| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.171776 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.133388 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.122484 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.120628 |
| COL6A3 | collagen, type VI, alpha 3 | 0.120516 |
| CD44 | CD44 molecule (Indian blood group) | 0.119421 |
| PDE10A | phosphodiesterase 10A | 0.112199 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.111277 |
| NDRG1 | N-myc downstream regulated 1 | 0.105024 |
| FNDC3B | fibronectin type III domain containing 3B | 0.104496 |
| VCAN | versican | 0.101344 |
| FRMD4A | FERM domain containing 4A | 0.0995899 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0975896 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0955037 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0930223 |
| LDHA | lactate dehydrogenase A | 0.0873813 |
| VEGFA | vascular endothelial growth factor A | 0.0864155 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0813698 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0806627 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0788905 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0762624 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0722301 |
| HDAC9 | histone deacetylase 9 | 0.0692305 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0645305 |
| DST | dystonin | 0.0639863 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0613803 |
| NAV2 | neuron navigator 2 | 0.0610107 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0602754 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0591102 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0583678 |
| ATXN1 | ataxin 1 | 0.0574465 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0547941 |
| MYOF | myoferlin | 0.0544792 |
| HMGA2 | high mobility group AT-hook 2 | 0.0527576 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0521535 |
| FNIP1 | folliculin interacting protein 1 | 0.0514707 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.051102 |
| CADM1 | cell adhesion molecule 1 | 0.0497184 |
| FLNB | filamin B, beta | 0.049691 |
| TNS3 | tensin 3 | 0.049243 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0485329 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0478214 |
| MSN | moesin | 0.0474966 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0471518 |
| ENO1 | enolase 1, (alpha) | 0.0462974 |
| VIM | vimentin | 0.0458087 |
| SMAD3 | SMAD family member 3 | 0.0453141 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0451961 |
| MMP12 | matrix metallopeptidase 12 | 0.045153 |
| ASPH | aspartate beta-hydroxylase | 0.0440281 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0437128 |
| SFTPA2 | surfactant protein A2 | 0.0421019 |
| ARRDC3 | arrestin domain containing 3 | 0.0416063 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0415951 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0414967 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0414467 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0414306 |
| CDK19 | cyclin-dependent kinase 19 | 0.0414071 |
| LOXL2 | lysyl oxidase-like 2 | 0.0409586 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0407686 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0404434 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0404061 |
| CDH13 | cadherin 13 | 0.0396546 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0394166 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0393694 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0386094 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0385125 |
| HLA-A | major histocompatibility complex, class I, A | 0.0383623 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0378087 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0377936 |
| COL5A1 | collagen, type V, alpha 1 | 0.0377268 |
| ARFGEF3 | ARFGEF family member 3 | 0.0373653 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0373012 |
| B2M | beta-2-microglobulin | 0.0369904 |
| RND3 | Rho family GTPase 3 | 0.0364602 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0359865 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0359162 |
| EGFR | epidermal growth factor receptor | 0.0355972 |
| STC1 | stanniocalcin 1 | 0.0355099 |
| STC2 | stanniocalcin 2 | 0.0354555 |
| FMNL2 | formin-like 2 | 0.0347419 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0345034 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0341565 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0340894 |
| SEPTIN9 | septin 9 | 0.0339793 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0339337 |
| PCBP3 | poly(rC) binding protein 3 | 0.0335685 |
| COL1A2 | collagen, type I, alpha 2 | 0.0334414 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0330225 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0329137 |
| DIAPH2 | diaphanous-related formin 2 | 0.0326309 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0325184 |
| CALR | calreticulin | 0.0314543 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0312445 |
| CDCP1 | CUB domain containing protein 1 | 0.0312104 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0310838 |
| LOX | lysyl oxidase | 0.0308569 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0301976 |
| GOLGB1 | golgin B1 | 0.0301248 |
| FAM219A | family with sequence similarity 219, member A | 0.0291096 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.0797181 |
| IER3 | immediate early response 3 | -0.0635718 |
| RPS6 | ribosomal protein S6 | -0.0513311 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0500656 |
| BICC1 | BicC family RNA binding protein 1 | -0.0496205 |
| RPS24 | ribosomal protein S24 | -0.0459819 |
| TMSB10 | thymosin beta 10 | -0.0427305 |
| PTMA | prothymosin, alpha | -0.036344 |
| RPL23 | ribosomal protein L23 | -0.0363178 |
| AHNAK | AHNAK nucleoprotein | -0.035113 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0336426 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0325453 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.032108 |
| RPL19 | ribosomal protein L19 | -0.0309495 |
| RPLP2 | ribosomal protein, large, P2 | -0.0304551 |
| RPLP1 | ribosomal protein, large, P1 | -0.030034 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0292216 |
| OGA | O-GlcNAcase | -0.0275249 |
| RPLP0 | ribosomal protein, large, P0 | -0.027433 |
| RPS8 | ribosomal protein S8 | -0.0273059 |
| DEK | DEK proto-oncogene | -0.0253871 |
| TUBB | tubulin, beta class I | -0.0248899 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0248392 |
| RPL12 | ribosomal protein L12 | -0.0242911 |
| RPL36 | ribosomal protein L36 | -0.0241581 |
| RPL37A | ribosomal protein L37a | -0.0239544 |
| HLA-B | major histocompatibility complex, class I, B | -0.0239491 |
| RPL36A | ribosomal protein L36a | -0.0228787 |
| FTL | ferritin, light polypeptide | -0.0228053 |
| WTAP | Wilms tumor 1 associated protein | -0.0227404 |
| TMSB4X | thymosin beta 4, X-linked | -0.0226083 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0223207 |
| ANXA2 | annexin A2 | -0.0222267 |
| RPS21 | ribosomal protein S21 | -0.0218481 |
| GNAS | GNAS complex locus | -0.0217861 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0213027 |
| RPL34 | ribosomal protein L34 | -0.0212231 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0210007 |
| RPL31 | ribosomal protein L31 | -0.0207992 |
| RPL35A | ribosomal protein L35a | -0.0203779 |
| RPL32 | ribosomal protein L32 | -0.0200383 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0197667 |
| SRGN | serglycin | -0.019559 |
| KLF6 | Kruppel-like factor 6 | -0.0193901 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0193631 |
| HMGB2 | high mobility group box 2 | -0.0191211 |
| RPL26 | ribosomal protein L26 | -0.0190394 |
| RPL9 | ribosomal protein L9 | -0.0188907 |
| TMEM123 | transmembrane protein 123 | -0.0186523 |
| FUS | FUS RNA binding protein | -0.0184255 |
| ANLN | anillin, actin binding protein | -0.0184108 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0183821 |
| TMEM263 | transmembrane protein 263 | -0.0183485 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0182745 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0175248 |
| NCOA7 | nuclear receptor coactivator 7 | -0.017379 |
| TFG | TRK-fused gene | -0.0172166 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0171843 |
| H1-0 | H1.0 linker histone | -0.0169276 |
| MT2A | metallothionein 2A | -0.0168732 |
| XAF1 | XIAP associated factor 1 | -0.0165639 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0164752 |
| H3-3B | H3.3 histone B | -0.0163633 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0160303 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0160147 |
| RPL11 | ribosomal protein L11 | -0.0157867 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0156951 |
| FAM162A | family with sequence similarity 162, member A | -0.0156459 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0153226 |
| RPS15 | ribosomal protein S15 | -0.015287 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0150556 |
| KIF4A | kinesin family member 4A | -0.0149394 |
| RPL35 | ribosomal protein L35 | -0.0146224 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0146149 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0145299 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0145296 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0145079 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0143146 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0142766 |
| RPL14 | ribosomal protein L14 | -0.0140828 |
| RPL38 | ribosomal protein L38 | -0.0139643 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0138706 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0138614 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | -0.0138403 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0138391 |
| RPS5 | ribosomal protein S5 | -0.013764 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0136115 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0135571 |
| ACTG1 | actin gamma 1 | -0.0135363 |
| RPS4X | ribosomal protein S4, X-linked | -0.0134583 |
| CD70 | CD70 molecule | -0.0133773 |
| RPL6 | ribosomal protein L6 | -0.0133187 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.013213 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0131555 |
| RPS19 | ribosomal protein S19 | -0.0131492 |
| RPS25 | ribosomal protein S25 | -0.0130751 |
| RBM39 | RNA binding motif protein 39 | -0.0130322 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0130104 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0128984 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0128248 |
