| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.105552 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0993966 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0943282 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0896645 |
| RIGI | RNA sensor RIG-I | 0.0866558 |
| PRKCA | protein kinase C, alpha | 0.085879 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0774309 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0752084 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0739044 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0733116 |
| INTS6 | integrator complex subunit 6 | 0.0732148 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0724143 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0714568 |
| SMYD3 | SET and MYND domain containing 3 | 0.0685452 |
| LDHA | lactate dehydrogenase A | 0.0644893 |
| SVIL | supervillin | 0.0596546 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0531049 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0529919 |
| DST | dystonin | 0.0529681 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.049239 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.049062 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0488196 |
| RORA | RAR-related orphan receptor A | 0.046912 |
| CD44 | CD44 molecule (Indian blood group) | 0.0459894 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0444339 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0411833 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0405773 |
| FNDC3B | fibronectin type III domain containing 3B | 0.040489 |
| SQSTM1 | sequestosome 1 | 0.0401928 |
| ATM | ATM serine/threonine kinase | 0.0393833 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0385526 |
| OSMR | oncostatin M receptor | 0.0377956 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0368806 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0357512 |
| PRR16 | proline rich 16 | 0.0356849 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0346314 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0344757 |
| B2M | beta-2-microglobulin | 0.034341 |
| AHNAK | AHNAK nucleoprotein | 0.0338144 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0330532 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0330179 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0328136 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0323996 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0316607 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.031611 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0311403 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.031124 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0308529 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0307422 |
| ITGAV | integrin, alpha V | 0.0305814 |
| CUX1 | cut-like homeobox 1 | 0.0297457 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0296409 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0294977 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.029441 |
| SIK2 | salt-inducible kinase 2 | 0.0289078 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0287503 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0285773 |
| PCED1B | PC-esterase domain containing 1B | 0.0285105 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0270918 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0270446 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0267377 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0266649 |
| RAD51B | RAD51 paralog B | 0.0265707 |
| SMAD3 | SMAD family member 3 | 0.0265533 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.026301 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0261204 |
| MED13L | mediator complex subunit 13-like | 0.0257775 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0257196 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0252718 |
| COL5A1 | collagen, type V, alpha 1 | 0.0250926 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0250543 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0247889 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0246939 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.024434 |
| WWOX | WW domain containing oxidoreductase | 0.0240582 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0240318 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0240268 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0238181 |
| AHR | aryl hydrocarbon receptor | 0.0238113 |
| TMEM135 | transmembrane protein 135 | 0.0237266 |
| AEBP2 | AE binding protein 2 | 0.0237112 |
| RANBP17 | RAN binding protein 17 | 0.0236337 |
| GOLGB1 | golgin B1 | 0.0235186 |
| CDYL | chromodomain protein, Y-like | 0.0231486 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0229846 |
| TAPBP | TAP binding protein (tapasin) | 0.0229467 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0229346 |
| ANKRD28 | ankyrin repeat domain 28 | 0.022815 |
| MMP24OS | MMP24 opposite strand | 0.0225758 |
| RAB31 | RAB31, member RAS oncogene family | 0.0225186 |
| MYO1D | myosin ID | 0.0225025 |
| ANO6 | anoctamin 6 | 0.0225015 |
| HMGA2 | high mobility group AT-hook 2 | 0.0224057 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0223487 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0223068 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0222929 |
| THBS1 | thrombospondin 1 | 0.02218 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0221283 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0221204 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0219746 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0721714 |
| YBX3 | Y box binding protein 3 | -0.0604623 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0557858 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0549086 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0519643 |
| SNX14 | sorting nexin 14 | -0.0491832 |
| DEK | DEK proto-oncogene | -0.0474205 |
| ASPH | aspartate beta-hydroxylase | -0.0464831 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0458791 |
| RBM39 | RNA binding motif protein 39 | -0.0453251 |
| TPX2 | TPX2, microtubule-associated | -0.0440651 |
| VIM | vimentin | -0.0423225 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0416785 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.041383 |
| TMSB10 | thymosin beta 10 | -0.0413578 |
| NUP58 | nucleoporin 58 | -0.041316 |
| DTNA | dystrobrevin, alpha | -0.0404219 |
| ANLN | anillin, actin binding protein | -0.0402219 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0399293 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0392908 |
| EGR1 | early growth response 1 | -0.0388032 |
| DIAPH3 | diaphanous-related formin 3 | -0.0376489 |
| MSN | moesin | -0.0370941 |
| CAPRIN2 | caprin family member 2 | -0.0366107 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0362977 |
| DNER | delta/notch-like EGF repeat containing | -0.0349848 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0346552 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0330422 |
| MKI67 | marker of proliferation Ki-67 | -0.0325939 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0322016 |
| GOLGA2 | golgin A2 | -0.0320132 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0316826 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0316821 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0314852 |
| HMGB1 | high mobility group box 1 | -0.0312457 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0311454 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0308743 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0305076 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0298921 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0287685 |
| PRRC2C | proline-rich coiled-coil 2C | -0.028247 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0282182 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0279622 |
| WDR45B | WD repeat domain 45B | -0.0278099 |
| MT2A | metallothionein 2A | -0.0277933 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.027683 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0272623 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0272311 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0272018 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0271421 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0271048 |
| NDRG1 | N-myc downstream regulated 1 | -0.0269328 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0268526 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.026814 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0267959 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0265456 |
| HJURP | Holliday junction recognition protein | -0.02627 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0260559 |
| NF1 | neurofibromin 1 | -0.0260462 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0259968 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0252787 |
| KIF5B | kinesin family member 5B | -0.0252155 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0249067 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0246172 |
| TPM3 | tropomyosin 3 | -0.0243742 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0241894 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0241241 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0239451 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0237876 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0236835 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0235101 |
| SFXN1 | sideroflexin 1 | -0.0235099 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0234682 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0234423 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0233608 |
| SEPTIN2 | septin 2 | -0.02333 |
| MORF4L2 | mortality factor 4 like 2 | -0.0232491 |
| PRR11 | proline rich 11 | -0.0232427 |
| LMO7 | LIM domain 7 | -0.0230889 |
| SEPTIN7 | septin 7 | -0.0230165 |
| RPL35A | ribosomal protein L35a | -0.0229471 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0226718 |
| PFN1 | profilin 1 | -0.0225935 |
| S100A9 | S100 calcium binding protein A9 | -0.0223555 |
| RBM25 | RNA binding motif protein 25 | -0.0223472 |
| HDLBP | high density lipoprotein binding protein | -0.0222327 |
| SPAG9 | sperm associated antigen 9 | -0.022004 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0219183 |
| RPL37A | ribosomal protein L37a | -0.0218018 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0216285 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0215685 |
| MCL1 | myeloid cell leukemia 1 | -0.0214788 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0214363 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0213717 |
| RPL37 | ribosomal protein L37 | -0.0212848 |
| RPS3 | ribosomal protein S3 | -0.0210918 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.020976 |
| SEC24A | SEC24 family member A | -0.0209409 |
| CCDC47 | coiled-coil domain containing 47 | -0.0207385 |
| MATR3 | matrin 3 | -0.0206432 |
