WEE1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description WEE1 G2 checkpoint kinase|This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7465)
External Link https://ncbi.nlm.nih.gov/gene/7465
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Genes

498 genes differentially expressed following the WEE1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HIST1H2AC histone cluster 1, H2ac 0.0101555
KRT19 keratin 19, type I 0.00974155
FTH1 ferritin, heavy polypeptide 1 0.00920793
HIST1H2BD histone cluster 1, H2bd 0.00885824
CXCL8 chemokine (C-X-C motif) ligand 8 0.00878753
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00875043
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00873169
LCN2 lipocalin 2 0.00861296
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00846544
KRT7 keratin 7, type II 0.00843869
XIC X chromosome inactivation center 0.00824943
G0S2 G0/G1 switch 2 0.00793732
HSPA1A heat shock 70kDa protein 1A 0.00783239
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0075573
MAP7 microtubule-associated protein 7 0.00747914
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00727921
CYBA cytochrome b-245, alpha polypeptide 0.00720617
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00711318
KLK11 kallikrein-related peptidase 11 0.00710674
TPSAB1 tryptase alpha/beta 1 0.00699811
SLPI secretory leukocyte peptidase inhibitor 0.00691797
BLNK B-cell linker 0.00687128
EIF5A eukaryotic translation initiation factor 5A 0.00664973
BTG1 B-cell translocation gene 1, anti-proliferative 0.00664796
IFI6 interferon, alpha-inducible protein 6 0.00664379
GAS6 growth arrest-specific 6 0.00658037
TTC39A tetratricopeptide repeat domain 39A 0.00650726
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00636146
CTSZ cathepsin Z 0.00624114
SIK1 salt-inducible kinase 1 0.0062339
TPD52L1 tumor protein D52-like 1 0.00622157
PON2 paraoxonase 2 0.00618456
CD9 CD9 molecule 0.00609022
TRIM29 tripartite motif containing 29 0.0060674
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00604394
TUFT1 tuftelin 1 0.00602134
HIST1H2BK histone cluster 1, H2bk 0.0060198
PERP PERP, TP53 apoptosis effector 0.00591367
IPO13 importin 13 0.00582432
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00579601
TFPI2 tissue factor pathway inhibitor 2 0.00576687
TOB1 transducer of ERBB2, 1 0.00576261
GADD45A growth arrest and DNA-damage-inducible, alpha 0.0057499
CYBB cytochrome b-245, beta polypeptide 0.00573937
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00569911
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00566426
AOC1 amine oxidase, copper containing 1 0.00560479
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00560184
GPNMB glycoprotein (transmembrane) nmb 0.00558542
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0055514
WASL Wiskott-Aldrich syndrome-like 0.00549666
ALOX5 arachidonate 5-lipoxygenase 0.00548957
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00537639
IER5 immediate early response 5 0.0053102
BCL3 B-cell CLL/lymphoma 3 0.00528853
H1-2 H1.2 linker histone, cluster member 0.00528299
IRS1 insulin receptor substrate 1 0.00528055
OPN3 opsin 3 0.00527636
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.00525676
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00525242
DSP desmoplakin 0.00524077
CD14 CD14 molecule 0.0052109
TPBG trophoblast glycoprotein 0.00520134
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00519224
KLF5 Kruppel-like factor 5 (intestinal) 0.00518836
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.00516687
EMP3 epithelial membrane protein 3 0.00516323
SFRP4 secreted frizzled-related protein 4 0.00514916
MYRF myelin regulatory factor 0.00511294
S100A8 S100 calcium binding protein A8 0.00510555
INHBA inhibin, beta A 0.00506677
RND3 Rho family GTPase 3 0.00501427
QPCT glutaminyl-peptide cyclotransferase 0.00500673
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00500417
IGFBP5 insulin-like growth factor binding protein 5 0.00497421
NDRG1 N-myc downstream regulated 1 0.00495899
ANKRD11 ankyrin repeat domain 11 0.00493891
NUTF2 nuclear transport factor 2 0.00489773
PTK2B protein tyrosine kinase 2 beta 0.0048947
EREG epiregulin 0.00489053
CAPN1 calpain 1, (mu/I) large subunit 0.00485725
KLK10 kallikrein-related peptidase 10 0.00484819
PLAAT3 phospholipase A and acyltransferase 3 0.00482931
ASRGL1 asparaginase like 1 0.00482129
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.00481855
MAPT microtubule-associated protein tau 0.00479965
GRB14 growth factor receptor-bound protein 14 0.0047768
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0047736
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00476532
STC2 stanniocalcin 2 0.0047334
BLVRB biliverdin reductase B 0.00472971
MFAP3L microfibrillar-associated protein 3-like 0.00472967
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00472412
HMOX1 heme oxygenase 1 0.00471668
PHLDA3 pleckstrin homology-like domain, family A, member 3 0.00471604
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00470975
SCGB2A1 secretoglobin, family 2A, member 1 0.00469795
MUC1 mucin 1, cell surface associated 0.00469456
S100A11 S100 calcium binding protein A11 0.00468285
TRAPPC6A trafficking protein particle complex 6A 0.00466754
FGB fibrinogen beta chain 0.004666
SCGB1D2 secretoglobin, family 1D, member 2 0.00465715
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00464465
HSPB1 heat shock 27kDa protein 1 0.00463847
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.00462687
ATF5 activating transcription factor 5 0.00462193
ELANE elastase, neutrophil expressed 0.00461751
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 0.0045944
S100A6 S100 calcium binding protein A6 0.00458926
CRABP2 cellular retinoic acid binding protein 2 0.0045849
CDC42SE1 CDC42 small effector 1 0.0045763
TM7SF2 transmembrane 7 superfamily member 2 0.00457351
TGM2 transglutaminase 2 0.00457278
SIRPA signal-regulatory protein alpha 0.00456903
COMP cartilage oligomeric matrix protein 0.00456398
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00455741
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00455271
SATB2 SATB homeobox 2 0.00453993
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00453809
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.00453539
TUBA4A tubulin, alpha 4a 0.00453121
NAMPT nicotinamide phosphoribosyltransferase 0.00451204
FGG fibrinogen gamma chain 0.00449568
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00446647
S100A10 S100 calcium binding protein A10 0.00446088
CPM carboxypeptidase M 0.00445774
TSPO translocator protein (18kDa) 0.00444063
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00441704
CDA cytidine deaminase 0.00441225
DEF8 differentially expressed in FDCP 8 homolog (mouse) 0.00440728
TBCB tubulin folding cofactor B 0.00439635
TP53I3 tumor protein p53 inducible protein 3 0.00438823
CUEDC1 CUE domain containing 1 0.00435238
ANXA5 annexin A5 0.00435011
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.00434814
GLA galactosidase, alpha 0.00433104
NRIP3 nuclear receptor interacting protein 3 0.00432736
LSR lipolysis stimulated lipoprotein receptor 0.00431947
RHOB ras homolog family member B 0.00431821
NADSYN1 NAD synthetase 1 0.0043147
UBE2S ubiquitin-conjugating enzyme E2S 0.0043126
TYROBP TYRO protein tyrosine kinase binding protein 0.0043126
CLEC11A C-type lectin domain family 11, member A 0.00429707
ABHD4 abhydrolase domain containing 4 0.00428261
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00427514
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00426035
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00425151
SERINC5 serine incorporator 5 0.00424284
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00424238
PRODH proline dehydrogenase (oxidase) 1 0.00423327
BRD2 bromodomain containing 2 0.00422901
RNH1 ribonuclease/angiogenin inhibitor 1 0.00421905
RBM34 RNA binding motif protein 34 0.00420239
GRK2 G protein-coupled receptor kinase 2 0.00419794
MT1X metallothionein 1X 0.00417789
NEFH neurofilament, heavy polypeptide 0.00417675
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00415621
HGD homogentisate 1,2-dioxygenase 0.00415129
NAXD NAD(P)HX dehydratase 0.00413251
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.00413152
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00413139
ZNF423 zinc finger protein 423 0.00412537
BCAS1 breast carcinoma amplified sequence 1 0.00411791
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00411034
NCF2 neutrophil cytosolic factor 2 0.00406766
PDGFA platelet-derived growth factor alpha polypeptide 0.00405888
TMEM110 transmembrane protein 110 0.00405855
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00405305
LAMP5 lysosomal-associated membrane protein family, member 5 0.00405155
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00403112
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00402878
H2AFV H2A histone family, member V 0.00402134
AHNAK AHNAK nucleoprotein 0.00401824
LTBP2 latent transforming growth factor beta binding protein 2 0.00401784
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00401475
PHF1 PHD finger protein 1 0.00399635
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00399288
YPEL5 yippee-like 5 (Drosophila) 0.00399024
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00397414
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.00397285
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00396853
AQP3 aquaporin 3 (Gill blood group) 0.00396556
RTL8C retrotransposon Gag like 8C 0.0039491
SCPEP1 serine carboxypeptidase 1 0.00393502
CRISP3 cysteine-rich secretory protein 3 0.0039347
KIF1A kinesin family member 1A 0.0039345
KLHL24 kelch-like family member 24 0.0039324
NBPF10 neuroblastoma breakpoint family, member 10 0.00392373
HMG20B high mobility group 20B 0.00391384
SCGB2A2 secretoglobin, family 2A, member 2 0.00390779
ACKR3 atypical chemokine receptor 3 0.00389761
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00389497
GADD45B growth arrest and DNA-damage-inducible, beta 0.00389461
LIN37 lin-37 DREAM MuvB core complex component 0.00389103
PFN2 profilin 2 0.00388778
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00388615
DDA1 DET1 and DDB1 associated 1 0.00388133
EMP1 epithelial membrane protein 1 0.00387686
CDC16 cell division cycle 16 0.00386914
AZU1 azurocidin 1 0.00385564
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00385313
GRN granulin 0.00383704
RSRP1 arginine/serine-rich protein 1 0.0038361
CD177 CD177 molecule 0.00383053
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.00382183
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.0038215
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00381857
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.00381837
TMEM147 transmembrane protein 147 0.00381684
CCL13 chemokine (C-C motif) ligand 13 0.00381159
KRT14 keratin 14, type I 0.00379889
BPGM 2,3-bisphosphoglycerate mutase 0.00379797
LOC105375355 uroplakin-3b 0.00377986
TRIP6 thyroid hormone receptor interactor 6 0.00377658
ESRP1 epithelial splicing regulatory protein 1 0.00374614
RRAGC Ras-related GTP binding C 0.0037292
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00372906
NXF1 nuclear RNA export factor 1 0.00372085
PIAS3 protein inhibitor of activated STAT, 3 0.00371368
S100A9 S100 calcium binding protein A9 0.00371184
UBXN1 UBX domain protein 1 0.00370859
LAMC2 laminin, gamma 2 0.00370832
GAB2 GRB2-associated binding protein 2 0.0036934
KIFC3 kinesin family member C3 0.0036892
RAP2B RAP2B, member of RAS oncogene family 0.00368823
KRT17 keratin 17, type I 0.00368819
BGN biglycan 0.00368658
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.00367261
SH3YL1 SH3 and SYLF domain containing 1 0.00367153
VSIG4 V-set and immunoglobulin domain containing 4 0.00365905
SRGN serglycin 0.00365793
RHOD ras homolog family member D 0.00365327
NCF1C neutrophil cytosolic factor 1C pseudogene 0.0036523
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.00365142
AGRN agrin 0.00363862
SULF1 sulfatase 1 0.00363717
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00363013
GALC galactosylceramidase 0.00362986
EIF5 eukaryotic translation initiation factor 5 0.00362326
REXO2 RNA exonuclease 2 0.00361694
EHF ets homologous factor 0.00361604
TSC22D4 TSC22 domain family, member 4 0.00361364
MCM2 minichromosome maintenance complex component 2 0.00360081
SFN stratifin 0.00359759
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 0.00359397
S100A14 S100 calcium binding protein A14 0.00358979
SQSTM1 sequestosome 1 0.00358898
S100A12 S100 calcium binding protein A12 0.00358804
CXCL3 chemokine (C-X-C motif) ligand 3 0.00357468

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0139782
DLK1 delta-like 1 homolog (Drosophila) -0.0103258
NIBAN1 niban apoptosis regulator 1 -0.0102949
NID1 nidogen 1 -0.00917407
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00878026
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00875722
NELL2 NEL-like 2 (chicken) -0.00850588
NES nestin -0.00827264
FGFR1 fibroblast growth factor receptor 1 -0.00818339
SFRP1 secreted frizzled-related protein 1 -0.00807485
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00797934
MGP matrix Gla protein -0.00789207
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00749083
VWF von Willebrand factor -0.0074523
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00727537
CLU clusterin -0.00720735
ZEB1 zinc finger E-box binding homeobox 1 -0.00710155
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00696517
GIMAP6 GTPase, IMAP family member 6 -0.00686274
PRDX2 peroxiredoxin 2 -0.00679689
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.00665543
CCNF cyclin F -0.00662101
SYNM synemin, intermediate filament protein -0.00659632
CD93 CD93 molecule -0.00649897
GNAS GNAS complex locus -0.00648449
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00638467
KDM5D lysine (K)-specific demethylase 5D -0.00632275
GPC3 glypican 3 -0.00630286
PCLAF PCNA clamp associated factor -0.00630004
CBR3 carbonyl reductase 3 -0.0062532
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00621363
LAMA4 laminin, alpha 4 -0.00605816
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00604863
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00597478
PDE4B phosphodiesterase 4B, cAMP-specific -0.00597168
RRM1 ribonucleotide reductase M1 -0.00595517
CHN1 chimerin 1 -0.00591334
TRIM14 tripartite motif containing 14 -0.00590403
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.00588845
C7 complement component 7 -0.00587195
NRN1 neuritin 1 -0.00585163
PTK2 protein tyrosine kinase 2 -0.00582567
A2M alpha-2-macroglobulin -0.0057554
MELK maternal embryonic leucine zipper kinase -0.00571942
NUP85 nucleoporin 85kDa -0.00570898
COQ8A coenzyme Q8A -0.00561785
ITM2A integral membrane protein 2A -0.00560945
MCM5 minichromosome maintenance complex component 5 -0.0056021
DPYSL3 dihydropyrimidinase-like 3 -0.00558912
CRYBG1 crystallin beta-gamma domain containing 1 -0.00556411
RPIA ribose 5-phosphate isomerase A -0.00555179
BST2 bone marrow stromal cell antigen 2 -0.00553007
CCL19 chemokine (C-C motif) ligand 19 -0.00552316
FABP7 fatty acid binding protein 7, brain -0.00548558
DCLRE1C DNA cross-link repair 1C -0.0054715
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00546512
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00546201
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -0.00544004
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00543938
MAOB monoamine oxidase B -0.0054303
CDC7 cell division cycle 7 -0.00540837
FBXO11 F-box protein 11 -0.00540534
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00538456
EGR2 early growth response 2 -0.0053711
ATP9A ATPase, class II, type 9A -0.0053658
WEE1 WEE1 G2 checkpoint kinase -0.00536166
ADGRG2 adhesion G protein-coupled receptor G2 -0.00534627
SDC2 syndecan 2 -0.00534066
BIRC5 baculoviral IAP repeat containing 5 -0.00528621
ADCY3 adenylate cyclase 3 -0.00528469
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00526313
CCNE2 cyclin E2 -0.00526145
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00524781
CD99 CD99 molecule -0.0052066
MCM6 minichromosome maintenance complex component 6 -0.00519334
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00518417
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00515091
OXCT1 3-oxoacid CoA transferase 1 -0.00514548
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00514463
IFI44 interferon-induced protein 44 -0.00512414
MYH11 myosin, heavy chain 11, smooth muscle -0.00512369
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00507868
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.0050755
SVIL supervillin -0.00506596
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00505613
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.00505033
CALML5 calmodulin-like 5 -0.00503347
ZNF395 zinc finger protein 395 -0.00502822
DCLK1 doublecortin-like kinase 1 -0.00499014
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00498352
DEK DEK proto-oncogene -0.00496274
ETV1 ets variant 1 -0.00493356
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00492151
MCAM melanoma cell adhesion molecule -0.0048937
ITK IL2-inducible T-cell kinase -0.00488889
PTN pleiotrophin -0.00488198
GIMAP5 GTPase, IMAP family member 5 -0.00485234
SRPX sushi-repeat containing protein, X-linked -0.00483601
CTSW cathepsin W -0.0048315
C1ORF115 chromosome 1 open reading frame 115 -0.00482026
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -0.00481987
KIF5C kinesin family member 5C -0.00481431
GZMK granzyme K (granzyme 3; tryptase II) -0.0048062
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00480307
RPN2 ribophorin II -0.00479959
NFIB nuclear factor I/B -0.00479451
IFITM3 interferon induced transmembrane protein 3 -0.00478578
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.00477771
GIMAP4 GTPase, IMAP family member 4 -0.00476253
F2R coagulation factor II (thrombin) receptor -0.00472351
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00470037
TSPAN7 tetraspanin 7 -0.0046802
HDAC1 histone deacetylase 1 -0.0046764
FNBP1 formin binding protein 1 -0.00467169
MTARC1 mitochondrial amidoxime reducing component 1 -0.00467124
RMI1 RecQ mediated genome instability 1 -0.0046711
CCL21 chemokine (C-C motif) ligand 21 -0.00466597
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00464097
SET SET nuclear proto-oncogene -0.00463386
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00461745
CD2 CD2 molecule -0.00461529
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -0.00459121
CAND1 cullin-associated and neddylation-dissociated 1 -0.00458714
BMP4 bone morphogenetic protein 4 -0.00458349
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.0045699
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.0045695
RAD23B RAD23 homolog B (S. cerevisiae) -0.00454165
SPARCL1 SPARC-like 1 (hevin) -0.00453194
KLHL3 kelch-like family member 3 -0.00451845
PLAGL2 pleiomorphic adenoma gene-like 2 -0.00451428
ADAM19 ADAM metallopeptidase domain 19 -0.00450838
PLVAP plasmalemma vesicle associated protein -0.00450657
CDK1 cyclin-dependent kinase 1 -0.00449991
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00448398
ASF1B anti-silencing function 1B histone chaperone -0.00447944
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00444044
CALD1 caldesmon 1 -0.00443476
ANPEP alanyl (membrane) aminopeptidase -0.00443302
TUBB2B tubulin, beta 2B class IIb -0.00442692
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.00441305
TYMS thymidylate synthetase -0.00441298
RFC2 replication factor C (activator 1) 2, 40kDa -0.00441149
PHYH phytanoyl-CoA 2-hydroxylase -0.00440932
LIMA1 LIM domain and actin binding 1 -0.00439878
GARS1 glycyl-tRNA synthetase 1 -0.00439642
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00439345
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00438324
FZD6 frizzled class receptor 6 -0.00438146
RRM2 ribonucleotide reductase M2 -0.00437547
LPP LIM domain containing preferred translocation partner in lipoma -0.00436894
NCOA4 nuclear receptor coactivator 4 -0.00436336
CD48 CD48 molecule -0.00434904
FAR2 fatty acyl CoA reductase 2 -0.00434305
MACF1 microtubule-actin crosslinking factor 1 -0.00433529
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0043347
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.00432998
CD96 CD96 molecule -0.004323
FABP4 fatty acid binding protein 4, adipocyte -0.0043127
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00430536
WWTR1 WW domain containing transcription regulator 1 -0.00430455
MGST2 microsomal glutathione S-transferase 2 -0.00429597
UXT ubiquitously-expressed, prefoldin-like chaperone -0.0042599
PRKCH protein kinase C, eta -0.00425783
SORBS1 sorbin and SH3 domain containing 1 -0.00425094
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00424302
GBP1 guanylate binding protein 1, interferon-inducible -0.00423276
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00423013
PTGIS prostaglandin I2 (prostacyclin) synthase -0.0042264
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -0.00422621
DNM1L dynamin 1-like -0.00422349
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.00422
CALCRL calcitonin receptor-like -0.00421824
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00420861
GAL galanin/GMAP prepropeptide -0.00420388
RFTN1 raftlin, lipid raft linker 1 -0.00420032
TMEM131L transmembrane 131 like -0.00419477
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00419231
RCAN2 regulator of calcineurin 2 -0.00419106
LMNB1 lamin B1 -0.00419006
FABP1 fatty acid binding protein 1, liver -0.00418648
CNR1 cannabinoid receptor 1 (brain) -0.00418603
CPVL carboxypeptidase, vitellogenic-like -0.00418217
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00418203
CCL5 chemokine (C-C motif) ligand 5 -0.00418136
TGFBR3 transforming growth factor, beta receptor III -0.00417631
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00416962
IFI44L interferon-induced protein 44-like -0.00416847
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.00416298
MXRA7 matrix-remodelling associated 7 -0.00415857
NFE2L3 nuclear factor, erythroid 2-like 3 -0.0041538
PSIP1 PC4 and SFRS1 interacting protein 1 -0.00414631
IFT52 intraflagellar transport 52 -0.00413575
RGS5 regulator of G-protein signaling 5 -0.00413499
COL4A1 collagen, type IV, alpha 1 -0.00412343
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00411605
UBB ubiquitin B -0.00411322
RTN1 reticulon 1 -0.00410446
TACC1 transforming, acidic coiled-coil containing protein 1 -0.00409388
DES desmin -0.00408797
FILIP1L filamin A interacting protein 1-like -0.00407786
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.00406732
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00405525
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00404991
MCM10 minichromosome maintenance complex component 10 -0.0040493
ADGRE1 adhesion G protein-coupled receptor E1 -0.0040484
ELOVL6 ELOVL fatty acid elongase 6 -0.00404503
PLN phospholamban -0.00400147
EMCN endomucin -0.00399988
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.00399745
CA9 carbonic anhydrase IX -0.00399518
AQP1 aquaporin 1 (Colton blood group) -0.00399512
BLMH bleomycin hydrolase -0.00398807
CFI complement factor I -0.00398773
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00397556
GOLT1B golgi transport 1B -0.00396137
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00396006
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00395386
CAVIN2 caveolae associated protein 2 -0.00395126
DMD dystrophin -0.00392653
COL15A1 collagen, type XV, alpha 1 -0.00392582
ATAD2 ATPase family, AAA domain containing 2 -0.00392056
SLC2A4RG SLC2A4 regulator -0.00391485
ADAMDEC1 ADAM-like, decysin 1 -0.00391275
DPYD dihydropyrimidine dehydrogenase -0.00390484
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00390146
SOX11 SRY (sex determining region Y)-box 11 -0.00389749
CCNI cyclin I -0.00389329
RPA3 replication protein A3, 14kDa -0.00389073
IFITM1 interferon induced transmembrane protein 1 -0.00388496
FOXM1 forkhead box M1 -0.00387967
SPART spartin -0.00387442
ERGIC2 ERGIC and golgi 2 -0.00387154
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00387072
MSH2 mutS homolog 2 -0.00386108
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.00386057
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00386022
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00385172
IL7R interleukin 7 receptor -0.0038507
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0038413
PHACTR2 phosphatase and actin regulator 2 -0.00383936
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00383774
STON1 stonin 1 -0.003837
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00381188
MSH6 mutS homolog 6 -0.00380828
SELL selectin L -0.00380252
ALB albumin -0.00380216
GPR171 G protein-coupled receptor 171 -0.00379747
LAPTM4B lysosomal protein transmembrane 4 beta -0.00379586
CCNA2 cyclin A2 -0.00379179