WNT1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description wingless-type MMTV integration site family, member 1|The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7471)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_WNT1
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Genes

107 co-expressed genes for WNT1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAM7 ADAM metallopeptidase domain 7
AKR1D1 aldo-keto reductase family 1, member D1
ANGPTL7 angiopoietin-like 7
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ART3 ADP-ribosyltransferase 3
ASTN1 astrotactin 1
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATRNL1 attractin-like 1
AVP arginine vasopressin
AVPR1A arginine vasopressin receptor 1A
BAAT bile acid CoA:amino acid N-acyltransferase
BHMT betaine--homocysteine S-methyltransferase
BMPER BMP binding endothelial regulator
BNC1 basonuclin 1
BRDT bromodomain, testis-specific
C1ORF21 chromosome 1 open reading frame 21
CA5A carbonic anhydrase VA, mitochondrial
CD3G CD3g molecule, gamma (CD3-TCR complex)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CRYBB3 crystallin, beta B3
CST5 cystatin D
CTRB1 chymotrypsinogen B1
CUL3 cullin 3
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDN dendrin
DMP1 dentin matrix acidic phosphoprotein 1
DOC2A double C2-like domains, alpha
DSC1 desmocollin 1
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EPHA7 EPH receptor A7
FOXH1 forkhead box H1
FOXN2 forkhead box N2
FSTL4 follistatin-like 4
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GIF gastric intrinsic factor (vitamin B synthesis)
GK2 glycerol kinase 2
GPR176 G protein-coupled receptor 176
GRM8 glutamate receptor, metabotropic 8
HCG4 HLA complex group 4 (non-protein coding)
HIPK2 homeodomain interacting protein kinase 2
HOXD9 homeobox D9
IFNA4 interferon, alpha 4
IL18RAP interleukin 18 receptor accessory protein
IRGC immunity-related GTPase family, cinema
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KIAA0391 KIAA0391
KIF1A kinesin family member 1A
KRT37 keratin 37, type I
LCAT lecithin-cholesterol acyltransferase
LCT lactase
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MATN4 matrilin 4
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MPHOSPH8 M-phase phosphoprotein 8
MTRF1L mitochondrial translational release factor 1-like
MYBPH myosin binding protein H
MYCNOS MYCN opposite strand
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NACAD NAC alpha domain containing
NEU3 sialidase 3 (membrane sialidase)
NLE1 notchless homolog 1 (Drosophila)
NMBR neuromedin B receptor
NPY5R neuropeptide Y receptor Y5
NTN3 netrin 3
ODF2 outer dense fiber of sperm tails 2
OPHN1 oligophrenin 1
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE9A phosphodiesterase 9A
PHKG2 phosphorylase kinase, gamma 2 (testis)
PRM2 protamine 2
PROL1 proline rich, lacrimal 1
PTGDR2 prostaglandin D2 receptor 2
RAB3A RAB3A, member RAS oncogene family
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBM17 RNA binding motif protein 17
RFPL1S RFPL1 antisense RNA 1
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPGRIP1L RPGRIP1-like
SAA4 serum amyloid A4, constitutive
SCN5A sodium channel, voltage gated, type V alpha subunit
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SOX3 SRY (sex determining region Y)-box 3
SPAG8 sperm associated antigen 8
SYT11 synaptotagmin XI
TCF15 transcription factor 15 (basic helix-loop-helix)
TEKT2 tektin 2 (testicular)
TMEM257 transmembrane protein 257
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNT2 troponin T type 2 (cardiac)
TRPC3 transient receptor potential cation channel, subfamily C, member 3
VIPR2 vasoactive intestinal peptide receptor 2
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WNT1 wingless-type MMTV integration site family, member 1
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZFY zinc finger protein, Y-linked
ZNF154 zinc finger protein 154
ZNF208 zinc finger protein 208
ZNF239 zinc finger protein 239
ZNF264 zinc finger protein 264