WEE1 Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description WEE1 G2 checkpoint kinase|This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7465)
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100 substrates of the kinase WEE1 from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 99.96
PINK1 PTEN induced putative kinase 1 99.89
SMG8 SMG8 nonsense mediated mRNA decay factor 99.85
FBXO11 F-box protein 11 99.8
EGR1 early growth response 1 99.71
SPANXN2 SPANX family, member N2 99.69
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 99.59
WWP2 WW domain containing E3 ubiquitin protein ligase 2 99.52
TNNI3 troponin I type 3 (cardiac) 99.52
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 99.5
TMEM132A transmembrane protein 132A 99.48
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 99.45
RPL36AL ribosomal protein L36a-like 99.34
LRPPRC leucine-rich pentatricopeptide repeat containing 99.32
ZFPL1 zinc finger protein-like 1 99.26
MIS18BP1 MIS18 binding protein 1 99.25
JARID2 jumonji, AT rich interactive domain 2 99.23
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 99.13
ADAM15 ADAM metallopeptidase domain 15 99.13
HPSE heparanase 99.1
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 99.1
PHF6 PHD finger protein 6 99.02
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 99.01
ANPEP alanyl (membrane) aminopeptidase 98.91
RDX radixin 98.84
FKBP8 FK506 binding protein 8, 38kDa 98.75
LYST lysosomal trafficking regulator 98.71
PEX1 peroxisomal biogenesis factor 1 98.64
MERTK MER proto-oncogene, tyrosine kinase 98.51
LHX3 LIM homeobox 3 98.49
SNAP23 synaptosomal-associated protein, 23kDa 98.4
SNU13 small nuclear ribonucleoprotein 13 98.29
PRMT3 protein arginine methyltransferase 3 98.23
MMP14 matrix metallopeptidase 14 (membrane-inserted) 98.12
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 98.12
PFKM phosphofructokinase, muscle 98.1
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 98.09
INTS12 integrator complex subunit 12 98.09
TBC1D3C TBC1 domain family, member 3C 98.01
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 97.97
YBX3 Y box binding protein 3 97.85
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 97.83
MYD88 myeloid differentiation primary response 88 97.81
ST20-MTHFS ST20-MTHFS readthrough 97.79
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 97.79
ZC3HAV1 zinc finger CCCH-type, antiviral 1 97.62
TRA2A transformer 2 alpha homolog (Drosophila) 97.53
PLD2 phospholipase D2 97.39
SARM1 sterile alpha and TIR motif containing 1 97.37
GPATCH8 G patch domain containing 8 97.35
ITSN1 intersectin 1 (SH3 domain protein) 97.33
KIF26A kinesin family member 26A 97.31
AURKA aurora kinase A 97.31
SRSF10 serine/arginine-rich splicing factor 10 97.275
CCT8 chaperonin containing TCP1, subunit 8 (theta) 97.27
THRB thyroid hormone receptor, beta 97.27
TAOK3 TAO kinase 3 97.185
GULP1 GULP, engulfment adaptor PTB domain containing 1 97.18
CSNK2A2 casein kinase 2, alpha prime polypeptide 97.09
AHCY adenosylhomocysteinase 96.93
FLI1 Fli-1 proto-oncogene, ETS transcription factor 96.87
KIF20A kinesin family member 20A 96.74
PADI2 peptidyl arginine deiminase, type II 96.7
RFTN1 raftlin, lipid raft linker 1 96.69
GOPC golgi-associated PDZ and coiled-coil motif containing 96.58
CD37 CD37 molecule 96.5
POLR1G RNA polymerase I subunit G 96.43
KLHDC3 kelch domain containing 3 96.35
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 96.34
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 96.23
FBP1 fructose-1,6-bisphosphatase 1 96.19
SLA Src-like-adaptor 96.13
LMBR1 limb development membrane protein 1 96.08
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 96.06
UBE2E2 ubiquitin-conjugating enzyme E2E 2 96.04
UBE2E3 ubiquitin-conjugating enzyme E2E 3 96.04
UBE2E1 ubiquitin-conjugating enzyme E2E 1 96.04
IRF1 interferon regulatory factor 1 95.84
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 95.69
RBM25 RNA binding motif protein 25 95.69
PCYOX1 prenylcysteine oxidase 1 95.67
ITGB5 integrin, beta 5 95.6
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 95.51
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 95.51
NAGK N-acetylglucosamine kinase 95.45
CD274 CD274 molecule 95.42
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 95.33
EEF1B2 eukaryotic translation elongation factor 1 beta 2 95.32
ANXA8L1 annexin A8-like 1 95.29
ANXA8 annexin A8 95.29
TENT4A terminal nucleotidyltransferase 4A 95.21
SSTR2 somatostatin receptor 2 95.19
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 95.16
PHB2 prohibitin 2 95.11
KANK2 KN motif and ankyrin repeat domains 2 95.08
FCHO1 FCH domain only 1 95.07
FZD2 frizzled class receptor 2 95.07
ICAM1 intercellular adhesion molecule 1 95.065
CEP55 centrosomal protein 55kDa 94.84
ADA adenosine deaminase 94.77