| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.284276 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.14224 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.114311 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.111528 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.100681 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0969572 |
| MYO1E | myosin IE | 0.0918386 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0916556 |
| NPSR1 | neuropeptide S receptor 1 | 0.085137 |
| FOXP1 | forkhead box P1 | 0.0807312 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0804083 |
| FHIT | fragile histidine triad | 0.0794116 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0773377 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0755057 |
| RPS6 | ribosomal protein S6 | 0.0752891 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0699402 |
| POF1B | premature ovarian failure, 1B | 0.0697618 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0682022 |
| RAD51B | RAD51 paralog B | 0.0679852 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0654257 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0648847 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0632472 |
| NEBL | nebulette | 0.0598323 |
| RPS8 | ribosomal protein S8 | 0.0588778 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0585842 |
| RPL31 | ribosomal protein L31 | 0.0583483 |
| RPLP0 | ribosomal protein, large, P0 | 0.0537798 |
| MECOM | MDS1 and EVI1 complex locus | 0.0531639 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0527618 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0507856 |
| FTL | ferritin, light polypeptide | 0.0505486 |
| RPL9 | ribosomal protein L9 | 0.0492372 |
| MUC13 | mucin 13, cell surface associated | 0.0482825 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0481232 |
| FOXP2 | forkhead box P2 | 0.0467366 |
| PCDH9 | protocadherin 9 | 0.04569 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0439785 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0438228 |
| B2M | beta-2-microglobulin | 0.0435816 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0424479 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0409538 |
| NRXN3 | neurexin 3 | 0.0406514 |
| RPL35A | ribosomal protein L35a | 0.0405772 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0390756 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0389048 |
| RPS25 | ribosomal protein S25 | 0.0385547 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0383795 |
| RPS23 | ribosomal protein S23 | 0.038172 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0379473 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0376387 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0375047 |
| EXOC4 | exocyst complex component 4 | 0.0372199 |
| RPS13 | ribosomal protein S13 | 0.0362494 |
| VCL | vinculin | 0.0358687 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.0356359 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0352772 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0348092 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0345994 |
| CUX1 | cut-like homeobox 1 | 0.0340237 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0335865 |
| AREG | amphiregulin | 0.0333987 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0333519 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0332989 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0324539 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0324218 |
| ACTG1 | actin gamma 1 | 0.0324094 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0321577 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0318255 |
| AEBP2 | AE binding protein 2 | 0.0310619 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0307248 |
| RPL37A | ribosomal protein L37a | 0.0305273 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.030476 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0301622 |
| TSPAN8 | tetraspanin 8 | 0.0298861 |
| RPS29 | ribosomal protein S29 | 0.0296503 |
| RPL7 | ribosomal protein L7 | 0.0294002 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0293359 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0293105 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0292674 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0289074 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0288475 |
| RPL11 | ribosomal protein L11 | 0.0285178 |
| CD44 | CD44 molecule (Indian blood group) | 0.02808 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0280719 |
| DUSP16 | dual specificity phosphatase 16 | 0.0279675 |
| RPS27A | ribosomal protein S27a | 0.0278714 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.027729 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0274162 |
| WWOX | WW domain containing oxidoreductase | 0.0273006 |
| HNF4G | hepatocyte nuclear factor 4, gamma | 0.0271367 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0267398 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0265804 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0262752 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0262715 |
| MACROD2 | MACRO domain containing 2 | 0.0260741 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0258728 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0256583 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0255446 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0255026 |
| RPS20 | ribosomal protein S20 | 0.0253622 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139524 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103869 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0999546 |
| ASPH | aspartate beta-hydroxylase | -0.0972403 |
| ANXA2 | annexin A2 | -0.0953633 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0940607 |
| PTMA | prothymosin, alpha | -0.0931431 |
| TNS4 | tensin 4 | -0.0915778 |
| FLNB | filamin B, beta | -0.0781744 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0653008 |
| GOLGA4 | golgin A4 | -0.061853 |
| H1-0 | H1.0 linker histone | -0.0617242 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0615898 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0606905 |
| FAT1 | FAT atypical cadherin 1 | -0.0580217 |
| NDRG1 | N-myc downstream regulated 1 | -0.0577704 |
| TMSB10 | thymosin beta 10 | -0.0572233 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0546502 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.05072 |
| EZR | ezrin | -0.0494176 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0489788 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.046121 |
| EREG | epiregulin | -0.0455265 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.045294 |
| RNF43 | ring finger protein 43 | -0.045291 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0445346 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0442913 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.042498 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.04139 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0413648 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0412865 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0409133 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0406512 |
| RNF145 | ring finger protein 145 | -0.0404859 |
| TPM4 | tropomyosin 4 | -0.0404229 |
| KIF5B | kinesin family member 5B | -0.040343 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0402773 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0402392 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0399033 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0395391 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0394607 |
| RBM39 | RNA binding motif protein 39 | -0.0389132 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0387277 |
| FERMT1 | fermitin family member 1 | -0.0384142 |
| MED13L | mediator complex subunit 13-like | -0.0379054 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0373089 |
| TXNIP | thioredoxin interacting protein | -0.0372813 |
| OGA | O-GlcNAcase | -0.0359147 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0358662 |
| RREB1 | ras responsive element binding protein 1 | -0.0358445 |
| KRT8 | keratin 8, type II | -0.0354749 |
| KRT18 | keratin 18, type I | -0.0352646 |
| TOP1 | topoisomerase (DNA) I | -0.0347271 |
| FAM13A | family with sequence similarity 13, member A | -0.033802 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0336939 |
| RRBP1 | ribosome binding protein 1 | -0.03345 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0327693 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0320843 |
| RPS2 | ribosomal protein S2 | -0.0319911 |
| WDR45B | WD repeat domain 45B | -0.0315682 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0312609 |
| CLTC | clathrin, heavy chain (Hc) | -0.0306991 |
| CADPS | Ca++-dependent secretion activator | -0.0305346 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0304509 |
| S100A6 | S100 calcium binding protein A6 | -0.0304244 |
| TPM3 | tropomyosin 3 | -0.0302396 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.030113 |
| ITGB4 | integrin, beta 4 | -0.0299276 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0290515 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0287222 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0282424 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0279881 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0279827 |
| PRSS3 | protease, serine, 3 | -0.0279691 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.027916 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0278808 |
| S100P | S100 calcium binding protein P | -0.0277096 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0274765 |
| SETD5 | SET domain containing 5 | -0.0274487 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0271154 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0270567 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0270114 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0266548 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0264439 |
| FOSL1 | FOS-like antigen 1 | -0.0262981 |
| CCNY | cyclin Y | -0.0261317 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0260371 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0259715 |
| ACTN4 | actinin, alpha 4 | -0.0258813 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0257613 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0257193 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0256843 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0255405 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0254092 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0253723 |
| ZNF292 | zinc finger protein 292 | -0.0253563 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0252854 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0252739 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0252685 |
| YBX1 | Y box binding protein 1 | -0.0252363 |
