XL765 Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A sulfonamide obtained by formal condensation of the sulfonic acid group of 4-[(3-methoxy-4-methylbenzoyl)amino]benzenesulfonic acid with the primary aromatic amino group of N-(3,5-dimethoxyphenyl)quinoxaline-2,3-diamine. A dual PI3K/mTOR inhibitor used in cancer treatment. (Chemical Entities of Biological Interest Ontology, CHEBI_71958)
External Link https://dgidb.org/results?searchType=drug&searchTerms=XL765
Similar Terms
Downloads & Tools

Genes

4 interacting proteins for the XL765 drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.149525
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.106718
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.093851
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.0711451