| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the Y-27632-948 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACVR1B | activin A receptor, type IB |
| ALPK1 | alpha-kinase 1 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ART1 | ADP-ribosyltransferase 1 |
| ATG4B | autophagy related 4B, cysteine peptidase |
| BAX | BCL2-associated X protein |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDC25A | cell division cycle 25A |
| CDK13 | cyclin-dependent kinase 13 |
| CEP162 | centrosomal protein 162kDa |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DMTN | dematin actin binding protein |
| DTNA | dystrobrevin, alpha |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHB2 | EPH receptor B2 |
| EXOC7 | exocyst complex component 7 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAS7 | growth arrest-specific 7 |
| GK3P | glycerol kinase 3 pseudogene |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GSTM4 | glutathione S-transferase mu 4 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GYG2 | glycogenin 2 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HLA-G | major histocompatibility complex, class I, G |
| HOXA2 | homeobox A2 |
| IFT122 | intraflagellar transport 122 |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| LDB1 | LIM domain binding 1 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MBD1 | methyl-CpG binding domain protein 1 |
| MCC | mutated in colorectal cancers |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MYL5 | myosin, light chain 5, regulatory |
| NCOR2 | nuclear receptor corepressor 2 |
| NEB | nebulin |
| NEK11 | NIMA-related kinase 11 |
| NF1 | neurofibromin 1 |
| NPTX1 | neuronal pentraxin I |
| NRG1 | neuregulin 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PAPOLA | poly(A) polymerase alpha |
| PCNX | pecanex homolog (Drosophila) |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PEX5 | peroxisomal biogenesis factor 5 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| QKI | QKI, KH domain containing, RNA binding |
| RAB27B | RAB27B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RHOQ | ras homolog family member Q |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPS28 | ribosomal protein S28 |
| SCAF4 | SR-related CTD-associated factor 4 |
| SCARB1 | scavenger receptor class B, member 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFTPB | surfactant protein B |
| SHARPIN | SHANK-associated RH domain interactor |
| SYMPK | symplekin |
| TEAD3 | TEA domain family member 3 |
| TERT | telomerase reverse transcriptase |
| TGFB2 | transforming growth factor, beta 2 |
| THAP9 | THAP domain containing 9 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| ZNF224 | zinc finger protein 224 |
| ZNF329 | zinc finger protein 329 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACVR2A | activin A receptor, type IIA |
| AES | amino-terminal enhancer of split |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARMC6 | armadillo repeat containing 6 |
| ARRB1 | arrestin, beta 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL9 | B-cell CLL/lymphoma 9 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA11 | carbonic anhydrase XI |
| CASD1 | CAS1 domain containing 1 |
| CLSPN | claspin |
| CNPY3 | canopy FGF signaling regulator 3 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DMXL1 | Dmx-like 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DUSP8 | dual specificity phosphatase 8 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ECSIT | ECSIT signalling integrator |
| EHD3 | EH-domain containing 3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| F8 | coagulation factor VIII, procoagulant component |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HMG20A | high mobility group 20A |
| HS1BP3 | HCLS1 binding protein 3 |
| IRF2 | interferon regulatory factor 2 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KLC2 | kinesin light chain 2 |
| KRT86 | keratin 86, type II |
| MANSC1 | MANSC domain containing 1 |
| MAP7D3 | MAP7 domain containing 3 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MDM4 | MDM4, p53 regulator |
| METTL2B | methyltransferase like 2B |
| METTL8 | methyltransferase like 8 |
| MEX3C | mex-3 RNA binding family member C |
| MOSPD3 | motile sperm domain containing 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NCAM2 | neural cell adhesion molecule 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUBPL | nucleotide binding protein-like |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OSMR | oncostatin M receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PERP | PERP, TP53 apoptosis effector |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RRAGB | Ras-related GTP binding B |
| RWDD3 | RWD domain containing 3 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SMAD7 | SMAD family member 7 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNX16 | sorting nexin 16 |
| SP140L | SP140 nuclear body protein-like |
| SYNGR3 | synaptogyrin 3 |
| TMEM110 | transmembrane protein 110 |
| TMEM62 | transmembrane protein 62 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UROS | uroporphyrinogen III synthase |
| WDR91 | WD repeat domain 91 |
| YBX2 | Y box binding protein 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF365 | zinc finger protein 365 |
| ZNF432 | zinc finger protein 432 |
| ZNF510 | zinc finger protein 510 |
| ZNF552 | zinc finger protein 552 |
| ZNF574 | zinc finger protein 574 |
| ZNF623 | zinc finger protein 623 |
| ZNF665 | zinc finger protein 665 |
| ZNF778 | zinc finger protein 778 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
