| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/WNT_UP.V1_UP |
| Similar Terms | |
| Downloads & Tools |
348 genes differentially expressed following the WNT_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ADGRG3 | adhesion G protein-coupled receptor G3 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit |
| ATP4B | ATPase, H+/K+ exchanging, beta polypeptide |
| AURKB | aurora kinase B |
| BCL7C | B-cell CLL/lymphoma 7C |
| BTG4 | B-cell translocation gene 4 |
| C8G | complement component 8, gamma polypeptide |
| CCDC86 | coiled-coil domain containing 86 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCR3 | chemokine (C-C motif) receptor 3 |
| CCR8 | chemokine (C-C motif) receptor 8 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD96 | CD96 molecule |
| CDH5 | cadherin 5, type 2 (vascular endothelium) |
| CFC1 | cripto, FRL-1, cryptic family 1 |
| CHRNA7 | cholinergic receptor, nicotinic, alpha 7 (neuronal) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CKAP4 | cytoskeleton-associated protein 4 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLDN6 | claudin 6 |
| CLDN8 | claudin 8 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLEC4E | C-type lectin domain family 4, member E |
| CNGA2 | cyclic nucleotide gated channel alpha 2 |
| COL4A4 | collagen, type IV, alpha 4 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRMP1 | collapsin response mediator protein 1 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 |
| CYP4A22 | cytochrome P450, family 4, subfamily A, polypeptide 22 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DCC | DCC netrin 1 receptor |
| DHCR24 | 24-dehydrocholesterol reductase |
| DNAJB13 | DnaJ (Hsp40) homolog, subfamily B, member 13 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DTNB | dystrobrevin, beta |
| EDA | ectodysplasin A |
| ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FGF18 | fibroblast growth factor 18 |
| FICD | FIC domain containing |
| FNTB | farnesyltransferase, CAAX box, beta |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXK1 | forkhead box K1 |
| FPR2 | formyl peptide receptor 2 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GDF15 | growth differentiation factor 15 |
| GHRH | growth hormone releasing hormone |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GLI1 | GLI family zinc finger 1 |
| GNMT | glycine N-methyltransferase |
| GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
| HES5 | hes family bHLH transcription factor 5 |
| HOXD10 | homeobox D10 |
| HOXD3 | homeobox D3 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HTRA3 | HtrA serine peptidase 3 |
| HYOU1 | hypoxia up-regulated 1 |
| IGF2 | insulin-like growth factor 2 |
| IL12B | interleukin 12B |
| IL6 | interleukin 6 |
| INHBB | inhibin, beta B |
| INSM1 | insulinoma-associated 1 |
| INSRR | insulin receptor-related receptor |
| IRX3 | iroquois homeobox 3 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat |
| KCNC3 | potassium channel, voltage gated Shaw related subfamily C, member 3 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ9 | potassium channel, inwardly rectifying subfamily J, member 9 |
| KCNK4 | potassium channel, two pore domain subfamily K, member 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
| KIFC1 | kinesin family member C1 |
| KLRC1 | killer cell lectin-like receptor subfamily C, member 1 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| KRT27 | keratin 27, type I |
| KRT85 | keratin 85, type II |
| KRT86 | keratin 86, type II |
| KRTAP8-1 | keratin associated protein 8-1 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) |
| LCAT | lecithin-cholesterol acyltransferase |
| LCN2 | lipocalin 2 |
| LRG1 | leucine-rich alpha-2-glycoprotein 1 |
| LTA | lymphotoxin alpha |
| LTB4R | leukotriene B4 receptor |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFAP2 | microfibrillar-associated protein 2 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MST1R | macrophage stimulating 1 receptor |
| MTF1 | metal-regulatory transcription factor 1 |
| MYO5B | myosin VB |
| MYOM1 | myomesin 1 |
| MYRF | myelin regulatory factor |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NEUROD2 | neuronal differentiation 2 |
| NF1 | neurofibromin 1 |
| NLRX1 | NLR family member X1 |
| NPY4R | neuropeptide Y receptor Y4 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OXT | oxytocin/neurophysin I prepropeptide |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PDC | phosducin |
| PDYN | prodynorphin |
| PKIB | protein kinase (cAMP-dependent, catalytic) inhibitor beta |
| PKLR | pyruvate kinase, liver and RBC |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLAC9 | placenta-specific 9 |
| PMF1 | polyamine-modulated factor 1 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit |
| POMC | proopiomelanocortin |
| POSTN | periostin, osteoblast specific factor |
| POU1F1 | POU class 1 homeobox 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT1 | palmitoyl-protein thioesterase 1 |
| PRL | prolactin |
| PRSS29P | protease, serine, 29, pseudogene |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| RAD9A | RAD9 homolog A (S. pombe) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBPMS | RNA binding protein with multiple splicing |
| REG1B | regenerating islet-derived 1 beta |
| RETNLB | resistin like beta |
| RNF112 | ring finger protein 112 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RSPO1 | R-spondin 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SDC4 | syndecan 4 |
| SEMA5B | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SETD6 | SET domain containing 6 |
| SFN | stratifin |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLN | sarcolipin |
| SNN | stannin |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STK36 | serine/threonine kinase 36 |
| STRN4 | striatin, calmodulin binding protein 4 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYT3 | synaptotagmin III |
| SYT9 | synaptotagmin IX |
| TCF3 | transcription factor 3 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TEF | thyrotrophic embryonic factor |
| TEN1 | TEN1 CST complex subunit |
| TFF3 | trefoil factor 3 (intestinal) |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| THRB | thyroid hormone receptor, beta |
| THYN1 | thymocyte nuclear protein 1 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TSPO2 | translocator protein 2 |
| UBXN11 | UBX domain protein 11 |
| UGT8 | UDP glycosyltransferase 8 |
| UTF1 | undifferentiated embryonic cell transcription factor 1 |
| UTS2R | urotensin 2 receptor |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VAX2 | ventral anterior homeobox 2 |
| XCR1 | chemokine (C motif) receptor 1 |
| ZFP92 | ZFP92 zinc finger protein |
| ZNF358 | zinc finger protein 358 |
| Symbol | Name |
|---|---|
| AARD | alanine and arginine rich domain containing protein |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) |
| ACVR1B | activin A receptor, type IB |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADAR | adenosine deaminase, RNA-specific |
| ADCY4 | adenylate cyclase 4 |
| ADRB1 | adrenoceptor beta 1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AIRE | autoimmune regulator |
| AKR1E2 | aldo-keto reductase family 1, member E2 |
| APC2 | adenomatosis polyposis coli 2 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C16ORF89 | chromosome 16 open reading frame 89 |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CCDC130 | coiled-coil domain containing 130 |
| CD44 | CD44 molecule (Indian blood group) |
| CD48 | CD48 molecule |
| CD5 | CD5 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD93 | CD93 molecule |
| CDO1 | cysteine dioxygenase type 1 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CECR5 | cat eye syndrome chromosome region, candidate 5 |
| CELF1 | CUGBP, Elav-like family member 1 |
| CFHR1 | complement factor H-related 1 |
| CLEC4D | C-type lectin domain family 4, member D |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| CMBL | carboxymethylenebutenolidase homolog (Pseudomonas) |
| CMPK2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial |
| CNTN1 | contactin 1 |
| COL9A1 | collagen, type IX, alpha 1 |
| CORT | cortistatin |
| CPN1 | carboxypeptidase N, polypeptide 1 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYTH1 | cytohesin 1 |
| DDX25 | DEAD (Asp-Glu-Ala-Asp) box helicase 25 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EFNB2 | ephrin-B2 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| ETV4 | ets variant 4 |
| F10 | coagulation factor X |
| FAAH | fatty acid amide hydrolase |
| FAM60A | family with sequence similarity 60, member A |
| FBXO8 | F-box protein 8 |
| FOXN3 | forkhead box N3 |
| FZD7 | frizzled class receptor 7 |
| G0S2 | G0/G1 switch 2 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
| GBP4 | guanylate binding protein 4 |
| GFAP | glial fibrillary acidic protein |
| GGNBP1 | gametogenetin binding protein 1 (pseudogene) |
| GPATCH2 | G patch domain containing 2 |
| GPX3 | glutathione peroxidase 3 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HDGFL1 | hepatoma derived growth factor-like 1 |
| HES3 | hes family bHLH transcription factor 3 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXB5 | homeobox B5 |
| HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF7 | interferon regulatory factor 7 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNA2 | potassium channel, voltage gated shaker related subfamily A, member 2 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNA4 | potassium channel, voltage gated shaker related subfamily A, member 4 |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KITLG | KIT ligand |
| KRT6B | keratin 6B, type II |
| KRTAP3-1 | keratin associated protein 3-1 |
| LAMA1 | laminin, alpha 1 |
| LBP | lipopolysaccharide binding protein |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHB | luteinizing hormone beta polypeptide |
| LHX1 | LIM homeobox 1 |
| LSR | lipolysis stimulated lipoprotein receptor |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MMP3 | matrix metallopeptidase 3 |
| MRAP | melanocortin 2 receptor accessory protein |
| MYOG | myogenin (myogenic factor 4) |
| NAGK | N-acetylglucosamine kinase |
| NCOA2 | nuclear receptor coactivator 2 |
| NEO1 | neogenin 1 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| NGEF | neuronal guanine nucleotide exchange factor |
| NGF | nerve growth factor (beta polypeptide) |
| NMT2 | N-myristoyltransferase 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NT5DC2 | 5'-nucleotidase domain containing 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OCLN | occludin |
| OLFM1 | olfactomedin 1 |
| PCDH7 | protocadherin 7 |
| PCDHA10 | protocadherin alpha 10 |
| PCP2 | Purkinje cell protein 2 |
| PHOSPHO2 | phosphatase, orphan 2 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G10 | phospholipase A2, group X |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLXNA1 | plexin A1 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRH1 | proline-rich protein HaeIII subfamily 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| RAI2 | retinoic acid induced 2 |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 |
| RASD1 | RAS, dexamethasone-induced 1 |
| RSPH1 | radial spoke head 1 homolog (Chlamydomonas) |
| SDSL | serine dehydratase-like |
| SEPT6 | septin 6 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SH2D2A | SH2 domain containing 2A |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| SLC22A18 | solute carrier family 22, member 18 |
| SPRR2B | small proline-rich protein 2B |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| ST6GALNAC6 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 |
| STC1 | stanniocalcin 1 |
| STK11IP | serine/threonine kinase 11 interacting protein |
| SYNGR4 | synaptogyrin 4 |
| SYT11 | synaptotagmin XI |
| SYT8 | synaptotagmin VIII |
| TAL2 | T-cell acute lymphocytic leukemia 2 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| TBXA2R | thromboxane A2 receptor |
| TFR2 | transferrin receptor 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| THBD | thrombomodulin |
| TLR6 | toll-like receptor 6 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNNI3 | troponin I type 3 (cardiac) |
| TRAPPC5 | trafficking protein particle complex 5 |
| TSHB | thyroid stimulating hormone, beta |
| TSPAN5 | tetraspanin 5 |
| TUSC2 | tumor suppressor candidate 2 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 |
| USP18 | ubiquitin specific peptidase 18 |
| VEGFA | vascular endothelial growth factor A |
| VIM | vimentin |
| VPREB1 | pre-B lymphocyte 1 |
| VWA7 | von Willebrand factor A domain containing 7 |
