WDR5 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description WD repeat domain 5|This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 11091)
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Genes

668 genes differentially expressed following the WDR5 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ADAM23 ADAM metallopeptidase domain 23 3.26876
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 3.24509
LBP lipopolysaccharide binding protein 3.24509
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.24509
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 3.24509
MED16 mediator complex subunit 16 3.24509
ZNF713 zinc finger protein 713 3.24509
TMLHE trimethyllysine hydroxylase, epsilon 3.24509
MALRD1 MAM and LDL receptor class A domain containing 1 3.24509
MYCT1 myc target 1 3.24509
VAMP3 vesicle-associated membrane protein 3 3.24509
METTL25 methyltransferase like 25 3.24509
SFMBT2 Scm-like with four mbt domains 2 3.24509
C12ORF76 chromosome 12 open reading frame 76 3.24509
TOR1B torsin family 1, member B (torsin B) 3.24509
ASCC2 activating signal cointegrator 1 complex subunit 2 3.24509
BSN bassoon presynaptic cytomatrix protein 3.24509
TRPV1 transient receptor potential cation channel, subfamily V, member 1 3.24509
PAIP2B poly(A) binding protein interacting protein 2B 3.24509
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 3.24509
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) 3.24509
PQBP1 polyglutamine binding protein 1 3.24509
ERN1 endoplasmic reticulum to nucleus signaling 1 3.24509
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.24509
BLZF1 basic leucine zipper nuclear factor 1 3.24509
MAP7D1 MAP7 domain containing 1 3.24509
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35 3.24509
DMAP1 DNA methyltransferase 1 associated protein 1 3.24509
GPR156 G protein-coupled receptor 156 3.24509
ZNF468 zinc finger protein 468 3.24509
IQCC IQ motif containing C 3.24509
PAN2 PAN2 poly(A) specific ribonuclease subunit 3.24509
TBRG1 transforming growth factor beta regulator 1 3.24509
IL17RA interleukin 17 receptor A 3.24509
CCDC142 coiled-coil domain containing 142 3.24509
GFOD2 glucose-fructose oxidoreductase domain containing 2 3.24509
CPT1A carnitine palmitoyltransferase 1A (liver) 3.24509
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.24509
ANKRD18A ankyrin repeat domain 18A 3.24509
LIX1L Lix1 homolog (chicken) like 3.24509
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) 3.24509
TTLL7 tubulin tyrosine ligase-like family member 7 3.24509
SPRY3 sprouty homolog 3 (Drosophila) 3.24509
LHX1 LIM homeobox 1 3.24509
PLA2G15 phospholipase A2, group XV 3.24509
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 3.24509
MYO5C myosin VC 3.24509
EPHB1 EPH receptor B1 3.24509
SPAG1 sperm associated antigen 1 3.24509
SPON1 spondin 1, extracellular matrix protein 3.24509
SPTB spectrin, beta, erythrocytic 3.24509
DGKB diacylglycerol kinase, beta 90kDa 3.24509
ZNF566 zinc finger protein 566 3.24509
PITX3 paired-like homeodomain 3 3.24509
OTOG otogelin 3.24509
IFI27 interferon, alpha-inducible protein 27 3.24509
GRM5 glutamate receptor, metabotropic 5 3.24509
DHRS4 dehydrogenase/reductase (SDR family) member 4 3.24509
DHRS3 dehydrogenase/reductase (SDR family) member 3 3.24509
ENG endoglin 3.24509
C1ORF174 chromosome 1 open reading frame 174 3.24509
MAN2C1 mannosidase, alpha, class 2C, member 1 3.24509
ZNF664-RFLNA ZNF664-RFLNA readthrough 3.24509
MMP23B matrix metallopeptidase 23B 3.24509
FAM185A family with sequence similarity 185, member A 3.24509
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 3.24509
TRUB1 TruB pseudouridine (psi) synthase family member 1 3.24509
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 3.24509
ADGRG2 adhesion G protein-coupled receptor G2 3.24509
PCGF1 polycomb group ring finger 1 3.24509
CHL1 cell adhesion molecule L1-like 3.24509
CMTR1 cap methyltransferase 1 3.24509
ZFYVE26 zinc finger, FYVE domain containing 26 3.24509
FBXL15 F-box and leucine-rich repeat protein 15 3.24509
KISS1R KISS1 receptor 3.24509
GORAB golgin, RAB6-interacting 3.24509
MTX3 metaxin 3 3.24509
MPI mannose phosphate isomerase 3.24509
MPZ myelin protein zero 3.24509
CLDN19 claudin 19 3.24509
PHF11 PHD finger protein 11 3.24509
AMPD3 adenosine monophosphate deaminase 3 3.24509
SLX4 SLX4 structure-specific endonuclease subunit 3.24509
FAM78A family with sequence similarity 78, member A 3.24509
MRAP2 melanocortin 2 receptor accessory protein 2 3.24509
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 3.24509
ACP2 acid phosphatase 2, lysosomal 3.24509
SNIP1 Smad nuclear interacting protein 1 3.24509
STXBP2 syntaxin binding protein 2 3.24509
SYT12 synaptotagmin XII 3.24509
ZNF23 zinc finger protein 23 3.24509
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 3.24509
AGA aspartylglucosaminidase 3.24509
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 3.24509
PTGFRN prostaglandin F2 receptor inhibitor 3.24509
KLHL36 kelch-like family member 36 3.24509
TMEM92 transmembrane protein 92 3.24509
PEX1 peroxisomal biogenesis factor 1 3.24509
WSCD1 WSC domain containing 1 3.24509
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 3.24509
GIN1 gypsy retrotransposon integrase 1 3.24509
CNGA1 cyclic nucleotide gated channel alpha 1 3.24509
TKFC triokinase/FMN cyclase 3.24509
TMEM38A transmembrane protein 38A 3.24509
SRPX sushi-repeat containing protein, X-linked 3.24509
VWCE von Willebrand factor C and EGF domains 3.24509
PM20D2 peptidase M20 domain containing 2 3.24509
MCMDC2 minichromosome maintenance domain containing 2 3.24509
PHTF2 putative homeodomain transcription factor 2 3.24509
CFAP52 cilia and flagella associated protein 52 3.24509
ZNF688 zinc finger protein 688 3.24509
ZNF689 zinc finger protein 689 3.24509
ZNF460 zinc finger protein 460 3.24509
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) 3.24509
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 3.24509
RNF26 ring finger protein 26 3.24509
LENG1 leukocyte receptor cluster (LRC) member 1 3.24509
APOLD1 apolipoprotein L domain containing 1 3.24509
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 3.24509
ZNF865 zinc finger protein 865 3.24509
ZNF512B zinc finger protein 512B 3.24509
SH2B3 SH2B adaptor protein 3 3.24509
ARL8A ADP-ribosylation factor-like 8A 3.24509
ATXN7L3 ataxin 7-like 3 3.24509
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 3.24509
RAB30 RAB30, member RAS oncogene family 3.24509
CINP cyclin-dependent kinase 2 interacting protein 3.24509
METRNL meteorin, glial cell differentiation regulator-like 3.24509
RNH1 ribonuclease/angiogenin inhibitor 1 3.24509
MFSD1 major facilitator superfamily domain containing 1 3.24509
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 3.24509
RACGAP1 Rac GTPase activating protein 1 3.24509
RAB38 RAB38, member RAS oncogene family 3.24509
MN1 meningioma (disrupted in balanced translocation) 1 3.24509
CCNL1 cyclin L1 3.24509
PON3 paraoxonase 3 3.24509
TMEM260 transmembrane protein 260 3.24509
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 3.24509
SCGB3A2 secretoglobin, family 3A, member 2 3.24509
NUP50 nucleoporin 50kDa 3.24509
VEZT vezatin, adherens junctions transmembrane protein 3.24509
HAVCR2 hepatitis A virus cellular receptor 2 3.24509
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.24509
CARD10 caspase recruitment domain family, member 10 3.24509
FMNL3 formin-like 3 3.24509
NDRG4 NDRG family member 4 3.24509
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.24509
ZNF329 zinc finger protein 329 3.24509
CRYM crystallin, mu 3.24509
ANGPT1 angiopoietin 1 3.24509
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 3.24509
ZDHHC19 zinc finger, DHHC-type containing 19 3.24509
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 3.24509
ZMAT1 zinc finger, matrin-type 1 3.24509
TMEM14A transmembrane protein 14A 3.24509
NEXN nexilin (F actin binding protein) 3.24509
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 3.24509
ZNF19 zinc finger protein 19 3.24509
CYB5R1 cytochrome b5 reductase 1 3.24509
F3 coagulation factor III (thromboplastin, tissue factor) 3.24509
DYSF dysferlin 3.24509
FRG1 FSHD region gene 1 3.24509
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 3.24509
CTBS chitobiase, di-N-acetyl- 3.24509
SIAH2 siah E3 ubiquitin protein ligase 2 3.24509
ZNF425 zinc finger protein 425 3.24509
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 3.24509
SFR1 SWI5-dependent recombination repair 1 3.24509
SHISA4 shisa family member 4 3.24509
TMEM138 transmembrane protein 138 3.24509
C19ORF44 chromosome 19 open reading frame 44 3.24509
CRHR1 corticotropin releasing hormone receptor 1 3.24509
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 3.24509
ANKRD23 ankyrin repeat domain 23 3.24509
SORCS3 sortilin-related VPS10 domain containing receptor 3 3.24509
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 3.24509
POLN polymerase (DNA directed) nu 3.24509
SLC45A4 solute carrier family 45, member 4 3.24509
CCDC92B coiled-coil domain containing 92B 3.24509
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.24509
PVALEF parvalbumin like EF-hand containing 3.24509
THAP1 THAP domain containing, apoptosis associated protein 1 3.24509
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 3.24509
KIAA2013 KIAA2013 3.24509
SARM1 sterile alpha and TIR motif containing 1 3.24509
SHISAL2A shisa like 2A 3.24509
LRMDA leucine rich melanocyte differentiation associated 3.24509
PBK PDZ binding kinase 3.24509
KLF6 Kruppel-like factor 6 3.24509
ZNF543 zinc finger protein 543 3.24509
SDE2 SDE2 telomere maintenance homolog (S. pombe) 3.24509
H2BC3 H2B clustered histone 3 3.24509
HSPA1B heat shock 70kDa protein 1B 3.24509
EVA1C eva-1 homolog C (C. elegans) 3.24509
ENOX1 ecto-NOX disulfide-thiol exchanger 1 3.24509
SLC6A16 solute carrier family 6, member 16 3.24509
C2ORF92 chromosome 2 open reading frame 92 3.24509
CFAP92 cilia and flagella associated protein 92 (putative) 3.24509
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 3.24509
CREG2 cellular repressor of E1A-stimulated genes 2 3.24509
CDH18 cadherin 18, type 2 3.24509
FAM193B family with sequence similarity 193, member B 3.24509
FAM20A family with sequence similarity 20, member A 3.24509
CNTNAP1 contactin associated protein 1 3.24509
KLRB1 killer cell lectin-like receptor subfamily B, member 1 3.24509
SLC25A53 solute carrier family 25, member 53 3.24509
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 3.24509
PCSK2 proprotein convertase subtilisin/kexin type 2 3.24509
SKA3 spindle and kinetochore associated complex subunit 3 3.24509
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 3.24509
BCL6 B-cell CLL/lymphoma 6 3.24509
EXD3 exonuclease 3'-5' domain containing 3 3.24509
RIPK2 receptor-interacting serine-threonine kinase 2 3.24509
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 3.24509
VCF2 VCP nuclear cofactor family member 2 3.24509
MAGEH1 melanoma antigen family H1 3.24509
PECR peroxisomal trans-2-enoyl-CoA reductase 3.24509
DDIT4 DNA-damage-inducible transcript 4 3.24509
ETHE1 ethylmalonic encephalopathy 1 3.24509
ADRA2A adrenoceptor alpha 2A 3.24509
SYT3 synaptotagmin III 3.24509
PDE11A phosphodiesterase 11A 3.24509
TZMP1 transition zone microprotein 1 3.24509
SLC71A1 solute carrier family 71 member 1 3.24509
ZNF384 zinc finger protein 384 3.24509
IGBP1 immunoglobulin (CD79A) binding protein 1 3.24509
DRC2 dynein regulatory complex subunit 2 3.24509
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.24509
USP16 ubiquitin specific peptidase 16 3.24509
KLC3 kinesin light chain 3 3.24509
TAPT1 transmembrane anterior posterior transformation 1 3.24509
LRRC7 leucine rich repeat containing 7 3.24509
SMIM11 small integral membrane protein 11 3.24509
AQP11 aquaporin 11 3.24509
KBTBD8 kelch repeat and BTB (POZ) domain containing 8 3.24509
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta 3.24509
TRABD2A TraB domain containing 2A 3.24509
SSBP4 single stranded DNA binding protein 4 3.24509
MLYCD malonyl-CoA decarboxylase 3.24509
PLCD1 phospholipase C, delta 1 3.24509
CKMT1A creatine kinase, mitochondrial 1A 3.24509
INSYN1 inhibitory synaptic factor 1 3.24509
CHIC1 cysteine-rich hydrophobic domain 1 3.24509
RTL10 retrotransposon Gag like 10 3.24509
FANCE Fanconi anemia, complementation group E 3.24509
ZNF599 zinc finger protein 599 3.24509
PRR5L proline rich 5 like 3.24509
CENPS centromere protein S 3.24509
CLCNKB chloride channel, voltage-sensitive Kb 3.24509
AGBL3 ATP/GTP binding protein-like 3 3.24509
NCKAP5 NCK-associated protein 5 3.24509
OTOGL otogelin-like 3.24509
MLKL mixed lineage kinase domain-like 3.24509
GRIK3 glutamate receptor, ionotropic, kainate 3 3.24509
PPP1R3F protein phosphatase 1, regulatory subunit 3F 3.24509
HLA-DMA major histocompatibility complex, class II, DM alpha 3.24509
UTP25 UTP25 small subunit processome component 3.24509
STARD10 StAR-related lipid transfer (START) domain containing 10 3.24509
GXYLT2 glucoside xylosyltransferase 2 3.24509
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 3.24509
RAMAC RNA guanine-7 methyltransferase activating subunit 3.24509
ZNF737 zinc finger protein 737 3.24509
XYLT2 xylosyltransferase II 3.24509
NCAPH non-SMC condensin I complex, subunit H 3.24509
PORCN porcupine homolog (Drosophila) 3.24509
SHBG sex hormone-binding globulin 3.24509
RIOK1 RIO kinase 1 3.24509
AHSP alpha hemoglobin stabilizing protein 3.24509
CRELD1 cysteine-rich with EGF-like domains 1 3.24509
ARL4D ADP-ribosylation factor-like 4D 3.24509
ZNF774 zinc finger protein 774 3.24509
P3H2 prolyl 3-hydroxylase 2 3.24509
SMTN smoothelin 3.24509
OTX2 orthodenticle homeobox 2 3.24509
SLIT3 slit homolog 3 (Drosophila) 3.24509
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 3.24509
SPATA5L1 spermatogenesis associated 5-like 1 3.24509
RIPOR1 RHO family interacting cell polarization regulator 1 3.24509
DNAH5 dynein, axonemal, heavy chain 5 3.24509
GRK2 G protein-coupled receptor kinase 2 3.24509
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 3.24509
KLHL21 kelch-like family member 21 3.24509
MYG1 MYG1 exonuclease 3.24509
POLK polymerase (DNA directed) kappa 3.24509
POLI polymerase (DNA directed) iota 3.24509
CHRDL1 chordin-like 1 3.24509
DBT dihydrolipoamide branched chain transacylase E2 3.24509
STOX1 storkhead box 1 3.24509
KLHL3 kelch-like family member 3 3.24509
CLC Charcot-Leyden crystal galectin 3.24509
TRMT9B tRNA methyltransferase 9B (putative) 3.24509
H2AC13 H2A clustered histone 13 3.24509
BIN1 bridging integrator 1 3.24509
LRRC4B leucine rich repeat containing 4B 3.24509
VEGFD vascular endothelial growth factor D 3.24509
RUBCNL rubicon like autophagy enhancer 3.24509
PIANP PILR alpha associated neural protein 3.24509
TIPRL TOR signaling pathway regulator 3.24509
PHLDA2 pleckstrin homology-like domain, family A, member 2 3.24509
MPV17L2 MPV17 mitochondrial membrane protein-like 2 3.24509
DYNC2I2 dynein 2 intermediate chain 2 3.24509
ULK3 unc-51 like kinase 3 3.24509
GRB14 growth factor receptor-bound protein 14 3.24509
MYBBP1A MYB binding protein (P160) 1a 3.24509
GP6 glycoprotein VI (platelet) 3.24509
RARG retinoic acid receptor, gamma 3.24509
RGS10 regulator of G-protein signaling 10 3.24509
DUSP23 dual specificity phosphatase 23 3.24509
ATPSCKMT ATP synthase c subunit lysine N-methyltransferase 3.24509
ACBD5 acyl-CoA binding domain containing 5 3.24509
BICRA BRD4 interacting chromatin remodeling complex associated protein 3.24509
ZNF671 zinc finger protein 671 3.24509
CD177 CD177 molecule 3.24509
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 3.24509
MAPK12 mitogen-activated protein kinase 12 3.24509
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 3.24509
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 3.24509
LOC730098 uncharacterized LOC730098 3.24509
ALG9 ALG9, alpha-1,2-mannosyltransferase 3.24509
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 3.24509
KMT5A lysine methyltransferase 5A 3.24509
FAAH2 fatty acid amide hydrolase 2 3.24509
FBXL3 F-box and leucine-rich repeat protein 3 3.24509
SUFU suppressor of fused homolog (Drosophila) 3.24509
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 3.24509
SPATA33 spermatogenesis associated 33 3.24509
RORB RAR-related orphan receptor B 3.24509
GCLC glutamate-cysteine ligase, catalytic subunit 3.17708
CTTNBP2 cortactin binding protein 2 3.16337
C12ORF57 chromosome 12 open reading frame 57 2.87288
SLC33A2 solute carrier family 33 member 2 2.82588
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 2.82588
INTS11 integrator complex subunit 11 2.82588
ALKBH3 alkB, alkylation repair homolog 3 (E. coli) 2.82588
TWNK twinkle mtDNA helicase 2.82588
MACO1 macoilin 1 2.82588
RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 2.82588
HPSE heparanase 2.82588
SYNDIG1 synapse differentiation inducing 1 2.82588
KLHL22 kelch-like family member 22 2.82588
MAPK4 mitogen-activated protein kinase 4 2.82588
PDGFA platelet-derived growth factor alpha polypeptide 2.82588
FAM241B family with sequence similarity 241 member B 2.82588
RFLNB refilin B 2.82588
RMP64 ribonuclease MRP subunit p64 2.82588
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 2.82588
NID2 nidogen 2 (osteonidogen) 2.82588
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 2.82588
ZMIZ1 zinc finger, MIZ-type containing 1 2.82588
EEIG2 EEIG family member 2 2.82588
ZNF660-ZNF197 ZNF660-ZNF197 readthrough 2.82588
GAL3ST3 galactose-3-O-sulfotransferase 3 2.82588
ITGA7 integrin, alpha 7 2.82588
FZD2 frizzled class receptor 2 2.82588
ZC3H8 zinc finger CCCH-type containing 8 2.82588
NECAP1 NECAP endocytosis associated 1 2.82588
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 2.82588
TUBA4A tubulin, alpha 4a 2.82588
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 2.82588
ASB1 ankyrin repeat and SOCS box containing 1 2.82588
STX12 syntaxin 12 2.82588
SYNDIG1L synapse differentiation inducing 1-like 2.82588
ZNF48 zinc finger protein 48 2.82588
ZNF28 zinc finger protein 28 2.82588
FBXO17 F-box protein 17 2.81454
UNC5D unc-5 homolog D (C. elegans) 2.78177
DIXDC1 DIX domain containing 1 2.75753
SIN3B SIN3 transcription regulator family member B 2.75753
ERCC3 excision repair cross-complementation group 3 2.75753
ZNF81 zinc finger protein 81 2.75753
LMCD1 LIM and cysteine-rich domains 1 2.75753
PACS2 phosphofurin acidic cluster sorting protein 2 2.75753
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.68679
WRN Werner syndrome, RecQ helicase-like 2.66568
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) 2.66549
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.37592
LRRC8D leucine rich repeat containing 8 family, member D 2.37592
KMT5B lysine methyltransferase 5B 2.36293
RAVER1 ribonucleoprotein, PTB-binding 1 2.30029
ZNF724 zinc finger protein 724 2.30029
PDCD6 programmed cell death 6 2.30029
RTL8C retrotransposon Gag like 8C 2.30029
SLIT2 slit homolog 2 (Drosophila) 2.30029
FILIP1L filamin A interacting protein 1-like 2.30029
PCNX2 pecanex 2 2.27233
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.22571
CCDC138 coiled-coil domain containing 138 2.19153
ATP5MC2 ATP synthase membrane subunit c locus 2 2.16913
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 2.13471
RPL28 ribosomal protein L28 2.10738
ACO1 aconitase 1, soluble 2.07382
APOC1 apolipoprotein C-I 2.07382
PPT1 palmitoyl-protein thioesterase 1 2.07382
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.07382
SOX13 SRY (sex determining region Y)-box 13 2.07382
PUDP pseudouridine 5'-phosphatase 2.07382
ZNF195 zinc finger protein 195 2.07382
SCOC short coiled-coil protein 2.07382
ACAT1 acetyl-CoA acetyltransferase 1 2.07382
STX18 syntaxin 18 2.07382
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 2.07382
CRAMP1 cramped chromatin regulator homolog 1 2.07382
NANS N-acetylneuraminic acid synthase 2.07382
TMEM192 transmembrane protein 192 2.07382
NCBP1 nuclear cap binding protein subunit 1, 80kDa 2.07382
SYNE4 spectrin repeat containing, nuclear envelope family member 4 2.05066
ERLIN1 ER lipid raft associated 1 2.04262
YLPM1 YLP motif containing 1 2.01237
SEH1L SEH1-like (S. cerevisiae) 2.00329
PITPNA phosphatidylinositol transfer protein, alpha 2.00301
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 2.00301

decreased expression

Symbol Name Standardized Value
LMO4 LIM domain only 4 -3.24509
PDHB pyruvate dehydrogenase (lipoamide) beta -3.24509
COQ3 coenzyme Q3 methyltransferase -3.24509
LATS2 large tumor suppressor kinase 2 -3.24509
DSP desmoplakin -3.24509
CEP78 centrosomal protein 78kDa -3.24509
HELZ helicase with zinc finger -3.24509
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -3.24509
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -3.24509
ASCC3 activating signal cointegrator 1 complex subunit 3 -3.24509
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -3.24509
ZFP64 ZFP64 zinc finger protein -3.24509
FNIP1 folliculin interacting protein 1 -3.24509
XPC xeroderma pigmentosum, complementation group C -3.24509
MRPS23 mitochondrial ribosomal protein S23 -3.24509
NSUN6 NOP2/Sun domain family, member 6 -3.24509
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -3.24509
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -3.24509
RNF187 ring finger protein 187 -3.24509
TGIF2 TGFB-induced factor homeobox 2 -3.24509
LAS1L LAS1-like (S. cerevisiae) -3.24509
MIX23 mitochondrial matrix import factor 23 -3.24509
COL2A1 collagen, type II, alpha 1 -3.24509
EMC6 ER membrane protein complex subunit 6 -3.24509
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -3.24509
TGS1 trimethylguanosine synthase 1 -3.24509
BLM Bloom syndrome, RecQ helicase-like -3.24509
CDRT4 CMT1A duplicated region transcript 4 -3.24509
UROS uroporphyrinogen III synthase -3.24509
SCD stearoyl-CoA desaturase (delta-9-desaturase) -3.16337
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -3.04523
RAB3B RAB3B, member RAS oncogene family -2.9854
ASIC2 acid sensing (proton gated) ion channel 2 -2.9854
DMTF1 cyclin D binding myb-like transcription factor 1 -2.93933
NUP210 nucleoporin 210kDa -2.8997
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.8997
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.8997
KIF5B kinesin family member 5B -2.8997
TMX1 thioredoxin-related transmembrane protein 1 -2.8997
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -2.8997
UBE2B ubiquitin-conjugating enzyme E2B -2.8997
MRPS15 mitochondrial ribosomal protein S15 -2.79193
SLC16A9 solute carrier family 16, member 9 -2.75753
AFP alpha-fetoprotein -2.75753
SLC30A8 solute carrier family 30 (zinc transporter), member 8 -2.75753
COA6 cytochrome c oxidase assembly factor 6 -2.75753
TRAM1 translocation associated membrane protein 1 -2.75753
NR2C1 nuclear receptor subfamily 2, group C, member 1 -2.75753
RHOD ras homolog family member D -2.75753
LRRC2 leucine rich repeat containing 2 -2.75753
FGFR4 fibroblast growth factor receptor 4 -2.75753
KATNA1 katanin p60 (ATPase containing) subunit A 1 -2.75753
NT5C 5', 3'-nucleotidase, cytosolic -2.75753
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.75753
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 -2.75753
TUSC2 tumor suppressor candidate 2 -2.75753
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 -2.75753
FBN2 fibrillin 2 -2.75753
ZNF320 zinc finger protein 320 -2.75753
INTS3 integrator complex subunit 3 -2.75753
TGFBR1 transforming growth factor, beta receptor 1 -2.75753
SH3RF1 SH3 domain containing ring finger 1 -2.75753
CAMK1D calcium/calmodulin-dependent protein kinase ID -2.75753
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -2.75753
EMC4 ER membrane protein complex subunit 4 -2.75753
FBXL12 F-box and leucine-rich repeat protein 12 -2.75753
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -2.75753
LINC02983 long intergenic non-protein coding RNA 2983 -2.75753
COMMD4 COMM domain containing 4 -2.75753
GCA grancalcin, EF-hand calcium binding protein -2.75753
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) -2.75753
TEX264 testis expressed 264 -2.75753
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.75753
APH1B APH1B gamma secretase subunit -2.75753
MTMR14 myotubularin related protein 14 -2.75753
CBFB core-binding factor, beta subunit -2.75753
CLDN10 claudin 10 -2.75753
SUCLG1 succinate-CoA ligase, alpha subunit -2.75753
SHISAL2B shisa like 2B -2.75753
RIMOC1 RAB7A interacting MON1-CCZ1 complex subunit 1 -2.75753
TMEM250 transmembrane protein 250 -2.75753
TMEM268 transmembrane protein 268 -2.75753
EMSY EMSY transcriptional repressor, BRCA2 interacting -2.75753
H2AX H2A.X variant histone -2.75753
MINDY3 MINDY lysine 48 deubiquitinase 3 -2.75753
KIFBP kinesin family binding protein -2.75753
GDF11 growth differentiation factor 11 -2.75753
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 -2.75753
PRKCZ protein kinase C, zeta -2.75753
CAMK4 calcium/calmodulin-dependent protein kinase IV -2.75753
ELF1 E74-like factor 1 (ets domain transcription factor) -2.75753
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.75753
NVL nuclear VCP-like -2.75753
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 -2.75753
SPINK5 serine peptidase inhibitor, Kazal type 5 -2.75753
TMEM248 transmembrane protein 248 -2.75753
LIMA1 LIM domain and actin binding 1 -2.75753
CPPED1 calcineurin-like phosphoesterase domain containing 1 -2.75753
MYCBP MYC binding protein -2.75753
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) -2.75753
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.75753
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) -2.75753
IFT22 intraflagellar transport 22 -2.75753
CDC7 cell division cycle 7 -2.75753
ZDHHC16 zinc finger, DHHC-type containing 16 -2.75753
C16ORF95 chromosome 16 open reading frame 95 -2.75753
PMPCB peptidase (mitochondrial processing) beta -2.75753
IL17RC interleukin 17 receptor C -2.75753
ACOX1 acyl-CoA oxidase 1, palmitoyl -2.75753
RBSN rabenosyn, RAB effector -2.75753
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -2.75753
MAP1S microtubule-associated protein 1S -2.75753
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -2.75753
TWSG1 twisted gastrulation BMP signaling modulator 1 -2.75753
IP6K2 inositol hexakisphosphate kinase 2 -2.75753
NGDN neuroguidin, EIF4E binding protein -2.75753
MSTO1 misato 1, mitochondrial distribution and morphology regulator -2.75753
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -2.75753
NSUN5 NOP2/Sun domain family, member 5 -2.75753
MBOAT7 membrane bound O-acyltransferase domain containing 7 -2.75753
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 -2.75753
LRRC40 leucine rich repeat containing 40 -2.75753
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -2.75753
KIAA1549 KIAA1549 -2.75753
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.75753
MCTP1 multiple C2 domains, transmembrane 1 -2.75753
SYT2 synaptotagmin II -2.75753
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.75753
ZFP91 ZFP91 zinc finger protein -2.75753
THOP1 thimet oligopeptidase 1 -2.75753
KCTD10 potassium channel tetramerization domain containing 10 -2.75753
AGPS alkylglycerone phosphate synthase -2.75753
HEATR5B HEAT repeat containing 5B -2.75753
GPC6 glypican 6 -2.75753
ERCC1 excision repair cross-complementation group 1 -2.75753
GRWD1 glutamate-rich WD repeat containing 1 -2.75753
ZFPM1 zinc finger protein, FOG family member 1 -2.75753
PHYH phytanoyl-CoA 2-hydroxylase -2.75753
PLA2R1 phospholipase A2 receptor 1, 180kDa -2.75753
PCNT pericentrin -2.75753
RGS6 regulator of G-protein signaling 6 -2.75753
AHDC1 AT hook, DNA binding motif, containing 1 -2.75753
IPMK inositol polyphosphate multikinase -2.75753
FBXO46 F-box protein 46 -2.75753
ARMC10 armadillo repeat containing 10 -2.742
SAV1 salvador family WW domain containing protein 1 -2.742
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.742
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -2.742
RAD54L2 RAD54-like 2 (S. cerevisiae) -2.742
USP6NL USP6 N-terminal like -2.742
MRPS17 mitochondrial ribosomal protein S17 -2.742
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.69596
KIF1B kinesin family member 1B -2.68587
MDK midkine (neurite growth-promoting factor 2) -2.56359
GRIK2 glutamate receptor, ionotropic, kainate 2 -2.55459
ANAPC15 anaphase promoting complex subunit 15 -2.55459
ACLY ATP citrate lyase -2.5545
TOP2B topoisomerase (DNA) II beta 180kDa -2.53853
KALRN kalirin, RhoGEF kinase -2.50363
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -2.50363
ECH1 enoyl CoA hydratase 1, peroxisomal -2.50363
IPO8 importin 8 -2.50107
SIL1 SIL1 nucleotide exchange factor -2.48702
RNF130 ring finger protein 130 -2.36293
PPP6C protein phosphatase 6, catalytic subunit -2.36293
SFT2D1 SFT2 domain containing 1 -2.36293
ARHGAP17 Rho GTPase activating protein 17 -2.36293
GRK3 G protein-coupled receptor kinase 3 -2.30029
UBXN7 UBX domain protein 7 -2.30029
RESF1 retroelement silencing factor 1 -2.27233
SGO1 shugoshin 1 -2.27233
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.27233
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -2.27233
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -2.27233
CD320 CD320 molecule -2.27233
TMEM42 transmembrane protein 42 -2.27233
PANK1 pantothenate kinase 1 -2.27233
HPS5 Hermansky-Pudlak syndrome 5 -2.27233
CDCA3 cell division cycle associated 3 -2.27233
SLC38A9 solute carrier family 38, member 9 -2.27233
GINS4 GINS complex subunit 4 (Sld5 homolog) -2.27233
TTC3 tetratricopeptide repeat domain 3 -2.27233
BAHD1 bromo adjacent homology domain containing 1 -2.27233
TBC1D4 TBC1 domain family, member 4 -2.27233
DAXX death-domain associated protein -2.27233
SEC31A SEC31 homolog A (S. cerevisiae) -2.27233
OGFRL1 opioid growth factor receptor-like 1 -2.27233
LIG3 ligase III, DNA, ATP-dependent -2.27233
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.27233
RUFY3 RUN and FYVE domain containing 3 -2.27233
GLB1 galactosidase, beta 1 -2.27233
C5ORF15 chromosome 5 open reading frame 15 -2.27233
IFT52 intraflagellar transport 52 -2.27233
LIN52 lin-52 DREAM MuvB core complex component -2.25281
CSNK2B casein kinase 2, beta polypeptide -2.25136
AUH AU RNA binding protein/enoyl-CoA hydratase -2.22016
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -2.21406
RSL1D1 ribosomal L1 domain containing 1 -2.17501
TLE5 TLE family member 5, transcriptional modulator -2.07382
ZNF613 zinc finger protein 613 -2.07382
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.07382
SETD3 SET domain containing 3 -2.07382
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.07382
HACL1 2-hydroxyacyl-CoA lyase 1 -2.07382
PCED1B PC-esterase domain containing 1B -2.07382
YJU2B YJU2 splicing factor homolog B -2.07382
MTRES1 mitochondrial transcription rescue factor 1 -2.07382
EFTUD2 elongation factor Tu GTP binding domain containing 2 -2.07382
POGK pogo transposable element with KRAB domain -2.07382
LAMP1 lysosomal-associated membrane protein 1 -2.07382
RBIS ribosomal biogenesis factor -2.07382
RCC1 regulator of chromosome condensation 1 -2.07382
RBM12B RNA binding motif protein 12B -2.07382
NUP58 nucleoporin 58 -2.07382
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component -2.07382
ZFYVE16 zinc finger, FYVE domain containing 16 -2.07382
RNASEH2B ribonuclease H2, subunit B -2.07382
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -2.07382
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.07382
DEDD death effector domain containing -2.07382
RSRP1 arginine/serine-rich protein 1 -2.07382
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -2.07382
OLFML3 olfactomedin-like 3 -2.07382
IGFBPL1 insulin-like growth factor binding protein-like 1 -2.07382
TRIM59 tripartite motif containing 59 -2.07382
BCL10 B-cell CLL/lymphoma 10 -2.07382
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -2.07382
CHRAC1 chromatin accessibility complex 1 -2.07382
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -2.07382
SMDT1 single-pass membrane protein with aspartate-rich tail 1 -2.07382
POU6F2 POU class 6 homeobox 2 -2.07382
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -2.07382
FGFR1OP2 FGFR1 oncogene partner 2 -2.07382
SIKE1 suppressor of IKBKE 1 -2.07382
FAHD1 fumarylacetoacetate hydrolase domain containing 1 -2.07382
PRKD2 protein kinase D2 -2.07382
DYM dymeclin -2.06984
BEX3 brain expressed X-linked 3 -2.06276
FHIP1A FHF complex subunit HOOK interacting protein 1A -2.00301
KLHDC4 kelch domain containing 4 -2.00301
GPR160 G protein-coupled receptor 160 -2.00301
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.00301
ARG2 arginase 2 -2.00301
TRIOBP TRIO and F-actin binding protein -2.00301
UBE2J2 ubiquitin-conjugating enzyme E2, J2 -2.00301
CREM cAMP responsive element modulator -2.00301
RPF2 ribosome production factor 2 homolog (S. cerevisiae) -2.00301
INTU inturned planar cell polarity protein -2.00301
ELK1 ELK1, member of ETS oncogene family -2.00301
METTL23 methyltransferase like 23 -2.00301
ACSL4 acyl-CoA synthetase long-chain family member 4 -2.00301
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -2.00301
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -2.00301
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.00301
ZCCHC14 zinc finger, CCHC domain containing 14 -2.00301
RBBP6 retinoblastoma binding protein 6 -2.00301
SMIM19 small integral membrane protein 19 -2.00301