Waist Circumference Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description The measurement around the body at the level of the ABDOMEN and just above the hip bone. The measurement is usually taken immediately after exhalation. (Experimental Factor Ontology, EFO_0004342)
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Genes

146 genes associated with the trait Waist Circumference in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
FTO fat mass and obesity associated 1.35834
UMOD uromodulin 0.897125
BBX bobby sox homolog (Drosophila) 0.868031
LIN28B lin-28 homolog B (C. elegans) 0.722459
NRXN3 neurexin 3 0.685324
TPH2 tryptophan hydroxylase 2 0.572074
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.569421
RPL23P9 ribosomal protein L23 pseudogene 9 0.552366
SCHIP1 schwannomin interacting protein 1 0.518003
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.485885
CCDC169 coiled-coil domain containing 169 0.471054
ASPHD1 aspartate beta-hydroxylase domain containing 1 0.443956
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.443956
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.443956
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.443956
FAM177A1 family with sequence similarity 177, member A1 0.414812
SP140 SP140 nuclear body protein 0.403716
PTPRG protein tyrosine phosphatase, receptor type, G 0.393074
IL1RAP interleukin 1 receptor accessory protein 0.378873
KLHL36 kelch-like family member 36 0.378873
SOS2 son of sevenless homolog 2 (Drosophila) 0.363365
ACOT11 acyl-CoA thioesterase 11 0.362112
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.35113
KSR2 kinase suppressor of ras 2 0.345049
NEB nebulin 0.344875
ANO3 anoctamin 3 0.328305
CCND3 cyclin D3 0.324515
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.320395
SP110 SP110 nuclear body protein 0.316774
LY86-AS1 LY86 antisense RNA 1 0.315231
DPT dermatopontin 0.314379
ZFHX3 zinc finger homeobox 3 0.312355
C6ORF106 chromosome 6 open reading frame 106 0.305621
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.303694
KALRN kalirin, RhoGEF kinase 0.289245
PCAT4 prostate cancer associated transcript 4 (non-protein coding) 0.287938
DNAH10 dynein, axonemal, heavy chain 10 0.278777
TENM4 teneurin transmembrane protein 4 0.272191
KANK4 KN motif and ankyrin repeat domains 4 0.243139
UBASH3B ubiquitin associated and SH3 domain containing B 0.2387
COL4A1 collagen, type IV, alpha 1 0.236978
MED27 mediator complex subunit 27 0.236884
OR7G1 olfactory receptor, family 7, subfamily G, member 1 0.236695
SLC39A12 solute carrier family 39 (zinc transporter), member 12 0.234882
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.233068
FAM178A family with sequence similarity 178, member A 0.231649
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.23067
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.230374
GRIK4 glutamate receptor, ionotropic, kainate 4 0.227667
UHRF1BP1 UHRF1 binding protein 1 0.224545
PCDH7 protocadherin 7 0.212185
UBE2J2 ubiquitin-conjugating enzyme E2, J2 0.210222
EDDM3DP epididymal protein 3D, pseudogene 0.209352
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 0.205697
EPAS1 endothelial PAS domain protein 1 0.204816
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.203407
SRPK2 SRSF protein kinase 2 0.200578
ZFAT zinc finger and AT hook domain containing 0.198031
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.186296
LHFP lipoma HMGIC fusion partner 0.185427
KIF26A kinesin family member 26A 0.185361
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.184732
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.181402
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.180626
SMYD3 SET and MYND domain containing 3 0.177807
CHN2 chimerin 2 0.177381
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.168498
FANK1 fibronectin type III and ankyrin repeat domains 1 0.16837
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.168209
BCCIP BRCA2 and CDKN1A interacting protein 0.166776
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.166776
DLG2 discs, large homolog 2 (Drosophila) 0.159988
FHIT fragile histidine triad 0.159113
PACRG PARK2 co-regulated 0.155275
AMBP alpha-1-microglobulin/bikunin precursor 0.153839
LMO7 LIM domain 7 0.153239
RYR2 ryanodine receptor 2 (cardiac) 0.149969
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.149734
TKT transketolase 0.148019
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.146845
IRG1 immunoresponsive 1 homolog (mouse) 0.146448
RBM47 RNA binding motif protein 47 0.145883
EVA1A eva-1 homolog A (C. elegans) 0.145489
HDAC9 histone deacetylase 9 0.144707
AGBL1 ATP/GTP binding protein-like 1 0.139086
L2HGDH L-2-hydroxyglutarate dehydrogenase 0.131403
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 0.131403
PFKP phosphofructokinase, platelet 0.129369
FAM13A family with sequence similarity 13, member A 0.126181
RNF215 ring finger protein 215 0.124459
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.124459
KLF12 Kruppel-like factor 12 0.123499
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.121776
CDH13 cadherin 13 0.120611
PCP4 Purkinje cell protein 4 0.11512
RGS6 regulator of G-protein signaling 6 0.11241
CCDC88C coiled-coil domain containing 88C 0.108614
CSMD3 CUB and Sushi multiple domains 3 0.106945
TOB1 transducer of ERBB2, 1 0.104405
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.102995
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.101988
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.098662
IL6 interleukin 6 0.097217
CTSD cathepsin D 0.094796
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.092384
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.091735
CAMTA1 calmodulin binding transcription activator 1 0.091539
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.091045
SARDH sarcosine dehydrogenase 0.090673
STON1 stonin 1 0.088013
STON1-GTF2A1L STON1-GTF2A1L readthrough 0.088013
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.086078
TGIF1 TGFB-induced factor homeobox 1 0.085769
ECT2L epithelial cell transforming 2 like 0.085699
LPAR1 lysophosphatidic acid receptor 1 0.084133
NRG1 neuregulin 1 0.080492
HAS3 hyaluronan synthase 3 0.080203
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.079902
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.079551
NPAS3 neuronal PAS domain protein 3 0.078364
TLE4 transducin-like enhancer of split 4 0.077777
SAMD4A sterile alpha motif domain containing 4A 0.07727
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.076352
OPRM1 opioid receptor, mu 1 0.07505
IPCEF1 interaction protein for cytohesin exchange factors 1 0.07505
RBBP5 retinoblastoma binding protein 5 0.074157
SNX25 sorting nexin 25 0.071819
MYO18B myosin XVIIIB 0.071113
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.067834
KRI1 KRI1 homolog (S. cerevisiae) 0.067505
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.066412
FAM155A family with sequence similarity 155, member A 0.066349
TSPAN11 tetraspanin 11 0.064879
NUP85 nucleoporin 85kDa 0.064069
CDH23 cadherin-related 23 0.063243
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.063149
C10ORF105 chromosome 10 open reading frame 105 0.063055
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.060282
PAX7 paired box 7 0.060086
SUMO3 small ubiquitin-like modifier 3 0.05998
C11ORF24 chromosome 11 open reading frame 24 0.059501
MEIS2 Meis homeobox 2 0.059308
FAM69C family with sequence similarity 69, member C 0.059114
OR51I2 olfactory receptor, family 51, subfamily I, member 2 0.05897
SPIDR scaffolding protein involved in DNA repair 0.058914
KIAA1614 KIAA1614 0.05853