| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.131939 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.12574 |
| TMEM156 | transmembrane protein 156 | 0.122836 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.121175 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0995263 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0990567 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0880624 |
| OSMR | oncostatin M receptor | 0.086673 |
| ITGA1 | integrin, alpha 1 | 0.073328 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0627117 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.061178 |
| NRP1 | neuropilin 1 | 0.060042 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0596058 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0543098 |
| PELO | pelota homolog (Drosophila) | 0.0536101 |
| AHR | aryl hydrocarbon receptor | 0.047963 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0452924 |
| IL6ST | interleukin 6 signal transducer | 0.0450739 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0449427 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0448384 |
| SMOX | spermine oxidase | 0.0444141 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.044379 |
| ETNK1 | ethanolamine kinase 1 | 0.0443486 |
| SMAD3 | SMAD family member 3 | 0.0427119 |
| EREG | epiregulin | 0.0421261 |
| TXNRD1 | thioredoxin reductase 1 | 0.041889 |
| KLHL5 | kelch-like family member 5 | 0.0416795 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0415728 |
| CAB39 | calcium binding protein 39 | 0.0388538 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.038519 |
| RUNX2 | runt-related transcription factor 2 | 0.0385034 |
| MKI67 | marker of proliferation Ki-67 | 0.0375563 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0362857 |
| ADD3 | adducin 3 (gamma) | 0.0360262 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0359982 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0357693 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0347137 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0339296 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0329872 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0329578 |
| NTN4 | netrin 4 | 0.0323844 |
| TMEM165 | transmembrane protein 165 | 0.0320072 |
| CD44 | CD44 molecule (Indian blood group) | 0.0319029 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0317787 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0312007 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0311956 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.030927 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0303797 |
| NPAS2 | neuronal PAS domain protein 2 | 0.030374 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0302472 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0297305 |
| WDR26 | WD repeat domain 26 | 0.0294895 |
| CDCP1 | CUB domain containing protein 1 | 0.0292666 |
| ERBIN | erbb2 interacting protein | 0.0290116 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0288046 |
| FOXP1 | forkhead box P1 | 0.0287277 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286459 |
| FAT1 | FAT atypical cadherin 1 | 0.0284059 |
| ITGB5 | integrin, beta 5 | 0.0283462 |
| FAF2 | Fas associated factor family member 2 | 0.0283196 |
| ZFR | zinc finger RNA binding protein | 0.0282738 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0282222 |
| RAB31 | RAB31, member RAS oncogene family | 0.0282219 |
| TPR | translocated promoter region, nuclear basket protein | 0.0281074 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0280398 |
| ETV1 | ets variant 1 | 0.0279909 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0279244 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0279033 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0277575 |
| HOMER2 | homer scaffolding protein 2 | 0.0276258 |
| SMYD3 | SET and MYND domain containing 3 | 0.0275354 |
| VMP1 | vacuole membrane protein 1 | 0.0274632 |
| PLPP6 | phospholipid phosphatase 6 | 0.0273218 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0272649 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0272621 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0271888 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0266536 |
| SSH1 | slingshot protein phosphatase 1 | 0.0264303 |
| RNF145 | ring finger protein 145 | 0.025969 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0258403 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0257853 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0252188 |
| TXNIP | thioredoxin interacting protein | 0.0248291 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0245722 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0243895 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.024378 |
| CLTC | clathrin, heavy chain (Hc) | 0.0240634 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0240041 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0239336 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0237202 |
| FHL2 | four and a half LIM domains 2 | 0.0236635 |
| NEK7 | NIMA-related kinase 7 | 0.0232326 |
| PTK2 | protein tyrosine kinase 2 | 0.0230494 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0228611 |
| SFTPA2 | surfactant protein A2 | 0.022662 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0224995 |
| ENAH | enabled homolog (Drosophila) | 0.0224734 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0222081 |
| FAM3C | family with sequence similarity 3, member C | 0.0221847 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0220667 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.166205 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.165586 |
| NRG1 | neuregulin 1 | -0.148202 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0750435 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0684368 |
| INTS6 | integrator complex subunit 6 | -0.0667474 |
| SQSTM1 | sequestosome 1 | -0.0650815 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0571454 |
| PTMA | prothymosin, alpha | -0.0556848 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.053863 |
| HMGA2 | high mobility group AT-hook 2 | -0.0529262 |
| NDRG1 | N-myc downstream regulated 1 | -0.0523507 |
| LMNA | lamin A/C | -0.051953 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0477181 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0473372 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0452209 |
| FN1 | fibronectin 1 | -0.0442067 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0432101 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0423781 |
| LRRC23 | leucine rich repeat containing 23 | -0.0421622 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0416493 |
| AEBP2 | AE binding protein 2 | -0.0391796 |
| CANX | calnexin | -0.0388325 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0377552 |
| EZR | ezrin | -0.0377011 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0365355 |
| RPL26 | ribosomal protein L26 | -0.03642 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0360774 |
| TMSB10 | thymosin beta 10 | -0.0360685 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0355515 |
| TUFT1 | tuftelin 1 | -0.0355189 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0344465 |
| CTBP2 | C-terminal binding protein 2 | -0.0337605 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0334747 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0329651 |
| HLA-B | major histocompatibility complex, class I, B | -0.0325608 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0320069 |
| CADM1 | cell adhesion molecule 1 | -0.0304633 |
| IER3 | immediate early response 3 | -0.0293488 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0292395 |
| VIM | vimentin | -0.0286924 |
| EMP1 | epithelial membrane protein 1 | -0.0284601 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0283009 |
| FLNB | filamin B, beta | -0.027428 |
| RPS6 | ribosomal protein S6 | -0.0273429 |
| MYOF | myoferlin | -0.0268735 |
| GNAS | GNAS complex locus | -0.0264405 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0261602 |
| STC2 | stanniocalcin 2 | -0.0261082 |
| S100A10 | S100 calcium binding protein A10 | -0.0258648 |
| FBXO11 | F-box protein 11 | -0.0258377 |
| RPS8 | ribosomal protein S8 | -0.0255496 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0254922 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0254665 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0249598 |
| RPL23 | ribosomal protein L23 | -0.0247041 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0245731 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0244961 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0242828 |
| RPL35A | ribosomal protein L35a | -0.0240734 |
| RAI14 | retinoic acid induced 14 | -0.0238475 |
| MORF4L2 | mortality factor 4 like 2 | -0.023813 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0238075 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0238008 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0235289 |
| RPS27 | ribosomal protein S27 | -0.0234822 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0234494 |
| RPS20 | ribosomal protein S20 | -0.0231264 |
| SIRT1 | sirtuin 1 | -0.0228711 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0228032 |
| RPS12 | ribosomal protein S12 | -0.0227091 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0226617 |
| MCL1 | myeloid cell leukemia 1 | -0.0225612 |
| AHNAK | AHNAK nucleoprotein | -0.0225305 |
| CALR | calreticulin | -0.0225276 |
| TENM4 | teneurin transmembrane protein 4 | -0.0224656 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0222434 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0222342 |
| RPL34 | ribosomal protein L34 | -0.0221034 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0215599 |
| ASPH | aspartate beta-hydroxylase | -0.0212483 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0209104 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0208348 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0208209 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0207443 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0205781 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0205274 |
| ATF3 | activating transcription factor 3 | -0.0203254 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0201466 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0201025 |
| RPS19 | ribosomal protein S19 | -0.0197362 |
| RPL36 | ribosomal protein L36 | -0.0196154 |
| NABP1 | nucleic acid binding protein 1 | -0.0195132 |
| TMSB4X | thymosin beta 4, X-linked | -0.019437 |
| FAM13A | family with sequence similarity 13, member A | -0.019368 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.019199 |
| ACTG1 | actin gamma 1 | -0.0191617 |
| RPS3 | ribosomal protein S3 | -0.0191434 |
| JUN | jun proto-oncogene | -0.0191433 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.019078 |
