| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/16727102 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in WAY 316606 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMG2 | semenogelin II | 7.05 |
| SEMG1 | semenogelin I | 6.71 |
| SLC6A17 | solute carrier family 6 (neutral amino acid transporter), member 17 | 1.94 |
| BBS9 | Bardet-Biedl syndrome 9 | 1.21 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | 1.19 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 1.08 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 1.08 |
| TSPAN3 | tetraspanin 3 | 1.02 |
| PIP | prolactin-induced protein | 0.96 |
| PTCD2 | pentatricopeptide repeat domain 2 | 0.89 |
| NEK4 | NIMA-related kinase 4 | 0.87 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.82 |
| PRDM16 | PR domain containing 16 | 0.71 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 0.68 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | 0.64 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.63 |
| CCDC15 | coiled-coil domain containing 15 | 0.58 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.54 |
| MYH4 | myosin, heavy chain 4, skeletal muscle | 0.53 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 0.5 |
| APOLTP | apolipoprotein lipid transfer particle homolog | 0.46 |
| PITX1 | paired-like homeodomain 1 | 0.46 |
| ACTBL2 | actin, beta-like 2 | 0.46 |
| MID1IP1 | MID1 interacting protein 1 | 0.46 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.45 |
| ZNF449 | zinc finger protein 449 | 0.44 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.43 |
| GRAMD2B | GRAM domain containing 2B | 0.43 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 | 0.42 |
| SPATA13 | spermatogenesis associated 13 | 0.41 |
| PER2 | period circadian clock 2 | 0.4 |
| RPE | ribulose-5-phosphate-3-epimerase | 0.4 |
| XTBD1 | XRN2 binding domain containing 1 | 0.4 |
| HAS3 | hyaluronan synthase 3 | 0.39 |
| CCDC167 | coiled-coil domain containing 167 | 0.39 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.39 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.38 |
| ITGA6 | integrin, alpha 6 | 0.38 |
| CDC26 | cell division cycle 26 | 0.38 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.38 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like | 0.38 |
| MRVI1 | murine retrovirus integration site 1 homolog | 0.37 |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like | 0.37 |
| H2AZ1 | H2A.Z variant histone 1 | 0.36 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | 0.36 |
| THAP9 | THAP domain containing 9 | 0.36 |
| DGCR2 | DiGeorge syndrome critical region gene 2 | 0.35 |
| DHFR | dihydrofolate reductase | 0.35 |
| ZMYM6 | zinc finger, MYM-type 6 | 0.35 |
| ZNF711 | zinc finger protein 711 | 0.35 |
| NDE1 | nudE neurodevelopment protein 1 | 0.35 |
| CBX7 | chromobox homolog 7 | 0.34 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.34 |
| ZNRF2 | zinc and ring finger 2, E3 ubiquitin protein ligase | 0.34 |
| POLG | polymerase (DNA directed), gamma | 0.34 |
| H3-3A | H3.3 histone A | 0.33 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.33 |
| INPP5J | inositol polyphosphate-5-phosphatase J | 0.33 |
| WDR90 | WD repeat domain 90 | 0.33 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.33 |
| CTHRC1 | collagen triple helix repeat containing 1 | 0.32 |
| SLX4 | SLX4 structure-specific endonuclease subunit | 0.32 |
| TSPYL2 | TSPY-like 2 | 0.32 |
| APOB | apolipoprotein B | 0.32 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.32 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 | 0.32 |
| FAM171B | family with sequence similarity 171, member B | 0.32 |
| B2M | beta-2-microglobulin | 0.32 |
| NCOA4 | nuclear receptor coactivator 4 | 0.32 |
| HMGB1 | high mobility group box 1 | 0.32 |
| ANAPC2 | anaphase promoting complex subunit 2 | 0.31 |
| CLSTN3 | calsyntenin 3 | 0.31 |
| KLHL15 | kelch-like family member 15 | 0.31 |
| MLPH | melanophilin | 0.31 |
| CCDC170 | coiled-coil domain containing 170 | 0.3 |
| CENPN | centromere protein N | 0.3 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.3 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | 0.3 |
| COL11A1 | collagen, type XI, alpha 1 | 0.3 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | 0.3 |
| TMEM40 | transmembrane protein 40 | 0.3 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.29 |
| ZNF611 | zinc finger protein 611 | 0.29 |
| MREG | melanoregulin | 0.29 |
| METTL6 | methyltransferase like 6 | 0.29 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.29 |
| TMEM263 | transmembrane protein 263 | 0.28 |
| MEX3A | mex-3 RNA binding family member A | 0.28 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.28 |
| NEK2 | NIMA-related kinase 2 | 0.28 |
| HGH1 | HGH1 homolog (S. cerevisiae) | 0.28 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.28 |
| STEAP2 | STEAP family member 2, metalloreductase | 0.28 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.27 |
| FAM20C | family with sequence similarity 20, member C | 0.27 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.27 |
| ZFAND2A | zinc finger, AN1-type domain 2A | 0.27 |
| ANAPC16 | anaphase promoting complex subunit 16 | 0.26 |
| CD63 | CD63 molecule | 0.26 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.26 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMEM41B | transmembrane protein 41B | -1.1 |
| CALD1 | caldesmon 1 | -0.93 |
| BAIAP2 | BAI1-associated protein 2 | -0.89 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -0.82 |
| NPHP1 | nephronophthisis 1 (juvenile) | -0.6 |
| NAAA | N-acylethanolamine acid amidase | -0.59 |
| METAP1D | methionyl aminopeptidase type 1D (mitochondrial) | -0.59 |
| FGFR4 | fibroblast growth factor receptor 4 | -0.52 |
| TMC4 | transmembrane channel-like 4 | -0.51 |
| ANK2 | ankyrin 2, neuronal | -0.5 |
| ADAM22 | ADAM metallopeptidase domain 22 | -0.5 |
| CNTNAP3 | contactin associated protein-like 3 | -0.49 |
| WASHC3 | WASH complex subunit 3 | -0.47 |
| BAK1 | BCL2-antagonist/killer 1 | -0.47 |
| LINGO1 | leucine rich repeat and Ig domain containing 1 | -0.46 |
| RNF130 | ring finger protein 130 | -0.44 |
| SULF2 | sulfatase 2 | -0.43 |
| ADSS1 | adenylosuccinate synthase 1 | -0.43 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | -0.42 |
| CLK1 | CDC-like kinase 1 | -0.42 |
| ZNF142 | zinc finger protein 142 | -0.41 |
| PEMT | phosphatidylethanolamine N-methyltransferase | -0.41 |
| MON1A | MON1 secretory trafficking family member A | -0.4 |
| NMNAT3 | nicotinamide nucleotide adenylyltransferase 3 | -0.4 |
| FOXO1 | forkhead box O1 | -0.4 |
| KIAA1210 | KIAA1210 | -0.38 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -0.38 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | -0.37 |
| ZNF335 | zinc finger protein 335 | -0.37 |
| ZFAT | zinc finger and AT hook domain containing | -0.35 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.35 |
| HBA1 | hemoglobin, alpha 1 | -0.35 |
| TXNRD3 | thioredoxin reductase 3 | -0.35 |
| MAST3 | microtubule associated serine/threonine kinase 3 | -0.35 |
| DERPC | DERPC proline and glycine rich nuclear protein | -0.35 |
| OGFRL1 | opioid growth factor receptor-like 1 | -0.35 |
| SERINC5 | serine incorporator 5 | -0.34 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.34 |
| LRP6 | low density lipoprotein receptor-related protein 6 | -0.34 |
| LACC1 | laccase (multicopper oxidoreductase) domain containing 1 | -0.33 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.33 |
| MAP2 | microtubule-associated protein 2 | -0.33 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.32 |
| CCDC150 | coiled-coil domain containing 150 | -0.32 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | -0.32 |
| SNX29 | sorting nexin 29 | -0.32 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.32 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.31 |
| DENND6A | DENN/MADD domain containing 6A | -0.31 |
| PRR5 | proline rich 5 (renal) | -0.3 |
| RNF139 | ring finger protein 139 | -0.29 |
| ADCK5 | aarF domain containing kinase 5 | -0.29 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.29 |
| GALNT4 | polypeptide N-acetylgalactosaminyltransferase 4 | -0.28 |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | -0.28 |
| TMEM186 | transmembrane protein 186 | -0.28 |
| CBLC | Cbl proto-oncogene C, E3 ubiquitin protein ligase | -0.28 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.28 |
| KNDC1 | kinase non-catalytic C-lobe domain (KIND) containing 1 | -0.28 |
| STX6 | syntaxin 6 | -0.28 |
| SYNPO | synaptopodin | -0.27 |
| HM13 | histocompatibility (minor) 13 | -0.27 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.27 |
| MBTD1 | mbt domain containing 1 | -0.27 |
| FAM199X | family with sequence similarity 199, X-linked | -0.27 |
| ADAP1 | ArfGAP with dual PH domains 1 | -0.27 |
| FAM219A | family with sequence similarity 219, member A | -0.27 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 | -0.27 |
| ZNF557 | zinc finger protein 557 | -0.27 |
| POLH | polymerase (DNA directed), eta | -0.27 |
| FUNDC1 | FUN14 domain containing 1 | -0.27 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.26 |
| MTRF1L | mitochondrial translational release factor 1-like | -0.26 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | -0.26 |
| SP140L | SP140 nuclear body protein-like | -0.26 |
| TMEM115 | transmembrane protein 115 | -0.26 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 | -0.26 |
| SRD5A3 | steroid 5 alpha-reductase 3 | -0.26 |
| CDK18 | cyclin-dependent kinase 18 | -0.26 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | -0.26 |
| CUX1 | cut-like homeobox 1 | -0.26 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.26 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.26 |
| HINFP | histone H4 transcription factor | -0.26 |
| PAQR4 | progestin and adipoQ receptor family member IV | -0.26 |
| ZFHX3 | zinc finger homeobox 3 | -0.25 |
| PLK2 | polo-like kinase 2 | -0.25 |
| ZNF483 | zinc finger protein 483 | -0.25 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.25 |
| MARS2 | methionyl-tRNA synthetase 2, mitochondrial | -0.25 |
| PLA2G12A | phospholipase A2, group XIIA | -0.25 |
| PLXNA1 | plexin A1 | -0.25 |
| PXN | paxillin | -0.25 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.25 |
| CRBN | cereblon | -0.25 |
| TMEM67 | transmembrane protein 67 | -0.25 |
| TMEM161B | transmembrane protein 161B | -0.25 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 | -0.24 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.24 |
| RARG | retinoic acid receptor, gamma | -0.24 |
