| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the XRK3F2_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.114981 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.113606 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0959891 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0831871 |
| LPIN1 | lipin 1 | 0.0753766 |
| B2M | beta-2-microglobulin | 0.0623488 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0621776 |
| VIM | vimentin | 0.0590846 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0582849 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0565673 |
| ENAH | enabled homolog (Drosophila) | 0.0563437 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0543651 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0541407 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0489333 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0486658 |
| RPS6 | ribosomal protein S6 | 0.0480862 |
| JMJD1C | jumonji domain containing 1C | 0.0477773 |
| RPS21 | ribosomal protein S21 | 0.0476523 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0475703 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.046236 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0462119 |
| RPL19 | ribosomal protein L19 | 0.0451056 |
| HIP1 | huntingtin interacting protein 1 | 0.0442503 |
| RPS12 | ribosomal protein S12 | 0.0440584 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0428045 |
| AHNAK | AHNAK nucleoprotein | 0.0426608 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0422553 |
| FTL | ferritin, light polypeptide | 0.0419702 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0419083 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0412442 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0404009 |
| CALD1 | caldesmon 1 | 0.0399413 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0391365 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0386113 |
| TNPO1 | transportin 1 | 0.0384954 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0382409 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0367826 |
| MAP1B | microtubule-associated protein 1B | 0.0346746 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0341964 |
| EXOC6B | exocyst complex component 6B | 0.0340545 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0335117 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.032808 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0326635 |
| MSI2 | musashi RNA-binding protein 2 | 0.0322059 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0320492 |
| RPS15 | ribosomal protein S15 | 0.0316672 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0313768 |
| THBS1 | thrombospondin 1 | 0.031321 |
| ITGAV | integrin, alpha V | 0.0309191 |
| H3-3B | H3.3 histone B | 0.0308751 |
| RPL31 | ribosomal protein L31 | 0.0306899 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0298111 |
| DGKH | diacylglycerol kinase, eta | 0.0291889 |
| RPS3 | ribosomal protein S3 | 0.0290166 |
| RPLP1 | ribosomal protein, large, P1 | 0.0287149 |
| RPL38 | ribosomal protein L38 | 0.028664 |
| RPS10 | ribosomal protein S10 | 0.0285174 |
| RPL32 | ribosomal protein L32 | 0.0283275 |
| RPS27A | ribosomal protein S27a | 0.0278302 |
| LSAMP | limbic system-associated membrane protein | 0.0273192 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.027301 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0271689 |
| TPR | translocated promoter region, nuclear basket protein | 0.0269497 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.026731 |
| EGFR | epidermal growth factor receptor | 0.026379 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0262895 |
| PGK1 | phosphoglycerate kinase 1 | 0.0262573 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0262467 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0262225 |
| RPL35A | ribosomal protein L35a | 0.0260136 |
| OTUD7B | OTU deubiquitinase 7B | 0.0258715 |
| SQSTM1 | sequestosome 1 | 0.0258286 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0257397 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0257134 |
| RPLP0 | ribosomal protein, large, P0 | 0.0257015 |
| MEGF9 | multiple EGF-like-domains 9 | 0.0256697 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0256557 |
| KYNU | kynureninase | 0.0255164 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0254207 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0253164 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0252061 |
| KIF26B | kinesin family member 26B | 0.0249275 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0248987 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0248583 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0247923 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0247739 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0247102 |
| UBC | ubiquitin C | 0.0246476 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0246062 |
| RPL4 | ribosomal protein L4 | 0.0243792 |
| SERINC3 | serine incorporator 3 | 0.0243704 |
| USP53 | ubiquitin specific peptidase 53 | 0.0242895 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0241977 |
| ZNF148 | zinc finger protein 148 | 0.0238133 |
| CDK19 | cyclin-dependent kinase 19 | 0.023794 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0237717 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0234245 |
| RUNX1 | runt-related transcription factor 1 | 0.0234124 |
| MYO1D | myosin ID | 0.0233162 |
| NEK7 | NIMA-related kinase 7 | 0.0233055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.192975 |
| IGF2 | insulin-like growth factor 2 | -0.190493 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.115161 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.105235 |
| PRKCA | protein kinase C, alpha | -0.0864361 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0761332 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0683904 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0663135 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0659706 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.059813 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.059515 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.058254 |
| NF1 | neurofibromin 1 | -0.0582067 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0547443 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0515874 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0497747 |
| HMGA2 | high mobility group AT-hook 2 | -0.0491098 |
| COL3A1 | collagen, type III, alpha 1 | -0.0446597 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0444347 |
| PDE10A | phosphodiesterase 10A | -0.0434024 |
| EGR1 | early growth response 1 | -0.0412828 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0406219 |
| MYO6 | myosin VI | -0.0402151 |
| FAM107B | family with sequence similarity 107, member B | -0.0395915 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0393068 |
| TENM4 | teneurin transmembrane protein 4 | -0.0390263 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0389545 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0383578 |
| SMYD3 | SET and MYND domain containing 3 | -0.0377042 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0374491 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0369534 |
| ASPH | aspartate beta-hydroxylase | -0.0369291 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0362574 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0358242 |
| MEF2A | myocyte enhancer factor 2A | -0.0358107 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0356205 |
| DNM3 | dynamin 3 | -0.0355627 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0351562 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.034838 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0340533 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0338886 |
| ZNF638 | zinc finger protein 638 | -0.0331316 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0331192 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0325721 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0323674 |
| DTNA | dystrobrevin, alpha | -0.0323483 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0323172 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0322502 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0319885 |
| ATRNL1 | attractin-like 1 | -0.0316581 |
| LRRC7 | leucine rich repeat containing 7 | -0.0315469 |
| KIAA1217 | KIAA1217 | -0.0314779 |
| MCL1 | myeloid cell leukemia 1 | -0.0309189 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0307464 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0306009 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0305881 |
| FAM13A | family with sequence similarity 13, member A | -0.0303279 |
| GPC6 | glypican 6 | -0.0302001 |
| PRKCE | protein kinase C, epsilon | -0.0300641 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0297799 |
| NDRG1 | N-myc downstream regulated 1 | -0.029306 |
| RGS4 | regulator of G-protein signaling 4 | -0.0292168 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0291749 |
| PLPP1 | phospholipid phosphatase 1 | -0.0289267 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0288538 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.02875 |
| SCFD1 | sec1 family domain containing 1 | -0.0287228 |
| RAD51B | RAD51 paralog B | -0.0285664 |
| DPH6 | diphthamine biosynthesis 6 | -0.028518 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0284082 |
| CADM1 | cell adhesion molecule 1 | -0.0283302 |
| PTGES2 | prostaglandin E synthase 2 | -0.0281886 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0274535 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0273592 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0272268 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0272079 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0266362 |
| NREP | neuronal regeneration related protein | -0.0265673 |
| CDH13 | cadherin 13 | -0.0263087 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0262795 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0260807 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.025962 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0254409 |
| TCF12 | transcription factor 12 | -0.0252821 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0250765 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0246944 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0246671 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0245533 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0245418 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0244191 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0244136 |
| GOLGB1 | golgin B1 | -0.0240696 |
| AEBP2 | AE binding protein 2 | -0.0239667 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0239576 |
| VMP1 | vacuole membrane protein 1 | -0.0238965 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0236615 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0235099 |
| STC1 | stanniocalcin 1 | -0.0234915 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0234083 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0232422 |
