| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.19451 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.117448 |
| HIP1 | huntingtin interacting protein 1 | 0.10839 |
| VIM | vimentin | 0.108189 |
| CD44 | CD44 molecule (Indian blood group) | 0.0885542 |
| AHNAK | AHNAK nucleoprotein | 0.0852463 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0827633 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0826531 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0780274 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0759151 |
| UBC | ubiquitin C | 0.0750308 |
| KYNU | kynureninase | 0.0746375 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0653956 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0618642 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0591284 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0514933 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0486374 |
| AOPEP | aminopeptidase O (putative) | 0.0483534 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0477382 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0475903 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0471108 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0456699 |
| THBS1 | thrombospondin 1 | 0.0448981 |
| ANXA2 | annexin A2 | 0.0446388 |
| RND3 | Rho family GTPase 3 | 0.0442164 |
| MAP1B | microtubule-associated protein 1B | 0.0418283 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0410884 |
| PRELID2 | PRELI domain containing 2 | 0.0410719 |
| NRXN3 | neurexin 3 | 0.0409517 |
| AHR | aryl hydrocarbon receptor | 0.0407612 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0397262 |
| LDHA | lactate dehydrogenase A | 0.0394834 |
| FNIP1 | folliculin interacting protein 1 | 0.0389994 |
| FN1 | fibronectin 1 | 0.0384759 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0369608 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0355202 |
| TNS3 | tensin 3 | 0.0341429 |
| HDAC9 | histone deacetylase 9 | 0.0338123 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0329431 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0328496 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0324852 |
| ZNF395 | zinc finger protein 395 | 0.0323798 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0319311 |
| H3-3B | H3.3 histone B | 0.0311236 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0309885 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0308526 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0301187 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0291368 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0286237 |
| HLA-A | major histocompatibility complex, class I, A | 0.0284056 |
| FMNL2 | formin-like 2 | 0.0283074 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0282639 |
| PKM | pyruvate kinase, muscle | 0.0281031 |
| LOX | lysyl oxidase | 0.0278392 |
| CALD1 | caldesmon 1 | 0.0271751 |
| AUTS2 | autism susceptibility candidate 2 | 0.0270023 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.026359 |
| SDC2 | syndecan 2 | 0.0261777 |
| ARMC9 | armadillo repeat containing 9 | 0.0261141 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0260767 |
| MYO9A | myosin IXA | 0.0258411 |
| STAG2 | stromal antigen 2 | 0.0257043 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0251502 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0251301 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0249204 |
| GOLGB1 | golgin B1 | 0.0247723 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0244694 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0244166 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.024337 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.024172 |
| CDK6 | cyclin-dependent kinase 6 | 0.0239673 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0235983 |
| FNDC3A | fibronectin type III domain containing 3A | 0.023591 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0235561 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0235421 |
| SQSTM1 | sequestosome 1 | 0.0233853 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0230718 |
| TXNIP | thioredoxin interacting protein | 0.023016 |
| CUL4B | cullin 4B | 0.0229745 |
| HLA-B | major histocompatibility complex, class I, B | 0.0229491 |
| IL6ST | interleukin 6 signal transducer | 0.0227491 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0225454 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0225432 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0223731 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0219378 |
| RPLP0 | ribosomal protein, large, P0 | 0.0218075 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.021771 |
| RACK1 | receptor for activated C kinase 1 | 0.0216658 |
| PMM2 | phosphomannomutase 2 | 0.021549 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0215221 |
| OPTN | optineurin | 0.0214762 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0214025 |
| SYNJ2 | synaptojanin 2 | 0.021379 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0213233 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0210893 |
| SSH1 | slingshot protein phosphatase 1 | 0.0209684 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0209676 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.020902 |
| TLN1 | talin 1 | 0.0208356 |
| SP100 | SP100 nuclear antigen | 0.0206528 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.182818 |
| TMSB10 | thymosin beta 10 | -0.138423 |
| CDH13 | cadherin 13 | -0.117818 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0949052 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0885627 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0723329 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0661086 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0648491 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0543401 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0533135 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.05276 |
| EFNA5 | ephrin-A5 | -0.0512412 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0495313 |
| VEGFA | vascular endothelial growth factor A | -0.0493275 |
| NDRG1 | N-myc downstream regulated 1 | -0.0485235 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0480323 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0455584 |
| EGFR | epidermal growth factor receptor | -0.044899 |
| ASPH | aspartate beta-hydroxylase | -0.041883 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0404697 |
| SEC24D | SEC24 family member D | -0.0395343 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0394245 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0386568 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0386506 |
| IL6 | interleukin 6 | -0.0383158 |
| LMNA | lamin A/C | -0.038156 |
| RRBP1 | ribosome binding protein 1 | -0.0381171 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0371369 |
| COL5A1 | collagen, type V, alpha 1 | -0.0364083 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0361766 |
| POTEF | POTE ankyrin domain family, member F | -0.0359301 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0347725 |
| DST | dystonin | -0.0346439 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0339135 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0337458 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0332376 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0327931 |
| VCL | vinculin | -0.0317168 |
| COL1A1 | collagen, type I, alpha 1 | -0.0317122 |
| NBAS | neuroblastoma amplified sequence | -0.0312691 |
| COG6 | component of oligomeric golgi complex 6 | -0.0312597 |
| PTMA | prothymosin, alpha | -0.030622 |
| XPO1 | exportin 1 | -0.0303671 |
| GNAS | GNAS complex locus | -0.0292937 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0287671 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0286449 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0278766 |
| EGR1 | early growth response 1 | -0.0275661 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0273079 |
| USP34 | ubiquitin specific peptidase 34 | -0.0268317 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0265643 |
| HM13 | histocompatibility (minor) 13 | -0.0265312 |
| COL1A2 | collagen, type I, alpha 2 | -0.0264225 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0257864 |
| SETD5 | SET domain containing 5 | -0.0256699 |
| SEPTIN2 | septin 2 | -0.0252804 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0251799 |
| USP37 | ubiquitin specific peptidase 37 | -0.0250105 |
| SEC24A | SEC24 family member A | -0.0249972 |
| RASAL2 | RAS protein activator like 2 | -0.0247187 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0246586 |
| FUS | FUS RNA binding protein | -0.0246464 |
| SUCO | SUN domain containing ossification factor | -0.024639 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0244116 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0243049 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0242624 |
| CTBP2 | C-terminal binding protein 2 | -0.0240081 |
| TOP1 | topoisomerase (DNA) I | -0.0238518 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.023845 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0238273 |
| RBM25 | RNA binding motif protein 25 | -0.0236962 |
| MLEC | malectin | -0.0234027 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0233662 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0231931 |
| COL5A2 | collagen, type V, alpha 2 | -0.0231876 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0231672 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0230636 |
| NUP98 | nucleoporin 98kDa | -0.0226733 |
| MCL1 | myeloid cell leukemia 1 | -0.0225503 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0224832 |
| COPA | coatomer protein complex, subunit alpha | -0.0224825 |
| HLA-C | major histocompatibility complex, class I, C | -0.0224753 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.022328 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0222824 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0221691 |
| SMYD3 | SET and MYND domain containing 3 | -0.0218554 |
| FLNA | filamin A, alpha | -0.0217595 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0215995 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0215578 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0214353 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0214324 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.021414 |
| ARRDC3 | arrestin domain containing 3 | -0.0210283 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0209498 |
| RBM33 | RNA binding motif protein 33 | -0.020862 |
| CADM1 | cell adhesion molecule 1 | -0.0208555 |
| TMEM263 | transmembrane protein 263 | -0.0207862 |
| XPO6 | exportin 6 | -0.0205897 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.0204723 |
| TPM3 | tropomyosin 3 | -0.0199746 |
