| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the XRK3F2_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.172981 |
| EGFR | epidermal growth factor receptor | 0.134309 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.10425 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0994919 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0944202 |
| RNF213 | ring finger protein 213 | 0.0848547 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0803839 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0774257 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0624186 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0601643 |
| MYOF | myoferlin | 0.0601276 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0596758 |
| B2M | beta-2-microglobulin | 0.0527162 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0524837 |
| EFNA5 | ephrin-A5 | 0.0505701 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0505114 |
| SP100 | SP100 nuclear antigen | 0.0497429 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0476172 |
| RAD51B | RAD51 paralog B | 0.0444973 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0433258 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0419852 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0419849 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0410674 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0408764 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0405866 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0399065 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0390386 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0387558 |
| RPS3 | ribosomal protein S3 | 0.0385152 |
| RPS8 | ribosomal protein S8 | 0.0369052 |
| RPS6 | ribosomal protein S6 | 0.0354462 |
| RPL31 | ribosomal protein L31 | 0.0352177 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0349919 |
| FOXP1 | forkhead box P1 | 0.0347647 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0347048 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0344965 |
| KYNU | kynureninase | 0.0338722 |
| IRS2 | insulin receptor substrate 2 | 0.0337807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0335936 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.033422 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0329541 |
| RPL35A | ribosomal protein L35a | 0.0328867 |
| RPL37A | ribosomal protein L37a | 0.0328464 |
| NTN4 | netrin 4 | 0.0325663 |
| SLTM | SAFB-like, transcription modulator | 0.0313209 |
| MX1 | MX dynamin-like GTPase 1 | 0.0303537 |
| RPS25 | ribosomal protein S25 | 0.0303012 |
| RPLP1 | ribosomal protein, large, P1 | 0.0300173 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0295898 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.029498 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0293356 |
| RPLP0 | ribosomal protein, large, P0 | 0.0291008 |
| RPS12 | ribosomal protein S12 | 0.0289964 |
| HLA-B | major histocompatibility complex, class I, B | 0.0289301 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0283323 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0282205 |
| SQSTM1 | sequestosome 1 | 0.0280975 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0278406 |
| S100P | S100 calcium binding protein P | 0.0272947 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.02704 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0267476 |
| RPL11 | ribosomal protein L11 | 0.0266149 |
| ENO1 | enolase 1, (alpha) | 0.0264781 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0264495 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0258892 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0258373 |
| KRT7 | keratin 7, type II | 0.0255153 |
| TXNRD1 | thioredoxin reductase 1 | 0.0254698 |
| RPL37 | ribosomal protein L37 | 0.0252325 |
| IFI44L | interferon-induced protein 44-like | 0.0248529 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0248414 |
| PMP22 | peripheral myelin protein 22 | 0.0242632 |
| DST | dystonin | 0.0240152 |
| HDAC9 | histone deacetylase 9 | 0.0238334 |
| FTL | ferritin, light polypeptide | 0.0238304 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0238037 |
| RPS29 | ribosomal protein S29 | 0.0236732 |
| RPL30 | ribosomal protein L30 | 0.0236448 |
| AREG | amphiregulin | 0.0236308 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0234523 |
| SMYD3 | SET and MYND domain containing 3 | 0.0234448 |
| SVIL | supervillin | 0.0233859 |
| MAP7 | microtubule-associated protein 7 | 0.0232404 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0229443 |
| PLSCR1 | phospholipid scramblase 1 | 0.022815 |
| SMAD3 | SMAD family member 3 | 0.0226227 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0223424 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0222894 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0221652 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0221247 |
| PKM | pyruvate kinase, muscle | 0.0219916 |
| GPHN | gephyrin | 0.0218949 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0218874 |
| RPS23 | ribosomal protein S23 | 0.0218632 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0217621 |
| ATF6 | activating transcription factor 6 | 0.0217274 |
| TRIM56 | tripartite motif containing 56 | 0.0216501 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0216376 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0211488 |
| RPS27A | ribosomal protein S27a | 0.0209907 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | -0.0771292 |
| H1-0 | H1.0 linker histone | -0.0556794 |
| LAMA4 | laminin, alpha 4 | -0.0544569 |
| FAM13A | family with sequence similarity 13, member A | -0.048872 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0481918 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0478448 |
| NDRG1 | N-myc downstream regulated 1 | -0.0461951 |
| CES1 | carboxylesterase 1 | -0.0455631 |
| TOP1 | topoisomerase (DNA) I | -0.0432843 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0425586 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0415299 |
| TMEM165 | transmembrane protein 165 | -0.0407967 |
| HDLBP | high density lipoprotein binding protein | -0.0401291 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0395462 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0368685 |
| MKI67 | marker of proliferation Ki-67 | -0.0367806 |
| SCEL | sciellin | -0.0365233 |
| NGLY1 | N-glycanase 1 | -0.0354827 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.032898 |
| ASPH | aspartate beta-hydroxylase | -0.0320981 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0308413 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0307069 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0301087 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0294231 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0291461 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0289948 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0284143 |
| WDR45B | WD repeat domain 45B | -0.0280032 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0269483 |
| SEPTIN2 | septin 2 | -0.0259539 |
| PRRC2C | proline-rich coiled-coil 2C | -0.025948 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0258312 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.025617 |
| WASF2 | WAS protein family, member 2 | -0.0255226 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0252326 |
| RASA2 | RAS p21 protein activator 2 | -0.0251825 |
| SRP54 | signal recognition particle 54kDa | -0.0245003 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.024479 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0234162 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0231581 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0231166 |
| LMO7 | LIM domain 7 | -0.0229695 |
| CDCP1 | CUB domain containing protein 1 | -0.0229589 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0228927 |
| OGA | O-GlcNAcase | -0.022869 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0228556 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.022814 |
| OSMR | oncostatin M receptor | -0.0226115 |
| SEPTIN10 | septin 10 | -0.0226091 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0220921 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0214759 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0214253 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.021397 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0211956 |
| RAB1A | RAB1A, member RAS oncogene family | -0.021104 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0209481 |
| RIN2 | Ras and Rab interactor 2 | -0.020901 |
| LAMB3 | laminin, beta 3 | -0.0208634 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0207453 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0206728 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0205874 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0204308 |
| SUCO | SUN domain containing ossification factor | -0.0203222 |
| SLMAP | sarcolemma associated protein | -0.0199196 |
| HYOU1 | hypoxia up-regulated 1 | -0.01982 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0194985 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0194535 |
| PUM2 | pumilio RNA-binding family member 2 | -0.019432 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0192919 |
| USP3 | ubiquitin specific peptidase 3 | -0.0192791 |
| ATP13A3 | ATPase type 13A3 | -0.0192441 |
| RTN4 | reticulon 4 | -0.0190655 |
| FLNB | filamin B, beta | -0.0190619 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0190122 |
| HELZ | helicase with zinc finger | -0.0188884 |
| TPD52 | tumor protein D52 | -0.0187376 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0185472 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0184867 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0178363 |
| MORF4L2 | mortality factor 4 like 2 | -0.0175761 |
| ECT2 | epithelial cell transforming 2 | -0.0171007 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0166727 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0165854 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0164344 |
| COPA | coatomer protein complex, subunit alpha | -0.016391 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0163279 |
| RCOR1 | REST corepressor 1 | -0.0162873 |
| RNF145 | ring finger protein 145 | -0.016217 |
| TFG | TRK-fused gene | -0.0161825 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0161197 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.015971 |
| SEC24D | SEC24 family member D | -0.0157754 |
| AHNAK | AHNAK nucleoprotein | -0.0157743 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0157721 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0156478 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0155814 |
| PYGL | phosphorylase, glycogen, liver | -0.0154804 |
| SBF2 | SET binding factor 2 | -0.0154564 |
| CLTC | clathrin, heavy chain (Hc) | -0.0153608 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0153406 |
