XMD8-92 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
Description A dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a [2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino substituent. It is an inhibitor of the BMK1 kinase pathway. (Chemical Entities of Biological Interest Ontology, CHEBI_60325)
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3 kinases inhibited by the XMD8-92 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
DCLK2 doublecortin-like kinase 2 1.3104
DCLK1 doublecortin-like kinase 1 1.29393
TNK1 tyrosine kinase, non-receptor, 1 0.915387