| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | XRK3F2 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the XRK3F2_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.243674 |
| EXT1 | exostosin glycosyltransferase 1 | 0.159693 |
| SQSTM1 | sequestosome 1 | 0.143814 |
| FTL | ferritin, light polypeptide | 0.0944158 |
| STC2 | stanniocalcin 2 | 0.0836586 |
| PALLD | palladin, cytoskeletal associated protein | 0.0603039 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0600066 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.059679 |
| B2M | beta-2-microglobulin | 0.0592612 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0592464 |
| HLA-B | major histocompatibility complex, class I, B | 0.057919 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0563818 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0518156 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0490617 |
| RPL31 | ribosomal protein L31 | 0.0489213 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.048406 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0474799 |
| INTS6 | integrator complex subunit 6 | 0.0467984 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0456773 |
| SFTPA2 | surfactant protein A2 | 0.0434504 |
| NTN4 | netrin 4 | 0.0428764 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0406372 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0403786 |
| RASAL2 | RAS protein activator like 2 | 0.03964 |
| TNS3 | tensin 3 | 0.0394098 |
| ENAH | enabled homolog (Drosophila) | 0.0384013 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0382569 |
| AEBP2 | AE binding protein 2 | 0.0375658 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0367261 |
| RANBP17 | RAN binding protein 17 | 0.0359126 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0347746 |
| HLA-A | major histocompatibility complex, class I, A | 0.0338395 |
| ATF6 | activating transcription factor 6 | 0.0338153 |
| TGFB2 | transforming growth factor, beta 2 | 0.0330328 |
| TMSB10 | thymosin beta 10 | 0.032874 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0314961 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0308388 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0307763 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0306416 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0302792 |
| FBN1 | fibrillin 1 | 0.0302721 |
| GLIS3 | GLIS family zinc finger 3 | 0.0302027 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0299145 |
| NXN | nucleoredoxin | 0.0293267 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0291767 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0288114 |
| ACTG1 | actin gamma 1 | 0.0278345 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0277183 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0275895 |
| AOPEP | aminopeptidase O (putative) | 0.0274293 |
| VCL | vinculin | 0.0272567 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.027111 |
| PLIN2 | perilipin 2 | 0.0269613 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0269128 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0262992 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0258863 |
| RPL9 | ribosomal protein L9 | 0.025627 |
| RAB31 | RAB31, member RAS oncogene family | 0.0252894 |
| SYT1 | synaptotagmin I | 0.0245127 |
| RACK1 | receptor for activated C kinase 1 | 0.0245011 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0241673 |
| RPS29 | ribosomal protein S29 | 0.0237059 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0230518 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0229608 |
| AHI1 | Abelson helper integration site 1 | 0.0225626 |
| RPS23 | ribosomal protein S23 | 0.0224848 |
| RPS11 | ribosomal protein S11 | 0.0223822 |
| RNF213 | ring finger protein 213 | 0.0222555 |
| DENND5B | DENN/MADD domain containing 5B | 0.0221001 |
| KLHL5 | kelch-like family member 5 | 0.0219288 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0217356 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0216531 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0212671 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0211739 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.0211327 |
| GPC6 | glypican 6 | 0.0208985 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0208237 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0206635 |
| NRG1 | neuregulin 1 | 0.0205375 |
| RPS27 | ribosomal protein S27 | 0.0202677 |
| RPL35A | ribosomal protein L35a | 0.0202035 |
| BICC1 | BicC family RNA binding protein 1 | 0.0201425 |
| RPL37A | ribosomal protein L37a | 0.0200038 |
| CUX1 | cut-like homeobox 1 | 0.0199724 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0196367 |
| TXNRD1 | thioredoxin reductase 1 | 0.0193746 |
| DST | dystonin | 0.0193237 |
| ZFHX3 | zinc finger homeobox 3 | 0.0192335 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0190599 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0187902 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0187253 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.018713 |
| RPS15 | ribosomal protein S15 | 0.0184579 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0184242 |
| DSTN | destrin (actin depolymerizing factor) | 0.0184149 |
| RPL38 | ribosomal protein L38 | 0.0182844 |
| TCIM | transcriptional and immune response regulator | 0.0182101 |
| LYST | lysosomal trafficking regulator | 0.0181787 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0181314 |
| BPTF | bromodomain PHD finger transcription factor | 0.018129 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.107987 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0996052 |
| FN1 | fibronectin 1 | -0.0882301 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.085631 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0771571 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0763333 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0681492 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0627333 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0617466 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0574757 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.055166 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0503569 |
| NDRG1 | N-myc downstream regulated 1 | -0.0496507 |
| SPAG9 | sperm associated antigen 9 | -0.0482109 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0474519 |
| RNF145 | ring finger protein 145 | -0.0469222 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0444294 |
| ASPH | aspartate beta-hydroxylase | -0.0443339 |
| PTMA | prothymosin, alpha | -0.0430091 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0428416 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0418951 |
| COPA | coatomer protein complex, subunit alpha | -0.0415675 |
| SEPTIN7 | septin 7 | -0.0411622 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0409707 |
| ZNF292 | zinc finger protein 292 | -0.0401755 |
| SUCO | SUN domain containing ossification factor | -0.0395645 |
| HELZ | helicase with zinc finger | -0.0392788 |
| NUP58 | nucleoporin 58 | -0.0384877 |
| RBM39 | RNA binding motif protein 39 | -0.0371149 |
| WDR45B | WD repeat domain 45B | -0.0367281 |
| FAM13A | family with sequence similarity 13, member A | -0.0364112 |
| WAC | WW domain containing adaptor with coiled-coil | -0.03618 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0360427 |
| TXNIP | thioredoxin interacting protein | -0.0356974 |
| OGA | O-GlcNAcase | -0.0346768 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0345534 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0338811 |
| TFG | TRK-fused gene | -0.033252 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0331758 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0327649 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327161 |
| PTK2 | protein tyrosine kinase 2 | -0.0320651 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0313346 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0310777 |
| RTN4 | reticulon 4 | -0.0307293 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0306399 |
| XPO1 | exportin 1 | -0.0301364 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0293822 |
| CANX | calnexin | -0.0292095 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0291017 |
| ANLN | anillin, actin binding protein | -0.0290315 |
| USP3 | ubiquitin specific peptidase 3 | -0.0289204 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0288262 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0284831 |
| EREG | epiregulin | -0.0282724 |
| TPD52 | tumor protein D52 | -0.0280204 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0279064 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0277513 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0275407 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0274685 |
| GOLGA4 | golgin A4 | -0.0273956 |
| RNF24 | ring finger protein 24 | -0.0273264 |
| FOSL1 | FOS-like antigen 1 | -0.0271511 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0270981 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0267688 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0258914 |
| TPM3 | tropomyosin 3 | -0.0258028 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0257228 |
| CDC73 | cell division cycle 73 | -0.0256862 |
| RLF | rearranged L-myc fusion | -0.0256854 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0254837 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0254811 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.025368 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0253582 |
| YBX1 | Y box binding protein 1 | -0.0252515 |
| CENPF | centromere protein F, 350/400kDa | -0.0252047 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0251977 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0249534 |
| SETD5 | SET domain containing 5 | -0.0248586 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0247667 |
| NEK7 | NIMA-related kinase 7 | -0.0246424 |
| CDC27 | cell division cycle 27 | -0.0244095 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0243156 |
| QKI | QKI, KH domain containing, RNA binding | -0.0239149 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0236464 |
| NOP58 | NOP58 ribonucleoprotein | -0.0233606 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0231608 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.023066 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0230453 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0229212 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.02282 |
| PELO | pelota homolog (Drosophila) | -0.0225796 |
| SMOX | spermine oxidase | -0.0219839 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0219776 |
| INSIG2 | insulin induced gene 2 | -0.021958 |
| TOP1 | topoisomerase (DNA) I | -0.021738 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0216845 |
| HMGA1 | high mobility group AT-hook 1 | -0.0216255 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0216227 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.021584 |
