WEE1_druginhibition_307_GSE38972 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38972
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Genes

600 genes differentially expressed following the WEE1_druginhibition_307_GSE38972 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
CBX6 chromobox homolog 6 3.49552
ADD3 adducin 3 (gamma) 3.42596
FAM200B family with sequence similarity 200, member B 3.37035
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.29275
ANXA4 annexin A4 3.26556
MACF1 microtubule-actin crosslinking factor 1 3.24148
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 3.22673
AP2B1 adaptor-related protein complex 2, beta 1 subunit 3.2177
UBC ubiquitin C 3.11832
SOCS2 suppressor of cytokine signaling 2 2.96858
LETMD1 LETM1 domain containing 1 2.95187
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.92681
EIF3E eukaryotic translation initiation factor 3, subunit E 2.92544
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 2.9233
MEF2A myocyte enhancer factor 2A 2.83276
TLCD2 TLC domain containing 2 2.74944
TEN1 TEN1 CST complex subunit 2.72556
HLA-F major histocompatibility complex, class I, F 2.72391
HINT2 histidine triad nucleotide binding protein 2 2.64317
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 2.63744
FBXL20 F-box and leucine-rich repeat protein 20 2.54177
UBXN7 UBX domain protein 7 2.52797
TARBP1 TAR (HIV-1) RNA binding protein 1 2.47246
TMSB10 thymosin beta 10 2.45805
CCNI cyclin I 2.45798
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 2.45117
FAM53C family with sequence similarity 53, member C 2.43509
ANKRD11 ankyrin repeat domain 11 2.42886
RAD17 RAD17 homolog (S. pombe) 2.41764
FADS3 fatty acid desaturase 3 2.40232
IK IK cytokine, down-regulator of HLA II 2.39036
QARS glutaminyl-tRNA synthetase 2.38813
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.36639
RTN4 reticulon 4 2.35098
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.35077
PGLS 6-phosphogluconolactonase 2.35049
VRK2 vaccinia related kinase 2 2.32299
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 2.30742
ZFP36 ZFP36 ring finger protein 2.3069
PEX5 peroxisomal biogenesis factor 5 2.2435
CREBL2 cAMP responsive element binding protein-like 2 2.22046
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.22036
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 2.16359
PLRG1 pleiotropic regulator 1 2.16323
BTG1 B-cell translocation gene 1, anti-proliferative 2.16145
RPS25 ribosomal protein S25 2.15274
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.13007
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.12195
RCAN1 regulator of calcineurin 1 2.12105
NACA nascent polypeptide-associated complex alpha subunit 2.07687
ZNF768 zinc finger protein 768 2.06925
BBX bobby sox homolog (Drosophila) 2.06834
CRBN cereblon 2.05188
ZNF398 zinc finger protein 398 2.04205
MARS methionyl-tRNA synthetase 2.03339
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.03269
RPLP0 ribosomal protein, large, P0 2.02463
ZZZ3 zinc finger, ZZ-type containing 3 2.0064
SPIDR scaffolding protein involved in DNA repair 2.00413
C18ORF25 chromosome 18 open reading frame 25 1.99167
GPX1 glutathione peroxidase 1 1.98861
RPL39 ribosomal protein L39 1.98826
ZNF574 zinc finger protein 574 1.96972
AMMECR1L AMMECR1-like 1.9543
SNHG19 small nucleolar RNA host gene 19 1.94946
CDYL chromodomain protein, Y-like 1.9472
PHYH phytanoyl-CoA 2-hydroxylase 1.94667
TMEM128 transmembrane protein 128 1.94068
RBM38 RNA binding motif protein 38 1.93366
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.90773
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1.90382
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 1.89593
TXNDC15 thioredoxin domain containing 15 1.85982
H2AFJ H2A histone family, member J 1.85512
DNASE2 deoxyribonuclease II, lysosomal 1.85457
MRPS14 mitochondrial ribosomal protein S14 1.8403
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 1.8396
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.83791
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 1.82441
ZNRF3 zinc and ring finger 3 1.81587
EPB41L4A-AS1 EPB41L4A antisense RNA 1 1.81147
OPTN optineurin 1.80647
THUMPD3-AS1 THUMPD3 antisense RNA 1 1.80026
UIMC1 ubiquitin interaction motif containing 1 1.77176
RPL30 ribosomal protein L30 1.76554
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 1.75457
ACOT13 acyl-CoA thioesterase 13 1.74648
KLF3 Kruppel-like factor 3 (basic) 1.74175
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.73682
RPS29 ribosomal protein S29 1.73492
PLD2 phospholipase D2 1.73046
PITPNA phosphatidylinositol transfer protein, alpha 1.72194
TNRC6B trinucleotide repeat containing 6B 1.72055
RPL29 ribosomal protein L29 1.71356
ACTN4 actinin, alpha 4 1.71066
SERP1 stress-associated endoplasmic reticulum protein 1 1.69464
SMC5 structural maintenance of chromosomes 5 1.69137
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.68898
RBM42 RNA binding motif protein 42 1.68745
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 1.68097
HINFP histone H4 transcription factor 1.67912
TMTC2 transmembrane and tetratricopeptide repeat containing 2 1.66673
RBMS2 RNA binding motif, single stranded interacting protein 2 1.66611
C15ORF52 chromosome 15 open reading frame 52 1.66271
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 1.65132
FJX1 four jointed box 1 (Drosophila) 1.63245
RAB24 RAB24, member RAS oncogene family 1.62875
ABHD14B abhydrolase domain containing 14B 1.62099
SYF2 SYF2 pre-mRNA-splicing factor 1.61687
OXLD1 oxidoreductase-like domain containing 1 1.61233
TRIM7 tripartite motif containing 7 1.61209
ICT1 immature colon carcinoma transcript 1 1.59905
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 1.59753
TOM1L1 target of myb1 (chicken)-like 1 1.5963
CSRP1 cysteine and glycine-rich protein 1 1.58912
STXBP1 syntaxin binding protein 1 1.57975
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.57836
AGGF1 angiogenic factor with G patch and FHA domains 1 1.57706
MVP major vault protein 1.57675
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 1.57131
HRCT1 histidine rich carboxyl terminus 1 1.57086
RNF169 ring finger protein 169 1.57026
UCKL1 uridine-cytidine kinase 1-like 1 1.56228
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.56154
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.55848
RPS5 ribosomal protein S5 1.55841
POGLUT1 protein O-glucosyltransferase 1 1.55278
WWTR1 WW domain containing transcription regulator 1 1.55036
NFE2L1 nuclear factor, erythroid 2-like 1 1.55001
CDKN2A cyclin-dependent kinase inhibitor 2A 1.54908
LINC00638 long intergenic non-protein coding RNA 638 1.53885
MATN1-AS1 MATN1 antisense RNA 1 1.53604
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.53261
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.53252
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 1.52867
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.52501
PYCR1 pyrroline-5-carboxylate reductase 1 1.51111
TPT1 tumor protein, translationally-controlled 1 1.50464
MPC1 mitochondrial pyruvate carrier 1 1.50034
LAMB1 laminin, beta 1 1.50024
MARCKS myristoylated alanine-rich protein kinase C substrate 1.49833
TTC30B tetratricopeptide repeat domain 30B 1.48517
DCP1B decapping mRNA 1B 1.48437
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.48399
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 1.48323
TIAM1 T-cell lymphoma invasion and metastasis 1 1.48292
DPP8 dipeptidyl-peptidase 8 1.4696
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 1.46627
KDM3B lysine (K)-specific demethylase 3B 1.45514
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 1.45012
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.4477
DEF8 differentially expressed in FDCP 8 homolog (mouse) 1.44148
GADD45B growth arrest and DNA-damage-inducible, beta 1.4334
C19ORF66 chromosome 19 open reading frame 66 1.43291
PABPC3 poly(A) binding protein, cytoplasmic 3 1.43268
EPRS glutamyl-prolyl-tRNA synthetase 1.42545
IFT43 intraflagellar transport 43 1.42524
DPH5 diphthamide biosynthesis 5 1.42467
TMEM47 transmembrane protein 47 1.42333
FAM129A family with sequence similarity 129, member A 1.41707
KRI1 KRI1 homolog (S. cerevisiae) 1.41134
ZBED3 zinc finger, BED-type containing 3 1.41012
EIF6 eukaryotic translation initiation factor 6 1.40887
RANBP9 RAN binding protein 9 1.40676
CCDC25 coiled-coil domain containing 25 1.40372
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.40253
LAMP2 lysosomal-associated membrane protein 2 1.40122
NXPE3 neurexophilin and PC-esterase domain family, member 3 1.39881
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.39735
PTTG1IP pituitary tumor-transforming 1 interacting protein 1.38899
LINC00667 long intergenic non-protein coding RNA 667 1.385
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 1.36371
N4BP2L2 NEDD4 binding protein 2-like 2 1.35984
TEAD3 TEA domain family member 3 1.35849
WARS tryptophanyl-tRNA synthetase 1.35765
NOD1 nucleotide-binding oligomerization domain containing 1 1.35696
RPL36 ribosomal protein L36 1.35419
RICTOR RPTOR independent companion of MTOR, complex 2 1.35378
PDE4C phosphodiesterase 4C, cAMP-specific 1.35249
HAX1 HCLS1 associated protein X-1 1.34908
WBP4 WW domain binding protein 4 1.34301
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 1.33347
SEPT8 septin 8 1.32379
MID1IP1 MID1 interacting protein 1 1.3197
LOC101929406 uncharacterized LOC101929406 1.31776
WAC WW domain containing adaptor with coiled-coil 1.30787
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.30557
C1ORF216 chromosome 1 open reading frame 216 1.30153
HOXC6 homeobox C6 1.30093
EXOC8 exocyst complex component 8 1.29933
C18ORF21 chromosome 18 open reading frame 21 1.29795
MAN2C1 mannosidase, alpha, class 2C, member 1 1.29124
LONP1 lon peptidase 1, mitochondrial 1.29065
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.28681
DIS3L DIS3 like exosome 3'-5' exoribonuclease 1.28123
KIAA1033 KIAA1033 1.27975
COTL1 coactosin-like F-actin binding protein 1 1.27525
RPL15 ribosomal protein L15 1.27355
LOC100287590 uncharacterized LOC100287590 1.27304
CEP120 centrosomal protein 120kDa 1.25604
NT5E 5'-nucleotidase, ecto (CD73) 1.25392
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 1.25315
LOC100506258 uncharacterized LOC100506258 1.25224
ZMAT2 zinc finger, matrin-type 2 1.24912
CNN3 calponin 3, acidic 1.24523
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.24464
PLK3 polo-like kinase 3 1.24237
TSEN15 TSEN15 tRNA splicing endonuclease subunit 1.23607
JDP2 Jun dimerization protein 2 1.23575
MZT2A mitotic spindle organizing protein 2A 1.23516
CDC25B cell division cycle 25B 1.23435
LINC01410 long intergenic non-protein coding RNA 1410 1.23109
IFT46 intraflagellar transport 46 1.22943
RPN2 ribophorin II 1.22873
NUPR1 nuclear protein, transcriptional regulator, 1 1.22719
TSPAN31 tetraspanin 31 1.22615
BAIAP2L1 BAI1-associated protein 2-like 1 1.22524
MPND MPN domain containing 1.21883
SLC22A15 solute carrier family 22, member 15 1.21875
PFN2 profilin 2 1.21766
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 1.21685
MAOA monoamine oxidase A 1.21558
C15ORF40 chromosome 15 open reading frame 40 1.21173
KHNYN KH and NYN domain containing 1.21148
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 1.20968
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.20676
SECISBP2L SECIS binding protein 2-like 1.20375
FBXL4 F-box and leucine-rich repeat protein 4 1.2
BBS12 Bardet-Biedl syndrome 12 1.197
RPL37 ribosomal protein L37 1.19252
ANXA2P2 annexin A2 pseudogene 2 1.19059
CSNK1G2 casein kinase 1, gamma 2 1.18958
FAM111A family with sequence similarity 111, member A 1.18292
PMM1 phosphomannomutase 1 1.17591
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 1.17055
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 1.17001
ANAPC16 anaphase promoting complex subunit 16 1.16758
NFYC-AS1 NFYC antisense RNA 1 1.16469
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1.16466
FAM76B family with sequence similarity 76, member B 1.1636
CLUAP1 clusterin associated protein 1 1.16358
ZFP30 ZFP30 zinc finger protein 1.15365
STX16 syntaxin 16 1.14677
LENG9 leukocyte receptor cluster (LRC) member 9 1.14525
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 1.13775
TCHH trichohyalin 1.13599
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 1.13435
RP9 retinitis pigmentosa 9 (autosomal dominant) 1.13432
MKRN1 makorin ring finger protein 1 1.13326
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.13224
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 1.13169
TBRG4 transforming growth factor beta regulator 4 1.13076
NCR3 natural cytotoxicity triggering receptor 3 1.12982
RPL36AL ribosomal protein L36a-like 1.12946
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.12942
NOA1 nitric oxide associated 1 1.12837
GOLGA2 golgin A2 1.12742
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 1.12721
VEGFA vascular endothelial growth factor A 1.11981
MLIP muscular LMNA-interacting protein 1.1183
TST thiosulfate sulfurtransferase (rhodanese) 1.11576
TUBA1A tubulin, alpha 1a 1.11173
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.11096
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 1.11061
RNF44 ring finger protein 44 1.10984
TRIB3 tribbles pseudokinase 3 1.10854
LRRC37B leucine rich repeat containing 37B 1.10743
H1FX H1 histone family, member X 1.10299
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.09743
TMEM14C transmembrane protein 14C 1.09448
SLFN5 schlafen family member 5 1.09431
LRP12 low density lipoprotein receptor-related protein 12 1.09016
AGK acylglycerol kinase 1.08419
LINC00853 long intergenic non-protein coding RNA 853 1.07961
SPPL2B signal peptide peptidase like 2B 1.07785
APH1B APH1B gamma secretase subunit 1.07518
RPL31 ribosomal protein L31 1.07285
RHOT1 ras homolog family member T1 1.07154
AKIRIN2 akirin 2 1.07002
NRBP2 nuclear receptor binding protein 2 1.0699
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.06976
ZNF197 zinc finger protein 197 1.06737
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.06537
ENDOG endonuclease G 1.06351
SCN1A sodium channel, voltage gated, type I alpha subunit 1.06267
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.06226
ARF3 ADP-ribosylation factor 3 1.05703
CEP70 centrosomal protein 70kDa 1.05671
ACTB actin, beta 1.0563
TNNT1 troponin T type 1 (skeletal, slow) 1.05309
CD99 CD99 molecule 1.04848
VWA8 von Willebrand factor A domain containing 8 1.0463
PCM1 pericentriolar material 1 1.04605
GAS8 growth arrest-specific 8 1.03937
CLIP3 CAP-GLY domain containing linker protein 3 1.03767
LHFP lipoma HMGIC fusion partner 1.03716
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.03259
RSL1D1 ribosomal L1 domain containing 1 1.03052
MAN1B1 mannosidase, alpha, class 1B, member 1 1.02997
CNOT1 CCR4-NOT transcription complex, subunit 1 1.02987

decreased expression

Symbol Name Standardized Value
FBXO45 F-box protein 45 -5.17738
TMX1 thioredoxin-related transmembrane protein 1 -4.20784
MAP2K1 mitogen-activated protein kinase kinase 1 -3.96811
SVIP small VCP/p97-interacting protein -3.71621
RAP2B RAP2B, member of RAS oncogene family -3.28279
ENO2 enolase 2 (gamma, neuronal) -3.25847
SGOL2 shugoshin-like 2 (S. pombe) -3.08838
VBP1 von Hippel-Lindau binding protein 1 -2.95457
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.90983
NABP1 nucleic acid binding protein 1 -2.90382
TMEM14A transmembrane protein 14A -2.90024
MTDH metadherin -2.89993
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.76646
GLMN glomulin, FKBP associated protein -2.68567
BCAP31 B-cell receptor-associated protein 31 -2.6619
GMCL1 germ cell-less, spermatogenesis associated 1 -2.57604
HILPDA hypoxia inducible lipid droplet-associated -2.55355
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.49185
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -2.48777
SETX senataxin -2.48716
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -2.47151
GBE1 glucan (1,4-alpha-), branching enzyme 1 -2.40495
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -2.39432
KPNB1 karyopherin (importin) beta 1 -2.37583
TCP1 t-complex 1 -2.37254
MRPL27 mitochondrial ribosomal protein L27 -2.34347
PRADC1 protease-associated domain containing 1 -2.32498
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.3237
TM9SF2 transmembrane 9 superfamily member 2 -2.32186
HCCS holocytochrome c synthase -2.31005
PUF60 poly-U binding splicing factor 60KDa -2.28055
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.27142
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.26144
CCNH cyclin H -2.25533
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.2546
RPP14 ribonuclease P/MRP 14kDa subunit -2.25388
SRM spermidine synthase -2.22554
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.2153
LAPTM4B lysosomal protein transmembrane 4 beta -2.19465
RPA2 replication protein A2, 32kDa -2.18591
CYB561D2 cytochrome b561 family, member D2 -2.18094
ADI1 acireductone dioxygenase 1 -2.16735
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -2.16584
BAZ1A bromodomain adjacent to zinc finger domain, 1A -2.15656
TRIM27 tripartite motif containing 27 -2.1128
PRELID1 PRELI domain containing 1 -2.10819
DERL2 derlin 2 -2.10586
ISOC1 isochorismatase domain containing 1 -2.10419
SYPL1 synaptophysin-like 1 -2.098
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.08268
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.07888
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.07247
PNPLA8 patatin-like phospholipase domain containing 8 -2.07127
TCF19 transcription factor 19 -2.05377
PARP2 poly (ADP-ribose) polymerase 2 -2.03913
ASNSD1 asparagine synthetase domain containing 1 -2.03851
MRPS24 mitochondrial ribosomal protein S24 -1.99855
MMP16 matrix metallopeptidase 16 (membrane-inserted) -1.98071
LXN latexin -1.97579
ZNF706 zinc finger protein 706 -1.95889
PGK1 phosphoglycerate kinase 1 -1.95144
TMEM14B transmembrane protein 14B -1.94484
VTA1 vesicle (multivesicular body) trafficking 1 -1.92133
POLR1C polymerase (RNA) I polypeptide C, 30kDa -1.92006
SMG5 SMG5 nonsense mediated mRNA decay factor -1.912
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -1.8705
HSBP1 heat shock factor binding protein 1 -1.86483
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -1.86424
ZBTB8OS zinc finger and BTB domain containing 8 opposite strand -1.84836
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -1.84187
DHFRL1 dihydrofolate reductase-like 1 -1.81147
MANF mesencephalic astrocyte-derived neurotrophic factor -1.81065
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -1.78128
EMC6 ER membrane protein complex subunit 6 -1.77274
MPZL1 myelin protein zero-like 1 -1.76895
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted -1.76281
WRB tryptophan rich basic protein -1.74697
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -1.73774
RABGGTA Rab geranylgeranyltransferase, alpha subunit -1.73608
RINT1 RAD50 interactor 1 -1.72978
BARD1 BRCA1 associated RING domain 1 -1.72881
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.72837
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -1.72149
CXORF38 chromosome X open reading frame 38 -1.7147
HAUS2 HAUS augmin-like complex, subunit 2 -1.71361
PANK3 pantothenate kinase 3 -1.70843
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.70426
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -1.70199
ARL5A ADP-ribosylation factor-like 5A -1.70093
LARS2 leucyl-tRNA synthetase 2, mitochondrial -1.68634
TRAPPC3 trafficking protein particle complex 3 -1.6833
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli) -1.67554
HAT1 histone acetyltransferase 1 -1.67437
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -1.67323
KRT10 keratin 10, type I -1.66993
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 -1.66695
TMCO1 transmembrane and coiled-coil domains 1 -1.65888
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -1.64803
CYCS cytochrome c, somatic -1.6474
RAD51C RAD51 paralog C -1.64278
SNRPE small nuclear ribonucleoprotein polypeptide E -1.64152
HOXA5 homeobox A5 -1.62749
PGM1 phosphoglucomutase 1 -1.62031
CCDC47 coiled-coil domain containing 47 -1.61603
MED8 mediator complex subunit 8 -1.61347
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -1.59921
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -1.59821
UVRAG UV radiation resistance associated -1.57594
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -1.57449
CCNYL1 cyclin Y-like 1 -1.57379
PUSL1 pseudouridylate synthase-like 1 -1.5663
PPP1R8 protein phosphatase 1, regulatory subunit 8 -1.56336
SLC18B1 solute carrier family 18, subfamily B, member 1 -1.55996
SAP130 Sin3A-associated protein, 130kDa -1.55434
SCML1 sex comb on midleg-like 1 (Drosophila) -1.53204
ZWINT ZW10 interacting kinetochore protein -1.51892
GLO1 glyoxalase I -1.51696
C19ORF24 chromosome 19 open reading frame 24 -1.51695
ARPC5L actin related protein 2/3 complex, subunit 5-like -1.51582
C11ORF30 chromosome 11 open reading frame 30 -1.50341
ALYREF Aly/REF export factor -1.50153
CBWD1 COBW domain containing 1 -1.49254
BIRC5 baculoviral IAP repeat containing 5 -1.49216
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -1.48775
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -1.48667
OXSM 3-oxoacyl-ACP synthase, mitochondrial -1.47209
YAE1D1 Yae1 domain containing 1 -1.46444
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.4639
FTSJ3 FtsJ homolog 3 (E. coli) -1.4597
CASP6 caspase 6, apoptosis-related cysteine peptidase -1.44897
CD320 CD320 molecule -1.42837
PHTF1 putative homeodomain transcription factor 1 -1.42447
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) -1.41996
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -1.4093
BCLAF1 BCL2-associated transcription factor 1 -1.40171
FDX1 ferredoxin 1 -1.40009
CRY1 cryptochrome circadian clock 1 -1.39486
PTOV1-AS1 PTOV1 antisense RNA 1 -1.39019
EXOSC4 exosome component 4 -1.38578
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -1.37452
C2ORF69 chromosome 2 open reading frame 69 -1.36696
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -1.35947
GNPDA2 glucosamine-6-phosphate deaminase 2 -1.33364
CIB1 calcium and integrin binding 1 (calmyrin) -1.33209
C8ORF33 chromosome 8 open reading frame 33 -1.32265
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -1.32212
ARL6 ADP-ribosylation factor-like 6 -1.31999
TMEM170A transmembrane protein 170A -1.31195
PFDN2 prefoldin subunit 2 -1.29945
COMMD9 COMM domain containing 9 -1.29812
ELOVL1 ELOVL fatty acid elongase 1 -1.29807
PPP6C protein phosphatase 6, catalytic subunit -1.29468
TRMT5 tRNA methyltransferase 5 -1.28892
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -1.28824
LYRM7 LYR motif containing 7 -1.27251
MSH2 mutS homolog 2 -1.27105
ATG5 autophagy related 5 -1.26574
C3ORF14 chromosome 3 open reading frame 14 -1.26069
AMD1 adenosylmethionine decarboxylase 1 -1.2601
SZRD1 SUZ RNA binding domain containing 1 -1.2527
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.23802
TEX2 testis expressed 2 -1.2379
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.2371
RNASEK ribonuclease, RNase K -1.23313
SYS1 Sys1 golgi trafficking protein -1.22608
MRPL49 mitochondrial ribosomal protein L49 -1.2159
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -1.21319
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -1.19669
GPN2 GPN-loop GTPase 2 -1.19531
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -1.18581
CALML3 calmodulin-like 3 -1.17752
SELT selenoprotein T -1.17487
FBXO33 F-box protein 33 -1.17192
HMGN5 high mobility group nucleosome binding domain 5 -1.1719
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -1.17156
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -1.16764
APOA1BP apolipoprotein A-I binding protein -1.15939
TMEM167A transmembrane protein 167A -1.15848
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) -1.15817
OIP5 Opa interacting protein 5 -1.15773
MED21 mediator complex subunit 21 -1.15767
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -1.15488
MRPS28 mitochondrial ribosomal protein S28 -1.15352
MTX2 metaxin 2 -1.14686
ZBTB9 zinc finger and BTB domain containing 9 -1.14568
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -1.14379
RMDN3 regulator of microtubule dynamics 3 -1.14233
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.1406
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -1.13453
ARHGAP5 Rho GTPase activating protein 5 -1.13294
ZFYVE19 zinc finger, FYVE domain containing 19 -1.12821
SCYL3 SCY1-like 3 (S. cerevisiae) -1.12511
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -1.12479
PPME1 protein phosphatase methylesterase 1 -1.11649
ALAS1 5'-aminolevulinate synthase 1 -1.11145
TRMT6 tRNA methyltransferase 6 -1.10334
TRAPPC8 trafficking protein particle complex 8 -1.10202
ZBTB43 zinc finger and BTB domain containing 43 -1.09757
NOL11 nucleolar protein 11 -1.09754
MEA1 male-enhanced antigen 1 -1.09265
SAR1B secretion associated, Ras related GTPase 1B -1.09152
PTDSS1 phosphatidylserine synthase 1 -1.0911
RWDD4 RWD domain containing 4 -1.0899
TSNAX translin-associated factor X -1.08676
CDC26 cell division cycle 26 -1.08152
NDC1 NDC1 transmembrane nucleoporin -1.0812
METTL8 methyltransferase like 8 -1.07867
MRPS35 mitochondrial ribosomal protein S35 -1.07304
RNF114 ring finger protein 114 -1.0722
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -1.05969
YIPF5 Yip1 domain family, member 5 -1.05843
CERS6 ceramide synthase 6 -1.05622
PCIF1 PDX1 C-terminal inhibiting factor 1 -1.05617
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -1.05473
RAB23 RAB23, member RAS oncogene family -1.05469
HMGN1 high mobility group nucleosome binding domain 1 -1.05332
MFAP3 microfibrillar-associated protein 3 -1.05287
LOC283683 uncharacterized LOC283683 -1.05232
FANCM Fanconi anemia, complementation group M -1.05223
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -1.05035
C20ORF24 chromosome 20 open reading frame 24 -1.04898
TMEM45A transmembrane protein 45A -1.04457
RILPL2 Rab interacting lysosomal protein-like 2 -1.04264
COPS8 COP9 signalosome subunit 8 -1.04131
RAB8A RAB8A, member RAS oncogene family -1.03913
PBDC1 polysaccharide biosynthesis domain containing 1 -1.03829
CEP85 centrosomal protein 85kDa -1.03709
MPP1 membrane protein, palmitoylated 1, 55kDa -1.03297
PTRH2 peptidyl-tRNA hydrolase 2 -1.02821
TIPRL TOR signaling pathway regulator -1.0215
SREK1IP1 SREK1-interacting protein 1 -1.01976
FARSA phenylalanyl-tRNA synthetase, alpha subunit -1.01907
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -1.01749
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -1.01401
TMEM130 transmembrane protein 130 -1.00911
MSI2 musashi RNA-binding protein 2 -1.00889
HSPA4L heat shock 70kDa protein 4-like -1.00759
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.00328
RRBP1 ribosome binding protein 1 -1.00216
MYDGF myeloid-derived growth factor -1.00115
CTSA cathepsin A -0.998806
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -0.997956
MRPL33 mitochondrial ribosomal protein L33 -0.981595
YTHDC2 YTH domain containing 2 -0.979387
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -0.973378
BCL7C B-cell CLL/lymphoma 7C -0.973207
CISD1 CDGSH iron sulfur domain 1 -0.973185
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -0.972765
SEPHS1 selenophosphate synthetase 1 -0.972036
CCDC86 coiled-coil domain containing 86 -0.968829
MUT methylmalonyl CoA mutase -0.967669
MMGT1 membrane magnesium transporter 1 -0.966341
MED10 mediator complex subunit 10 -0.964979
LMAN1 lectin, mannose-binding, 1 -0.962585
C10ORF12 chromosome 10 open reading frame 12 -0.962161
SKA2 spindle and kinetochore associated complex subunit 2 -0.956095
LOC151484 uncharacterized LOC151484 -0.953543
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -0.952547
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.951473
TRAF3 TNF receptor-associated factor 3 -0.951357
TXNDC17 thioredoxin domain containing 17 -0.949832
ZNF254 zinc finger protein 254 -0.946577
PNMAL1 paraneoplastic Ma antigen family-like 1 -0.946097
CIR1 corepressor interacting with RBPJ, 1 -0.944341
PNP purine nucleoside phosphorylase -0.942058
TTC1 tetratricopeptide repeat domain 1 -0.940027
LSM10 LSM10, U7 small nuclear RNA associated -0.934409
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -0.93346
C4ORF29 chromosome 4 open reading frame 29 -0.932962
PGM2 phosphoglucomutase 2 -0.928713
BCAS2 breast carcinoma amplified sequence 2 -0.926431
MYEF2 myelin expression factor 2 -0.923257
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -0.921993
TEX264 testis expressed 264 -0.921145
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -0.920852
PPAN peter pan homolog (Drosophila) -0.920691
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.917975
CEP76 centrosomal protein 76kDa -0.917746
BIRC6 baculoviral IAP repeat containing 6 -0.915379
PPA1 pyrophosphatase (inorganic) 1 -0.915206
ADIPOR1 adiponectin receptor 1 -0.914903
ANAPC10 anaphase promoting complex subunit 10 -0.912969
MKKS McKusick-Kaufman syndrome -0.912929
MFSD5 major facilitator superfamily domain containing 5 -0.912019
E2F7 E2F transcription factor 7 -0.909496
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.904867
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -0.904765
ZMPSTE24 zinc metallopeptidase STE24 -0.904112
PEX3 peroxisomal biogenesis factor 3 -0.904028
LOC643711 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) pseudogene -0.90367
MAD2L1BP MAD2L1 binding protein -0.902246
CNOT6 CCR4-NOT transcription complex, subunit 6 -0.901169
TDP1 tyrosyl-DNA phosphodiesterase 1 -0.899886
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -0.896331
MPHOSPH9 M-phase phosphoprotein 9 -0.896238
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -0.885805
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.88353
PDZD8 PDZ domain containing 8 -0.881516
NUDCD1 NudC domain containing 1 -0.878911
LSM11 LSM11, U7 small nuclear RNA associated -0.878221