| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.381813 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.24579 |
| HDAC9 | histone deacetylase 9 | 0.174825 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.157163 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.11973 |
| SLC38A2 | solute carrier family 38, member 2 | 0.114986 |
| RPS6 | ribosomal protein S6 | 0.103882 |
| EGFR | epidermal growth factor receptor | 0.0925046 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0853256 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0842801 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0821584 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0800544 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0797707 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0786398 |
| RPL31 | ribosomal protein L31 | 0.0783602 |
| RPS8 | ribosomal protein S8 | 0.0731409 |
| RPS13 | ribosomal protein S13 | 0.0717705 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0699534 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0662526 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0660066 |
| HSPB1 | heat shock 27kDa protein 1 | 0.065459 |
| RPS23 | ribosomal protein S23 | 0.0600102 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0592875 |
| MACROD2 | MACRO domain containing 2 | 0.058499 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0561935 |
| RPL36 | ribosomal protein L36 | 0.0552676 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0542269 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0519979 |
| PDGFC | platelet derived growth factor C | 0.0511112 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0506518 |
| RPL9 | ribosomal protein L9 | 0.050086 |
| RPL19 | ribosomal protein L19 | 0.0498573 |
| DIAPH3 | diaphanous-related formin 3 | 0.0495986 |
| RPL37A | ribosomal protein L37a | 0.0475219 |
| B2M | beta-2-microglobulin | 0.0458313 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.045736 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0449967 |
| MYOF | myoferlin | 0.0448544 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0440508 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0423692 |
| ACTG1 | actin gamma 1 | 0.0417994 |
| RPL7 | ribosomal protein L7 | 0.0414249 |
| RPL11 | ribosomal protein L11 | 0.0408473 |
| RPL7A | ribosomal protein L7a | 0.0386039 |
| POTEF | POTE ankyrin domain family, member F | 0.0380214 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 0.0375193 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0368168 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0367571 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0366843 |
| FTL | ferritin, light polypeptide | 0.0364987 |
| RPS25 | ribosomal protein S25 | 0.0360608 |
| GSE1 | Gse1 coiled-coil protein | 0.0356164 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0354088 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0352258 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.035109 |
| RPL23 | ribosomal protein L23 | 0.0350985 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0343718 |
| LDHB | lactate dehydrogenase B | 0.0342961 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0336205 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.0335976 |
| MLIP | muscular LMNA-interacting protein | 0.0334142 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0331754 |
| EVI5 | ecotropic viral integration site 5 | 0.0325042 |
| RPS3 | ribosomal protein S3 | 0.0323459 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0321315 |
| RPL12 | ribosomal protein L12 | 0.0313165 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0308426 |
| RPS10 | ribosomal protein S10 | 0.0306072 |
| RPLP2 | ribosomal protein, large, P2 | 0.0306039 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0302719 |
| NMD3 | NMD3 ribosome export adaptor | 0.0302021 |
| PLCE1 | phospholipase C, epsilon 1 | 0.0300411 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0298945 |
| EFNA5 | ephrin-A5 | 0.0295006 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0292997 |
| DSTN | destrin (actin depolymerizing factor) | 0.0292706 |
| RPS11 | ribosomal protein S11 | 0.0290862 |
| RPLP0 | ribosomal protein, large, P0 | 0.0289833 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0287852 |
| PCBP2 | poly(rC) binding protein 2 | 0.0285321 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0284427 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0277849 |
| BPTF | bromodomain PHD finger transcription factor | 0.0275379 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0273532 |
| FHIT | fragile histidine triad | 0.0272165 |
| RPS27A | ribosomal protein S27a | 0.0268273 |
| MT2A | metallothionein 2A | 0.0266258 |
| RACK1 | receptor for activated C kinase 1 | 0.025971 |
| TJP1 | tight junction protein 1 | 0.0257867 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0257186 |
| GLI2 | GLI family zinc finger 2 | 0.0255908 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0255475 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0253167 |
| S100A10 | S100 calcium binding protein A10 | 0.0252547 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0252345 |
| SUMF1 | sulfatase modifying factor 1 | 0.0249072 |
| ENO1 | enolase 1, (alpha) | 0.0248734 |
| FNIP1 | folliculin interacting protein 1 | 0.0248301 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0248048 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0247658 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.135175 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.108889 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0885797 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0843302 |
| VCL | vinculin | -0.0796446 |
| TMSB4X | thymosin beta 4, X-linked | -0.0683875 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.065623 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0632291 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0625306 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0519946 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0428202 |
| GOLGA4 | golgin A4 | -0.0421643 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0406756 |
| BMP10 | bone morphogenetic protein 10 | -0.040313 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0358403 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0351989 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.034951 |
| FOXP1 | forkhead box P1 | -0.0321976 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0319774 |
| PRELID2 | PRELI domain containing 2 | -0.0312522 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0306035 |
| HJURP | Holliday junction recognition protein | -0.0301303 |
| NUP58 | nucleoporin 58 | -0.0287941 |
| S100A6 | S100 calcium binding protein A6 | -0.028732 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0284652 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0276555 |
| TFG | TRK-fused gene | -0.0276422 |
| FBXO11 | F-box protein 11 | -0.0274123 |
| ECT2 | epithelial cell transforming 2 | -0.0270132 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0259841 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0256594 |
| SEC24D | SEC24 family member D | -0.0255664 |
| SBF2 | SET binding factor 2 | -0.0252311 |
| MKI67 | marker of proliferation Ki-67 | -0.0250126 |
| RRBP1 | ribosome binding protein 1 | -0.0242856 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0241922 |
| LOXL3 | lysyl oxidase-like 3 | -0.0240878 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.024002 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0238866 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0237952 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0236974 |
| AHNAK | AHNAK nucleoprotein | -0.0234078 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0231586 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0229949 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0229406 |
| DNMBP | dynamin binding protein | -0.0225677 |
| PFN1 | profilin 1 | -0.0219351 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0218513 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0217793 |
| RRM2 | ribonucleotide reductase M2 | -0.0216737 |
| SRPK2 | SRSF protein kinase 2 | -0.0216027 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0216007 |
| INTS6 | integrator complex subunit 6 | -0.021468 |
| DUSP6 | dual specificity phosphatase 6 | -0.0213596 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0213515 |
| CDC73 | cell division cycle 73 | -0.0213404 |
| USP3 | ubiquitin specific peptidase 3 | -0.0212902 |
| TOP1 | topoisomerase (DNA) I | -0.0212633 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.021221 |
| COPA | coatomer protein complex, subunit alpha | -0.0209301 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0207902 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0207768 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0203237 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0196695 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0193432 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0191611 |
| SCFD1 | sec1 family domain containing 1 | -0.0191491 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0189763 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0186794 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0186688 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0186565 |
| PKM | pyruvate kinase, muscle | -0.0186041 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0185184 |
| FLNB | filamin B, beta | -0.0184218 |
| RTN3 | reticulon 3 | -0.0183809 |
| CKAP5 | cytoskeleton associated protein 5 | -0.018301 |
| CCDC88A | coiled-coil domain containing 88A | -0.0181292 |
| RBM25 | RNA binding motif protein 25 | -0.0179725 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.017808 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.017781 |
| MORF4L2 | mortality factor 4 like 2 | -0.0177708 |
| USP34 | ubiquitin specific peptidase 34 | -0.0176881 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0176814 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0176733 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0176286 |
| TPD52 | tumor protein D52 | -0.0176139 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0175462 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0175283 |
| KIAA1958 | KIAA1958 | -0.0175016 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.017478 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.017356 |
| RTN4 | reticulon 4 | -0.0172744 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0172474 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0169842 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0168555 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.01677 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.016657 |
| RBM26 | RNA binding motif protein 26 | -0.0165742 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.0165324 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0165251 |
