WT1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Wilms tumor 1|This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015] (NCBI Entrez Gene Database, 7490)
External Link https://ncbi.nlm.nih.gov/gene/7490
Similar Terms
Downloads & Tools

Genes

499 genes differentially expressed following the WT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0236753
VCAM1 vascular cell adhesion molecule 1 0.0137818
NNMT nicotinamide N-methyltransferase 0.0110364
ADIRF adipogenesis regulatory factor 0.00968869
QDPR quinoid dihydropteridine reductase 0.00950346
GPR137B G protein-coupled receptor 137B 0.00944556
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00913283
CCL19 chemokine (C-C motif) ligand 19 0.00910527
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00902935
MT1F metallothionein 1F 0.00896827
TOB1 transducer of ERBB2, 1 0.0088886
CLU clusterin 0.008855
ALCAM activated leukocyte cell adhesion molecule 0.00874185
UGCG UDP-glucose ceramide glucosyltransferase 0.00847881
HOXC6 homeobox C6 0.00833978
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00833386
MT1X metallothionein 1X 0.00823146
CXCL14 chemokine (C-X-C motif) ligand 14 0.00812849
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00797258
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 0.00796108
SLC38A1 solute carrier family 38, member 1 0.00793269
TXNDC9 thioredoxin domain containing 9 0.00782068
MT1E metallothionein 1E 0.00780542
ARG1 arginase 1 0.00770338
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.0076569
GOLT1B golgi transport 1B 0.00751586
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00744159
SCGB2A2 secretoglobin, family 2A, member 2 0.00739484
DNASE1L3 deoxyribonuclease I-like 3 0.00738152
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00727793
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00722446
RPS27L ribosomal protein S27-like 0.00717904
MT1G metallothionein 1G 0.00707918
MT1H metallothionein 1H 0.00706539
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00705653
PHF20 PHD finger protein 20 0.00701899
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.00701735
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00700109
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00691999
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00690021
CPVL carboxypeptidase, vitellogenic-like 0.00689509
CHPT1 choline phosphotransferase 1 0.00688619
SATB2 SATB homeobox 2 0.00680159
RRAGC Ras-related GTP binding C 0.00678243
CLGN calmegin 0.00675926
HTRA1 HtrA serine peptidase 1 0.00674819
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00674075
MMP9 matrix metallopeptidase 9 0.0067327
TPSAB1 tryptase alpha/beta 1 0.00672198
CXCL9 chemokine (C-X-C motif) ligand 9 0.00664118
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00657729
CLC Charcot-Leyden crystal galectin 0.00651938
TOX3 TOX high mobility group box family member 3 0.00650595
ZBTB38 zinc finger and BTB domain containing 38 0.00648388
PRSS8 protease, serine, 8 0.00648359
ATP5F1E ATP synthase F1 subunit epsilon 0.00645616
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00642835
QPCT glutaminyl-peptide cyclotransferase 0.00641158
MCUR1 mitochondrial calcium uniporter regulator 1 0.00640829
ANPEP alanyl (membrane) aminopeptidase 0.00638751
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00638729
RPA3 replication protein A3, 14kDa 0.00637391
SRGN serglycin 0.00634514
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00632334
BANP BTG3 associated nuclear protein 0.00632266
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00631735
CCL21 chemokine (C-C motif) ligand 21 0.00625813
PDPK1 3-phosphoinositide dependent protein kinase 1 0.00624057
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00623867
GLOD4 glyoxalase domain containing 4 0.00622598
MT1HL1 metallothionein 1H-like 1 0.00618888
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00616395
INTS6 integrator complex subunit 6 0.00613812
EPHB2 EPH receptor B2 0.00613291
SKAP2 src kinase associated phosphoprotein 2 0.00611391
FGFR3 fibroblast growth factor receptor 3 0.00611114
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00610414
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00610334
TM9SF3 transmembrane 9 superfamily member 3 0.00609894
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00607262
FAM162A family with sequence similarity 162, member A 0.00607086
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0060672
IL7R interleukin 7 receptor 0.00606338
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00605262
HPCAL1 hippocalcin-like 1 0.00603394
GSK3B glycogen synthase kinase 3 beta 0.0060206
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00601695
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00601259
FABP1 fatty acid binding protein 1, liver 0.00601042
HIST1H2BD histone cluster 1, H2bd 0.00597574
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.00597039
MFAP3L microfibrillar-associated protein 3-like 0.00596926
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.00595874
CXCL12 chemokine (C-X-C motif) ligand 12 0.00590359
MPC1 mitochondrial pyruvate carrier 1 0.00586423
FKBP14 FK506 binding protein 14, 22 kDa 0.0058568
DEFA4 defensin, alpha 4, corticostatin 0.00585157
CTSA cathepsin A 0.00582865
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00580181
GREM1 gremlin 1, DAN family BMP antagonist 0.00579172
ACAT2 acetyl-CoA acetyltransferase 2 0.00578088
SEPHS2 selenophosphate synthetase 2 0.00577171
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.00575606
BRD2 bromodomain containing 2 0.00572674
HOXC10 homeobox C10 0.00572393
TEX30 testis expressed 30 0.00565262
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00561274
ZNF91 zinc finger protein 91 0.00555248
TPP1 tripeptidyl peptidase I 0.00553496
AMDHD2 amidohydrolase domain containing 2 0.00553038
APMAP adipocyte plasma membrane associated protein 0.00552937
CCL15 chemokine (C-C motif) ligand 15 0.0055264
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.00550171
FXYD2 FXYD domain containing ion transport regulator 2 0.00549689
GLYAT glycine-N-acyltransferase 0.00549251
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00544962
LAGE3 L antigen family, member 3 0.00544816
PTER phosphotriesterase related 0.00544467
EXOSC4 exosome component 4 0.00543587
SLC46A3 solute carrier family 46, member 3 0.0054223
SGK1 serum/glucocorticoid regulated kinase 1 0.00541604
SIKE1 suppressor of IKBKE 1 0.00541391
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00540302
C12ORF29 chromosome 12 open reading frame 29 0.00539651
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00538876
CA12 carbonic anhydrase XII 0.00538095
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00537693
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00537656
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.00537478
GLIPR1 GLI pathogenesis-related 1 0.0053613
GSTO1 glutathione S-transferase omega 1 0.00535412
CXCL6 chemokine (C-X-C motif) ligand 6 0.00534426
NUP58 nucleoporin 58 0.00534255
TMEM106B transmembrane protein 106B 0.0053418
OSBPL8 oxysterol binding protein-like 8 0.00532282
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00532155
TRIM8 tripartite motif containing 8 0.00531913
SEC62 SEC62 homolog (S. cerevisiae) 0.00531569
NOTCH2NL notch 2 N-terminal like 0.00530603
PDZK1 PDZ domain containing 1 0.00530079
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00528636
IRX5 iroquois homeobox 5 0.00528309
NOAZFP nucleolar atypical zinc finger 0.0052743
NINJ2 ninjurin 2 0.00526552
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.00522726
FTH1 ferritin, heavy polypeptide 1 0.00522329
NPC2 Niemann-Pick disease, type C2 0.00521876
KIAA0355 KIAA0355 0.00521833
CTSG cathepsin G 0.00521147
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.00520743
SLC44A4 solute carrier family 44, member 4 0.00520353
ITGAV integrin, alpha V 0.00520292
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00518561
EVA1B eva-1 homolog B (C. elegans) 0.0051791
PIPOX pipecolic acid oxidase 0.00516248
JADE1 jade family PHD finger 1 0.00515419
ADH6 alcohol dehydrogenase 6 (class V) 0.00513907
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00513869
CTSW cathepsin W 0.00512171
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00511479
WASL Wiskott-Aldrich syndrome-like 0.00508088
LYRM1 LYR motif containing 1 0.00506686
RAP1GAP2 RAP1 GTPase activating protein 2 0.00505218
NPY neuropeptide Y 0.00504803
BTG1 B-cell translocation gene 1, anti-proliferative 0.00503987
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.00502978
SOX9 SRY (sex determining region Y)-box 9 0.00502483
PF4 platelet factor 4 0.00501574
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00500541
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00500317
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.0050019
SFXN3 sideroflexin 3 0.00499563
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00498225
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00498095
ATP5ME ATP synthase membrane subunit e 0.00496655
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 0.00496178
COMMD8 COMM domain containing 8 0.00494715
SHLD2 shieldin complex subunit 2 0.00493603
GSTM3 glutathione S-transferase mu 3 (brain) 0.00493201
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00490192
DYNLRB1 dynein, light chain, roadblock-type 1 0.00488736
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00488674
HBB hemoglobin, beta 0.0048772
DEF8 differentially expressed in FDCP 8 homolog (mouse) 0.00486574
TYRP1 tyrosinase-related protein 1 0.00485834
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.00485341
CRP C-reactive protein, pentraxin-related 0.00485225
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00485184
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.00484458
RAPSN receptor-associated protein of the synapse 0.00483655
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00483635
LIPC lipase, hepatic 0.00483497
MT2A metallothionein 2A 0.004783
GLUD1 glutamate dehydrogenase 1 0.00477669
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00477203
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00477163
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00475401
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.00475174
FAM171A1 family with sequence similarity 171, member A1 0.00474436
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00473903
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00473124
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00472787
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00472681
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.00472178
PLXNC1 plexin C1 0.0047143
PRSS3 protease, serine, 3 0.00471244
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.00470906
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00470602
TYROBP TYRO protein tyrosine kinase binding protein 0.00467969
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00467936
ALDOB aldolase B, fructose-bisphosphate 0.004677
RWDD1 RWD domain containing 1 0.00467143
IPCEF1 interaction protein for cytohesin exchange factors 1 0.00466914
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00466646
CLCN7 chloride channel, voltage-sensitive 7 0.00466324
WASHC3 WASH complex subunit 3 0.00465987
LOC283683 uncharacterized LOC283683 0.00464466
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.00464087
SMAD2 SMAD family member 2 0.00463695
ELOVL1 ELOVL fatty acid elongase 1 0.00462904
PTK2B protein tyrosine kinase 2 beta 0.0046284
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00462624
CCDC92 coiled-coil domain containing 92 0.00461727
HAUS3 HAUS augmin-like complex, subunit 3 0.00460827
COMP cartilage oligomeric matrix protein 0.00459938
ERGIC2 ERGIC and golgi 2 0.00459071
CTBS chitobiase, di-N-acetyl- 0.00458202
TSC22D1 TSC22 domain family, member 1 0.0045761
PXDC1 PX domain containing 1 0.00456611
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.0045603
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00454533
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 0.00454248
SCAND1 SCAN domain containing 1 0.00454178
AMACR alpha-methylacyl-CoA racemase 0.00453651
CRIP1 cysteine-rich protein 1 (intestinal) 0.00453487
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00452732
KRT10 keratin 10, type I 0.00452712
TECR trans-2,3-enoyl-CoA reductase 0.00452229
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.00451601
GCAT glycine C-acetyltransferase 0.00451271
HP haptoglobin 0.00450946
LONP2 lon peptidase 2, peroxisomal 0.0045015
BBX bobby sox homolog (Drosophila) 0.00449561
DPEP1 dipeptidase 1 (renal) 0.00449275
EMC7 ER membrane protein complex subunit 7 0.00448199
TSPAN13 tetraspanin 13 0.00447693
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00447217
GNAS GNAS complex locus 0.00446082
CMC2 C-x(9)-C motif containing 2 0.00445622

decreased expression

Symbol Name Standardized Value
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0148086
MYBPC1 myosin binding protein C, slow type -0.0135818
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0127915
TNNC1 troponin C type 1 (slow) -0.0127526
TTN titin -0.0118101
CAV1 caveolin 1, caveolae protein, 22kDa -0.0117022
DMD dystrophin -0.0113478
XIC X chromosome inactivation center -0.0108952
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.0107787
ACTA1 actin, alpha 1, skeletal muscle -0.0106132
DES desmin -0.0104973
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0103971
DLK1 delta-like 1 homolog (Drosophila) -0.0101157
POSTN periostin, osteoblast specific factor -0.0100805
COLEC12 collectin sub-family member 12 -0.00995482
SIRT3 sirtuin 3 -0.00993179
FHL1 four and a half LIM domains 1 -0.0097614
FABP4 fatty acid binding protein 4, adipocyte -0.00974623
KRT13 keratin 13, type I -0.00972437
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00958105
TNNC2 troponin C type 2 (fast) -0.00956396
KLHL41 kelch-like family member 41 -0.00949118
COL1A2 collagen, type I, alpha 2 -0.00946345
FHOD3 formin homology 2 domain containing 3 -0.00939301
COL15A1 collagen, type XV, alpha 1 -0.00937524
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00916599
MEIS2 Meis homeobox 2 -0.00911259
PEG10 paternally expressed 10 -0.00903798
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0090207
MYOT myotilin -0.0087799
FBLN1 fibulin 1 -0.00869015
MB myoglobin -0.00855427
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.008549
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00854662
PAM peptidylglycine alpha-amidating monooxygenase -0.00853468
CKM creatine kinase, muscle -0.00838244
EMP1 epithelial membrane protein 1 -0.00837335
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00835289
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00832916
LPAR6 lysophosphatidic acid receptor 6 -0.00832533
ACTC1 actin, alpha, cardiac muscle 1 -0.0082582
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.008165
SFRP1 secreted frizzled-related protein 1 -0.00815791
MAOA monoamine oxidase A -0.00809014
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00807952
ADM adrenomedullin -0.00806956
NID1 nidogen 1 -0.00804579
COL4A5 collagen, type IV, alpha 5 -0.00804144
PTN pleiotrophin -0.00791804
P3H2 prolyl 3-hydroxylase 2 -0.00790044
FXYD3 FXYD domain containing ion transport regulator 3 -0.00788878
TPM3 tropomyosin 3 -0.00771882
COG7 component of oligomeric golgi complex 7 -0.0077016
A2M alpha-2-macroglobulin -0.00761667
MDK midkine (neurite growth-promoting factor 2) -0.00761116
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00760187
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00753164
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00749863
SLN sarcolipin -0.00745835
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00741192
RTN2 reticulon 2 -0.00735105
SMPX small muscle protein, X-linked -0.00735097
MYOF myoferlin -0.00733424
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00731715
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00729921
PGD phosphogluconate dehydrogenase -0.00727025
SVIL supervillin -0.00723644
FXYD6 FXYD domain containing ion transport regulator 6 -0.00722997
ANXA2 annexin A2 -0.00721509
NELL2 NEL-like 2 (chicken) -0.00718696
YBX3 Y box binding protein 3 -0.0071811
DCHS1 dachsous cadherin-related 1 -0.00716429
MGP matrix Gla protein -0.00715543
TSPAN7 tetraspanin 7 -0.00715345
LAMA4 laminin, alpha 4 -0.00712927
SCD5 stearoyl-CoA desaturase 5 -0.00709811
ADGRL2 adhesion G protein-coupled receptor L2 -0.00709205
CA3 carbonic anhydrase III -0.00709066
PEG3 paternally expressed 3 -0.00707727
LY6D lymphocyte antigen 6 complex, locus D -0.00704052
HSPB8 heat shock 22kDa protein 8 -0.00703824
C3 complement component 3 -0.00699172
KRT19 keratin 19, type I -0.00695769
NES nestin -0.00690447
COL6A3 collagen, type VI, alpha 3 -0.0068522
MSMB microseminoprotein, beta- -0.00682136
PALMD palmdelphin -0.00679945
FCGBP Fc fragment of IgG binding protein -0.00679232
GPC3 glypican 3 -0.00678429
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -0.00678219
FGFBP1 fibroblast growth factor binding protein 1 -0.00675087
EGR2 early growth response 2 -0.00674593
COL4A6 collagen, type IV, alpha 6 -0.00673996
DENND2B DENN domain containing 2B -0.00673361
GRK5 G protein-coupled receptor kinase 5 -0.00671066
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00667492
NIBAN1 niban apoptosis regulator 1 -0.00666908
VWF von Willebrand factor -0.0066582
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00664242
ATF4 activating transcription factor 4 -0.00662949
DAPK1 death-associated protein kinase 1 -0.00661308
NCAM1 neural cell adhesion molecule 1 -0.00661042
FAM189A2 family with sequence similarity 189, member A2 -0.00660414
TNNI1 troponin I type 1 (skeletal, slow) -0.00660345
THBS4 thrombospondin 4 -0.00659957
TNNI2 troponin I type 2 (skeletal, fast) -0.00659829
COL3A1 collagen, type III, alpha 1 -0.00658454
MTUS1 microtubule associated tumor suppressor 1 -0.00658049
INHBB inhibin, beta B -0.0065731
RGS5 regulator of G-protein signaling 5 -0.0065645
MYH11 myosin, heavy chain 11, smooth muscle -0.00656169
OPHN1 oligophrenin 1 -0.00655544
SORBS1 sorbin and SH3 domain containing 1 -0.00653517
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00652551
EGR1 early growth response 1 -0.00651204
MPZL2 myelin protein zero-like 2 -0.00650041
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00648419
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00648184
SPRR3 small proline-rich protein 3 -0.00647251
FN1 fibronectin 1 -0.0064645
TPM2 tropomyosin 2 (beta) -0.00645456
TNS1 tensin 1 -0.00644842
SNX7 sorting nexin 7 -0.00642895
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00640763
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00640706
IL32 interleukin 32 -0.00633212
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -0.00632109
F3 coagulation factor III (thromboplastin, tissue factor) -0.0063125
OLFML2A olfactomedin-like 2A -0.00630355
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00629964
SYNM synemin, intermediate filament protein -0.00629403
COL5A2 collagen, type V, alpha 2 -0.00628837
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00625045
MRPS16 mitochondrial ribosomal protein S16 -0.00621626
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00620522
IL27RA interleukin 27 receptor, alpha -0.00620459
IFRD2 interferon-related developmental regulator 2 -0.0062005
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00618758
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00618645
ARG2 arginase 2 -0.00618528
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -0.00615333
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0061327
RGCC regulator of cell cycle -0.00611016
CASQ2 calsequestrin 2 (cardiac muscle) -0.00610392
RTN1 reticulon 1 -0.00610317
PYGM phosphorylase, glycogen, muscle -0.00609823
TGFA transforming growth factor, alpha -0.00606511
SEPTIN10 septin 10 -0.0060506
LMOD1 leiomodin 1 (smooth muscle) -0.00603411
KIF5C kinesin family member 5C -0.00602748
MYOZ2 myozenin 2 -0.00602062
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.0060046
PTPRE protein tyrosine phosphatase, receptor type, E -0.00599786
ASS1 argininosuccinate synthase 1 -0.00597002
SSPN sarcospan -0.00596336
GRP gastrin-releasing peptide -0.00595883
AKR1C2 aldo-keto reductase family 1, member C2 -0.00591952
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00589797
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00588906
SALL2 spalt-like transcription factor 2 -0.00585097
MYBPC2 myosin binding protein C, fast type -0.00584472
COL21A1 collagen, type XXI, alpha 1 -0.00583189
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00582713
PBX1 pre-B-cell leukemia homeobox 1 -0.00580148
INAVA innate immunity activator -0.00579324
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00579178
ACTN2 actinin, alpha 2 -0.00579147
SPARCL1 SPARC-like 1 (hevin) -0.00578785
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00578113
PPARG peroxisome proliferator-activated receptor gamma -0.00577715
MYOZ1 myozenin 1 -0.00576828
OGN osteoglycin -0.00571143
FLI1 Fli-1 proto-oncogene, ETS transcription factor -0.00571114
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00570995
FBN2 fibrillin 2 -0.00570749
IFT57 intraflagellar transport 57 -0.00570336
IPW imprinted in Prader-Willi syndrome (non-protein coding) -0.00569233
CAV2 caveolin 2 -0.00565285
PADI2 peptidyl arginine deiminase, type II -0.00565267
LHFP lipoma HMGIC fusion partner -0.0056221
FMO2 flavin containing monooxygenase 2 (non-functional) -0.0056132
GIMAP4 GTPase, IMAP family member 4 -0.00557088
TRIB3 tribbles pseudokinase 3 -0.00556514
ETHE1 ethylmalonic encephalopathy 1 -0.0055569
TRIM16 tripartite motif containing 16 -0.00554944
STON1 stonin 1 -0.00554491
PLN phospholamban -0.0055217
CD200 CD200 molecule -0.00551564
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00551318
CHI3L2 chitinase 3-like 2 -0.00547059
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00545824
DLG5 discs, large homolog 5 (Drosophila) -0.00542866
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0054218
PHC1 polyhomeotic homolog 1 (Drosophila) -0.00541474
HSPB3 heat shock 27kDa protein 3 -0.00540865
PDLIM3 PDZ and LIM domain 3 -0.005386
HSPB6 heat shock protein, alpha-crystallin-related, B6 -0.00538459
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -0.00538368
TSPAN8 tetraspanin 8 -0.0053833
JPT1 Jupiter microtubule associated homolog 1 -0.00538212
IGSF3 immunoglobulin superfamily, member 3 -0.00536024
CCNB1 cyclin B1 -0.00535947
DTX4 deltex 4, E3 ubiquitin ligase -0.00535746
TMC5 transmembrane channel-like 5 -0.005347
RAB15 RAB15, member RAS oncogene family -0.00533672
MFAP4 microfibrillar-associated protein 4 -0.0053269
SNAP25 synaptosomal-associated protein, 25kDa -0.00530375
KRT15 keratin 15, type I -0.00530078
AUH AU RNA binding protein/enoyl-CoA hydratase -0.00528028
GYS1 glycogen synthase 1 (muscle) -0.0052688
ANXA1 annexin A1 -0.00526569
AOC3 amine oxidase, copper containing 3 -0.00525948
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.00525624
PDE4B phosphodiesterase 4B, cAMP-specific -0.00525375
MYH7 myosin, heavy chain 7, cardiac muscle, beta -0.00524965
KDM6A lysine (K)-specific demethylase 6A -0.00523613
ACTB actin, beta -0.00523164
CHRDL1 chordin-like 1 -0.00523121
TUBB2A tubulin, beta 2A class IIa -0.00522474
RNPEP arginyl aminopeptidase (aminopeptidase B) -0.00520759
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00520658
AKAP12 A kinase (PRKA) anchor protein 12 -0.00519426
PADI3 peptidyl arginine deiminase, type III -0.00518399
ADAM22 ADAM metallopeptidase domain 22 -0.00518376
FILIP1L filamin A interacting protein 1-like -0.00517878
AMPD1 adenosine monophosphate deaminase 1 -0.00517281
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) -0.00516367
MTMR11 myotubularin related protein 11 -0.0051632
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -0.00515701
NUSAP1 nucleolar and spindle associated protein 1 -0.00515312
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.00512666
KRT17 keratin 17, type I -0.0051264
AGTPBP1 ATP/GTP binding protein 1 -0.00511332
OAZ1 ornithine decarboxylase antizyme 1 -0.00511207
RXRA retinoid X receptor, alpha -0.00509824
TMEM255A transmembrane protein 255A -0.00509687
MTA1 metastasis associated 1 -0.00508545
ZFPM2 zinc finger protein, FOG family member 2 -0.00508276
TAGLN transgelin -0.00508101
CASD1 CAS1 domain containing 1 -0.00505958
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.00502869
DLD dihydrolipoamide dehydrogenase -0.00502084
FMOD fibromodulin -0.00500778
CNN1 calponin 1, basic, smooth muscle -0.00497786
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -0.00497503
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -0.00495683
SOX11 SRY (sex determining region Y)-box 11 -0.00493537
RAB25 RAB25, member RAS oncogene family -0.0049298
SAMD9 sterile alpha motif domain containing 9 -0.00492362
MDFIC MyoD family inhibitor domain containing -0.00491674