| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.13847 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0783762 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0757326 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0688122 |
| ANLN | anillin, actin binding protein | 0.0561816 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0527009 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.047409 |
| CDH13 | cadherin 13 | 0.0449395 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0424742 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0421644 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0421564 |
| NRXN3 | neurexin 3 | 0.0411317 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0395424 |
| XPO1 | exportin 1 | 0.038722 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0370865 |
| COG5 | component of oligomeric golgi complex 5 | 0.0363554 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0357361 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0343897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0343256 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0340797 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.033094 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0327949 |
| COPA | coatomer protein complex, subunit alpha | 0.0321449 |
| EFNA5 | ephrin-A5 | 0.0321034 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0319062 |
| LOXL2 | lysyl oxidase-like 2 | 0.03187 |
| GPSM2 | G-protein signaling modulator 2 | 0.0318272 |
| NDRG1 | N-myc downstream regulated 1 | 0.0315301 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0308995 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0307858 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0302284 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0293937 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0282528 |
| RRM2 | ribonucleotide reductase M2 | 0.0280343 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0278842 |
| PAPOLA | poly(A) polymerase alpha | 0.0275763 |
| LMO7 | LIM domain 7 | 0.0269696 |
| STC1 | stanniocalcin 1 | 0.0269651 |
| TTK | TTK protein kinase | 0.0266076 |
| FAM13B | family with sequence similarity 13, member B | 0.026286 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0262798 |
| FNIP1 | folliculin interacting protein 1 | 0.0261717 |
| RPL7 | ribosomal protein L7 | 0.0257721 |
| MKI67 | marker of proliferation Ki-67 | 0.0254447 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0252743 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0251346 |
| SEC24A | SEC24 family member A | 0.0251267 |
| PDE10A | phosphodiesterase 10A | 0.0249297 |
| PRKCA | protein kinase C, alpha | 0.024408 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.024252 |
| COL5A1 | collagen, type V, alpha 1 | 0.0237875 |
| MYOF | myoferlin | 0.0235313 |
| FAM168A | family with sequence similarity 168, member A | 0.0232388 |
| EGR1 | early growth response 1 | 0.0230009 |
| SNX3 | sorting nexin 3 | 0.0229139 |
| TMF1 | TATA element modulatory factor 1 | 0.0227567 |
| ARRDC3 | arrestin domain containing 3 | 0.0224145 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0222717 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0219381 |
| INSIG2 | insulin induced gene 2 | 0.0215717 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.0215709 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0215399 |
| DIAPH3 | diaphanous-related formin 3 | 0.0215029 |
| NOTCH2 | notch 2 | 0.0214901 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0212566 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0212074 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.0211929 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0211403 |
| RNF24 | ring finger protein 24 | 0.0211118 |
| ECT2 | epithelial cell transforming 2 | 0.0210649 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0210452 |
| RPL34 | ribosomal protein L34 | 0.0210118 |
| SRGN | serglycin | 0.0209182 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0209036 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0208655 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0207544 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0207301 |
| KIF18A | kinesin family member 18A | 0.0202809 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0201656 |
| TMEM167A | transmembrane protein 167A | 0.0199568 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0199142 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0198637 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0197671 |
| RNF145 | ring finger protein 145 | 0.0197387 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0197073 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0195069 |
| EMP3 | epithelial membrane protein 3 | 0.0195023 |
| IKBIP | IKBKB interacting protein | 0.0194989 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0194687 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0194624 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0194304 |
| MAP1B | microtubule-associated protein 1B | 0.019356 |
| SNX13 | sorting nexin 13 | 0.0193553 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0192881 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0192719 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0191494 |
| NUP153 | nucleoporin 153kDa | 0.0191484 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0191196 |
| YME1L1 | YME1-like 1 ATPase | 0.0189656 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0189398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.103592 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0994595 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0977502 |
| ENO1 | enolase 1, (alpha) | -0.0809657 |
| HLA-B | major histocompatibility complex, class I, B | -0.078329 |
| SDC4 | syndecan 4 | -0.0727752 |
| UBC | ubiquitin C | -0.0658104 |
| VIM | vimentin | -0.0638657 |
| SPAG9 | sperm associated antigen 9 | -0.0593116 |
| AHNAK | AHNAK nucleoprotein | -0.0529661 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0516425 |
| COL1A1 | collagen, type I, alpha 1 | -0.0468613 |
| SMAD3 | SMAD family member 3 | -0.0439533 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0431767 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0425319 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0407954 |
| WTAP | Wilms tumor 1 associated protein | -0.0396289 |
| SRPK2 | SRSF protein kinase 2 | -0.0392223 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0378327 |
| ANXA5 | annexin A5 | -0.0375829 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0361855 |
| H3-3B | H3.3 histone B | -0.0358872 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0349472 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0345322 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0343429 |
| JUN | jun proto-oncogene | -0.0342906 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0338433 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0336798 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0329599 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0322866 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0322787 |
| FLNA | filamin A, alpha | -0.0316338 |
| CDK6 | cyclin-dependent kinase 6 | -0.0314816 |
| CALD1 | caldesmon 1 | -0.030877 |
| GLIS3 | GLIS family zinc finger 3 | -0.0308411 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.030717 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0300798 |
| SEPTIN7 | septin 7 | -0.0297602 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0294931 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.029456 |
| MT2A | metallothionein 2A | -0.0293569 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0292412 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0291036 |
| RPLP1 | ribosomal protein, large, P1 | -0.0290764 |
| LDHA | lactate dehydrogenase A | -0.0288784 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0287208 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0284599 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0282598 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0281578 |
| TXNIP | thioredoxin interacting protein | -0.0280779 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0278545 |
| RTN4 | reticulon 4 | -0.0277822 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277578 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0276435 |
| QKI | QKI, KH domain containing, RNA binding | -0.0274222 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0272379 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0272347 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0271126 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0271024 |
| IL6 | interleukin 6 | -0.0270738 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0269678 |
| ANXA2 | annexin A2 | -0.0262155 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0259276 |
| RRBP1 | ribosome binding protein 1 | -0.0258008 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0257301 |
| FLNB | filamin B, beta | -0.0254832 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0254563 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0245357 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0245181 |
| PTMA | prothymosin, alpha | -0.024507 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0244597 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.024429 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0244274 |
| TPM3 | tropomyosin 3 | -0.0244198 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0242453 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0242054 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0241436 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0240768 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0240253 |
| RBM5 | RNA binding motif protein 5 | -0.0237827 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0237248 |
| RPS6 | ribosomal protein S6 | -0.023593 |
| HDLBP | high density lipoprotein binding protein | -0.0235008 |
| CD44 | CD44 molecule (Indian blood group) | -0.0233525 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0233241 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | -0.0232396 |
| GANAB | glucosidase, alpha; neutral AB | -0.0232089 |
| DIAPH1 | diaphanous-related formin 1 | -0.0231541 |
| AFAP1 | actin filament associated protein 1 | -0.0230628 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.022982 |
| TRIM56 | tripartite motif containing 56 | -0.0229509 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0222706 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.02227 |
| SEC24D | SEC24 family member D | -0.0222402 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0220779 |
| CDK19 | cyclin-dependent kinase 19 | -0.0220743 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0219268 |
| S100A10 | S100 calcium binding protein A10 | -0.0218685 |
| PTK2 | protein tyrosine kinase 2 | -0.0217478 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0215847 |
