |
| NAV2 | neuron navigator 2 | -0.0467714 |
| MKI67 | marker of proliferation Ki-67 | -0.0439309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0416585 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0396133 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0391391 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0389058 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0369706 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.035916 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0333425 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0323832 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0321284 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0320395 |
| CENPF | centromere protein F, 350/400kDa | -0.0316201 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0308698 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0303999 |
| RPL26 | ribosomal protein L26 | -0.0288986 |
| RPLP1 | ribosomal protein, large, P1 | -0.0283042 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.028286 |
| RPL35A | ribosomal protein L35a | -0.0279678 |
| ANXA1 | annexin A1 | -0.0274915 |
| FOXP1 | forkhead box P1 | -0.0266317 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0263929 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0258436 |
| RPL34 | ribosomal protein L34 | -0.0258066 |
| BCOR | BCL6 corepressor | -0.0257619 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0256039 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0243685 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.023813 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0237764 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0237052 |
| RPS24 | ribosomal protein S24 | -0.0235412 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0235328 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0234234 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0233247 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0218746 |
| NFIA | nuclear factor I/A | -0.0215286 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0213246 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0210789 |
| USP3 | ubiquitin specific peptidase 3 | -0.0210111 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.020938 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0206165 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0201791 |
| S100A4 | S100 calcium binding protein A4 | -0.0199724 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.01992 |
| RPS8 | ribosomal protein S8 | -0.0199142 |
| MYOF | myoferlin | -0.0184713 |
| HMGB1 | high mobility group box 1 | -0.0179833 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0177862 |
| RPL38 | ribosomal protein L38 | -0.0175949 |
| RRM2 | ribonucleotide reductase M2 | -0.0175626 |
| KIF5B | kinesin family member 5B | -0.0173063 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0171954 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0170157 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0169472 |
| RPLP0 | ribosomal protein, large, P0 | -0.0168811 |
| GSE1 | Gse1 coiled-coil protein | -0.0168029 |
| ANLN | anillin, actin binding protein | -0.0164567 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0161505 |
| S100A6 | S100 calcium binding protein A6 | -0.0161098 |
| OGA | O-GlcNAcase | -0.016064 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0160354 |
| FAM13A | family with sequence similarity 13, member A | -0.0159977 |
| ZNF438 | zinc finger protein 438 | -0.0157628 |
| PDE7B | phosphodiesterase 7B | -0.0154347 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0152704 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0149454 |
| RPL23 | ribosomal protein L23 | -0.0147887 |
| MYO5C | myosin VC | -0.0147527 |
| RPL4 | ribosomal protein L4 | -0.0147178 |
| RRBP1 | ribosome binding protein 1 | -0.0145425 |
| RPL37A | ribosomal protein L37a | -0.0145151 |
| RPL19 | ribosomal protein L19 | -0.01451 |
| DENND1A | DENN/MADD domain containing 1A | -0.0144274 |
| S100A10 | S100 calcium binding protein A10 | -0.0143981 |
| GLI2 | GLI family zinc finger 2 | -0.0143553 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0143134 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0142228 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0141753 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0141119 |
| FAM162A | family with sequence similarity 162, member A | -0.0141099 |
| PUM2 | pumilio RNA-binding family member 2 | -0.014057 |
| RPS6 | ribosomal protein S6 | -0.014042 |
| RPL13A | ribosomal protein L13a | -0.0139555 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0139053 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0138112 |
| XPO1 | exportin 1 | -0.0137826 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0137823 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0136105 |
| YBX3 | Y box binding protein 3 | -0.0134796 |
| GNAS | GNAS complex locus | -0.0134589 |
| KIF18B | kinesin family member 18B | -0.0134452 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0134292 |
| NOP56 | NOP56 ribonucleoprotein | -0.0134279 |
| LMNA | lamin A/C | -0.013377 |