| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.113289 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0962263 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0903917 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0862763 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0719164 |
| RAD51B | RAD51 paralog B | 0.0704054 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0626012 |
| LAMC2 | laminin, gamma 2 | 0.0598362 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0592703 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0547022 |
| FTL | ferritin, light polypeptide | 0.0543104 |
| HLA-A | major histocompatibility complex, class I, A | 0.0527555 |
| MUC13 | mucin 13, cell surface associated | 0.0524458 |
| B2M | beta-2-microglobulin | 0.0518114 |
| LAMB3 | laminin, beta 3 | 0.0517991 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0517242 |
| ACTN4 | actinin, alpha 4 | 0.0508999 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0508669 |
| KIF5B | kinesin family member 5B | 0.0505103 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0494774 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0492169 |
| LAMA4 | laminin, alpha 4 | 0.0487316 |
| HMGA2 | high mobility group AT-hook 2 | 0.0476307 |
| FMNL2 | formin-like 2 | 0.0470467 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0462 |
| PTMA | prothymosin, alpha | 0.0461882 |
| VCL | vinculin | 0.0460493 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0445755 |
| GPHN | gephyrin | 0.0441026 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0438771 |
| METTL15 | methyltransferase like 15 | 0.0421211 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0412868 |
| SDCBP | syndecan binding protein (syntenin) | 0.0412538 |
| MYO1E | myosin IE | 0.0411753 |
| RAB10 | RAB10, member RAS oncogene family | 0.0409076 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.040377 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0399089 |
| DENND1A | DENN/MADD domain containing 1A | 0.0399018 |
| LMO7 | LIM domain 7 | 0.0394426 |
| SQSTM1 | sequestosome 1 | 0.0390571 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0390276 |
| BCL2L1 | BCL2-like 1 | 0.0389229 |
| JUN | jun proto-oncogene | 0.0388045 |
| RPL26 | ribosomal protein L26 | 0.0387524 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0386537 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0383037 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0378785 |
| TLK1 | tousled-like kinase 1 | 0.037878 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0373155 |
| MYO10 | myosin X | 0.037113 |
| USP47 | ubiquitin specific peptidase 47 | 0.0369985 |
| SMYD3 | SET and MYND domain containing 3 | 0.0368855 |
| FAM13A | family with sequence similarity 13, member A | 0.036858 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0366673 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0364119 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0363652 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0361999 |
| FNBP4 | formin binding protein 4 | 0.0360113 |
| PRDM1 | PR domain containing 1, with ZNF domain | 0.0357652 |
| GRAMD1B | GRAM domain containing 1B | 0.0356229 |
| STEAP4 | STEAP family member 4 | 0.0351378 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0350389 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0348619 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0348587 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0343946 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0341751 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.033914 |
| RORA | RAR-related orphan receptor A | 0.0338405 |
| LSAMP | limbic system-associated membrane protein | 0.033774 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0337473 |
| EGR1 | early growth response 1 | 0.0336895 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0333176 |
| INHBA | inhibin, beta A | 0.0329743 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0328993 |
| MLEC | malectin | 0.0327064 |
| FBXO32 | F-box protein 32 | 0.032492 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.032464 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0324064 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0320184 |
| RIGI | RNA sensor RIG-I | 0.0316685 |
| FRY | furry homolog (Drosophila) | 0.031089 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0309477 |
| ZFHX3 | zinc finger homeobox 3 | 0.0307586 |
| FHIT | fragile histidine triad | 0.0307473 |
| PTK2 | protein tyrosine kinase 2 | 0.0306662 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0306209 |
| DTNA | dystrobrevin, alpha | 0.0304498 |
| KYNU | kynureninase | 0.0303666 |
| RAI14 | retinoic acid induced 14 | 0.0303255 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0302534 |
| RPL8 | ribosomal protein L8 | 0.0302364 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0302346 |
| ERBIN | erbb2 interacting protein | 0.0302069 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0302013 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0301425 |
| ATG14 | autophagy related 14 | 0.030009 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0298419 |
| REEP3 | receptor accessory protein 3 | 0.0298086 |
| RNF149 | ring finger protein 149 | 0.0297322 |
| RPL38 | ribosomal protein L38 | 0.0296994 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.17074 |
| KRT17 | keratin 17, type I | -0.161686 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.146529 |
| ANXA2 | annexin A2 | -0.13737 |
| VIM | vimentin | -0.126454 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.118825 |
| NDRG1 | N-myc downstream regulated 1 | -0.113368 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.105944 |
| IGF2 | insulin-like growth factor 2 | -0.0984481 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0921554 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0869799 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0709829 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0707567 |
| TMSB10 | thymosin beta 10 | -0.0679779 |
| SLMAP | sarcolemma associated protein | -0.0668985 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0659805 |
| FN1 | fibronectin 1 | -0.0659584 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0646867 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.062067 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0618884 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0617938 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0608413 |
| FLNB | filamin B, beta | -0.0585154 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0583525 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.058055 |
| RUNX1 | runt-related transcription factor 1 | -0.0563157 |
| COPA | coatomer protein complex, subunit alpha | -0.0557143 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0547519 |
| ACTG1 | actin gamma 1 | -0.0527787 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0523871 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0521567 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0511425 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0505414 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0499495 |
| ASPH | aspartate beta-hydroxylase | -0.0495469 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0494657 |
| PGK1 | phosphoglycerate kinase 1 | -0.0486605 |
| QKI | QKI, KH domain containing, RNA binding | -0.0486381 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0478673 |
| RPS6 | ribosomal protein S6 | -0.0477527 |
| CANX | calnexin | -0.0475177 |
| ATXN1 | ataxin 1 | -0.0459164 |
| ENO1 | enolase 1, (alpha) | -0.0455046 |
| EZR | ezrin | -0.0454303 |
| CALU | calumenin | -0.0449676 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0443856 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0440199 |
| SRPK2 | SRSF protein kinase 2 | -0.0429205 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0428306 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0425914 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.042338 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0423186 |
| TPM4 | tropomyosin 4 | -0.042178 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0419175 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0417395 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0417279 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0416656 |
| RPL11 | ribosomal protein L11 | -0.0409998 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0409906 |
| PKM | pyruvate kinase, muscle | -0.0408144 |
| PHF21A | PHD finger protein 21A | -0.0407684 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0406448 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0404963 |
| CYTH1 | cytohesin 1 | -0.0404207 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0403833 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0402379 |
| RPL19 | ribosomal protein L19 | -0.0402068 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.040161 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0397941 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0391551 |
| CDH13 | cadherin 13 | -0.0391514 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0389519 |
| RPL32 | ribosomal protein L32 | -0.0385799 |
| MUC16 | mucin 16, cell surface associated | -0.0380207 |
| RPLP0 | ribosomal protein, large, P0 | -0.0380018 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0379461 |
| TOP1 | topoisomerase (DNA) I | -0.0379265 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0376528 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0373358 |
| RPL34 | ribosomal protein L34 | -0.0372852 |
| RTN4 | reticulon 4 | -0.0372081 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0366957 |
| LAMB1 | laminin, beta 1 | -0.0365743 |
| MEF2A | myocyte enhancer factor 2A | -0.03636 |
| ANXA1 | annexin A1 | -0.0360478 |
| CCDC6 | coiled-coil domain containing 6 | -0.0359817 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0357991 |
| HBP1 | HMG-box transcription factor 1 | -0.0355002 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0354104 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0350911 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0350536 |
| RBM5 | RNA binding motif protein 5 | -0.0342643 |
| GDF15 | growth differentiation factor 15 | -0.0340837 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0340832 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0338812 |
| S100A9 | S100 calcium binding protein A9 | -0.0338215 |
| GPC6 | glypican 6 | -0.0338119 |
| RPL9 | ribosomal protein L9 | -0.0338067 |
| CLINT1 | clathrin interactor 1 | -0.033781 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0337115 |
