YWHAQ Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta|This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10971)
External Link http://www.ncbi.nlm.nih.gov/gene/10971
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Genes

168 interacting proteins for hub protein YWHAQ from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM22 ADAM metallopeptidase domain 22
AR androgen receptor
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCR breakpoint cluster region
BRAF B-Raf proto-oncogene, serine/threonine kinase
CABIN1 calcineurin binding protein 1
CALML5 calmodulin-like 5
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAPN3 calpain 3, (p94)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBWD2 COBW domain containing 2
CCAR1 cell division cycle and apoptosis regulator 1
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDK11B cyclin-dependent kinase 11B
CDK14 cyclin-dependent kinase 14
CDK16 cyclin-dependent kinase 16
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRTC2 CREB regulated transcription coactivator 2
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK1G1 casein kinase 1, gamma 1
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAPK1 death-associated protein kinase 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND4A DENN/MADD domain containing 4A
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DISC1 disrupted in schizophrenia 1
E2F1 E2F transcription factor 1
EDC3 enhancer of mRNA decapping 3
EGFR epidermal growth factor receptor
EIF4A3 eukaryotic translation initiation factor 4A3
EMD emerin
EML3 echinoderm microtubule associated protein like 3
EPB41 erythrocyte membrane protein band 4.1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAM83G family with sequence similarity 83, member G
FGR FGR proto-oncogene, Src family tyrosine kinase
FSHR follicle stimulating hormone receptor
FXYD1 FXYD domain containing ion transport regulator 1
GABARAP GABA(A) receptor-associated protein
HAX1 HCLS1 associated protein X-1
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDLBP high density lipoprotein binding protein
HIST2H3C histone cluster 2, H3c
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
ING1 inhibitor of growth family, member 1
IRS2 insulin receptor substrate 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB4 integrin, beta 4
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNK9 potassium channel, two pore domain subfamily K, member 9
KIAA0930 KIAA0930
KIF23 kinesin family member 23
KIF5B kinesin family member 5B
KIF5C kinesin family member 5C
KLC2 kinesin light chain 2
KLC3 kinesin light chain 3
KLC4 kinesin light chain 4
KRT1 keratin 1, type II
KRT18 keratin 18, type I
KRT9 keratin 9, type I
KSR1 kinase suppressor of ras 1
LARP1 La ribonucleoprotein domain family, member 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
LYST lysosomal trafficking regulator
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED1 mediator complex subunit 1
MEF2D myocyte enhancer factor 2D
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MPRIP myosin phosphatase Rho interacting protein
MST1R macrophage stimulating 1 receptor
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA1 nuclear receptor coactivator 1
NCOA3 nuclear receptor coactivator 3
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NRIP1 nuclear receptor interacting protein 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PANK2 pantothenate kinase 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PNKP polynucleotide kinase 3'-phosphatase
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRMT5 protein arginine methyltransferase 5
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAI14 retinoic acid induced 14
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS3 regulator of G-protein signaling 3
RGS7 regulator of G-protein signaling 7
RPL21 ribosomal protein L21
SAMD4B sterile alpha motif domain containing 4B
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SFN stratifin
SH3BP2 SH3-domain binding protein 2
SH3BP4 SH3-domain binding protein 4
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SMAD9 SMAD family member 9
SPIRE1 spire-type actin nucleation factor 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF10 serine/arginine-rich splicing factor 10
SRSF3 serine/arginine-rich splicing factor 3
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TERT telomerase reverse transcriptase
TH tyrosine hydroxylase
THRA thyroid hormone receptor, alpha
TJP2 tight junction protein 2
TPR translocated promoter region, nuclear basket protein
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UNC79 unc-79 homolog (C. elegans)
USP8 ubiquitin specific peptidase 8
WDR77 WD repeat domain 77
WEE1 WEE1 G2 checkpoint kinase
YAP1 Yes-associated protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta