WHRN Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description whirlin (NCBI Entrez Gene Database, 25861)
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Genes

357 genes differentially expressed following the WHRN gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GJA4 gap junction protein, alpha 4, 37kDa 2.99069
UNC13C unc-13 homolog C (C. elegans) 2.99069
PEAR1 platelet endothelial aggregation receptor 1 2.99069
DRICH1 aspartate-rich 1 2.99069
SH2D6 SH2 domain containing 6 2.99069
SPICE1 spindle and centriole associated protein 1 2.99069
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 2.99069
LRRC56 leucine rich repeat containing 56 2.99069
FOLR3 folate receptor 3 (gamma) 2.99069
GFI1 growth factor independent 1 transcription repressor 2.99069
CXCL2 chemokine (C-X-C motif) ligand 2 2.99069
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.99069
BTLA B and T lymphocyte associated 2.99069
PCDHB7 protocadherin beta 7 2.99069
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.99069
UPK3B uroplakin 3B 2.99069
AGTR1 angiotensin II receptor, type 1 2.99069
CEMP1 cementum protein 1 2.99069
WDR87 WD repeat domain 87 2.99069
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 2.99069
LIPH lipase, member H 2.99069
NXPH4 neurexophilin 4 2.99069
BTK Bruton agammaglobulinemia tyrosine kinase 2.99069
MUC6 mucin 6, oligomeric mucus/gel-forming 2.99069
NOTUM notum pectinacetylesterase homolog (Drosophila) 2.99069
OR13C3 olfactory receptor, family 13, subfamily C, member 3 2.99069
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.99069
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.99069
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 2.99069
EPHB3 EPH receptor B3 2.99069
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.99069
RNASE9 ribonuclease, RNase A family, 9 (non-active) 2.99069
VENTX VENT homeobox 2.99069
PRSS22 protease, serine, 22 2.99069
NRSN1 neurensin 1 2.99069
DSPP dentin sialophosphoprotein 2.99069
ACY3 aminoacylase 3 2.99069
MYO1G myosin IG 2.99069
FAM216B family with sequence similarity 216, member B 2.99069
C1ORF141 chromosome 1 open reading frame 141 2.99069
HCST hematopoietic cell signal transducer 2.99069
NLRP10 NLR family, pyrin domain containing 10 2.99069
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.99069
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.99069
DLX4 distal-less homeobox 4 2.99069
F2 coagulation factor II (thrombin) 2.99069
MAGED4 melanoma antigen family D4 2.99069
SHE Src homology 2 domain containing E 2.99069
HBM hemoglobin, mu 2.99069
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 2.99069
SPMIP10 sperm microtubule inner protein 10 2.99069
GPX6 glutathione peroxidase 6 2.99069
LDB3 LIM domain binding 3 2.99069
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 2.99069
PCP4L1 Purkinje cell protein 4 like 1 2.99069
IMPG2 interphotoreceptor matrix proteoglycan 2 2.99069
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.99069
CSAG1 chondrosarcoma associated gene 1 2.99069
DLK2 delta-like 2 homolog (Drosophila) 2.99069
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 2.99069
ARHGAP15 Rho GTPase activating protein 15 2.99069
SAPCD1 suppressor APC domain containing 1 2.99069
GIPC3 GIPC PDZ domain containing family, member 3 2.99069
DEFB108B defensin, beta 108B 2.99069
LOC124906010 uncharacterized LOC124906010 2.99069
LOC122526780 uncharacterized LOC122526780 2.99069
H4C14 H4 clustered histone 14 2.99069
SERTM2 serine rich and transmembrane domain containing 2 2.99069
H2BC3 H2B clustered histone 3 2.99069
ERFE erythroferrone 2.99069
CIROP ciliated left-right organizer metallopeptidase 2.99069
GASK1B golgi associated kinase 1B 2.99069
H4C1 H4 clustered histone 1 2.99069
TTLL13 tubulin tyrosine ligase like 13 2.99069
CCR9 chemokine (C-C motif) receptor 9 2.99069
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.99069
TMIE transmembrane inner ear 2.99069
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 2.99069
ARL5C ADP-ribosylation factor-like 5C 2.99069
RHOXF2 Rhox homeobox family, member 2 2.99069
RLBP1 retinaldehyde binding protein 1 2.99069
ATP13A4 ATPase type 13A4 2.99069
BPIFA2 BPI fold containing family A, member 2 2.99069
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.99069
SLC22A10 solute carrier family 22, member 10 2.99069
RNF151 ring finger protein 151 2.99069
CFAP99 cilia and flagella associated protein 99 2.99069
TUBA3E tubulin, alpha 3e 2.99069
CHRD chordin 2.99069
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.99069
ZIC4 Zic family member 4 2.99069
CXCL16 chemokine (C-X-C motif) ligand 16 2.99069
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 2.99069
UROC1 urocanate hydratase 1 2.99069
C10ORF67 chromosome 10 open reading frame 67 2.99069
SCN10A sodium channel, voltage gated, type X alpha subunit 2.99069
IL31RA interleukin 31 receptor A 2.99069
BBS5 Bardet-Biedl syndrome 5 2.99069
WNT11 wingless-type MMTV integration site family, member 11 2.99069
NDRG1 N-myc downstream regulated 1 2.99069
CDH10 cadherin 10, type 2 (T2-cadherin) 2.99069
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.99069
MORN5 MORN repeat containing 5 2.99069
ARR3 arrestin 3, retinal (X-arrestin) 2.99069
CRHBP corticotropin releasing hormone binding protein 2.99069
TMEM132D transmembrane protein 132D 2.99069
MYF5 myogenic factor 5 2.99069
FNDC9 fibronectin type III domain containing 9 2.99069
DLX3 distal-less homeobox 3 2.99069
FNDC1 fibronectin type III domain containing 1 2.99069
CCDC152 coiled-coil domain containing 152 2.99069
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.99069
OR52N5 olfactory receptor, family 52, subfamily N, member 5 2.99069
MYLK2 myosin light chain kinase 2 2.99069
NKX6-3 NK6 homeobox 3 2.99069
GFY golgi-associated, olfactory signaling regulator 2.99069
PCDHGB5 protocadherin gamma subfamily B, 5 2.99069
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.99069
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.99069
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.99069
MR1 major histocompatibility complex, class I-related 2.99069
MAMLD1 mastermind-like domain containing 1 2.99069
TBXA2R thromboxane A2 receptor 2.99069
KRT222 keratin 222, type II 2.99069
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.99069
SPATA31E1 SPATA31 subfamily E, member 1 2.99069
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.99069
ALOXE3 arachidonate lipoxygenase 3 2.99069
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.99069
SLC22A24 solute carrier family 22, member 24 2.99069
MAMDC4 MAM domain containing 4 2.99069
ADGRA1 adhesion G protein-coupled receptor A1 2.99069
KLK6 kallikrein-related peptidase 6 2.99069
CDC20B cell division cycle 20B 2.99069
ASTL astacin-like metallo-endopeptidase (M12 family) 2.99069
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.99069
CFAP61 cilia and flagella associated protein 61 2.99069
HAMP hepcidin antimicrobial peptide 2.99069
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2.99069
SKAP1 src kinase associated phosphoprotein 1 2.99069
EYA4 EYA transcriptional coactivator and phosphatase 4 2.99069
TGM7 transglutaminase 7 2.99069
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 2.99069
STRC stereocilin 2.99069
TMEM45B transmembrane protein 45B 2.99069
ZNF831 zinc finger protein 831 2.99069
PRAP1 proline-rich acidic protein 1 2.99069
CD8B CD8b molecule 2.99069
PATE2 prostate and testis expressed 2 2.99069
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.99069
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.99069
NFE2 nuclear factor, erythroid 2 2.99069
ICAM5 intercellular adhesion molecule 5, telencephalin 2.99069
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.99069
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2.99069
NANOS3 nanos homolog 3 (Drosophila) 2.99069
MMP10 matrix metallopeptidase 10 2.99069
ANGPTL7 angiopoietin-like 7 2.99069
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.99069
ZPBP zona pellucida binding protein 2.99069
DEFB134 defensin, beta 134 2.99069
RUFY4 RUN and FYVE domain containing 4 2.99069
ESPNL espin-like 2.99069
IFIH1 interferon induced with helicase C domain 1 2.99069
CSPG4 chondroitin sulfate proteoglycan 4 2.99069
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.99069
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.99069
PLA2G4B phospholipase A2, group IVB (cytosolic) 2.99069
PMP2 peripheral myelin protein 2 2.99069
STMND1 stathmin domain containing 1 2.99069
MEIS1 Meis homeobox 1 2.99069
ADRA2C adrenoceptor alpha 2C 2.99069
POTEJ POTE ankyrin domain family, member J 2.99069
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.99069
ADGRF5 adhesion G protein-coupled receptor F5 2.99069
CARD9 caspase recruitment domain family, member 9 2.99069
LAMB3 laminin, beta 3 2.99069
C5AR2 complement component 5a receptor 2 2.99069
MB myoglobin 2.90636
MYZAP myocardial zonula adherens protein 2.89695
HBQ1 hemoglobin, theta 1 2.89482
GPR146 G protein-coupled receptor 146 2.89482
ZNF841 zinc finger protein 841 2.89482
KLK13 kallikrein-related peptidase 13 2.89482
CLTB clathrin, light chain B 2.88093
NHP2 NHP2 ribonucleoprotein 2.84035
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.76005
MT1X metallothionein 1X 2.76005
MPV17L2 MPV17 mitochondrial membrane protein-like 2 2.7525
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 2.73399
HOMEZ homeobox and leucine zipper encoding 2.68341
XPC xeroderma pigmentosum, complementation group C 2.656
SENP6 SUMO1/sentrin specific peptidase 6 2.65307
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2.62109
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.62109
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 2.5895
HEXD hexosaminidase D 2.56728
EBF3 early B-cell factor 3 2.55814
TENT5C terminal nucleotidyltransferase 5C 2.55814
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 2.55396
ITGA11 integrin, alpha 11 2.55396
ADAM11 ADAM metallopeptidase domain 11 2.55396
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.55396
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 2.55169
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.53669
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 2.50724
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 2.48901
CCND2 cyclin D2 2.4806
CRACDL CRACD like 2.43441
GBX1 gastrulation brain homeobox 1 2.43441
TMEM47 transmembrane protein 47 2.40252
TGIF1 TGFB-induced factor homeobox 1 2.3779
ACAT2 acetyl-CoA acetyltransferase 2 2.36304
NUP54 nucleoporin 54kDa 2.34428
SLC25A44 solute carrier family 25, member 44 2.34392
NRXN2 neurexin 2 2.28905
MAN2C1 mannosidase, alpha, class 2C, member 1 2.28905
ERG28 ergosterol biosynthesis 28 homolog 2.286
ZNF623 zinc finger protein 623 2.27812
TAC3 tachykinin 3 2.26125
C6ORF136 chromosome 6 open reading frame 136 2.24454
PON2 paraoxonase 2 2.24454
HLA-DMB major histocompatibility complex, class II, DM beta 2.17751
TIPIN TIMELESS interacting protein 2.17751
ALOX12 arachidonate 12-lipoxygenase 2.17751
FBXW9 F-box and WD repeat domain containing 9 2.16813
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 2.14789
ENTR1 endosome associated trafficking regulator 1 2.13009
CCM2 cerebral cavernous malformation 2 2.13009
MAPK10 mitogen-activated protein kinase 10 2.125
SOX5 SRY (sex determining region Y)-box 5 2.11796
SPATA2L spermatogenesis associated 2-like 2.08818
ESYT1 extended synaptotagmin-like protein 1 2.08396
NHLRC2 NHL repeat containing 2 2.06685
AKAP6 A kinase (PRKA) anchor protein 6 2.06202
STK31 serine/threonine kinase 31 2.06202
SIVA1 SIVA1, apoptosis-inducing factor 2.06202
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.06202
FRG1 FSHD region gene 1 2.06202
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.06202
IRF7 interferon regulatory factor 7 2.06202
SOX15 SRY (sex determining region Y)-box 15 2.06202
RUNDC3A RUN domain containing 3A 2.06202
CAV2 caveolin 2 2.06202
ATG3 autophagy related 3 2.04182
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 2.04182
ANKDD1A ankyrin repeat and death domain containing 1A 2.04178
RAD23B RAD23 homolog B (S. cerevisiae) 2.02147
RPS15 ribosomal protein S15 2.01583
STXBP2 syntaxin binding protein 2 2.00869

decreased expression

Symbol Name Standardized Value
NBN nibrin -2.99069
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.99069
AMIGO1 adhesion molecule with Ig-like domain 1 -2.99069
MYO15B myosin XVB -2.99069
KRIT1 KRIT1, ankyrin repeat containing -2.99069
MSS51 MSS51 mitochondrial translational activator -2.99069
PRX periaxin -2.99069
DRC3 dynein regulatory complex subunit 3 -2.99069
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -2.98904
CASKIN2 CASK interacting protein 2 -2.91872
FRZB frizzled-related protein -2.89482
STAG3 stromal antigen 3 -2.89482
MRPS27 mitochondrial ribosomal protein S27 -2.88206
ANKRD37 ankyrin repeat domain 37 -2.79124
C3ORF22 chromosome 3 open reading frame 22 -2.79124
ZNF575 zinc finger protein 575 -2.79124
LGALS9 lectin, galactoside-binding, soluble, 9 -2.79124
ADRA1A adrenoceptor alpha 1A -2.79124
TMEM213 transmembrane protein 213 -2.79124
CBLN1 cerebellin 1 precursor -2.79124
KLHL35 kelch-like family member 35 -2.79124
GGN gametogenetin -2.79124
SCIN scinderin -2.79124
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.79124
DNAH2 dynein, axonemal, heavy chain 2 -2.79124
ATG9B autophagy related 9B -2.79124
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -2.79124
CXCR5 chemokine (C-X-C motif) receptor 5 -2.79124
ADGRD1 adhesion G protein-coupled receptor D1 -2.79124
SLC45A1 solute carrier family 45, member 1 -2.79124
LMNTD2 lamin tail domain containing 2 -2.79124
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C -2.79124
PCDHGA5 protocadherin gamma subfamily A, 5 -2.79124
MUSTN1 musculoskeletal, embryonic nuclear protein 1 -2.79124
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -2.79124
CCNP cyclin P -2.79124
FYB2 FYN binding protein 2 -2.79124
GLT8D2 glycosyltransferase 8 domain containing 2 -2.79124
STARD6 StAR-related lipid transfer (START) domain containing 6 -2.79124
PLA2G5 phospholipase A2, group V -2.79124
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 -2.79124
AMPD3 adenosine monophosphate deaminase 3 -2.78325
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -2.78325
STAT4 signal transducer and activator of transcription 4 -2.74382
MYH11 myosin, heavy chain 11, smooth muscle -2.74382
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.74247
ACP1 acid phosphatase 1, soluble -2.64331
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.62589
BAALC brain and acute leukemia, cytoplasmic -2.62109
BNIPL BCL2/adenovirus E1B 19kD interacting protein like -2.62109
TMEM255B transmembrane protein 255B -2.62109
SMC1B structural maintenance of chromosomes 1B -2.62109
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type -2.62109
PTGR2 prostaglandin reductase 2 -2.61954
MRPL27 mitochondrial ribosomal protein L27 -2.59118
WHRN whirlin -2.56044
ATRX alpha thalassemia/mental retardation syndrome X-linked -2.50724
SLC35E4 solute carrier family 35, member E4 -2.496
C16ORF96 chromosome 16 open reading frame 96 -2.49553
CARMIL2 capping protein regulator and myosin 1 linker 2 -2.48783
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.43441
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -2.43331
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -2.39061
SCYL1 SCY1-like 1 (S. cerevisiae) -2.39061
TMEM178A transmembrane protein 178A -2.38467
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -2.35748
SDCCAG8 serologically defined colon cancer antigen 8 -2.35169
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.31902
MRPL4 mitochondrial ribosomal protein L4 -2.31052
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -2.31052
DLAT dihydrolipoamide S-acetyltransferase -2.28905
RAB7A RAB7A, member RAS oncogene family -2.286
EFNA3 ephrin-A3 -2.27482
GOLGA1 golgin A1 -2.26547
APIP APAF1 interacting protein -2.2084
SKIC3 SKI3 subunit of superkiller complex -2.17751
XXYLT1 xyloside xylosyltransferase 1 -2.16822
BMPER BMP binding endothelial regulator -2.16024
MPPE1 metallophosphoesterase 1 -2.15758
LIX1L Lix1 homolog (chicken) like -2.14789
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -2.14789
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 -2.14266
ARHGAP6 Rho GTPase activating protein 6 -2.13722
ZNF660-ZNF197 ZNF660-ZNF197 readthrough -2.13009
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.12596
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.12549
MXRA7 matrix-remodelling associated 7 -2.11607
ZNF765 zinc finger protein 765 -2.10039
SCART1 scavenger receptor protein family member -2.09835
CBY3 chibby homolog 3 (Drosophila) -2.09835
SIRT4 sirtuin 4 -2.09835
PODNL1 podocan-like 1 -2.09835
ASNS asparagine synthetase (glutamine-hydrolyzing) -2.09835
RASL11B RAS-like, family 11, member B -2.09835
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 -2.08195
AARS1 alanyl-tRNA synthetase 1 -2.07872
SLC44A3 solute carrier family 44, member 3 -2.07289
RND3 Rho family GTPase 3 -2.06471
KLF10 Kruppel-like factor 10 -2.06202
PFDN1 prefoldin subunit 1 -2.06202
ARL10 ADP-ribosylation factor-like 10 -2.06202
TMEM69 transmembrane protein 69 -2.04958
COQ8B coenzyme Q8B -2.04418
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.04178
RUFY1 RUN and FYVE domain containing 1 -2.03862
TRHDE thyrotropin-releasing hormone degrading enzyme -2.03609
EPN1 epsin 1 -2.00784