West Nile Fever Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in infection, has_material_basis_in West Nile virus, which is transmitted_by Culex and transmitted_by Aedes mosquitoes. The infection has_symptom fever, has_symptom sore throat, has_symptom headache, has_symptom body ache, has_symptom nausea, has_symptom maculopapular rash and has_symptom vomiting. (Human Disease Ontology, DOID_2366)
External Link https://www.disgenet.org/browser/0/1/0/C0751584
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Genes

173 genes associated with the disease West Nile Fever in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACTB actin, beta
AGFG1 ArfGAP with FG repeats 1
AIF1 allograft inflammatory factor 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATG5 autophagy related 5
AXL AXL receptor tyrosine kinase
BCAP31 B-cell receptor-associated protein 31
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BRD2 bromodomain containing 2
CAPRIN1 cell cycle associated protein 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD180 CD180 molecule
CD40LG CD40 ligand
CD48 CD48 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CPVL carboxypeptidase, vitellogenic-like
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DCAF1 DDB1 and CUL4 associated factor 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DNALI1 dynein, axonemal, light intermediate chain 1
DOCK11 dedicator of cytokinesis 11
ELF4 E74-like factor 4 (ets domain transcription factor)
ERVW-1 endogenous retrovirus group W, member 1
FAM134B family with sequence similarity 134, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXP3 forkhead box P3
FRMD7 FERM domain containing 7
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GBA glucosidase, beta, acid
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GEM GTP binding protein overexpressed in skeletal muscle
GLS glutaminase
GOSR1 golgi SNAP receptor complex member 1
GSTO1 glutathione S-transferase omega 1
HAVCR2 hepatitis A virus cellular receptor 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HPR haptoglobin-related protein
IFIH1 interferon induced with helicase C domain 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM3 interferon induced transmembrane protein 3
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA2 interferon, alpha 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL27 interleukin 27
IRF3 interferon regulatory factor 3
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
IVNS1ABP influenza virus NS1A binding protein
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMC2 laminin, gamma 2
LAMP3 lysosomal-associated membrane protein 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSAMP limbic system-associated membrane protein
LY6E lymphocyte antigen 6 complex, locus E
LZTR1 leucine-zipper-like transcription regulator 1
MAVS mitochondrial antiviral signaling protein
MBL2 mannose-binding lectin (protein C) 2, soluble
MICB MHC class I polypeptide-related sequence B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP9 matrix metallopeptidase 9
MX1 MX dynamin-like GTPase 1
NAMPT nicotinamide phosphoribosyltransferase
NLRP3 NLR family, pyrin domain containing 3
NR4A3 nuclear receptor subfamily 4, group A, member 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAH phenylalanine hydroxylase
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIWIL1 piwi-like RNA-mediated gene silencing 1
PIWIL4 piwi-like RNA-mediated gene silencing 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLB1 phospholipase B1
PLCE1 phospholipase C, epsilon 1
PNKP polynucleotide kinase 3'-phosphatase
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTX3 pentraxin 3, long
PYM1 PYM homolog 1, exon junction complex associated factor
PZP pregnancy-zone protein
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RB1 retinoblastoma 1
RBM45 RNA binding motif protein 45
RBM8A RNA binding motif protein 8A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPAIN RPA interacting protein
RSAD2 radical S-adenosyl methionine domain containing 2
SARS1 seryl-tRNA synthetase 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCT secretin
SDS serine dehydratase
SEC14L2 SEC14-like 2 (S. cerevisiae)
SELENBP1 selenium binding protein 1
SETX senataxin
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A4 solute carrier family 16, member 4
SLFN11 schlafen family member 11
SMAD4 SMAD family member 4
SMOC1 SPARC related modular calcium binding 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS3 suppressor of cytokine signaling 3
SPP1 secreted phosphoprotein 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYP synaptophysin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TLR3 toll-like receptor 3
TMED5 transmembrane emp24 protein transport domain containing 5
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRAIP TRAF interacting protein
TRIM6 tripartite motif containing 6
TTC4 tetratricopeptide repeat domain 4
VAMP8 vesicle-associated membrane protein 8
VCP valosin containing protein
VHLL von Hippel-Lindau tumor suppressor-like
XBP1 X-box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBP1 Z-DNA binding protein 1
ZMYND10 zinc finger, MYND-type containing 10