WWTR1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description WW domain containing transcription regulator 1| (NCBI Entrez Gene Database, 25937)
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Genes

306 genes differentially expressed following the WWTR1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMEM212 transmembrane protein 212 2.19063
GLUD2 glutamate dehydrogenase 2 2.19063
PDYN prodynorphin 2.19063
PRODH2 proline dehydrogenase (oxidase) 2 2.19063
WNT3A wingless-type MMTV integration site family, member 3A 2.19063
GRXCR2 glutaredoxin, cysteine rich 2 2.19063
ELSPBP1 epididymal sperm binding protein 1 2.19063
AADACL3 arylacetamide deacetylase-like 3 2.19063
CSTL1 cystatin-like 1 2.19063
PAX4 paired box 4 2.19063
C1ORF115 chromosome 1 open reading frame 115 2.19063
ADRB2 adrenoceptor beta 2, surface 2.19063
BTC betacellulin 2.19063
FOLR1 folate receptor 1 (adult) 2.19063
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.19063
FGF23 fibroblast growth factor 23 2.19063
TNRC6C trinucleotide repeat containing 6C 2.19063
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.19063
DUXB double homeobox B 2.19063
IZUMO3 IZUMO family member 3 2.19063
IGFL2 IGF-like family member 2 2.19063
OR52A5 olfactory receptor, family 52, subfamily A, member 5 2.19063
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.19063
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 2.19063
OLFM4 olfactomedin 4 2.19063
CRYGN crystallin, gamma N 2.19063
ATOH1 atonal homolog 1 (Drosophila) 2.19063
ATOH7 atonal homolog 7 (Drosophila) 2.19063
DIO1 deiodinase, iodothyronine, type I 2.19063
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 2.19063
RNF133 ring finger protein 133 2.19063
TMC8 transmembrane channel-like 8 2.19063
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 2.19063
RNF39 ring finger protein 39 2.19063
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.19063
TMEM121 transmembrane protein 121 2.19063
ANKK1 ankyrin repeat and kinase domain containing 1 2.19063
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.19063
RFPL2 ret finger protein-like 2 2.19063
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 2.19063
SUSD2 sushi domain containing 2 2.19063
ADAMTSL5 ADAMTS-like 5 2.19063
TPSD1 tryptase delta 1 2.19063
DEFB124 defensin, beta 124 2.19063
C1ORF141 chromosome 1 open reading frame 141 2.19063
OCSTAMP osteoclast stimulatory transmembrane protein 2.19063
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 2.19063
CPNE8-AS1 CPNE8 antisense RNA 1 2.19063
FMO1 flavin containing monooxygenase 1 2.19063
TMPRSS4 transmembrane protease, serine 4 2.19063
RPL21 ribosomal protein L21 2.19063
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.19063
ASB5 ankyrin repeat and SOCS box containing 5 2.19063
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.19063
LMTK1 lemur tail kinase 1 2.19063
FAM228A family with sequence similarity 228, member A 2.19063
THSD8 thrombospondin type 1 domain containing 8 2.19063
STX11 syntaxin 11 2.19063
GPR31 G protein-coupled receptor 31 2.19063
CLDN16 claudin 16 2.19063
SAXO4 stabilizer of axonemal microtubules 4 2.19063
NOTCH2NLB notch 2 N-terminal like B 2.19063
SERTM2 serine rich and transmembrane domain containing 2 2.19063
MEIOSIN meiosis initiator 2.19063
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 2.19063
SMIM41 small integral membrane protein 41 2.19063
SEPTIN3 septin 3 2.19063
ROPN1L rhophilin associated tail protein 1-like 2.19063
BRIX1 BRX1, biogenesis of ribosomes 2.19063
CSAG1 chondrosarcoma associated gene 1 2.19063
TUBA4B tubulin, alpha 4b 2.19063
SOAT2 sterol O-acyltransferase 2 2.19063
CLDN9 claudin 9 2.19063
C1ORF87 chromosome 1 open reading frame 87 2.19063
PCDHB13 protocadherin beta 13 2.19063
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.19063
RPS15 ribosomal protein S15 2.19063
CAPN12 calpain 12 2.19063
PVRIG poliovirus receptor related immunoglobulin domain containing 2.19063
TAS2R5 taste receptor, type 2, member 5 2.19063
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.19063
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.19063
ANXA13 annexin A13 2.19063
PTP4A1 protein tyrosine phosphatase type IVA, member 1 2.19063
SBSN suprabasin 2.19063
EXOC3L1 exocyst complex component 3-like 1 2.19063
GJD3 gap junction protein, delta 3, 31.9kDa 2.19063
TCF23 transcription factor 23 2.19063
C1QTNF7 C1q and tumor necrosis factor related protein 7 2.19063
TBX3 T-box 3 2.19063
PRKCI protein kinase C, iota 2.19063
DMBX1 diencephalon/mesencephalon homeobox 1 2.19063
CXCL11 chemokine (C-X-C motif) ligand 11 2.19063
NDRG1 N-myc downstream regulated 1 2.19063
OR56A5 olfactory receptor, family 56, subfamily A, member 5 2.19063
SPRN shadow of prion protein homolog (zebrafish) 2.19063
ERVV-2 endogenous retrovirus group V, member 2 2.19063
CST4 cystatin S 2.19063
CST7 cystatin F (leukocystatin) 2.19063
UBQLNL ubiquilin-like 2.19063
LDLRAD1 low density lipoprotein receptor class A domain containing 1 2.19063
TNR tenascin R 2.19063
LHX5 LIM homeobox 5 2.19063
FATE1 fetal and adult testis expressed 1 2.19063
ZNF541 zinc finger protein 541 2.19063
NXNL1 nucleoredoxin-like 1 2.19063
CNTF ciliary neurotrophic factor 2.19063
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.19063
STAB2 stabilin 2 2.19063
PCDHGB1 protocadherin gamma subfamily B, 1 2.19063
PCDHGB2 protocadherin gamma subfamily B, 2 2.19063
PALMD palmdelphin 2.19063
CCL27 chemokine (C-C motif) ligand 27 2.19063
TMEM132E transmembrane protein 132E 2.19063
MR1 major histocompatibility complex, class I-related 2.19063
ANKRD60 ankyrin repeat domain 60 2.19063
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.19063
ZCCHC18 zinc finger, CCHC domain containing 18 2.19063
PDZRN4 PDZ domain containing ring finger 4 2.19063
CATIP ciliogenesis associated TTC17 interacting protein 2.19063
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.19063
UTS2B urotensin 2B 2.19063
NT5C1B 5'-nucleotidase, cytosolic IB 2.19063
RPL7A ribosomal protein L7a 2.19063
CFAP126 cilia and flagella associated protein 126 2.19063
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.19063
PCDHGA1 protocadherin gamma subfamily A, 1 2.19063
DRD2 dopamine receptor D2 2.19063
KLF1 Kruppel-like factor 1 (erythroid) 2.19063
ZNF625 zinc finger protein 625 2.19063
ADAM7 ADAM metallopeptidase domain 7 2.19063
PGR progesterone receptor 2.19063
CPA3 carboxypeptidase A3 (mast cell) 2.19063
NOBOX NOBOX oogenesis homeobox 2.19063
GPR61 G protein-coupled receptor 61 2.19063
KCTD21 potassium channel tetramerization domain containing 21 2.19063
SIGLEC15 sialic acid binding Ig-like lectin 15 2.19063
WDR76 WD repeat domain 76 2.19063
TPRX1 tetra-peptide repeat homeobox 1 2.19063
TMEM215 transmembrane protein 215 2.19063
SERINC3 serine incorporator 3 2.19063
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.19063
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 2.19063
KCTD4 potassium channel tetramerization domain containing 4 2.19063
ANXA8 annexin A8 2.19063
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.19063
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.19063
IL33 interleukin 33 2.19063
LPO lactoperoxidase 2.19063
ASCL2 achaete-scute family bHLH transcription factor 2 2.19063
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 2.19063
TPO thyroid peroxidase 2.19063
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.19063
ZNF804A zinc finger protein 804A 2.19063
DCST1 DC-STAMP domain containing 1 2.19063
VPREB3 pre-B lymphocyte 3 2.19063
IQSEC3 IQ motif and Sec7 domain 3 2.19063
TMEM87B transmembrane protein 87B 2.19063
ALLC allantoicase 2.19063
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 2.19063
LAMP3 lysosomal-associated membrane protein 3 2.19063
TMEM86B transmembrane protein 86B 2.19063
OR11G2 olfactory receptor, family 11, subfamily G, member 2 2.19063
RNF223 ring finger protein 223 2.19063
CHRM1 cholinergic receptor, muscarinic 1 2.19063
ACTB actin, beta 2.19063
ADGRF5 adhesion G protein-coupled receptor F5 2.19063
C9ORF57 chromosome 9 open reading frame 57 2.19063
GLIPR1 GLI pathogenesis-related 1 2.19063
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3 2.19063
ZBED6 zinc finger, BED-type containing 6 2.19063
TMEM156 transmembrane protein 156 2.19063
FOXS1 forkhead box S1 2.19063
ZNF835 zinc finger protein 835 2.19063
DMRTC1 DMRT-like family C1 2.19063
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.19063
CCDC78 coiled-coil domain containing 78 2.19063
PRAP1 proline-rich acidic protein 1 2.19063
PPY pancreatic polypeptide 2.19063
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.19063
OPN3 opsin 3 2.18704
D2HGDH D-2-hydroxyglutarate dehydrogenase 2.17283
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 2.16275
PEX6 peroxisomal biogenesis factor 6 2.13084
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.12623
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10 2.0945
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 2.0945
TSSK3 testis-specific serine kinase 3 2.0945
IGSF22 immunoglobulin superfamily, member 22 2.0945
IRGQ immunity-related GTPase family, Q 2.08882
BAG6 BCL2-associated athanogene 6 2.07133
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2.07133
FBXW9 F-box and WD repeat domain containing 9 2.06132
DPPA4 developmental pluripotency associated 4 2.06132
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 2.06132
AFF3 AF4/FMR2 family, member 3 2.06132
RPL34 ribosomal protein L34 2.06132
ANAPC11 anaphase promoting complex subunit 11 2.06132
TMEM258 transmembrane protein 258 2.03413
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.03413
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.03413
MAOB monoamine oxidase B 2.02644
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 2.02363
DISP1 dispatched homolog 1 (Drosophila) 2.01386
CTSC cathepsin C 2.01113
F8A1 coagulation factor VIII-associated 1 2.00068

decreased expression

Symbol Name Standardized Value
TMSB15C thymosin beta 15C -2.19063
LMO2 LIM domain only 2 (rhombotin-like 1) -2.19063
GHRL ghrelin/obestatin prepropeptide -2.19063
LRPPRC leucine-rich pentatricopeptide repeat containing -2.19063
CA3 carbonic anhydrase III -2.19063
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.19063
WWTR1 WW domain containing transcription regulator 1 -2.19063
MROH6 maestro heat-like repeat family member 6 -2.19063
TBC1D5 TBC1 domain family, member 5 -2.19063
SLC67A1 solute carrier family 67 member 1 -2.19063
ACAT1 acetyl-CoA acetyltransferase 1 -2.19063
TLN2 talin 2 -2.19063
LY6G5B lymphocyte antigen 6 complex, locus G5B -2.19063
TICAM1 toll-like receptor adaptor molecule 1 -2.19063
PUS3 pseudouridylate synthase 3 -2.19063
WTAP Wilms tumor 1 associated protein -2.19063
ZNF814 zinc finger protein 814 -2.19063
MINAR1 membrane integral NOTCH2 associated receptor 1 -2.19063
CAPN5 calpain 5 -2.19063
HTRA3 HtrA serine peptidase 3 -2.19063
ZMYM5 zinc finger, MYM-type 5 -2.19063
ZNF680 zinc finger protein 680 -2.19063
PPME1 protein phosphatase methylesterase 1 -2.19063
IL27RA interleukin 27 receptor, alpha -2.19063
ANKIB1 ankyrin repeat and IBR domain containing 1 -2.19063
ACHE acetylcholinesterase (Yt blood group) -2.19063
CRYM crystallin, mu -2.19063
RENBP renin binding protein -2.19063
PLIN5 perilipin 5 -2.19063
ZNF469 zinc finger protein 469 -2.19063
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) -2.19063
VMAC vimentin-type intermediate filament associated coiled-coil protein -2.19063
KPNA5 karyopherin alpha 5 (importin alpha 6) -2.19063
RNFT1 ring finger protein, transmembrane 1 -2.19063
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.19063
RND1 Rho family GTPase 1 -2.19063
CUX2 cut-like homeobox 2 -2.19063
RAB40C RAB40C, member RAS oncogene family -2.19063
CHMP4B charged multivesicular body protein 4B -2.19063
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 -2.19063
GPHA2 glycoprotein hormone alpha 2 -2.19063
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -2.19063
BCL3 B-cell CLL/lymphoma 3 -2.19063
LRRC19 leucine rich repeat containing 19 -2.19063
UPK2 uroplakin 2 -2.19063
ZNF470 zinc finger protein 470 -2.19063
TOM1L2 target of myb1-like 2 (chicken) -2.19063
TMEM150C transmembrane protein 150C -2.19063
ACER2 alkaline ceramidase 2 -2.18704
KLK1 kallikrein 1 -2.18704
ZNF234 zinc finger protein 234 -2.15363
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.15152
SPTBN2 spectrin, beta, non-erythrocytic 2 -2.14324
INPP1 inositol polyphosphate-1-phosphatase -2.14324
BEND4 BEN domain containing 4 -2.13648
FOXN2 forkhead box N2 -2.12623
FOXP4 forkhead box P4 -2.07223
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -2.07114
GOLGA6L4 golgin A6 family-like 4 -2.06132
TMEM171 transmembrane protein 171 -2.06132
SLC25A34 solute carrier family 25, member 34 -2.06132
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 -2.06132
DIAPH2 diaphanous-related formin 2 -2.06132
DEUP1 deuterosome assembly protein 1 -2.06132
DUSP29 dual specificity phosphatase 29 -2.06132
CFAP100 cilia and flagella associated protein 100 -2.06132
KNL1 kinetochore scaffold 1 -2.06132
FYB1 FYN binding protein 1 -2.06132
GOLGA6L7 golgin A6 family like 7 -2.06132
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 -2.06132
TBC1D3L TBC1 domain family, member 3L -2.06132
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.06132
PON1 paraoxonase 1 -2.06132
AMIGO1 adhesion molecule with Ig-like domain 1 -2.06132
RGS11 regulator of G-protein signaling 11 -2.06132
BMX BMX non-receptor tyrosine kinase -2.06132
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.06132
ETV2 ets variant 2 -2.06132
APOB apolipoprotein B -2.06132
SNAI2 snail family zinc finger 2 -2.06132
HIGD1B HIG1 hypoxia inducible domain family, member 1B -2.06132
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.06132
ANKRD61 ankyrin repeat domain 61 -2.06132
ZNF843 zinc finger protein 843 -2.06132
DRD3 dopamine receptor D3 -2.06132
AMDHD1 amidohydrolase domain containing 1 -2.06132
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -2.06132
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -2.06132
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -2.06132
FZD9 frizzled class receptor 9 -2.06132
TARS3 threonyl-tRNA synthetase 3 -2.05247
ERCC5 excision repair cross-complementation group 5 -2.04534
CTNND2 catenin (cadherin-associated protein), delta 2 -2.04534
TMEM187 transmembrane protein 187 -2.03868
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -2.03845
SEZ6L seizure related 6 homolog (mouse)-like -2.03413
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.03413
TMX3 thioredoxin-related transmembrane protein 3 -2.03413
ASB16 ankyrin repeat and SOCS box containing 16 -2.03413
PGBD4 piggyBac transposable element derived 4 -2.03413