| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | 0.0753186 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0538783 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0481979 |
| MYOF | myoferlin | 0.0396839 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0387322 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0368796 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0361435 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0358204 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0337492 |
| AOPEP | aminopeptidase O (putative) | 0.0305179 |
| ITGB8 | integrin, beta 8 | 0.0287403 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0282238 |
| KLHL24 | kelch-like family member 24 | 0.0262938 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0255931 |
| HLA-E | major histocompatibility complex, class I, E | 0.0254971 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0254184 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.024083 |
| OPTN | optineurin | 0.023763 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0236118 |
| CLDN1 | claudin 1 | 0.0235347 |
| GBP4 | guanylate binding protein 4 | 0.0232409 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0232018 |
| PLAT | plasminogen activator, tissue | 0.0231575 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0226028 |
| TXNRD1 | thioredoxin reductase 1 | 0.0225488 |
| CD44 | CD44 molecule (Indian blood group) | 0.0224522 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0224242 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0219309 |
| TXNIP | thioredoxin interacting protein | 0.0219147 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0212974 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.0210265 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0204942 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0200248 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0194584 |
| B2M | beta-2-microglobulin | 0.0193256 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0189088 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.018649 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0182931 |
| TKT | transketolase | 0.0178042 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0177404 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0176408 |
| SQSTM1 | sequestosome 1 | 0.0173398 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.017126 |
| ATP9A | ATPase, class II, type 9A | 0.0168531 |
| PLPP1 | phospholipid phosphatase 1 | 0.0167383 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0164776 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0161208 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0161027 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0159249 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0156881 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0155111 |
| PLAC8 | placenta-specific 8 | 0.0155061 |
| GUCY1A1 | guanylate cyclase 1 soluble subunit alpha 1 | 0.0153983 |
| MX2 | MX dynamin-like GTPase 2 | 0.0153972 |
| MT1E | metallothionein 1E | 0.0152622 |
| YBX3 | Y box binding protein 3 | 0.0152195 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.014923 |
| MX1 | MX dynamin-like GTPase 1 | 0.0149127 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0148463 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.014696 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0146886 |
| DENND4C | DENN/MADD domain containing 4C | 0.0145964 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.014499 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0144645 |
| TJP2 | tight junction protein 2 | 0.0142569 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0141963 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0141768 |
| KYNU | kynureninase | 0.0141012 |
| IFI44L | interferon-induced protein 44-like | 0.0138458 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0137806 |
| NTN4 | netrin 4 | 0.0135774 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.0135425 |
| TJP1 | tight junction protein 1 | 0.0134396 |
| GLYAT | glycine-N-acyltransferase | 0.013423 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0133959 |
| TMOD1 | tropomodulin 1 | 0.0133579 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0133375 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0133137 |
| IL6ST | interleukin 6 signal transducer | 0.0131695 |
| KIF16B | kinesin family member 16B | 0.0131431 |
| HLA-B | major histocompatibility complex, class I, B | 0.0131103 |
| FOXO1 | forkhead box O1 | 0.0130452 |
| DOK5 | docking protein 5 | 0.0130032 |
| RNF213 | ring finger protein 213 | 0.0129902 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0128376 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0128371 |
| AUTS2 | autism susceptibility candidate 2 | 0.0128061 |
| PLPP6 | phospholipid phosphatase 6 | 0.0127659 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0126719 |
| CTSA | cathepsin A | 0.0126184 |
| SAMHD1 | SAM domain and HD domain 1 | 0.0124888 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0124759 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0124454 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.012434 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.0122737 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0120979 |
| PCM1 | pericentriolar material 1 | 0.0120698 |
| UBC | ubiquitin C | 0.0120661 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0119779 |
| APOL1 | apolipoprotein L, 1 | 0.0118611 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.249879 |
| FLNB | filamin B, beta | -0.202779 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.132718 |
| SLC35F3 | solute carrier family 35, member F3 | -0.124464 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0993923 |
| STC1 | stanniocalcin 1 | -0.0872119 |
| MTSS1 | metastasis suppressor 1 | -0.0852428 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0830939 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0798293 |
| INTS6 | integrator complex subunit 6 | -0.0702641 |
| HMGA2 | high mobility group AT-hook 2 | -0.0634122 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0623316 |
| ITGA6 | integrin, alpha 6 | -0.0615966 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0598592 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0587155 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0574118 |
| RASAL2 | RAS protein activator like 2 | -0.0558598 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0552212 |
| NDRG1 | N-myc downstream regulated 1 | -0.0551044 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0547285 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0542185 |
| LAMC2 | laminin, gamma 2 | -0.0538441 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.052808 |
| ASPH | aspartate beta-hydroxylase | -0.0526657 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0525703 |
| CDK6 | cyclin-dependent kinase 6 | -0.0515103 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0506424 |
| TMSB10 | thymosin beta 10 | -0.0495733 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0488465 |
| PODXL | podocalyxin-like | -0.0487932 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0485865 |
| RCOR1 | REST corepressor 1 | -0.0470881 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0468423 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0456818 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0454712 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.045356 |
| HM13 | histocompatibility (minor) 13 | -0.0448313 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0437475 |
| MYO10 | myosin X | -0.0429498 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0410734 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0386221 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0377214 |
| PALLD | palladin, cytoskeletal associated protein | -0.0372997 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0364493 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0362741 |
| PLEC | plectin | -0.0348254 |
| EMP1 | epithelial membrane protein 1 | -0.0341589 |
| ANXA2 | annexin A2 | -0.0334122 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.031847 |
| EGR1 | early growth response 1 | -0.0317855 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0316794 |
| PLS3 | plastin 3 | -0.0316209 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0315438 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0314425 |
| VCL | vinculin | -0.0309647 |
| RNF217 | ring finger protein 217 | -0.0307608 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0307072 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0306972 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0300504 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0299138 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0296628 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0296066 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0295755 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.029072 |
| PTK2 | protein tyrosine kinase 2 | -0.02872 |
| POTEF | POTE ankyrin domain family, member F | -0.0285264 |
| SULF2 | sulfatase 2 | -0.0284986 |
| AMOTL1 | angiomotin like 1 | -0.0282467 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0281477 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0276643 |
| PRSS23 | protease, serine, 23 | -0.0274466 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0274094 |
| S100A10 | S100 calcium binding protein A10 | -0.0271622 |
| BLCAP | bladder cancer associated protein | -0.0269903 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0266457 |
| SMYD3 | SET and MYND domain containing 3 | -0.0266452 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0266068 |
| DUSP6 | dual specificity phosphatase 6 | -0.0265724 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0264626 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0261122 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0254959 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0253432 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.025312 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0252365 |
| NAV2 | neuron navigator 2 | -0.0249954 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0249745 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.024586 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.024459 |
| RBM39 | RNA binding motif protein 39 | -0.0242932 |
| CD59 | CD59 molecule, complement regulatory protein | -0.024281 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0242326 |
| SERTAD2 | SERTA domain containing 2 | -0.0240394 |
| PTMA | prothymosin, alpha | -0.0240225 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0239942 |
| ACTN4 | actinin, alpha 4 | -0.0239828 |
| LUZP1 | leucine zipper protein 1 | -0.023843 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0237769 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0237431 |
| PYGL | phosphorylase, glycogen, liver | -0.023464 |
| CAPRIN2 | caprin family member 2 | -0.0233172 |
