XIMELAGATRAN Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted to the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage. (Chemical Entities of Biological Interest Ontology, CHEBI_65172)
External Link https://dgidb.org/results?searchType=drug&searchTerms=XIMELAGATRAN
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Genes

1 interacting proteins for the XIMELAGATRAN drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
F2 coagulation factor II (thrombin) 4.50485