| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/9830392 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in WAY 170523 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRP1 | neuropilin 1 | 1.81 |
| COL18A1 | collagen, type XVIII, alpha 1 | 1.58 |
| COL12A1 | collagen, type XII, alpha 1 | 1.56 |
| COL6A2 | collagen, type VI, alpha 2 | 1.37 |
| ABHD4 | abhydrolase domain containing 4 | 1.26 |
| MCL1 | myeloid cell leukemia 1 | 1.13 |
| BHLHA15 | basic helix-loop-helix family, member a15 | 1.07 |
| SEC11C | SEC11 homolog C (S. cerevisiae) | 1.04 |
| SEC24D | SEC24 family member D | 0.94 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.83 |
| HID1 | HID1 domain containing | 0.8 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.78 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.78 |
| JAG1 | jagged 1 | 0.75 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.75 |
| LAMA3 | laminin, alpha 3 | 0.74 |
| CCN3 | cellular communication network factor 3 | 0.69 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.68 |
| HMOX1 | heme oxygenase 1 | 0.66 |
| PRELID1 | PRELI domain containing 1 | 0.65 |
| NDRG1 | N-myc downstream regulated 1 | 0.64 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.61 |
| UPP1 | uridine phosphorylase 1 | 0.59 |
| FAT1 | FAT atypical cadherin 1 | 0.58 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.55 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) | 0.55 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.55 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.55 |
| SUCO | SUN domain containing ossification factor | 0.54 |
| CHPF | chondroitin polymerizing factor | 0.54 |
| PRF1 | perforin 1 (pore forming protein) | 0.54 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.54 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.53 |
| C18ORF32 | chromosome 18 open reading frame 32 | 0.53 |
| PRELID3B | PRELI domain containing 3B | 0.53 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.53 |
| FAM185A | family with sequence similarity 185, member A | 0.52 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.52 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.52 |
| ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 0.52 |
| IL10RB | interleukin 10 receptor, beta | 0.5 |
| EPN3 | epsin 3 | 0.5 |
| ADIPOR1 | adiponectin receptor 1 | 0.5 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.5 |
| KLHDC10 | kelch domain containing 10 | 0.5 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.49 |
| NIBAN1 | niban apoptosis regulator 1 | 0.49 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 0.49 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 | 0.49 |
| SEC61B | Sec61 beta subunit | 0.48 |
| USP27X | ubiquitin specific peptidase 27, X-linked | 0.48 |
| HSP90AB4P | heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene | 0.48 |
| RWDD2A | RWD domain containing 2A | 0.48 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.48 |
| CPA4 | carboxypeptidase A4 | 0.47 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 | 0.46 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.45 |
| PCDH1 | protocadherin 1 | 0.45 |
| LAMB3 | laminin, beta 3 | 0.45 |
| CAMTA2 | calmodulin binding transcription activator 2 | 0.45 |
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.45 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.45 |
| LAMC2 | laminin, gamma 2 | 0.45 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.45 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.45 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.45 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.44 |
| NEU3 | sialidase 3 (membrane sialidase) | 0.44 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.44 |
| SHANK3 | SH3 and multiple ankyrin repeat domains 3 | 0.44 |
| TMEM184A | transmembrane protein 184A | 0.44 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.44 |
| ACVR1B | activin A receptor, type IB | 0.44 |
| GLRX | glutaredoxin (thioltransferase) | 0.43 |
| SRPRB | signal recognition particle receptor, B subunit | 0.43 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.43 |
| LOXL2 | lysyl oxidase-like 2 | 0.42 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.42 |
| SELENOK | selenoprotein K | 0.41 |
| FAS | Fas cell surface death receptor | 0.41 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.41 |
| ATF6 | activating transcription factor 6 | 0.41 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.41 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.41 |
| TM2D3 | TM2 domain containing 3 | 0.4 |
| MUC16 | mucin 16, cell surface associated | 0.4 |
| GMPPA | GDP-mannose pyrophosphorylase A | 0.4 |
| PGM3 | phosphoglucomutase 3 | 0.39 |
| EED | embryonic ectoderm development | 0.39 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.39 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.39 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.39 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.39 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.38 |
| FHL1 | four and a half LIM domains 1 | 0.38 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.38 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.38 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) | 0.38 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.38 |
| ALG2 | ALG2, alpha-1,3/1,6-mannosyltransferase | 0.38 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -1.37 |
| COL17A1 | collagen, type XVII, alpha 1 | -1.03 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | -0.96 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) | -0.92 |
| TOR4A | torsin family 4, member A | -0.91 |
| SMIM19 | small integral membrane protein 19 | -0.85 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.83 |
| TMC5 | transmembrane channel-like 5 | -0.82 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.73 |
| TESC | tescalcin | -0.72 |
| FUNDC1 | FUN14 domain containing 1 | -0.71 |
| RCE1 | Ras converting CAAX endopeptidase 1 | -0.7 |
| PLIN2 | perilipin 2 | -0.7 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.67 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.66 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit | -0.65 |
| AASDH | aminoadipate-semialdehyde dehydrogenase | -0.64 |
| TOR3A | torsin family 3, member A | -0.64 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.63 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.62 |
| PSEN2 | presenilin 2 | -0.6 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -0.6 |
| MAGEE1 | melanoma antigen family E1 | -0.6 |
| CISD3 | CDGSH iron sulfur domain 3 | -0.59 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.59 |
| METTL17 | methyltransferase like 17 | -0.58 |
| ZNF354B | zinc finger protein 354B | -0.58 |
| ARSK | arylsulfatase family, member K | -0.57 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 | -0.57 |
| ZNF142 | zinc finger protein 142 | -0.57 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.56 |
| DDX12P | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene | -0.56 |
| THAP9 | THAP domain containing 9 | -0.56 |
| QSOX2 | quiescin Q6 sulfhydryl oxidase 2 | -0.55 |
| PLEKHN1 | pleckstrin homology domain containing, family N member 1 | -0.55 |
| ZNF428 | zinc finger protein 428 | -0.55 |
| SELENOH | selenoprotein H | -0.54 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | -0.54 |
| MUTYH | mutY homolog | -0.53 |
| CD320 | CD320 molecule | -0.53 |
| ERVMER34-1 | endogenous retrovirus group MER34, member 1 | -0.53 |
| PTMA | prothymosin, alpha | -0.52 |
| PLSCR1 | phospholipid scramblase 1 | -0.52 |
| DHFR | dihydrofolate reductase | -0.51 |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | -0.51 |
| CISD1 | CDGSH iron sulfur domain 1 | -0.5 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.5 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -0.5 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.5 |
| SLC15A4 | solute carrier family 15 (oligopeptide transporter), member 4 | -0.49 |
| ANKRD10 | ankyrin repeat domain 10 | -0.48 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | -0.48 |
| CD59 | CD59 molecule, complement regulatory protein | -0.48 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -0.47 |
| H1-2 | H1.2 linker histone, cluster member | -0.47 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.47 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.47 |
| LIAS | lipoic acid synthetase | -0.46 |
| PPAT | phosphoribosyl pyrophosphate amidotransferase | -0.46 |
| CYB5D2 | cytochrome b5 domain containing 2 | -0.46 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | -0.46 |
| AAGAB | alpha- and gamma-adaptin binding protein | -0.45 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.45 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.45 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.45 |
| SLC16A6 | solute carrier family 16, member 6 | -0.45 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.44 |
| HES1 | hes family bHLH transcription factor 1 | -0.44 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | -0.43 |
| ZNF721 | zinc finger protein 721 | -0.43 |
| VGLL4 | vestigial-like family member 4 | -0.43 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.43 |
| BCL2L12 | BCL2-like 12 (proline rich) | -0.43 |
| CDCA4 | cell division cycle associated 4 | -0.43 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) | -0.43 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.42 |
| TSC22D1 | TSC22 domain family, member 1 | -0.42 |
| TRIM29 | tripartite motif containing 29 | -0.42 |
| MTFR1L | mitochondrial fission regulator 1-like | -0.42 |
| ABHD17A | abhydrolase domain containing 17A | -0.42 |
| TOP1MT | topoisomerase (DNA) I, mitochondrial | -0.42 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | -0.41 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | -0.41 |
| SCARA3 | scavenger receptor class A, member 3 | -0.41 |
| COX19 | COX19 cytochrome c oxidase assembly factor | -0.41 |
| PEG10 | paternally expressed 10 | -0.4 |
| PPP1R2B | PPP1R2 family member B | -0.4 |
| VSIR | V-set immunoregulatory receptor | -0.4 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.4 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | -0.4 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit | -0.4 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.4 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | -0.39 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | -0.39 |
| BOD1 | biorientation of chromosomes in cell division 1 | -0.39 |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 | -0.39 |
| CNTLN | centlein, centrosomal protein | -0.39 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.39 |
