Xerostomia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Dryness of the mouth due to salivary gland dysfunction. (Human Phenotype Ontology, HP_0000217)
External Link https://www.disgenet.org/browser/0/1/0/C0043352
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Genes

56 genes associated with the disease Xerostomia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AFG3L2 AFG3-like AAA ATPase 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA11 annexin A11
ATXN2 ataxin 2
B2M beta-2-microglobulin
C21ORF2 chromosome 21 open reading frame 2
C9ORF72 chromosome 9 open reading frame 72
CAV1 caveolin 1, caveolae protein, 22kDa
CCN2 cellular communication network factor 2
CCNF cyclin F
CCR6 chemokine (C-C motif) receptor 6
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10
CHMP2B charged multivesicular body protein 2B
CHRM3 cholinergic receptor, muscarinic 3
CLDN10 claudin 10
DAO D-amino-acid oxidase
DCTN1 dynactin 1
EDARADD EDAR-associated death domain
EPHA4 EPH receptor A4
ERBB4 erb-b2 receptor tyrosine kinase 4
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FIG4 FIG4 phosphoinositide 5-phosphatase
FUS FUS RNA binding protein
GLE1 GLE1 RNA export mediator
GLT8D1 glycosyltransferase 8 domain containing 1
GSN gelsolin
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IRF5 interferon regulatory factor 5
LBR lamin B receptor
MATR3 matrin 3
NEFH neurofilament, heavy polypeptide
NEK1 NIMA-related kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
OPTN optineurin
PFN1 profilin 1
PON1 paraoxonase 1
PON2 paraoxonase 2
PON3 paraoxonase 3
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRPH peripherin
SCN9A sodium channel, voltage gated, type IX alpha subunit
SOD1 superoxide dismutase 1, soluble
SQSTM1 sequestosome 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARDBP TAR DNA binding protein
TBK1 TANK-binding kinase 1
TP63 tumor protein p63
TREM2 triggering receptor expressed on myeloid cells 2
TUBB6 tubulin, beta 6 class V
UBQLN2 ubiquilin 2
UNC13A unc-13 homolog A (C. elegans)
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VCP valosin containing protein