XPA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description xeroderma pigmentosum, complementation group A|This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 7507)
External Link http://www.ncbi.nlm.nih.gov/gene/7507
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Genes

170 interacting proteins for XPA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ALYREF Aly/REF export factor
ASF1A anti-silencing function 1A histone chaperone
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BANF1 barrier to autointegration factor 1
C19ORF53 chromosome 19 open reading frame 53
CAPRIN1 cell cycle associated protein 1
CCDC59 coiled-coil domain containing 59
CCDC86 coiled-coil domain containing 86
CD3EAP CD3e molecule, epsilon associated protein
CENPV centromere protein V
CGGBP1 CGG triplet repeat binding protein 1
CIRBP cold inducible RNA binding protein
CNBP CCHC-type zinc finger, nucleic acid binding protein
DAZAP1 DAZ associated protein 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EIF4H eukaryotic translation initiation factor 4H
EP300 E1A binding protein p300
ERCC1 excision repair cross-complementation group 1
ERCC6 excision repair cross-complementation group 6
FBL fibrillarin
FOSL1 FOS-like antigen 1
FUS FUS RNA binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GPN1 GPN-loop GTPase 1
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H4F histone cluster 1, H4f
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPA8 heat shock 70kDa protein 8
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KIFC1 kinesin family member C1
LIG3 ligase III, DNA, ATP-dependent
LIN28B lin-28 homolog B (C. elegans)
LYZ lysozyme
MARK2 MAP/microtubule affinity-regulating kinase 2
METTL17 methyltransferase like 17
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MRPS23 mitochondrial ribosomal protein S23
MSH2 mutS homolog 2
MSH3 mutS homolog 3
NRF1 nuclear respiratory factor 1
NUCLEOLIN nucleolin multifunctional protein
NUSAP1 nucleolar and spindle associated protein 1
NXF1 nuclear RNA export factor 1
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PCBP1 poly(rC) binding protein 1
PEG10 paternally expressed 10
PNKP polynucleotide kinase 3'-phosphatase
POLG polymerase (DNA directed), gamma
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTBP1 polypyrimidine tract binding protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM14 RNA binding motif protein 14
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBM39 RNA binding motif protein 39
RBM4 RNA binding motif protein 4
RBMX RNA binding motif protein, X-linked
RECQL RecQ helicase-like
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNMT RNA (guanine-7-) methyltransferase
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RPA4 replication protein A4, 30kDa
RPL17 ribosomal protein L17
RPL19 ribosomal protein L19
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL26L1 ribosomal protein L26-like 1
RPL27A ribosomal protein L27a
RPL31 ribosomal protein L31
RPL35 ribosomal protein L35
RPL36A ribosomal protein L36a
RPL37 ribosomal protein L37
RPL38 ribosomal protein L38
RPL8 ribosomal protein L8
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS2 ribosomal protein S2
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS27A ribosomal protein S27a
RPS28 ribosomal protein S28
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
SATB1 SATB homeobox 1
SIRT1 sirtuin 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF4 serine/arginine-rich splicing factor 4
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SUB1 SUB1 homolog (S. cerevisiae)
SYNE1 spectrin repeat containing, nuclear envelope 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TFAM transcription factor A, mitochondrial
THRAP3 thyroid hormone receptor associated protein 3
THYN1 thymocyte nuclear protein 1
TOP1 topoisomerase (DNA) I
UHRF1 ubiquitin-like with PHD and ring finger domains 1
USP10 ubiquitin specific peptidase 10
XAB2 XPA binding protein 2
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP91 ZFP91 zinc finger protein
ZNF787 zinc finger protein 787