ZDHHC8 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description zinc finger, DHHC-type containing 8|This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 29801)
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Genes

340 genes differentially expressed following the ZDHHC8 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
KLRC2 killer cell lectin-like receptor subfamily C, member 2 3.31269
HORMAD1 HORMA domain containing 1 3.31269
UNC13C unc-13 homolog C (C. elegans) 3.31269
NRAP nebulin-related anchoring protein 3.31269
GJB1 gap junction protein, beta 1, 32kDa 3.31269
LRRC55 leucine rich repeat containing 55 3.31269
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 3.31269
FETUB fetuin B 3.31269
OLIG2 oligodendrocyte lineage transcription factor 2 3.31269
OLFM4 olfactomedin 4 3.31269
MUSK muscle, skeletal, receptor tyrosine kinase 3.31269
SSTR1 somatostatin receptor 1 3.31269
PCDHB9 protocadherin beta 9 3.31269
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 3.31269
MYBPHL myosin binding protein H-like 3.31269
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 3.31269
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 3.31269
TXLNB taxilin beta 3.31269
GPR52 G protein-coupled receptor 52 3.31269
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.31269
IL22RA1 interleukin 22 receptor, alpha 1 3.31269
CD209 CD209 molecule 3.31269
NXPH3 neurexophilin 3 3.31269
FABP2 fatty acid binding protein 2, intestinal 3.31269
MFAP4 microfibrillar-associated protein 4 3.31269
ATOH7 atonal homolog 7 (Drosophila) 3.31269
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 3.31269
TSHZ1 teashirt zinc finger homeobox 1 3.31269
THSD1 thrombospondin, type I, domain containing 1 3.31269
MYL7 myosin, light chain 7, regulatory 3.31269
FAM181B family with sequence similarity 181, member B 3.31269
SPAG8 sperm associated antigen 8 3.31269
BOLA2 bolA family member 2 3.31269
FGF7 fibroblast growth factor 7 3.31269
SCIN scinderin 3.31269
IL2RA interleukin 2 receptor, alpha 3.31269
CRYGN crystallin, gamma N 3.31269
SLC23A3 solute carrier family 23, member 3 3.31269
TCAF2 TRPM8 channel-associated factor 2 3.31269
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 3.31269
TDRD6 tudor domain containing 6 3.31269
C9ORF152 chromosome 9 open reading frame 152 3.31269
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 3.31269
CRH corticotropin releasing hormone 3.31269
TTLL2 tubulin tyrosine ligase-like family member 2 3.31269
MEIKIN meiotic kinetochore factor 3.31269
MUC22 mucin 22 3.31269
METTL21C methyltransferase like 21C 3.31269
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 3.31269
TEX53 testis expressed 53 3.31269
PPP4R3B protein phosphatase 4 regulatory subunit 3B 3.31269
H1-6 H1.6 linker histone, cluster member 3.31269
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 3.31269
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 3.31269
PTH1R parathyroid hormone 1 receptor 3.31269
ZNF726 zinc finger protein 726 3.31269
GPX5 glutathione peroxidase 5 3.31269
TAS2R60 taste receptor, type 2, member 60 3.31269
BDKRB1 bradykinin receptor B1 3.31269
MIOX myo-inositol oxygenase 3.31269
PLAAT4 phospholipase A and acyltransferase 4 3.31269
CCN5 cellular communication network factor 5 3.31269
SMIM42 small integral membrane protein 42 3.31269
WASH8P WAS protein family homolog 8, pseudogene 3.31269
ANKRD42-DT ANKRD42 divergent transcript 3.31269
REELD1 reeler domain containing 1 3.31269
H3C13 H3 clustered histone 13 3.31269
PEAK3 PEAK family member 3 3.31269
H2AC1 H2A clustered histone 1 3.31269
GSTT4 glutathione S-transferase theta 4 3.31269
CFAP206 cilia and flagella associated protein 206 3.31269
DNAAF8 dynein axonemal assembly factor 8 3.31269
FOXC2 forkhead box C2 3.31269
TSPAN1 tetraspanin 1 3.31269
MEOX1 mesenchyme homeobox 1 3.31269
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 3.31269
CLDN2 claudin 2 3.31269
PRB4 proline-rich protein BstNI subfamily 4 3.31269
IL12RB1 interleukin 12 receptor, beta 1 3.31269
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 3.31269
FPR1 formyl peptide receptor 1 3.31269
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.31269
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 3.31269
PLVAP plasmalemma vesicle associated protein 3.31269
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.31269
TLR4 toll-like receptor 4 3.31269
CCDC42 coiled-coil domain containing 42 3.31269
CNTN6 contactin 6 3.31269
LTF lactotransferrin 3.31269
GPR84 G protein-coupled receptor 84 3.31269
GPR132 G protein-coupled receptor 132 3.31269
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 3.31269
SAMD11 sterile alpha motif domain containing 11 3.31269
RRBP1 ribosome binding protein 1 3.31269
MIA melanoma inhibitory activity 3.31269
GDF10 growth differentiation factor 10 3.31269
FOLR1 folate receptor 1 (adult) 3.31269
PRSS51 protease, serine, 51 3.31269
BTNL3 butyrophilin-like 3 3.31269
C9ORF64 chromosome 9 open reading frame 64 3.31269
MAP3K19 mitogen-activated protein kinase kinase kinase 19 3.31269
TBC1D10C TBC1 domain family, member 10C 3.31269
PRM1 protamine 1 3.31269
PLET1 placenta expressed transcript 1 3.31269
FAM177B family with sequence similarity 177, member B 3.31269
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 3.31269
MUCL1 mucin-like 1 3.31269
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 3.31269
TTLL10 tubulin tyrosine ligase-like family member 10 3.31269
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 3.31269
HSPB2 heat shock 27kDa protein 2 3.31269
HSF4 heat shock transcription factor 4 3.31269
KRT13 keratin 13, type I 3.31269
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 3.31269
PMP2 peripheral myelin protein 2 3.31269
VAX2 ventral anterior homeobox 2 3.31269
A3GALT2 alpha 1,3-galactosyltransferase 2 3.31269
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 3.31269
CCDC152 coiled-coil domain containing 152 3.31269
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 3.31269
VWA7 von Willebrand factor A domain containing 7 3.31269
RGS4 regulator of G-protein signaling 4 3.31269
LY6G6D lymphocyte antigen 6 complex, locus G6D 3.31269
NKX6-1 NK6 homeobox 1 3.31269
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 3.31269
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.31269
FKBP1C FK506 binding protein 1C 3.31269
FOXS1 forkhead box S1 3.31269
GSDMC gasdermin C 3.31269
GSDMA gasdermin A 3.31269
RGS8 regulator of G-protein signaling 8 3.31269
SLC38A8 solute carrier family 38, member 8 3.31269
DAW1 dynein assembly factor with WDR repeat domains 1 3.31269
SEC14L3 SEC14-like 3 (S. cerevisiae) 3.31269
HELT helt bHLH transcription factor 3.31269
PCDH19 protocadherin 19 3.31269
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 3.31269
KLK11 kallikrein-related peptidase 11 3.31269
UTS2B urotensin 2B 3.31269
ITGB7 integrin, beta 7 3.31269
TF transferrin 3.31269
DLX1 distal-less homeobox 1 3.31269
RRH retinal pigment epithelium-derived rhodopsin homolog 3.31269
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.31269
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 3.31269
CDCP2 CUB domain containing protein 2 3.31269
ANGPTL3 angiopoietin-like 3 3.31269
ANGPTL7 angiopoietin-like 7 3.31269
TGM6 transglutaminase 6 3.31269
SPNS3 spinster homolog 3 (Drosophila) 3.31269
CLCA1 chloride channel accessory 1 3.31269
NPAS4 neuronal PAS domain protein 4 3.31269
CLCNKA chloride channel, voltage-sensitive Ka 3.31269
SYTL4 synaptotagmin-like 4 3.31269
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 3.31269
SLC7A4 solute carrier family 7, member 4 3.31269
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 3.31269
IRX4 iroquois homeobox 4 3.31269
NRSN1 neurensin 1 3.31269
WDFY4 WDFY family member 4 3.31269
GRM2 glutamate receptor, metabotropic 2 3.31269
ACSM4 acyl-CoA synthetase medium-chain family member 4 3.31269
GPBAR1 G protein-coupled bile acid receptor 1 3.31269
LMO7 LIM domain 7 3.28723
ARMCX6 armadillo repeat containing, X-linked 6 3.1127
RSAD2 radical S-adenosyl methionine domain containing 2 3.1127
NKTR natural killer cell triggering receptor 3.06472
TLCD3B TLC domain containing 3B 3.04848
MARVELD3 MARVEL domain containing 3 2.98609
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 2.87742
DAGLA diacylglycerol lipase, alpha 2.8664
SP140L SP140 nuclear body protein-like 2.8664
INSYN2B inhibitory synaptic factor family member 2B 2.8664
GPANK1 G patch domain and ankyrin repeats 1 2.83631
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 2.76066
MAGEE1 melanoma antigen family E1 2.74911
SLC30A6 solute carrier family 30 (zinc transporter), member 6 2.72475
SYN3 synapsin III 2.70069
IFT27 intraflagellar transport 27 2.67554
PLAA phospholipase A2-activating protein 2.61731
CCAR1 cell division cycle and apoptosis regulator 1 2.57138
ST7L suppression of tumorigenicity 7 like 2.56602
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.55664
CHODL chondrolectin 2.52257
OCRL oculocerebrorenal syndrome of Lowe 2.50847
TMEM45B transmembrane protein 45B 2.49562
MPL MPL proto-oncogene, thrombopoietin receptor 2.46882
BABAM1 BRISC and BRCA1 A complex member 1 2.45222
TMEM88 transmembrane protein 88 2.37924
ECE2 endothelin converting enzyme 2 2.37924
SLC49A3 solute carrier family 49 member 3 2.37924
DES desmin 2.37924
FOXP2 forkhead box P2 2.37924
DNAH12 dynein, axonemal, heavy chain 12 2.37924
BCL6B B-cell CLL/lymphoma 6, member B 2.37924
ASB14 ankyrin repeat and SOCS box containing 14 2.37924
FMN2 formin 2 2.37363
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 2.35152
ARHGAP1 Rho GTPase activating protein 1 2.34374
MYH10 myosin, heavy chain 10, non-muscle 2.34374
TMEM170A transmembrane protein 170A 2.31845
RAB4B RAB4B, member RAS oncogene family 2.30109
UBIAD1 UbiA prenyltransferase domain containing 1 2.27389
TMCO4 transmembrane and coiled-coil domains 4 2.27389
AIRIM AFG2 interacting ribosome maturation factor 2.26037
DGKI diacylglycerol kinase, iota 2.25642
B3GAT2 beta-1,3-glucuronyltransferase 2 2.23928
MACIR macrophage immunometabolism regulator 2.23636
ZFP64 ZFP64 zinc finger protein 2.19147
COMMD5 COMM domain containing 5 2.19075
OXTR oxytocin receptor 2.17903
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2.16045
ZDHHC23 zinc finger, DHHC-type containing 23 2.14817
EPS15 epidermal growth factor receptor pathway substrate 15 2.13294
TMEM106B transmembrane protein 106B 2.12648
DPYD dihydropyrimidine dehydrogenase 2.12648
MBD1 methyl-CpG binding domain protein 1 2.12648
CUL5 cullin 5 2.12611
ATP5MC1 ATP synthase membrane subunit c locus 1 2.12561
HAUS1 HAUS augmin-like complex, subunit 1 2.12435
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.10563
STAC3 SH3 and cysteine rich domain 3 2.10563
MPV17L2 MPV17 mitochondrial membrane protein-like 2 2.06768
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.06733
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1 2.05423
MEGF6 multiple EGF-like-domains 6 2.04617
KBTBD6 kelch repeat and BTB (POZ) domain containing 6 2.04527
LCOR ligand dependent nuclear receptor corepressor 2.04099
DLEU7 deleted in lymphocytic leukemia, 7 2.04039
SSBP4 single stranded DNA binding protein 4 2.04007
MYO1C myosin IC 2.0338
ZNF181 zinc finger protein 181 2.0338
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 2.0338
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 2.0338
PNPO pyridoxamine 5'-phosphate oxidase 2.02896
PMM1 phosphomannomutase 1 2.02896
METTL18 methyltransferase like 18 2.02514
EFL1 elongation factor like GTPase 1 2.02514
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 2.02247
TAPT1 transmembrane anterior posterior transformation 1 2.00235

decreased expression

Symbol Name Standardized Value
SMOC1 SPARC related modular calcium binding 1 -3.31269
HACL2 2-hydroxyacyl-CoA lyase 2 -3.31269
PCDHA1 protocadherin alpha 1 -3.31269
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K -3.31269
KRABD3 KRAB domain containing 3 -3.31269
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -3.31269
ZFP69 ZFP69 zinc finger protein -3.16416
KLHL31 kelch-like family member 31 -3.1127
LOXL4 lysyl oxidase-like 4 -3.1127
C2CD2L C2CD2-like -3.1127
C17ORF78 chromosome 17 open reading frame 78 -3.1127
CBLN3 cerebellin 3 precursor -3.1127
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 -3.1127
SPINK1 serine peptidase inhibitor, Kazal type 1 -3.1127
RAI2 retinoic acid induced 2 -3.1127
VCX variable charge, X-linked -3.1127
TMC8 transmembrane channel-like 8 -3.1127
SPX spexin hormone -3.1127
MYO7A myosin VIIA -3.1127
GPR22 G protein-coupled receptor 22 -3.1127
GJA5 gap junction protein, alpha 5, 40kDa -3.1127
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -3.1127
PCDHGA11 protocadherin gamma subfamily A, 11 -3.1127
NPNT nephronectin -3.1127
SCIMP SLP adaptor and CSK interacting membrane protein -3.1127
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -3.1127
TNS1-AS1 TNS1 antisense RNA 1 -3.1127
C17ORF114 chromosome 17 open reading frame 114 -3.1127
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 -3.1127
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -3.1127
VEGFD vascular endothelial growth factor D -3.1127
LRRIQ3 leucine-rich repeats and IQ motif containing 3 -3.1127
ZNF534 zinc finger protein 534 -3.1127
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -3.1127
OR56A3 olfactory receptor, family 56, subfamily A, member 3 -3.1127
PLB1 phospholipase B1 -3.1127
ITPKA inositol-trisphosphate 3-kinase A -3.1127
POU2F3 POU class 2 homeobox 3 -3.1127
SYNM synemin, intermediate filament protein -2.95434
RBP2 retinol binding protein 2, cellular -2.89137
ADAM28 ADAM metallopeptidase domain 28 -2.88798
ETAA1 Ewing tumor-associated antigen 1 -2.86392
ZYG11B zyg-11 family member B, cell cycle regulator -2.76588
CATSPERQ catsper channel auxiliary subunit theta -2.75898
RIMS2 regulating synaptic membrane exocytosis 2 -2.6719
RBM38 RNA binding motif protein 38 -2.62037
MRPL36 mitochondrial ribosomal protein L36 -2.61743
MAP2 microtubule-associated protein 2 -2.59818
CAPRIN1 cell cycle associated protein 1 -2.57558
SNX1 sorting nexin 1 -2.57138
CARD10 caspase recruitment domain family, member 10 -2.51003
ZNF274 zinc finger protein 274 -2.50876
DCPH1 damage control phosphatase 1 -2.47489
SGO2 shugoshin 2 -2.43716
FASTKD3 FAST kinase domains 3 -2.424
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.42151
ELL3 elongation factor RNA polymerase II-like 3 -2.42151
SCN2A sodium channel, voltage gated, type II alpha subunit -2.42151
SYT16 synaptotagmin XVI -2.40925
MTNR1A melatonin receptor 1A -2.40888
RUSF1 RUS family member 1 -2.39008
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -2.37363
PPP4R2 protein phosphatase 4, regulatory subunit 2 -2.35152
MYSM1 Myb-like, SWIRM and MPN domains 1 -2.34827
DCBLD1 discoidin, CUB and LCCL domain containing 1 -2.33295
PARP9 poly (ADP-ribose) polymerase family, member 9 -2.32062
RARB retinoic acid receptor, beta -2.32062
PGRMC1 progesterone receptor membrane component 1 -2.31229
FAAP20 FA core complex associated protein 20 -2.27965
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.27832
PROKR2 prokineticin receptor 2 -2.27389
ZNF582 zinc finger protein 582 -2.27389
PGBD4 piggyBac transposable element derived 4 -2.27389
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -2.27389
CCR10 chemokine (C-C motif) receptor 10 -2.27389
PPP1R9A protein phosphatase 1, regulatory subunit 9A -2.27319
SCAND1 SCAN domain containing 1 -2.26488
CSTB cystatin B (stefin B) -2.26037
FRMD8 FERM domain containing 8 -2.25642
FA2H fatty acid 2-hydroxylase -2.22648
CCDC167 coiled-coil domain containing 167 -2.22315
GPR107 G protein-coupled receptor 107 -2.22315
RWDD4 RWD domain containing 4 -2.21934
UBL7 ubiquitin-like 7 -2.19075
CFAP221 cilia and flagella associated protein 221 -2.18941
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -2.18941
TICAM2 toll-like receptor adaptor molecule 2 -2.13294
FBXO17 F-box protein 17 -2.12467
NT5E 5'-nucleotidase, ecto (CD73) -2.11081
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -2.11081
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -2.10592
MYO9A myosin IXA -2.10479
SERF2 small EDRK-rich factor 2 -2.08692
C1QTNF4 C1q and tumor necrosis factor related protein 4 -2.06546
COL5A3 collagen, type V, alpha 3 -2.0338
EGLN2 egl-9 family hypoxia-inducible factor 2 -2.0185
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 -2.00934
EHD4 EH-domain containing 4 -2.00235
NEXN nexilin (F actin binding protein) -2.00235
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 -2.00235