| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Yes-associated protein 1|This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 10413) |
| External Link | https://ncbi.nlm.nih.gov/gene/10413 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the YAP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | 0.0170811 |
| KRT7 | keratin 7, type II | 0.0154137 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0121121 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0121038 |
| KRT19 | keratin 19, type I | 0.0120724 |
| IL1B | interleukin 1, beta | 0.0120282 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0109011 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0104221 |
| ANXA1 | annexin A1 | 0.0102996 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0101368 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0100406 |
| POSTN | periostin, osteoblast specific factor | 0.00978068 |
| TLR4 | toll-like receptor 4 | 0.00972876 |
| THBS2 | thrombospondin 2 | 0.00949781 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00942651 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00921392 |
| TPD52L1 | tumor protein D52-like 1 | 0.00883594 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00879604 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00828835 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00804832 |
| NRCAM | neuronal cell adhesion molecule | 0.00781126 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00763362 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00757781 |
| G0S2 | G0/G1 switch 2 | 0.00754145 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0073937 |
| BAD | BCL2-associated agonist of cell death | 0.00737934 |
| NRN1 | neuritin 1 | 0.00733547 |
| FOXG1 | forkhead box G1 | 0.00731795 |
| LUM | lumican | 0.00730326 |
| AK5 | adenylate kinase 5 | 0.00728703 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.00720115 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00714119 |
| CLDN7 | claudin 7 | 0.00710424 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00703736 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00702208 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00694804 |
| PCDH9 | protocadherin 9 | 0.00693787 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00692034 |
| PERP | PERP, TP53 apoptosis effector | 0.00688074 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00686252 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00685345 |
| TAGLN2 | transgelin 2 | 0.00684883 |
| ANO10 | anoctamin 10 | 0.0068353 |
| TSPO | translocator protein (18kDa) | 0.00680949 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00679144 |
| KLF6 | Kruppel-like factor 6 | 0.00676656 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0067552 |
| IRS2 | insulin receptor substrate 2 | 0.00674911 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00674713 |
| CSTA | cystatin A (stefin A) | 0.00669537 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00669474 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00664659 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00659592 |
| BMP7 | bone morphogenetic protein 7 | 0.00650761 |
| RND3 | Rho family GTPase 3 | 0.00650734 |
| GLOD4 | glyoxalase domain containing 4 | 0.00650441 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00647895 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00647001 |
| MME | membrane metallo-endopeptidase | 0.00645304 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00639548 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00635403 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00634413 |
| THEMIS2 | thymocyte selection associated family member 2 | 0.00633735 |
| TXN | thioredoxin | 0.00631528 |
| ZNF281 | zinc finger protein 281 | 0.00630083 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00629342 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0062775 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0062676 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00622769 |
| GPI | glucose-6-phosphate isomerase | 0.00620738 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0061923 |
| SIRPA | signal-regulatory protein alpha | 0.00615271 |
| ABHD6 | abhydrolase domain containing 6 | 0.00614962 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | 0.00613543 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00611372 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00611145 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00609755 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00609679 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00604507 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 0.0060079 |
| EDN3 | endothelin 3 | 0.0059969 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00599635 |
| S100A8 | S100 calcium binding protein A8 | 0.00598171 |
| FGF9 | fibroblast growth factor 9 | 0.00597658 |
| CTSB | cathepsin B | 0.00597026 |
| DSP | desmoplakin | 0.00596001 |
| DEFB1 | defensin, beta 1 | 0.0059234 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00591575 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.00587765 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.00587323 |
| MVP | major vault protein | 0.00584851 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) | 0.00581233 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00580945 |
| PSAP | prosaposin | 0.00580625 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00580025 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00579593 |
| EMX2 | empty spiracles homeobox 2 | 0.00578159 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00570057 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0056932 |
| APOL1 | apolipoprotein L, 1 | 0.00567478 |
| CA2 | carbonic anhydrase II | 0.00566869 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.00565729 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00563563 |
| FDX1 | ferredoxin 1 | 0.00562134 |
| CLCA4 | chloride channel accessory 4 | 0.00558386 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | 0.00557479 |
| CTSS | cathepsin S | 0.00557189 |
| LMBRD1 | LMBR1 domain containing 1 | 0.00557107 |
| MAOA | monoamine oxidase A | 0.00555279 |
| ZNF91 | zinc finger protein 91 | 0.00553827 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00553426 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00552457 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00551915 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00550773 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00549134 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00549124 |
| ZNF365 | zinc finger protein 365 | 0.00547081 |
| IL1R1 | interleukin 1 receptor, type I | 0.00546799 |
| CLIC4 | chloride intracellular channel 4 | 0.00546291 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00545629 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00545193 |
| FKBP2 | FK506 binding protein 2, 13kDa | 0.0054334 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00541499 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.005413 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00541294 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00539951 |
| TMEM100 | transmembrane protein 100 | 0.00538355 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00537651 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00537636 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00535874 |
| ASPH | aspartate beta-hydroxylase | 0.00535622 |
| CES1 | carboxylesterase 1 | 0.00535441 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | 0.00535414 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.00534402 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00534238 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | 0.00534106 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00532212 |
| HLA-B | major histocompatibility complex, class I, B | 0.00531916 |
| S100A11 | S100 calcium binding protein A11 | 0.00530621 |
| KRT8 | keratin 8, type II | 0.00530184 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00530161 |
| TLE5 | TLE family member 5, transcriptional modulator | 0.00527062 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00525227 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00525143 |
| PRDX3 | peroxiredoxin 3 | 0.00523144 |
| IFNGR1 | interferon gamma receptor 1 | 0.00522873 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00522745 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00520839 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00520631 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0051896 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00518868 |
| LTF | lactotransferrin | 0.00518795 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00514909 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00514448 |
| GSDMB | gasdermin B | 0.00512865 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00509964 |
| FAM3C | family with sequence similarity 3, member C | 0.0050983 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00509024 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00507789 |
| CFH | complement factor H | 0.00505188 |
| MFAP5 | microfibrillar associated protein 5 | 0.00503891 |
| VCAN | versican | 0.00503822 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00503396 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00502426 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00502419 |
| NCAN | neurocan | 0.00500568 |
| OSTF1 | osteoclast stimulating factor 1 | 0.00499385 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00498881 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.0049648 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 0.00495386 |
| CTSA | cathepsin A | 0.00491292 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00490626 |
| CLDN8 | claudin 8 | 0.00490337 |
| ITGB4 | integrin, beta 4 | 0.00490121 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00490116 |
| CDK14 | cyclin-dependent kinase 14 | 0.00489994 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00489903 |
| ELMO1 | engulfment and cell motility 1 | 0.00489896 |
| CD200 | CD200 molecule | 0.00487424 |
| DSTN | destrin (actin depolymerizing factor) | 0.00486947 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0048484 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00483089 |
| SV2B | synaptic vesicle glycoprotein 2B | 0.00482968 |
| GPX4 | glutathione peroxidase 4 | 0.00481871 |
| GPR137B | G protein-coupled receptor 137B | 0.00481444 |
| KRT23 | keratin 23, type I | 0.00480864 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0048034 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0048011 |
| DUSP4 | dual specificity phosphatase 4 | 0.00479721 |
| PSCA | prostate stem cell antigen | 0.00478806 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | 0.00478509 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00477436 |
| INHBA | inhibin, beta A | 0.0047706 |
| SELENOT | selenoprotein T | 0.0047591 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00475476 |
| VGLL4 | vestigial-like family member 4 | 0.00474839 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00474456 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00474105 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00472878 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00472247 |
| TRIM16 | tripartite motif containing 16 | 0.00472015 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00471951 |
| ERGIC3 | ERGIC and golgi 3 | 0.00471665 |
| HEBP2 | heme binding protein 2 | 0.00471374 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00470561 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 0.00469678 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00469111 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00467937 |
| RGS4 | regulator of G-protein signaling 4 | 0.00465856 |
| ADD3 | adducin 3 (gamma) | 0.00465574 |
| OPN3 | opsin 3 | 0.00464793 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00464631 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00463434 |
| PCBP2 | poly(rC) binding protein 2 | 0.00461794 |
| AGPS | alkylglycerone phosphate synthase | 0.00460948 |
| EMP1 | epithelial membrane protein 1 | 0.0046075 |
| PPIF | peptidylprolyl isomerase F | 0.00460127 |
| CHEK2 | checkpoint kinase 2 | 0.00459991 |
| ADORA2B | adenosine A2b receptor | 0.00459836 |
| TMEM176B | transmembrane protein 176B | 0.00459595 |
| TGFA | transforming growth factor, alpha | 0.00459334 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00458471 |
| VSNL1 | visinin-like 1 | 0.00458365 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00458206 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00458044 |
| TMEM59 | transmembrane protein 59 | 0.00457293 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00457006 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00456674 |
| LY96 | lymphocyte antigen 96 | 0.00456671 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.00455621 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00455297 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00454907 |
| KRT5 | keratin 5, type II | 0.00454533 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 0.00453166 |
| PRKCSH | protein kinase C substrate 80K-H | 0.00452265 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 | 0.00452232 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00449848 |
| ADM | adrenomedullin | 0.00449494 |
| CLIC5 | chloride intracellular channel 5 | 0.00449183 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.00448997 |
| FADS3 | fatty acid desaturase 3 | 0.00448916 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00448388 |
| JUNB | jun B proto-oncogene | 0.00447834 |
| COX5B | cytochrome c oxidase subunit Vb | 0.00447674 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00447659 |
| PIP | prolactin-induced protein | 0.00447289 |
| KLF9 | Kruppel-like factor 9 | 0.00446645 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.00446066 |
| OXTR | oxytocin receptor | 0.00446057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0133005 |
| GAL | galanin/GMAP prepropeptide | -0.0105765 |
| MATN2 | matrilin 2 | -0.00896995 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00880141 |
| PTK2 | protein tyrosine kinase 2 | -0.0087333 |
| DES | desmin | -0.00871618 |
| FERMT2 | fermitin family member 2 | -0.00839627 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00836857 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00829746 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00820009 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0081775 |
| KLHL23 | kelch-like family member 23 | -0.00802724 |
| NELL2 | NEL-like 2 (chicken) | -0.00795484 |
| NEFH | neurofilament, heavy polypeptide | -0.00788926 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00729624 |
| CPE | carboxypeptidase E | -0.00726961 |
| CHKB | choline kinase beta | -0.00724256 |
| ELN | elastin | -0.00723143 |
| SYNGR3 | synaptogyrin 3 | -0.00716672 |
| CRY1 | cryptochrome circadian clock 1 | -0.00715674 |
| DSG1 | desmoglein 1 | -0.0071288 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00712111 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00707461 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00703625 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00686783 |
| SPRR2B | small proline-rich protein 2B | -0.00686611 |
| COL2A1 | collagen, type II, alpha 1 | -0.00686023 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00685118 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00677045 |
| LOR | loricrin | -0.00675678 |
| FLNC | filamin C, gamma | -0.00675232 |
| TTN | titin | -0.0067113 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00669674 |
| HOPX | HOP homeobox | -0.00667331 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00662467 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00661971 |
| SIRT3 | sirtuin 3 | -0.00661299 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00648417 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00644666 |
| TNNC2 | troponin C type 2 (fast) | -0.00643559 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00642931 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00641326 |
| CKM | creatine kinase, muscle | -0.00634871 |
| PLK1 | polo-like kinase 1 | -0.00631532 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00630219 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00628325 |
| GPC3 | glypican 3 | -0.0062426 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -0.00620134 |
| APOA2 | apolipoprotein A-II | -0.00619712 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00617689 |
| MALL | mal, T-cell differentiation protein-like | -0.00616511 |
| RHOB | ras homolog family member B | -0.00613762 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00605016 |
| TEAD4 | TEA domain family member 4 | -0.00604121 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00603011 |
| CDC45 | cell division cycle 45 | -0.00601745 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00598002 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00589487 |
| AHSG | alpha-2-HS-glycoprotein | -0.00579368 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00578261 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0057731 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00576444 |
| SPAG1 | sperm associated antigen 1 | -0.00575496 |
| S100A7 | S100 calcium binding protein A7 | -0.00574982 |
| CCNB2 | cyclin B2 | -0.00574331 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00572872 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00572393 |
| AGR2 | anterior gradient 2 | -0.00572122 |
| SFTPD | surfactant protein D | -0.00572058 |
| FRZB | frizzled-related protein | -0.00566819 |
| FST | follistatin | -0.00565586 |
| NKG7 | natural killer cell granule protein 7 | -0.00565068 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00561802 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.00560985 |
| PRDX4 | peroxiredoxin 4 | -0.00560537 |
| KRT1 | keratin 1, type II | -0.00560243 |
| SNX10 | sorting nexin 10 | -0.00558964 |
| AFP | alpha-fetoprotein | -0.00554723 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.005542 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00551135 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00549362 |
| SUCO | SUN domain containing ossification factor | -0.00549115 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00548351 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00542885 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00540499 |
| SMTN | smoothelin | -0.00539137 |
| KLHL21 | kelch-like family member 21 | -0.00538154 |
| IDE | insulin-degrading enzyme | -0.00535522 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.00534629 |
| PEG3 | paternally expressed 3 | -0.00532474 |
| ESR1 | estrogen receptor 1 | -0.00530136 |
| ZNF586 | zinc finger protein 586 | -0.00526858 |
| ISOC1 | isochorismatase domain containing 1 | -0.00526615 |
| FSTL1 | follistatin-like 1 | -0.00523821 |
| MYBPC2 | myosin binding protein C, fast type | -0.00522702 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00518588 |
| KIAA0355 | KIAA0355 | -0.00518206 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00516742 |
| ENO3 | enolase 3 (beta, muscle) | -0.00516415 |
| KLHL41 | kelch-like family member 41 | -0.00511185 |
| DEFB4A | defensin, beta 4A | -0.00507925 |
| NXN | nucleoredoxin | -0.00506994 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00506113 |
| DSC1 | desmocollin 1 | -0.00505802 |
| NVL | nuclear VCP-like | -0.00505485 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00502222 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00499406 |
| ITK | IL2-inducible T-cell kinase | -0.00498153 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00496787 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0049571 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | -0.00493296 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00492323 |
| ITM2A | integral membrane protein 2A | -0.00491737 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00489916 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00488406 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00488154 |
| IVL | involucrin | -0.00487509 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00486807 |
| THBS4 | thrombospondin 4 | -0.00485598 |
| NKX2-1 | NK2 homeobox 1 | -0.00484709 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00484694 |
| GMPR | guanosine monophosphate reductase | -0.00484235 |
| MB | myoglobin | -0.00483356 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00482494 |
| PRMT3 | protein arginine methyltransferase 3 | -0.00482144 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00482041 |
| CTSW | cathepsin W | -0.0047982 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00478855 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.0047851 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -0.00478339 |
| C4BPA | complement component 4 binding protein, alpha | -0.0047833 |
| TNNT3 | troponin T type 3 (skeletal, fast) | -0.004774 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00476462 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00475543 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00474816 |
| C7 | complement component 7 | -0.00474393 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00473714 |
| SACS | sacsin molecular chaperone | -0.00472995 |
| POGLUT2 | protein O-glucosyltransferase 2 | -0.00472829 |
| BIN1 | bridging integrator 1 | -0.00472287 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00471697 |
| MRPL20 | mitochondrial ribosomal protein L20 | -0.00471057 |
| EPHB2 | EPH receptor B2 | -0.00470801 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00470675 |
| BARD1 | BRCA1 associated RING domain 1 | -0.00468415 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00464223 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00463959 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00461933 |
| NMU | neuromedin U | -0.00461746 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -0.00461605 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | -0.00461225 |
| WWC3 | WWC family member 3 | -0.00460306 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0045921 |
| NCKAP1 | NCK-associated protein 1 | -0.00457259 |
| KAZN | kazrin, periplakin interacting protein | -0.00457139 |
| CDCA3 | cell division cycle associated 3 | -0.00455552 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00454811 |
| TTR | transthyretin | -0.004535 |
| ADCY3 | adenylate cyclase 3 | -0.00453381 |
| CREBBP | CREB binding protein | -0.00453151 |
| SEPTIN10 | septin 10 | -0.00451957 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00451673 |
| EPHX3 | epoxide hydrolase 3 | -0.00451015 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00450351 |
| CFB | complement factor B | -0.00450246 |
| GCH1 | GTP cyclohydrolase 1 | -0.00449899 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00449619 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0044936 |
| CBR3 | carbonyl reductase 3 | -0.00448854 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | -0.00447644 |
| SORBS3 | sorbin and SH3 domain containing 3 | -0.00447353 |
| DYSF | dysferlin | -0.00446387 |
| SEPTIN7 | septin 7 | -0.00446226 |
| NSG1 | neuron specific gene family member 1 | -0.00445378 |
| DCHS1 | dachsous cadherin-related 1 | -0.00444719 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00444501 |
| GYG1 | glycogenin 1 | -0.00444422 |
| KIF20A | kinesin family member 20A | -0.00443691 |
| KIAA0125 | KIAA0125 | -0.00442534 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.00442514 |
| AIM2 | absent in melanoma 2 | -0.00442114 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | -0.00442048 |
| CA3 | carbonic anhydrase III | -0.00440762 |
| USP12P1 | ubiquitin specific peptidase 12 pseudogene 1 | -0.00439575 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00439342 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | -0.00439096 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | -0.00437937 |
| RASIP1 | Ras interacting protein 1 | -0.00437609 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -0.00437499 |
| NANOG | Nanog homeobox | -0.00436833 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00435906 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00435643 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00434608 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00433902 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | -0.00433416 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00433385 |
| SMS | spermine synthase | -0.00433322 |
| LCE2B | late cornified envelope 2B | -0.00433194 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00432711 |
| REEP1 | receptor accessory protein 1 | -0.0043271 |
| NINJ2 | ninjurin 2 | -0.00432624 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00431204 |
| CDCA4 | cell division cycle associated 4 | -0.00430921 |
| SPRR1A | small proline-rich protein 1A | -0.00430319 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0042991 |
| TNS1 | tensin 1 | -0.00429713 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.00429566 |
| WT1 | Wilms tumor 1 | -0.00429498 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00427258 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00426123 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00425126 |
| PLS3 | plastin 3 | -0.00424554 |
| SGMS1 | sphingomyelin synthase 1 | -0.00424515 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00422949 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00421112 |
| ARG1 | arginase 1 | -0.00418353 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00417922 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00417453 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.00417129 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00415575 |
| FAM46C | family with sequence similarity 46, member C | -0.0041457 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00414225 |
| KIF23 | kinesin family member 23 | -0.00414195 |
| MMP13 | matrix metallopeptidase 13 | -0.00414069 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -0.00413683 |
| SFN | stratifin | -0.00413147 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00412319 |
| OTUD4 | OTU deubiquitinase 4 | -0.00412247 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00411027 |
| TMEM131L | transmembrane 131 like | -0.00410851 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | -0.00410691 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00410659 |
| ACD | adrenocortical dysplasia homolog (mouse) | -0.00410041 |
| ARHGAP17 | Rho GTPase activating protein 17 | -0.0040903 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00408579 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -0.00407694 |
| RBPMS | RNA binding protein with multiple splicing | -0.00407467 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00406892 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -0.00406149 |
| ZNF266 | zinc finger protein 266 | -0.00406068 |
| DEK | DEK proto-oncogene | -0.00405833 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00405226 |
| USP48 | ubiquitin specific peptidase 48 | -0.00405029 |
| RASL12 | RAS-like, family 12 | -0.00404489 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00403269 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00402993 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00401717 |
| RET | ret proto-oncogene | -0.00401386 |
