XRCC6 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description X-ray repair complementing defective repair in Chinese hamster cells 6|The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2547)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_G22P1
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Genes

192 co-expressed genes for XRCC6 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACLY ATP citrate lyase
ACP1 acid phosphatase 1, soluble
ANAPC5 anaphase promoting complex subunit 5
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
BAG6 BCL2-associated athanogene 6
BTF3 basic transcription factor 3
BUB3 BUB3 mitotic checkpoint protein
C14ORF166 chromosome 14 open reading frame 166
CBX3 chromobox homolog 3
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC123 cell division cycle 123
CDC37 cell division cycle 37
CDV3 CDV3 homolog (mouse)
CHD4 chromodomain helicase DNA binding protein 4
CLIC1 chloride intracellular channel 1
CLNS1A chloride channel, nucleotide-sensitive, 1A
COMMD4 COMM domain containing 4
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5B cytochrome c oxidase subunit Vb
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
COX7C cytochrome c oxidase subunit VIIc
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CSNK2B casein kinase 2, beta polypeptide
CTBP1 C-terminal binding protein 1
CTDNEP1 CTD nuclear envelope phosphatase 1
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DEK DEK proto-oncogene
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DRG1 developmentally regulated GTP binding protein 1
DYNLL1 dynein, light chain, LC8-type 1
EID1 EP300 interacting inhibitor of differentiation 1
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF4H eukaryotic translation initiation factor 4H
ERH enhancer of rudimentary homolog (Drosophila)
EXOSC8 exosome component 8
FAM168B family with sequence similarity 168, member B
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FBL fibrillarin
FUS FUS RNA binding protein
GANAB glucosidase, alpha; neutral AB
GDI2 GDP dissociation inhibitor 2
GPN1 GPN-loop GTPase 1
H2AFV H2A histone family, member V
H2AFZ H2A histone family, member Z
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HDAC1 histone deacetylase 1
HDGF hepatoma-derived growth factor
HMGN1 high mobility group nucleosome binding domain 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPB11 heat shock protein family B (small), member 11
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
ILF2 interleukin enhancer binding factor 2
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
JTB jumping translocation breakpoint
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAEA macrophage erythroblast attacher
MCM7 minichromosome maintenance complex component 7
MDH1 malate dehydrogenase 1, NAD (soluble)
MRPL23 mitochondrial ribosomal protein L23
MRPL9 mitochondrial ribosomal protein L9
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
NACA nascent polypeptide-associated complex alpha subunit
NAP1L1 nucleosome assembly protein 1-like 1
NARS asparaginyl-tRNA synthetase
NCL nucleolin
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NONO non-POU domain containing, octamer-binding
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP62 nucleoporin 62kDa
PABPN1 poly(A) binding protein, nuclear 1
PARK7 parkinson protein 7
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCNA proliferating cell nuclear antigen
PDIA6 protein disulfide isomerase family A, member 6
PES1 pescadillo ribosomal biogenesis factor 1
PGK1 phosphoglycerate kinase 1
PHB2 prohibitin 2
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRMT1 protein arginine methyltransferase 1
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PTBP1 polypyrimidine tract binding protein 1
PUF60 poly-U binding splicing factor 60KDa
QARS glutaminyl-tRNA synthetase
RAD23A RAD23 homolog A (S. cerevisiae)
RAN RAN, member RAS oncogene family
RBM14 RNA binding motif protein 14
RBM4 RNA binding motif protein 4
RBMX RNA binding motif protein, X-linked
RNPS1 RNA binding protein S1, serine-rich domain
RPL14 ribosomal protein L14
RPL24 ribosomal protein L24
RPL26L1 ribosomal protein L26-like 1
SAMM50 SAMM50 sorting and assembly machinery component
SAP18 Sin3A-associated protein, 18kDa
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SET SET nuclear proto-oncogene
SF3A1 splicing factor 3a, subunit 1, 120kDa
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMC1A structural maintenance of chromosomes 1A
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNRPC small nuclear ribonucleoprotein polypeptide C
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNX3 sorting nexin 3
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF9 serine/arginine-rich splicing factor 9
STARD7 StAR-related lipid transfer (START) domain containing 7
STRAP serine/threonine kinase receptor associated protein
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TARDBP TAR DNA binding protein
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCP1 t-complex 1
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TRA2B transformer 2 beta homolog (Drosophila)
TRIM28 tripartite motif containing 28
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TTC1 tetratricopeptide repeat domain 1
TUFM Tu translation elongation factor, mitochondrial
TXNL4A thioredoxin-like 4A
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2I ubiquitin-conjugating enzyme E2I
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UQCRH ubiquinol-cytochrome c reductase hinge protein
USP22 ubiquitin specific peptidase 22
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC2 voltage-dependent anion channel 2
WBP11 WW domain binding protein 11
WDR1 WD repeat domain 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZNF207 zinc finger protein 207