Waldenstrom Macroglobulinemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A malignant monoclonal gammopathy characterized by a high level of an IgM monoclonal protein. (Human Phenotype Ontology, HP_0005508)
External Link https://www.disgenet.org/browser/0/1/0/C0024419
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Genes

153 genes associated with the disease Waldenstrom Macroglobulinemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AICDA activation-induced cytidine deaminase
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANPEP alanyl (membrane) aminopeptidase
ANXA5 annexin A5
ARHGAP24 Rho GTPase activating protein 24
ARID1A AT rich interactive domain 1A (SWI-like)
AURKA aurora kinase A
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCL9 B-cell CLL/lymphoma 9
BCR breakpoint cluster region
BLM Bloom syndrome, RecQ helicase-like
BLNK B-cell linker
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSG basigin (Ok blood group)
BTK Bruton agammaglobulinemia tyrosine kinase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL3 chemokine (C-C motif) ligand 3
CCND1 cyclin D1
CCND3 cyclin D3
CD19 CD19 molecule
CD200 CD200 molecule
CD22 CD22 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD52 CD52 molecule
CD6 CD6 molecule
CD70 CD70 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CDKN2A cyclin-dependent kinase inhibitor 2A
CLEC12A C-type lectin domain family 12, member A
COLEC10 collectin sub-family member 10 (C-type lectin)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTRL chymotrypsin-like
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR4 chemokine (C-X-C motif) receptor 4
EFNB2 ephrin-B2
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EXOC2 exocyst complex component 2
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGFR3 fibroblast growth factor receptor 3
GLI2 GLI family zinc finger 2
GRAP2 GRB2-related adaptor protein 2
HAS1 hyaluronan synthase 1
HAS2 hyaluronan synthase 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC9 histone deacetylase 9
HMMR hyaluronan-mediated motility receptor (RHAMM)
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IGH immunoglobulin heavy locus
IL10 interleukin 10
IL1B interleukin 1, beta
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK4 interleukin-1 receptor-associated kinase 4
IRF4 interferon regulatory factor 4
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT20 keratin 20, type I
LAPTM5 lysosomal protein transmembrane 5
LEF1 lymphoid enhancer-binding factor 1
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LPL lipoprotein lipase
MALT1 MALT1 paracaspase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MCL1 myeloid cell leukemia 1
MMP8 matrix metallopeptidase 8
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYOM2 myomesin 2
NAMPT nicotinamide phosphoribosyltransferase
NCAM1 neural cell adhesion molecule 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOTCH2 notch 2
PAX5 paired box 5
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POU2AF1 POU class 2 associating factor 1
POU2F1 POU class 2 homeobox 1
POU2F2 POU class 2 homeobox 2
PRIMA1 proline rich membrane anchor 1
PRKCD protein kinase C, delta
PTPRC protein tyrosine phosphatase, receptor type, C
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SDC1 syndecan 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOAT1 sterol O-acyltransferase 1
SPI1 Spi-1 proto-oncogene
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STOML2 stomatin (EPB72)-like 2
SYK spleen tyrosine kinase
TCL1A T-cell leukemia/lymphoma 1A
TCL1B T-cell leukemia/lymphoma 1B
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TP73 tumor protein p73
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
XBP1 X-box binding protein 1
XPO1 exportin 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZHX2 zinc fingers and homeoboxes 2