W-13-440 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the W-13-440 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AGRN agrin
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATG13 autophagy related 13
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP1 bone morphogenetic protein 1
BTBD2 BTB (POZ) domain containing 2
C19ORF66 chromosome 19 open reading frame 66
C20ORF27 chromosome 20 open reading frame 27
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASKIN2 CASK interacting protein 2
CD44 CD44 molecule (Indian blood group)
CKB creatine kinase, brain
CLPTM1 cleft lip and palate associated transmembrane protein 1
COL5A1 collagen, type V, alpha 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSCAM Down syndrome cell adhesion molecule
EGFL7 EGF-like-domain, multiple 7
ESR1 estrogen receptor 1
FAM13A family with sequence similarity 13, member A
FASN fatty acid synthase
FCHO1 FCH domain only 1
FIP1L1 factor interacting with PAPOLA and CPSF1
FKBP8 FK506 binding protein 8, 38kDa
FOSL2 FOS-like antigen 2
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAB2 GRB2-associated binding protein 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPR137 G protein-coupled receptor 137
HLA-G major histocompatibility complex, class I, G
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFFO1 intermediate filament family orphan 1
IGFBP4 insulin-like growth factor binding protein 4
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB4 integrin, beta 4
JUND jun D proto-oncogene
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
METRN meteorin, glial cell differentiation regulator
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
MYL10 myosin, light chain 10, regulatory
NBEAL2 neurobeachin-like 2
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NUMA1 nuclear mitotic apparatus protein 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PC pyruvate carboxylase
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PEX11A peroxisomal biogenesis factor 11 alpha
PLD3 phospholipase D family, member 3
PLEC plectin
PODXL2 podocalyxin-like 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRB1 proline-rich protein BstNI subfamily 1
PTOV1 prostate tumor overexpressed 1
PVR poliovirus receptor
PXN paxillin
RECQL5 RecQ protein-like 5
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOD ras homolog family member D
RPLP2 ribosomal protein, large, P2
RXRA retinoid X receptor, alpha
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SMG5 SMG5 nonsense mediated mRNA decay factor
SORBS3 sorbin and SH3 domain containing 3
SRRT serrate, RNA effector molecule
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAT5A signal transducer and activator of transcription 5A
SYNGR1 synaptogyrin 1
TBL1X transducin (beta)-like 1X-linked
TCF3 transcription factor 3
THEM6 thioesterase superfamily member 6
TJP3 tight junction protein 3
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
ULK1 unc-51 like autophagy activating kinase 1
USF2 upstream transcription factor 2, c-fos interacting
VEGFB vascular endothelial growth factor B
ZER1 zyg-11 related, cell cycle regulator
ZNF24 zinc finger protein 24
ZNF276 zinc finger protein 276

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ALLC allantoicase
AMT aminomethyltransferase
ANKRD40 ankyrin repeat domain 40
ASCC3 activating signal cointegrator 1 complex subunit 3
ATF7 activating transcription factor 7
ATF7IP2 activating transcription factor 7 interacting protein 2
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C16ORF59 chromosome 16 open reading frame 59
CAMKV CaM kinase-like vesicle-associated
CAV3 caveolin 3
CCL19 chemokine (C-C motif) ligand 19
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDH18 cadherin 18, type 2
CDK6 cyclin-dependent kinase 6
CLDN17 claudin 17
CPTP ceramide-1-phosphate transfer protein
CRLF2 cytokine receptor-like factor 2
CTNNBIP1 catenin, beta interacting protein 1
DGKD diacylglycerol kinase, delta 130kDa
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYSF dysferlin
EDA2R ectodysplasin A2 receptor
EFNA1 ephrin-A1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKBPL FK506 binding protein like
GAST gastrin
GDF2 growth differentiation factor 2
GLT8D2 glycosyltransferase 8 domain containing 2
GMEB1 glucocorticoid modulatory element binding protein 1
GP9 glycoprotein IX (platelet)
GPR157 G protein-coupled receptor 157
GPX2 glutathione peroxidase 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H4J histone cluster 1, H4j
IL18BP interleukin 18 binding protein
IL36RN interleukin 36 receptor antagonist
IL4R interleukin 4 receptor
INSIG2 insulin induced gene 2
KIAA1598
KIF23 kinesin family member 23
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KREMEN2 kringle containing transmembrane protein 2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LENEP lens epithelial protein
LMTK1 lemur tail kinase 1
LRRC61 leucine rich repeat containing 61
LYRM4 LYR motif containing 4
MLXIPL MLX interacting protein-like
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOGAT2 monoacylglycerol O-acyltransferase 2
NELL2 NEL-like 2 (chicken)
NPPA natriuretic peptide A
NPY neuropeptide Y
NUPL2 nucleoporin like 2
OLFML2B olfactomedin-like 2B
PCDHB3 protocadherin beta 3
PCTP phosphatidylcholine transfer protein
PEX12 peroxisomal biogenesis factor 12
PHOX2A paired-like homeobox 2a
PLA2G12A phospholipase A2, group XIIA
PLCD1 phospholipase C, delta 1
PPL periplakin
PQLC2 PQ loop repeat containing 2
PQLC3 PQ loop repeat containing 3
PTK7 protein tyrosine kinase 7 (inactive)
RAB8B RAB8B, member RAS oncogene family
RBBP5 retinoblastoma binding protein 5
RECQL4 RecQ protein-like 4
RGS17 regulator of G-protein signaling 17
RNF43 ring finger protein 43
S100A1 S100 calcium binding protein A1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCML2 sex comb on midleg-like 2 (Drosophila)
SH2D2A SH2 domain containing 2A
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPEF1 sperm flagellar 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SYN1 synapsin I
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
THOC1 THO complex 1
TMEM38B transmembrane protein 38B
TMEM59L transmembrane protein 59-like
TOE1 target of EGR1, member 1 (nuclear)
USP6NL USP6 N-terminal like
VCPKMT valosin containing protein lysine (K) methyltransferase
XPO4 exportin 4
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZNF267 zinc finger protein 267
ZNHIT2 zinc finger, HIT-type containing 2