| Dataset | ENCODE Transcription Factor Targets |
| Category | genomics |
| Type | transcription factor |
| Description | X-ray repair complementing defective repair in Chinese hamster cells 4|The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008] (NCBI Entrez Gene Database, 7518) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/7518 |
| Similar Terms | |
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4 target genes of the XRCC4 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
