| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.128107 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.104254 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0985623 |
| FOXP2 | forkhead box P2 | 0.0948556 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.080746 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0779027 |
| CADM2 | cell adhesion molecule 2 | 0.0727324 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0716657 |
| CDH19 | cadherin 19, type 2 | 0.065212 |
| MEIS2 | Meis homeobox 2 | 0.0618943 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.059883 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0585594 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0573046 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0563512 |
| MPG | N-methylpurine-DNA glycosylase | 0.0523005 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0486744 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0466624 |
| MKI67 | marker of proliferation Ki-67 | 0.0461469 |
| PDGFC | platelet derived growth factor C | 0.0458082 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0449938 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0443724 |
| LRRC4C | leucine rich repeat containing 4C | 0.0439773 |
| RPS8 | ribosomal protein S8 | 0.0433006 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0429946 |
| NTM | neurotrimin | 0.0427283 |
| RAD51B | RAD51 paralog B | 0.0415419 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0415215 |
| RPS16 | ribosomal protein S16 | 0.0413405 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0412992 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0407609 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0396145 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0388006 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0386874 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0381634 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0377424 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0376636 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0369914 |
| WWC2 | WW and C2 domain containing 2 | 0.0369229 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0365159 |
| SPIDR | scaffolding protein involved in DNA repair | 0.036157 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0358825 |
| EXOC6B | exocyst complex component 6B | 0.0350336 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0345601 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0343297 |
| KIF4A | kinesin family member 4A | 0.0340686 |
| PGPEP1L | pyroglutamyl-peptidase I-like | 0.0340085 |
| PHIP | pleckstrin homology domain interacting protein | 0.0335682 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0325333 |
| CENPF | centromere protein F, 350/400kDa | 0.0315336 |
| FBXO17 | F-box protein 17 | 0.0314877 |
| GPC3 | glypican 3 | 0.0314707 |
| ACTG1 | actin gamma 1 | 0.0310002 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0308748 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0307957 |
| TENM3 | teneurin transmembrane protein 3 | 0.0306564 |
| RPL35A | ribosomal protein L35a | 0.0306481 |
| VCL | vinculin | 0.0306395 |
| TBCA | tubulin folding cofactor A | 0.0305883 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0298274 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0296463 |
| PRKD1 | protein kinase D1 | 0.0294498 |
| BNC2 | basonuclin 2 | 0.029306 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0292436 |
| MAP4 | microtubule-associated protein 4 | 0.0287663 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.02874 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0285066 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.0283707 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0281869 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0277903 |
| METAP2 | methionyl aminopeptidase 2 | 0.0277586 |
| RPLP0 | ribosomal protein, large, P0 | 0.0276812 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0267171 |
| DST | dystonin | 0.0264536 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0262851 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0260817 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0259033 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.025839 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0255399 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0255023 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0251006 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0250813 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.024955 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0248358 |
| DICER1 | dicer 1, ribonuclease type III | 0.0246364 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.024454 |
| PPHLN1 | periphilin 1 | 0.0243651 |
| INTS6 | integrator complex subunit 6 | 0.0243336 |
| RPL31 | ribosomal protein L31 | 0.0243205 |
| HDAC8 | histone deacetylase 8 | 0.0242381 |
| PARD3 | par-3 family cell polarity regulator | 0.0239265 |
| RPS23 | ribosomal protein S23 | 0.0239259 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0239097 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0238461 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0238164 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0238029 |
| B2M | beta-2-microglobulin | 0.0237322 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0236775 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0236741 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0236493 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0236385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PGAP1 | post-GPI attachment to proteins 1 | -0.129669 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0944185 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0812044 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0809024 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0789927 |
| ZNF292 | zinc finger protein 292 | -0.0708959 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0683578 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0682218 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0676988 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.066597 |
| SRP54 | signal recognition particle 54kDa | -0.0619795 |
| RAI1 | retinoic acid induced 1 | -0.0609143 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0606824 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0600529 |
| ITGAV | integrin, alpha V | -0.0572513 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0559465 |
| PCDH9 | protocadherin 9 | -0.0526229 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0504355 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0499226 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0496646 |
| PTMA | prothymosin, alpha | -0.0496115 |
| GOLGA4 | golgin A4 | -0.0495955 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0489847 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.048777 |
| NHSL1 | NHS-like 1 | -0.0480582 |
| PEG10 | paternally expressed 10 | -0.0479863 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0479035 |
| TMSB4X | thymosin beta 4, X-linked | -0.0457884 |
| MED13L | mediator complex subunit 13-like | -0.0456025 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0443745 |
| USP53 | ubiquitin specific peptidase 53 | -0.0434403 |
| NRG1 | neuregulin 1 | -0.043118 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.043111 |
| PCDH7 | protocadherin 7 | -0.0429422 |
| SETD5 | SET domain containing 5 | -0.0428907 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0420842 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0415833 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.039367 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0393564 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0387252 |
| OLA1 | Obg-like ATPase 1 | -0.0386768 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0385769 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.038317 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0377507 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0375273 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.03751 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0368334 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0367548 |
| PFN1 | profilin 1 | -0.0365391 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0362445 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0360241 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0351504 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0348877 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0348795 |
| QKI | QKI, KH domain containing, RNA binding | -0.0342369 |
| COL5A2 | collagen, type V, alpha 2 | -0.0340306 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0335243 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0334831 |
| POTEF | POTE ankyrin domain family, member F | -0.0332828 |
| RTN4 | reticulon 4 | -0.0331157 |
| URI1 | URI1, prefoldin-like chaperone | -0.0329673 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0326109 |
| CDC73 | cell division cycle 73 | -0.0323088 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0321094 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0319676 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0319532 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0318594 |
| PRTG | protogenin | -0.0316886 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0315102 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0313077 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0312215 |
| CCDC88A | coiled-coil domain containing 88A | -0.0310754 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0310498 |
| PRR16 | proline rich 16 | -0.0310246 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0307092 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0305494 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0300798 |
| MYO10 | myosin X | -0.030022 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0296586 |
| H1-0 | H1.0 linker histone | -0.0296122 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0294642 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0287621 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0278884 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | -0.027792 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0277538 |
| SEPTIN7 | septin 7 | -0.0277321 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0276274 |
| FBXO11 | F-box protein 11 | -0.0276026 |
| COL1A2 | collagen, type I, alpha 2 | -0.0275586 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0275433 |
| HMGB1 | high mobility group box 1 | -0.0273811 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0272966 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0271705 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0271342 |
| CAVIN1 | caveolae associated protein 1 | -0.0270008 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0269246 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0267553 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0266536 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0264787 |
| SUCO | SUN domain containing ossification factor | -0.0262977 |
