| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | zeta-chain (TCR) associated protein kinase 70kDa|This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7535) |
| External Link | https://ncbi.nlm.nih.gov/gene/7535 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the ZAP70 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKCA | protein kinase C, alpha | 0.0164002 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.0134964 |
| KIF14 | kinesin family member 14 | 0.0125194 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.0117168 |
| GPATCH8 | G patch domain containing 8 | 0.0111289 |
| LTA4H | leukotriene A4 hydrolase | 0.010772 |
| NPR3 | natriuretic peptide receptor 3 | 0.0106812 |
| CD200 | CD200 molecule | 0.0105798 |
| DAPK1 | death-associated protein kinase 1 | 0.0105345 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0105065 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0103535 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.010245 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0100434 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.010013 |
| SRP72 | signal recognition particle 72kDa | 0.00997334 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00985346 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00981915 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00974739 |
| PITX3 | paired-like homeodomain 3 | 0.00966112 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00963234 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 0.00937402 |
| CCN2 | cellular communication network factor 2 | 0.00920921 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00918793 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00917333 |
| SET | SET nuclear proto-oncogene | 0.00916654 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00911229 |
| MMP12 | matrix metallopeptidase 12 | 0.00910231 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00907406 |
| PODXL | podocalyxin-like | 0.00903539 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00896345 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 | 0.00892346 |
| CD1E | CD1e molecule | 0.00891498 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00891127 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00883111 |
| USP6NL | USP6 N-terminal like | 0.00875871 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00874614 |
| PRKD1 | protein kinase D1 | 0.00870957 |
| USP34 | ubiquitin specific peptidase 34 | 0.00866416 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00859739 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00856832 |
| NELL1 | NEL-like 1 (chicken) | 0.00855682 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00850255 |
| GPM6A | glycoprotein M6A | 0.00848518 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00847659 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00845115 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0084444 |
| RPL10 | ribosomal protein L10 | 0.00842024 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00840645 |
| AZIN1 | antizyme inhibitor 1 | 0.00837922 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00835754 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00835483 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00835197 |
| MCOLN1 | mucolipin 1 | 0.00832135 |
| KIF23 | kinesin family member 23 | 0.00831683 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00822699 |
| SATB2 | SATB homeobox 2 | 0.00817695 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00817201 |
| MDFIC | MyoD family inhibitor domain containing | 0.00815871 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.00812319 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00812001 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00810987 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00808375 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00804826 |
| MYO5C | myosin VC | 0.00804229 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00804102 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.00800395 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.00795391 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00795017 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00788178 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00782146 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00778147 |
| RHOA | ras homolog family member A | 0.00775921 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00774407 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00773632 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00773363 |
| YLPM1 | YLP motif containing 1 | 0.00772077 |
| MKI67 | marker of proliferation Ki-67 | 0.00770667 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00766944 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00766208 |
| ADORA2B | adenosine A2b receptor | 0.00761952 |
| CENPE | centromere protein E, 312kDa | 0.00757875 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.00756151 |
| RAI14 | retinoic acid induced 14 | 0.00756142 |
| GPHN | gephyrin | 0.00755827 |
| EXOC5 | exocyst complex component 5 | 0.00755672 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00754978 |
| NKX2-1 | NK2 homeobox 1 | 0.00751895 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.00749624 |
| NCK1 | NCK adaptor protein 1 | 0.00747952 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00746722 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00742526 |
| LRRC59 | leucine rich repeat containing 59 | 0.0074129 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00738407 |
| LMNB1 | lamin B1 | 0.00738121 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00728556 |
| F2R | coagulation factor II (thrombin) receptor | 0.00728497 |
| CAPN7 | calpain 7 | 0.00727299 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | 0.00724891 |
| CD1D | CD1d molecule | 0.00724285 |
| DMXL1 | Dmx-like 1 | 0.00722357 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00718998 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00718808 |
| GSAP | gamma-secretase activating protein | 0.00715473 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0071497 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00714796 |
| MATR3 | matrin 3 | 0.00714706 |
| CYP7A1 | cytochrome P450, family 7, subfamily A, polypeptide 1 | 0.00713951 |
| XPO7 | exportin 7 | 0.00713937 |
| NUP205 | nucleoporin 205kDa | 0.00713854 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00712351 |
| CD14 | CD14 molecule | 0.00711298 |
| SMAD4 | SMAD family member 4 | 0.00709726 |
| PTCH1 | patched 1 | 0.00708217 |
| FAM169A | family with sequence similarity 169, member A | 0.00707479 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.00707108 |
| HLTF | helicase-like transcription factor | 0.00705736 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00705194 |
| ACLY | ATP citrate lyase | 0.00704135 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00702416 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00701728 |
| COBL | cordon-bleu WH2 repeat protein | 0.00700401 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00696983 |
| FOXJ3 | forkhead box J3 | 0.00696087 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.00695927 |
| KAT7 | K(lysine) acetyltransferase 7 | 0.0069464 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00694113 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00693952 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.00693832 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00692784 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 0.00690394 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00689415 |
| TOX3 | TOX high mobility group box family member 3 | 0.00688784 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0068725 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 0.00687 |
| IRS2 | insulin receptor substrate 2 | 0.00680605 |
| PLCL2 | phospholipase C-like 2 | 0.00677436 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00676363 |
| HOXA5 | homeobox A5 | 0.00675042 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00673783 |
| NNT | nicotinamide nucleotide transhydrogenase | 0.00673089 |
| CHEK1 | checkpoint kinase 1 | 0.00672643 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00671382 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00671221 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00668991 |
| CEP55 | centrosomal protein 55kDa | 0.00668677 |
| PITRM1 | pitrilysin metallopeptidase 1 | 0.00665061 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00664629 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00663949 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00663747 |
| STAG1 | stromal antigen 1 | 0.00663713 |
| H1-10 | H1.10 linker histone | 0.00663033 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) | 0.00662262 |
| ZNF207 | zinc finger protein 207 | 0.00661898 |
| MED14 | mediator complex subunit 14 | 0.00660652 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00659971 |
| PFKP | phosphofructokinase, platelet | 0.00659604 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00657842 |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | 0.00655027 |
| MEX3D | mex-3 RNA binding family member D | 0.0065486 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00652749 |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 | 0.00651277 |
| PLK1 | polo-like kinase 1 | 0.00651204 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0065021 |
| FZD3 | frizzled class receptor 3 | 0.00649649 |
| IPO5 | importin 5 | 0.00648647 |
| ASRGL1 | asparaginase like 1 | 0.00648213 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.00647444 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00646979 |
| TNPO1 | transportin 1 | 0.0064661 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.00646605 |
| NLGN4X | neuroligin 4, X-linked | 0.00646032 |
| DERL1 | derlin 1 | 0.0064485 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.00644542 |
| RBM25 | RNA binding motif protein 25 | 0.00643565 |
| TLR4 | toll-like receptor 4 | 0.00643185 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00641157 |
| TTC37 | tetratricopeptide repeat domain 37 | 0.00640489 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00640329 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00640243 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00638252 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00638246 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.00637665 |
| DMXL2 | Dmx-like 2 | 0.00637151 |
| DOCK10 | dedicator of cytokinesis 10 | 0.00635511 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0063494 |
| CCNA2 | cyclin A2 | 0.00634831 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00633854 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00633576 |
| UBXN7 | UBX domain protein 7 | 0.00633209 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00631272 |
| KIF11 | kinesin family member 11 | 0.00630999 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | 0.00630449 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00629788 |
| NUP160 | nucleoporin 160kDa | 0.00628689 |
| HIP1 | huntingtin interacting protein 1 | 0.00628008 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.00627931 |
| C9ORF40 | chromosome 9 open reading frame 40 | 0.006264 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.00626346 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.00625812 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00624567 |
| ZNF107 | zinc finger protein 107 | 0.00624433 |
| PLIN3 | perilipin 3 | 0.00623838 |
| BMP6 | bone morphogenetic protein 6 | 0.00623295 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00622423 |
| FGF2 | fibroblast growth factor 2 (basic) | 0.00622254 |
| MCM10 | minichromosome maintenance complex component 10 | 0.00621156 |
| ABHD17B | abhydrolase domain containing 17B | 0.00620999 |
| THAP9-AS1 | THAP9 antisense RNA 1 | 0.00620283 |
| GPR88 | G protein-coupled receptor 88 | 0.00618576 |
| LIMD1 | LIM domains containing 1 | 0.00617213 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00616932 |
| CPM | carboxypeptidase M | 0.00613758 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00612165 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.00609638 |
| RFX7 | regulatory factor X, 7 | 0.00609451 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.00608577 |
| ATR | ATR serine/threonine kinase | 0.00608303 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 0.00608245 |
| SNX1 | sorting nexin 1 | 0.00606348 |
| LAMA4 | laminin, alpha 4 | 0.00605933 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00604516 |
| MRPL36 | mitochondrial ribosomal protein L36 | 0.00603034 |
| PSAP | prosaposin | 0.00602651 |
| ATM | ATM serine/threonine kinase | 0.00599882 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.00598317 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0059828 |
| RNFT2 | ring finger protein, transmembrane 2 | 0.00597269 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00597064 |
| PRPF31 | pre-mRNA processing factor 31 | 0.00596819 |
| KLF3-AS1 | KLF3 antisense RNA 1 | 0.00595485 |
| RPGRIP1L | RPGRIP1-like | 0.00595011 |
| RBM8A | RNA binding motif protein 8A | 0.00594909 |
| SNX10 | sorting nexin 10 | 0.00594379 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.00593191 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00592439 |
| CEP70 | centrosomal protein 70kDa | 0.00591905 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.00591255 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00591163 |
| RDX | radixin | 0.00590956 |
| RASA4 | RAS p21 protein activator 4 | 0.00590823 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.00590107 |
| NFYA | nuclear transcription factor Y, alpha | 0.00589534 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00589134 |
| COPA | coatomer protein complex, subunit alpha | 0.00588318 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00587447 |
| RCAN1 | regulator of calcineurin 1 | 0.00586786 |
| MANEA | mannosidase, endo-alpha | 0.0058666 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.0058657 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00585559 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00585553 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0221765 |
| MT1E | metallothionein 1E | -0.0183495 |
| MT1F | metallothionein 1F | -0.0176426 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0175734 |
| CFB | complement factor B | -0.017315 |
| MT1G | metallothionein 1G | -0.0166578 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0150022 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0147399 |
| MT1H | metallothionein 1H | -0.013233 |
| MT1X | metallothionein 1X | -0.0131442 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0127483 |
| PCNA | proliferating cell nuclear antigen | -0.0125947 |
| RTN2 | reticulon 2 | -0.0125181 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0125041 |
| KRT23 | keratin 23, type I | -0.0118981 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.0117981 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0117853 |
| METTL7A | methyltransferase like 7A | -0.0115806 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0115623 |
| KRT5 | keratin 5, type II | -0.0115429 |
| PYCARD | PYD and CARD domain containing | -0.0114984 |
| TUBA4A | tubulin, alpha 4a | -0.0112236 |
| C3 | complement component 3 | -0.0111327 |
| CFH | complement factor H | -0.0111124 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0110949 |
| ASS1 | argininosuccinate synthase 1 | -0.0110385 |
| FST | follistatin | -0.0109096 |
| RPS27L | ribosomal protein S27-like | -0.010875 |
| S100A11 | S100 calcium binding protein A11 | -0.0108106 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.010794 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0105821 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0102848 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.010258 |
| LRRC17 | leucine rich repeat containing 17 | -0.0102364 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.0102056 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0101072 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.0100072 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00991617 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00990709 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00986663 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00970625 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00967263 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00964182 |
| PLIN2 | perilipin 2 | -0.00952473 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00944258 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00934497 |
| CD58 | CD58 molecule | -0.00933306 |
| CTSH | cathepsin H | -0.00928324 |
| IRF7 | interferon regulatory factor 7 | -0.00927908 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00921175 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00919938 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00915582 |
| LCN2 | lipocalin 2 | -0.00914895 |
| KRT17 | keratin 17, type I | -0.00904183 |
| TMEM176A | transmembrane protein 176A | -0.00895907 |
| RGS16 | regulator of G-protein signaling 16 | -0.00891486 |
| MINK1 | misshapen-like kinase 1 | -0.0089117 |
| PTN | pleiotrophin | -0.00890045 |
| ABAT | 4-aminobutyrate aminotransferase | -0.0088947 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00887435 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00886591 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00883832 |
| NNMT | nicotinamide N-methyltransferase | -0.00883046 |
| CLU | clusterin | -0.00881131 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00880957 |
| PXDC1 | PX domain containing 1 | -0.00879923 |
| S100A2 | S100 calcium binding protein A2 | -0.00878569 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00878033 |
| PFDN4 | prefoldin subunit 4 | -0.00868257 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.0086411 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00856887 |
| APOB | apolipoprotein B | -0.00856852 |
| CHN2 | chimerin 2 | -0.00855502 |
| LUM | lumican | -0.0085258 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00850623 |
| MRPL57 | mitochondrial ribosomal protein L57 | -0.00850085 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00843172 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00835726 |
| MRPL40 | mitochondrial ribosomal protein L40 | -0.00829913 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.0082907 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00829045 |
| SNAI2 | snail family zinc finger 2 | -0.00825255 |
| COX5B | cytochrome c oxidase subunit Vb | -0.00824478 |
| ELN | elastin | -0.00816784 |
| PEG10 | paternally expressed 10 | -0.00815941 |
| SNAP29 | synaptosomal-associated protein, 29kDa | -0.00811632 |
| AGRN | agrin | -0.00811209 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00811109 |
| MGP | matrix Gla protein | -0.00810218 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0080608 |
| LDB3 | LIM domain binding 3 | -0.00804214 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00800634 |
| MB | myoglobin | -0.00797664 |
| MT1M | metallothionein 1M | -0.00793884 |
| STAB1 | stabilin 1 | -0.00792791 |
| AMH | anti-Mullerian hormone | -0.00791924 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00788015 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.0078685 |
| KRT6B | keratin 6B, type II | -0.00786449 |
| COMT | catechol-O-methyltransferase | -0.00778651 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00777942 |
| C2 | complement component 2 | -0.0077787 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00776872 |
| DES | desmin | -0.00776807 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00771132 |
| NIT1 | nitrilase 1 | -0.00770543 |
| UROD | uroporphyrinogen decarboxylase | -0.00769413 |
| IFI35 | interferon-induced protein 35 | -0.00766831 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00766178 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00765559 |
| CADM1 | cell adhesion molecule 1 | -0.00764427 |
| MIR22HG | MIR22 host gene | -0.00764362 |
| ENO3 | enolase 3 (beta, muscle) | -0.00761112 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.0075851 |
| CRYAB | crystallin, alpha B | -0.00755172 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0075419 |
| PANK2 | pantothenate kinase 2 | -0.00752915 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00751528 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00751098 |
| METTL5 | methyltransferase like 5 | -0.0074988 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0074878 |
| PPL | periplakin | -0.00743954 |
| CENPU | centromere protein U | -0.00742938 |
| MT2A | metallothionein 2A | -0.00737992 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00737907 |
| DUSP3 | dual specificity phosphatase 3 | -0.00732691 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00727606 |
| EMID1 | EMI domain containing 1 | -0.00727435 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0072677 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00726698 |
| SCAND1 | SCAN domain containing 1 | -0.00726563 |
| ZNF593 | zinc finger protein 593 | -0.00726471 |
| TYMS | thymidylate synthetase | -0.00725564 |
| PLVAP | plasmalemma vesicle associated protein | -0.00723355 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00722616 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00722598 |
| ATOX1 | antioxidant 1 copper chaperone | -0.00722407 |
| FILIP1L | filamin A interacting protein 1-like | -0.00722368 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) | -0.00721237 |
| GLRX2 | glutaredoxin 2 | -0.0072101 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00721003 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00720597 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00720481 |
| PDGFC | platelet derived growth factor C | -0.00720146 |
| OLFML2B | olfactomedin-like 2B | -0.00719927 |
| MMP2 | matrix metallopeptidase 2 | -0.00719566 |
| SDC4 | syndecan 4 | -0.00717716 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00716649 |
| PRDX2 | peroxiredoxin 2 | -0.00714547 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0071358 |
| PCP4 | Purkinje cell protein 4 | -0.00713373 |
| ACVR1 | activin A receptor, type I | -0.00712855 |
| OLA1 | Obg-like ATPase 1 | -0.00712564 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00711251 |
| SOD3 | superoxide dismutase 3, extracellular | -0.00710957 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.00710143 |
| HMOX1 | heme oxygenase 1 | -0.00709138 |
| MICU2 | mitochondrial calcium uptake 2 | -0.00706356 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00704881 |
| LY96 | lymphocyte antigen 96 | -0.0070393 |
| SLN | sarcolipin | -0.0070296 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -0.00702325 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.00702075 |
| KLK5 | kallikrein-related peptidase 5 | -0.00700433 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00699692 |
| IL1R1 | interleukin 1 receptor, type I | -0.00697934 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00697691 |
| RNF167 | ring finger protein 167 | -0.00693357 |
| FRZB | frizzled-related protein | -0.00689927 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00689686 |
| TNNT3 | troponin T type 3 (skeletal, fast) | -0.0068794 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00686283 |
| C9ORF16 | chromosome 9 open reading frame 16 | -0.00686162 |
| TRIM8 | tripartite motif containing 8 | -0.00685562 |
| KRT14 | keratin 14, type I | -0.00684287 |
| WBP1L | WW domain binding protein 1-like | -0.00684079 |
| CHN1 | chimerin 1 | -0.00680429 |
| RANBP1 | RAN binding protein 1 | -0.00679888 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00678653 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00677927 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00677418 |
| TES | testin LIM domain protein | -0.00677378 |
| GPR137B | G protein-coupled receptor 137B | -0.0067603 |
| CST3 | cystatin C | -0.0067567 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00674836 |
| ORC4 | origin recognition complex, subunit 4 | -0.00672253 |
| MYBPC1 | myosin binding protein C, slow type | -0.00671838 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.00671056 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00670358 |
| CKM | creatine kinase, muscle | -0.00670172 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00668731 |
| LYPLA2 | lysophospholipase II | -0.00668051 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00666858 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00666806 |
| APOA1 | apolipoprotein A-I | -0.00666667 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00665788 |
| EPHA4 | EPH receptor A4 | -0.00661707 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.00661462 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.0065774 |
| CYBRD1 | cytochrome b reductase 1 | -0.00657104 |
| TNNC2 | troponin C type 2 (fast) | -0.00655858 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | -0.00654763 |
| CHPF | chondroitin polymerizing factor | -0.00653686 |
| SSH3 | slingshot protein phosphatase 3 | -0.0065368 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00652463 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00652244 |
| TMEM176B | transmembrane protein 176B | -0.00652023 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | -0.00651964 |
| LIMA1 | LIM domain and actin binding 1 | -0.00650123 |
| MT3 | metallothionein 3 | -0.00650004 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00648305 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00647487 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0064697 |
| LMNA | lamin A/C | -0.00646282 |
| S100A4 | S100 calcium binding protein A4 | -0.00646072 |
| CNTN1 | contactin 1 | -0.00644907 |
| IRF9 | interferon regulatory factor 9 | -0.0064368 |
| FLNC | filamin C, gamma | -0.00641919 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00641777 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.00640674 |
| HOPX | HOP homeobox | -0.0063969 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00639133 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00638939 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00638816 |
| VWA1 | von Willebrand factor A domain containing 1 | -0.00638419 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00637575 |
| TMEM223 | transmembrane protein 223 | -0.00636892 |
| TSPO | translocator protein (18kDa) | -0.00636639 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.006364 |
| BGN | biglycan | -0.0063522 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00634373 |
| MAGEA3 | melanoma antigen family A3 | -0.00633995 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | -0.00631904 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00631791 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00631684 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00631216 |
| GATA2 | GATA binding protein 2 | -0.00630715 |
| FBLN2 | fibulin 2 | -0.00629792 |
| ABHD14A | abhydrolase domain containing 14A | -0.00629238 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 | -0.00628884 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00627072 |
| RAB38 | RAB38, member RAS oncogene family | -0.00626257 |
| ORM1 | orosomucoid 1 | -0.00626025 |
| SGCE | sarcoglycan, epsilon | -0.00625579 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00624664 |
| PDGFD | platelet derived growth factor D | -0.00621293 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00621178 |
| TP63 | tumor protein p63 | -0.00620726 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00620543 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | -0.00619617 |
