YRDC Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description yrdC N(6)-threonylcarbamoyltransferase domain containing| (NCBI Entrez Gene Database, 79693)
Similar Terms
Downloads & Tools

Genes

284 genes differentially expressed following the YRDC gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
C4ORF54 chromosome 4 open reading frame 54 3.39596
MMP12 matrix metallopeptidase 12 3.39596
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.39596
RNF17 ring finger protein 17 3.39596
IGFBP7 insulin-like growth factor binding protein 7 3.39596
SFTPB surfactant protein B 3.39596
RTP3 receptor (chemosensory) transporter protein 3 3.39596
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 3.39596
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.39596
APOH apolipoprotein H (beta-2-glycoprotein I) 3.39596
RHOXF2 Rhox homeobox family, member 2 3.39596
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 3.39596
STAB1 stabilin 1 3.39596
GOLGA8J golgin A8 family, member J 3.39596
HCRTR1 hypocretin (orexin) receptor 1 3.39596
LY6L lymphocyte antigen 6 family member L 3.39596
ATP5MGL ATP synthase membrane subunit g like 3.39596
MCHR1 melanin-concentrating hormone receptor 1 3.39596
HTD2 hydroxyacyl-thioester dehydratase type 2 3.39596
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 3.39596
CCL5 chemokine (C-C motif) ligand 5 3.33436
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 3.33436
NEU4 sialidase 4 3.33436
HBZ hemoglobin, zeta 3.33436
LONRF3 LON peptidase N-terminal domain and ring finger 3 3.33436
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 3.33436
TTLL2 tubulin tyrosine ligase-like family member 2 3.33436
GFI1 growth factor independent 1 transcription repressor 3.33436
DIRAS2 DIRAS family, GTP-binding RAS-like 2 3.33436
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 3.33436
UMOD uromodulin 3.33436
OR2J3 olfactory receptor, family 2, subfamily J, member 3 3.33436
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 3.33436
MYO1G myosin IG 3.33436
DCST1 DC-STAMP domain containing 1 3.33436
MNX1 motor neuron and pancreas homeobox 1 3.33436
MRGPRX3 MAS-related GPR, member X3 3.33436
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 3.33436
CD33 CD33 molecule 3.33436
FXYD2 FXYD domain containing ion transport regulator 2 3.33436
DSPP dentin sialophosphoprotein 3.33436
SPDEF SAM pointed domain containing ETS transcription factor 3.33436
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 3.33436
PRSS21 protease, serine, 21 (testisin) 3.33436
FGF7 fibroblast growth factor 7 3.33436
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 3.33436
LHX6 LIM homeobox 6 3.33436
NMUR2 neuromedin U receptor 2 3.33436
OIT3 oncoprotein induced transcript 3 3.33436
C21ORF140 chromosome 21 open reading frame 140 3.33436
CPLX3 complexin 3 3.33436
CLEC2A C-type lectin domain family 2, member A 3.33436
OR52A5 olfactory receptor, family 52, subfamily A, member 5 3.33436
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 3.33436
EXOC3L4 exocyst complex component 3-like 4 3.33436
CCR3 chemokine (C-C motif) receptor 3 3.33436
LTK leukocyte receptor tyrosine kinase 3.33436
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 3.33436
WASL-DT WASL divergent transcript 3.33436
OR52E4 olfactory receptor, family 52, subfamily E, member 4 3.33436
TSPAN1 tetraspanin 1 3.33436
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.33436
TRIM31 tripartite motif containing 31 3.33436
LMNTD1 lamin tail domain containing 1 3.33436
CAPN9 calpain 9 3.33436
AVPR1A arginine vasopressin receptor 1A 3.33436
CFAP157 cilia and flagella associated protein 157 3.33436
H2BC3 H2B clustered histone 3 3.33436
GLYATL1B glycine-N-acyltransferase like 1B 3.33436
MINDY4B MINDY family member 4B 3.33436
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 3.33436
SLC45A2 solute carrier family 45, member 2 3.33436
GDF10 growth differentiation factor 10 3.33436
NPPC natriuretic peptide C 3.33436
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.33436
ZNF503 zinc finger protein 503 3.33436
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 3.33436
NAPSA napsin A aspartic peptidase 3.33436
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 3.33436
FAM90A26 family with sequence similarity 90, member A26, pseudogene 3.33436
FAM187B family with sequence similarity 187, member B 3.33436
TMPRSS11F transmembrane protease, serine 11F 3.33436
TPBGL trophoblast glycoprotein-like 3.33436
GPR3 G protein-coupled receptor 3 3.33436
CD300E CD300e molecule 3.33436
ACTRT1 actin-related protein T1 3.33436
RAB44 RAB44, member RAS oncogene family 3.33436
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 3.33436
CATSPER3 cation channel, sperm associated 3 3.33436
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.33436
ZNF593OS ZNF593 opposite strand 3.33436
EPHA10 EPH receptor A10 3.33436
APOC2 apolipoprotein C-II 3.33436
F2RL2 coagulation factor II (thrombin) receptor-like 2 3.33436
HOXD1 homeobox D1 3.33436
CAMK2B calcium/calmodulin-dependent protein kinase II beta 3.33436
KLF2 Kruppel-like factor 2 3.33436
SH2D1A SH2 domain containing 1A 3.33436
CDHR5 cadherin-related family member 5 3.33436
CDH22 cadherin 22, type 2 3.33436
DEFB135 defensin, beta 135 3.33436
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.33436
MAB21L2 mab-21-like 2 (C. elegans) 3.33436
BTNL2 butyrophilin-like 2 3.33436
GP2 glycoprotein 2 (zymogen granule membrane) 3.33436
HAMP hepcidin antimicrobial peptide 3.33436
CLIC3 chloride intracellular channel 3 3.33436
HOXA7 homeobox A7 3.33436
VAV1 vav 1 guanine nucleotide exchange factor 3.33436
POU2AF1 POU class 2 associating factor 1 3.33436
FSHR follicle stimulating hormone receptor 3.33436
PRR35 proline rich 35 3.33436
SIRPG signal-regulatory protein gamma 3.33436
TEX12 testis expressed 12 3.33436
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3.33436
SIGLEC11 sialic acid binding Ig-like lectin 11 3.33436
CDH17 cadherin 17, LI cadherin (liver-intestine) 3.33436
PCDHA13 protocadherin alpha 13 3.33436
KLK11 kallikrein-related peptidase 11 3.33436
C8ORF89 chromosome 8 open reading frame 89 3.33436
SIAH3 siah E3 ubiquitin protein ligase family member 3 3.33436
COL17A1 collagen, type XVII, alpha 1 3.33436
TEKT2 tektin 2 (testicular) 3.33436
IL19 interleukin 19 3.33436
C2CD4B C2 calcium-dependent domain containing 4B 3.33436
BRD1 bromodomain containing 1 3.33436
IL17REL interleukin 17 receptor E-like 3.33436
CALML6 calmodulin-like 6 3.33436
POU3F2 POU class 3 homeobox 2 3.33436
VTCN1 V-set domain containing T cell activation inhibitor 1 3.33436
PXT1 peroxisomal, testis specific 1 3.33436
CHRM1 cholinergic receptor, muscarinic 1 3.33436
CLCA1 chloride channel accessory 1 3.33436
GRAPL GRB2-related adaptor protein-like 3.33436
LRRC31 leucine rich repeat containing 31 3.33436
IFITM10 interferon induced transmembrane protein 10 3.33436
RP1 retinitis pigmentosa 1 (autosomal dominant) 3.33436
OR51I2 olfactory receptor, family 51, subfamily I, member 2 3.33436
UNC5B unc-5 homolog B (C. elegans) 3.33436
CHRDL2 chordin-like 2 3.33436
POPDC2 popeye domain containing 2 3.33436
MKRN3 makorin ring finger protein 3 3.33436
TRPM8 transient receptor potential cation channel, subfamily M, member 8 3.33436
TOPAZ1 testis and ovary specific PAZ domain containing 1 3.33436
PLSCR5 phospholipid scramblase family, member 5 3.33436
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.33436
MYADML2 myeloid-associated differentiation marker-like 2 3.33436
CCL27 chemokine (C-C motif) ligand 27 3.33436
ESPNL espin-like 3.33436
KRT3 keratin 3, type II 3.33436
PCDHAC1 protocadherin alpha subfamily C, 1 3.33436
WNT2 wingless-type MMTV integration site family member 2 3.33436
PRSS54 protease, serine, 54 3.33436
ADAM18 ADAM metallopeptidase domain 18 3.33436
TIGIT T cell immunoreceptor with Ig and ITIM domains 3.33436
KLHL35 kelch-like family member 35 3.23812
GPR183 G protein-coupled receptor 183 3.23812
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 3.07469
OPRM1 opioid receptor, mu 1 2.97257
SPDYE2B speedy/RINGO cell cycle regulator family member E2B 2.92346
FKBP6 FK506 binding protein 6, 36kDa 2.85151
CEP85 centrosomal protein 85kDa 2.84953
ODC1 ornithine decarboxylase 1 2.79456
CRTAC1 cartilage acidic protein 1 2.77778
TCEAL5 transcription elongation factor A (SII)-like 5 2.74904
VASP vasodilator-stimulated phosphoprotein 2.566
GSTM2 glutathione S-transferase mu 2 (muscle) 2.55372
SLC25A27 solute carrier family 25, member 27 2.5161
OR2A14 olfactory receptor, family 2, subfamily A, member 14 2.48304
RYR2 ryanodine receptor 2 (cardiac) 2.47665
LAMA5 laminin, alpha 5 2.45837
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.45048
FAM171A2 family with sequence similarity 171, member A2 2.4314
TTC13 tetratricopeptide repeat domain 13 2.33402
SIRT1 sirtuin 1 2.32573
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.28943
SGPP2 sphingosine-1-phosphate phosphatase 2 2.28358
RPL38 ribosomal protein L38 2.22449
THAP6 THAP domain containing 6 2.2063
SRBD1 S1 RNA binding domain 1 2.19428
NEFH neurofilament, heavy polypeptide 2.18722
BTK Bruton agammaglobulinemia tyrosine kinase 2.18668
PHACTR2 phosphatase and actin regulator 2 2.17076
TRIM46 tripartite motif containing 46 2.1678
ZNF528 zinc finger protein 528 2.1678
ACOT13 acyl-CoA thioesterase 13 2.1678
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 2.16614
APOLTP apolipoprotein lipid transfer particle homolog 2.16614
AMBP alpha-1-microglobulin/bikunin precursor 2.16606
ZNF513 zinc finger protein 513 2.1613
SNUPN snurportin 1 2.14448
TSSK3 testis-specific serine kinase 3 2.13076
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 2.13076
NOP53 NOP53 ribosome biogenesis factor 2.1102
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 2.10956
AEN apoptosis enhancing nuclease 2.08102
CCND2 cyclin D2 2.06382
RAB3IP RAB3A interacting protein 2.05317
MRPS18B mitochondrial ribosomal protein S18B 2.04945
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 2.04899
IFI27 interferon, alpha-inducible protein 27 2.04899
IRGQ immunity-related GTPase family, Q 2.02364
BOD1L1 biorientation of chromosomes in cell division 1-like 1 2.02364
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 2.00274

decreased expression

Symbol Name Standardized Value
CIROZ ciliated left-right organizer protein containing ZP-N domains -3.39596
IRF4 interferon regulatory factor 4 -3.39596
CCDC159 coiled-coil domain containing 159 -3.39596
SPMAP2L sperm microtubule associated protein 2 like -3.39596
GGACT gamma-glutamylamine cyclotransferase -3.39596
EGFL6 EGF-like-domain, multiple 6 -3.39596
TRPC5OS TRPC5 opposite strand -3.33436
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -3.33436
RPL19 ribosomal protein L19 -3.33436
RCSD1 RCSD domain containing 1 -3.33436
NR1I2 nuclear receptor subfamily 1, group I, member 2 -3.33436
CCR6 chemokine (C-C motif) receptor 6 -3.33436
RUFY4 RUN and FYVE domain containing 4 -3.33436
PSORS1C1 psoriasis susceptibility 1 candidate 1 -3.33436
PLK5 polo-like kinase 5 -3.33436
OR6B1 olfactory receptor, family 6, subfamily B, member 1 -3.33436
NFE2 nuclear factor, erythroid 2 -3.33436
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) -3.33436
GLT6D1 glycosyltransferase 6 domain containing 1 -3.33436
MR1 major histocompatibility complex, class I-related -3.33436
CST1 cystatin SN -3.33436
TMEM269 transmembrane protein 269 -3.33436
PRH2 proline-rich protein HaeIII subfamily 2 -3.33436
NTN5 netrin 5 -3.33436
TAFA3 TAFA chemokine like family member 3 -3.33436
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -3.33436
LOC122539214 Zinc finger protein LOC122539214 -3.33436
GATA5 GATA binding protein 5 -3.33436
SMTNL1 smoothelin-like 1 -3.33436
PLIN4 perilipin 4 -3.32715
GUK1 guanylate kinase 1 -2.98349
KIAA1614 KIAA1614 -2.95996
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -2.86815
TRMO tRNA methyltransferase O -2.85151
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type -2.85151
DCPS decapping enzyme, scavenger -2.82712
RPS18 ribosomal protein S18 -2.77066
TAFA5 TAFA chemokine like family member 5 -2.63511
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -2.61041
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -2.54978
RPL29 ribosomal protein L29 -2.54978
ZNF581 zinc finger protein 581 -2.53602
SLC46A1 solute carrier family 46 (folate transporter), member 1 -2.49512
MAPK7 mitogen-activated protein kinase 7 -2.41478
GRK6 G protein-coupled receptor kinase 6 -2.39785
ZNF557 zinc finger protein 557 -2.39785
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -2.39785
GSG1 germ cell associated 1 -2.39785
EPOR erythropoietin receptor -2.39785
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -2.36823
CNTD1 cyclin N-terminal domain containing 1 -2.34611
IFT70B intraflagellar transport 70B -2.34611
INHA inhibin, alpha -2.34611
TMEM236 transmembrane protein 236 -2.34611
BAIAP3 BAI1-associated protein 3 -2.34611
NKAP NFKB activating protein -2.28361
CYTH1 cytohesin 1 -2.22994
SERTAD4 SERTA domain containing 4 -2.2063
TMEM243 transmembrane protein 243, mitochondrial -2.19079
LPAR4 lysophosphatidic acid receptor 4 -2.1678
LCA5L Leber congenital amaurosis 5-like -2.1678
ATG3 autophagy related 3 -2.1678
JMJD8 jumonji domain containing 8 -2.15426
KXD1 KxDL motif containing 1 -2.14302
DNAAF2 dynein, axonemal, assembly factor 2 -2.13076
CFD complement factor D (adipsin) -2.13076
PSD3 pleckstrin and Sec7 domain containing 3 -2.12004
ZNF138 zinc finger protein 138 -2.09486
CECR2 cat eye syndrome chromosome region, candidate 2 -2.08386
ITSN1 intersectin 1 (SH3 domain protein) -2.08029
EDNRB endothelin receptor type B -2.0737
RAB3A RAB3A, member RAS oncogene family -2.06382
GLG1 golgi glycoprotein 1 -2.06382
ICE1 interactor of little elongation complex ELL subunit 1 -2.04771
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.04376
ADPRHL1 ADP-ribosylhydrolase like 1 -2.03546
RCOR2 REST corepressor 2 -2.03147
CFAP20 cilia and flagella associated protein 20 -2.02837
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.0251
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.00155