ZDHHC9 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description zinc finger, DHHC-type containing 9|This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 51114)
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Genes

360 genes differentially expressed following the ZDHHC9 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CHCT1 CHD1 helical C-terminal domain containing 1 2.81792
FZD1 frizzled class receptor 1 2.81792
DAW1 dynein assembly factor with WDR repeat domains 1 2.81792
LIPH lipase, member H 2.81792
PENK proenkephalin 2.81792
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.81792
ZPLD1 zona pellucida-like domain containing 1 2.81792
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.81792
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 2.81792
LRRC56 leucine rich repeat containing 56 2.81792
VSTM2L V-set and transmembrane domain containing 2 like 2.81792
NPIPB11 nuclear pore complex interacting protein family, member B11 2.81792
RELN reelin 2.81792
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.81792
PRDM16 PR domain containing 16 2.81792
SPTBN5 spectrin, beta, non-erythrocytic 5 2.81792
HBG2 hemoglobin, gamma G 2.81792
EXOC3L1 exocyst complex component 3-like 1 2.81792
TDRD1 tudor domain containing 1 2.81792
HHEX hematopoietically expressed homeobox 2.81792
ZNF787 zinc finger protein 787 2.81792
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.81792
GLOD5 glyoxalase domain containing 5 2.81792
LCN1 lipocalin 1 2.81792
ORM2 orosomucoid 2 2.81792
PRRT4 proline-rich transmembrane protein 4 2.81792
ADGRE3 adhesion G protein-coupled receptor E3 2.75209
CDKL3 cyclin-dependent kinase-like 3 2.75209
OR2A25 olfactory receptor, family 2, subfamily A, member 25 2.75209
KNG1 kininogen 1 2.75209
RPS18 ribosomal protein S18 2.75209
ASCL5 achaete-scute family bHLH transcription factor 5 2.75209
HBA2 hemoglobin, alpha 2 2.75209
SYCP2 synaptonemal complex protein 2 2.75209
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.75209
CFHR3 complement factor H-related 3 2.75209
LAPTM5 lysosomal protein transmembrane 5 2.75209
ZBTB6 zinc finger and BTB domain containing 6 2.75209
AGTR1 angiotensin II receptor, type 1 2.75209
TMEM176B transmembrane protein 176B 2.75209
PAX3 paired box 3 2.75209
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 2.75209
HCRTR2 hypocretin (orexin) receptor 2 2.75209
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.75209
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.75209
NCF1 neutrophil cytosolic factor 1 2.75209
MEIKIN meiotic kinetochore factor 2.75209
AFMID arylformamidase 2.75209
RFX6 regulatory factor X, 6 2.75209
CRYGB crystallin, gamma B 2.75209
TBATA thymus, brain and testes associated 2.75209
SPINT3 serine peptidase inhibitor, Kunitz type, 3 2.75209
GPR26 G protein-coupled receptor 26 2.75209
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.75209
TRIM10 tripartite motif containing 10 2.75209
PON1 paraoxonase 1 2.75209
PNMA5 paraneoplastic Ma antigen family member 5 2.75209
AMTN amelotin 2.75209
OSR2 odd-skipped related transciption factor 2 2.75209
CORT cortistatin 2.75209
XCL2 chemokine (C motif) ligand 2 2.75209
ASB12 ankyrin repeat and SOCS box containing 12 2.75209
NEU4 sialidase 4 2.75209
PRDM12 PR domain containing 12 2.75209
TBL1X transducin (beta)-like 1X-linked 2.75209
SPMIP11 sperm microtubule inner protein 11 2.75209
MT4 metallothionein 4 2.75209
PROP1 PROP paired-like homeobox 1 2.75209
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 2.75209
CAPN9 calpain 9 2.75209
RHCG Rh family, C glycoprotein 2.75209
SRGN serglycin 2.75209
SPRR2A small proline-rich protein 2A 2.75209
PGF placental growth factor 2.75209
ADRB3 adrenoceptor beta 3 2.75209
PHF24 PHD finger protein 24 2.75209
ZFTA zinc finger translocation associated 2.75209
CABCOCO1 ciliary associated calcium binding coiled-coil 1 2.75209
CIMAP1D CIMAP1 family member D 2.75209
H2BK1 H2B.K variant histone 1 2.75209
H4C12 H4 clustered histone 12 2.75209
TMEM238L transmembrane protein 238 like 2.75209
SMIM43 small integral membrane protein 43 2.75209
HOATZ HOATZ cilia and flagella associated protein 2.75209
ACP4 acid phosphatase 4 2.75209
SLC49A3 solute carrier family 49 member 3 2.75209
RTL5 retrotransposon Gag like 5 2.75209
RPS6 ribosomal protein S6 2.75209
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 2.75209
FOXI2 forkhead box I2 2.75209
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33 2.75209
SLURP2 secreted LY6/PLAUR domain containing 2 2.75209
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 2.75209
MYH13 myosin, heavy chain 13, skeletal muscle 2.75209
GDF10 growth differentiation factor 10 2.75209
C1ORF162 chromosome 1 open reading frame 162 2.75209
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.75209
UROC1 urocanate hydratase 1 2.75209
RGS21 regulator of G-protein signaling 21 2.75209
PLB1 phospholipase B1 2.75209
TAS1R2 taste receptor, type 1, member 2 2.75209
TMEM40 transmembrane protein 40 2.75209
ASB9 ankyrin repeat and SOCS box containing 9 2.75209
MIOX myo-inositol oxygenase 2.75209
GC group-specific component (vitamin D binding protein) 2.75209
OR52E4 olfactory receptor, family 52, subfamily E, member 4 2.75209
IMPG2 interphotoreceptor matrix proteoglycan 2 2.75209
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.75209
LTF lactotransferrin 2.75209
ZNF683 zinc finger protein 683 2.75209
SCN10A sodium channel, voltage gated, type X alpha subunit 2.75209
CXCR5 chemokine (C-X-C motif) receptor 5 2.75209
PCDHGB1 protocadherin gamma subfamily B, 1 2.75209
SMIM22 small integral membrane protein 22 2.75209
ITGB7 integrin, beta 7 2.75209
CA5A carbonic anhydrase VA, mitochondrial 2.75209
OR5B3 olfactory receptor, family 5, subfamily B, member 3 2.75209
SLC38A8 solute carrier family 38, member 8 2.75209
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.75209
LRRC25 leucine rich repeat containing 25 2.75209
NUTM2F NUT family member 2F 2.75209
POTEF POTE ankyrin domain family, member F 2.75209
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.75209
FGF16 fibroblast growth factor 16 2.75209
APOL6 apolipoprotein L, 6 2.75209
RHAG Rh-associated glycoprotein 2.75209
KCNK9 potassium channel, two pore domain subfamily K, member 9 2.75209
ZNF132 zinc finger protein 132 2.75209
OCM oncomodulin 2.75209
GOLGA6A golgin A6 family, member A 2.75209
AQP7 aquaporin 7 2.75209
BTNL3 butyrophilin-like 3 2.75209
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.75209
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.75209
CPA2 carboxypeptidase A2 (pancreatic) 2.75209
EDN1 endothelin 1 2.75209
KLF2 Kruppel-like factor 2 2.75209
TBXA2R thromboxane A2 receptor 2.75209
WNT7B wingless-type MMTV integration site family, member 7B 2.75209
CLIC1 chloride intracellular channel 1 2.75209
SSC5D scavenger receptor cysteine rich family, 5 domains 2.75209
SIRPG signal-regulatory protein gamma 2.75209
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.75209
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.75209
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.75209
GAS2L2 growth arrest-specific 2 like 2 2.75209
THSD1 thrombospondin, type I, domain containing 1 2.75209
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.75209
IL23R interleukin 23 receptor 2.75209
C2ORF78 chromosome 2 open reading frame 78 2.75209
ZC2HC1B zinc finger, C2HC-type containing 1B 2.75209
PODN podocan 2.75209
ERVV-1 endogenous retrovirus group V, member 1 2.75209
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.75209
GOLGA8K golgin A8 family, member K 2.75209
MB myoglobin 2.75209
SPAG6 sperm associated antigen 6 2.75209
BHLHA15 basic helix-loop-helix family, member a15 2.75209
SPAG8 sperm associated antigen 8 2.75209
NFE2 nuclear factor, erythroid 2 2.75209
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 2.75209
TRPM5 transient receptor potential cation channel, subfamily M, member 5 2.75209
RTN4RL1 reticulon 4 receptor-like 1 2.75209
MGP matrix Gla protein 2.75209
LGALS2 lectin, galactoside-binding, soluble, 2 2.75209
ZNF835 zinc finger protein 835 2.75209
RPL18A ribosomal protein L18a 2.75209
TMEM45B transmembrane protein 45B 2.75209
THEM5 thioesterase superfamily member 5 2.75209
MYO1G myosin IG 2.75209
NENF neudesin neurotrophic factor 2.75209
SHISA3 shisa family member 3 2.75209
LPO lactoperoxidase 2.75209
EMCN endomucin 2.75209
BTBD6 BTB (POZ) domain containing 6 2.74523
HPS5 Hermansky-Pudlak syndrome 5 2.73801
ATL3 atlastin GTPase 3 2.73801
DORIP1 dopamine receptor interacting protein 1 2.69143
FOXL2NB FOXL2 neighbor 2.64155
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.63639
COPRS coordinator of PRMT5, differentiation stimulator 2.61611
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.57632
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 2.50627
TLE4 transducin-like enhancer of split 4 2.50627
CD79B CD79b molecule, immunoglobulin-associated beta 2.44983
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.44208
KLHDC2 kelch domain containing 2 2.42881
KNTC1 kinetochore associated 1 2.42437
ACTG2 actin, gamma 2, smooth muscle, enteric 2.42303
CACYBP calcyclin binding protein 2.38416
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.37255
SMYD3 SET and MYND domain containing 3 2.36986
ISG20 interferon stimulated exonuclease gene 20kDa 2.3562
UBXN1 UBX domain protein 1 2.35357
GSDMA gasdermin A 2.35172
TMEM26 transmembrane protein 26 2.35172
HCRT hypocretin (orexin) neuropeptide precursor 2.35172
BOP1 block of proliferation 1 2.34833
GTPBP8 GTP-binding protein 8 (putative) 2.34752
SAXO6 stabilizer of axonemal microtubules 6 2.34731
RNF170 ring finger protein 170 2.34731
SERINC3 serine incorporator 3 2.32941
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough 2.32941
TCEA2 transcription elongation factor A (SII), 2 2.32582
COL9A2 collagen, type IX, alpha 2 2.31429
BTBD16 BTB (POZ) domain containing 16 2.31429
ARHGAP27 Rho GTPase activating protein 27 2.25961
NOSIP nitric oxide synthase interacting protein 2.25633
FHIP1A FHF complex subunit HOOK interacting protein 1A 2.24433
CELF2 CUGBP, Elav-like family member 2 2.23297
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 2.20406
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.19642
HEPH hephaestin 2.19352
SYNPR synaptoporin 2.19195
CLIC4 chloride intracellular channel 4 2.1891
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.18613
TIFA TRAF-interacting protein with forkhead-associated domain 2.16751
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.16706
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.16067
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 2.14787
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.14072
GIN1 gypsy retrotransposon integrase 1 2.10459
VRK1 vaccinia related kinase 1 2.10459
NT5DC2 5'-nucleotidase domain containing 2 2.09669
MOB2 MOB kinase activator 2 2.09307
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.09198
LCOR ligand dependent nuclear receptor corepressor 2.07913
WDR76 WD repeat domain 76 2.07913
MRTFA myocardin related transcription factor A 2.07913
KMT2D lysine (K)-specific methyltransferase 2D 2.07901
RPAP1 RNA polymerase II associated protein 1 2.06758
LRRC8D leucine rich repeat containing 8 family, member D 2.06722
REXO2 RNA exonuclease 2 2.0639
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.0514
SRP54 signal recognition particle 54kDa 2.0514
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 2.04537
FBXW10B F-box and WD repeat domain containing 10B 2.03657
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 2.02572
SLC25A42 solute carrier family 25, member 42 2.02515
TRIM26 tripartite motif containing 26 2.02515
SETD9 SET domain containing 9 2.0202
COL9A1 collagen, type IX, alpha 1 2.0153
ATRX alpha thalassemia/mental retardation syndrome X-linked 2.01417
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.00889
INO80B INO80 complex subunit B 2.0088
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 2.00534
CD9 CD9 molecule 2.00011

decreased expression

Symbol Name Standardized Value
DNAH6 dynein, axonemal, heavy chain 6 -2.81792
GRM1 glutamate receptor, metabotropic 1 -2.81792
PROKR1 prokineticin receptor 1 -2.81792
SLITRK3 SLIT and NTRK-like family, member 3 -2.81792
ZNF879 zinc finger protein 879 -2.81792
GHRL ghrelin/obestatin prepropeptide -2.75209
DNALI1 dynein, axonemal, light intermediate chain 1 -2.75209
CA9 carbonic anhydrase IX -2.75209
TACC3 transforming, acidic coiled-coil containing protein 3 -2.75209
DPPA3 developmental pluripotency associated 3 -2.75209
CCDC38 coiled-coil domain containing 38 -2.75209
NPIPA5 nuclear pore complex interacting protein family, member A5 -2.75209
C12ORF42 chromosome 12 open reading frame 42 -2.75209
ZNF804B zinc finger protein 804B -2.75209
SNAI2 snail family zinc finger 2 -2.75209
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 -2.75209
ZFP57 ZFP57 zinc finger protein -2.75209
MUC1 mucin 1, cell surface associated -2.75209
CSP2 CS pseudogene 2 -2.75209
LOC124903233 uncharacterized LOC124903233 -2.75209
DOP1A DOP1 leucine zipper like protein A -2.75209
TFF3 trefoil factor 3 (intestinal) -2.75209
GCSAM germinal center-associated, signaling and motility -2.75209
CCND1 cyclin D1 -2.75209
RBMS3 RNA binding motif, single stranded interacting protein 3 -2.75209
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 -2.75209
IL12RB1 interleukin 12 receptor, beta 1 -2.75209
HRH1 histamine receptor H1 -2.75209
CFL1 cofilin 1 (non-muscle) -2.75209
AGTRAP angiotensin II receptor-associated protein -2.75209
AKAP14 A kinase (PRKA) anchor protein 14 -2.75209
ZC3H11C zinc finger CCCH-type containing 11C -2.75209
TRAF3IP3 TRAF3 interacting protein 3 -2.75209
VAV1 vav 1 guanine nucleotide exchange factor -2.75209
KLHDC8A kelch domain containing 8A -2.75209
PCNP PEST proteolytic signal containing nuclear protein -2.75209
UPK1A uroplakin 1A -2.75209
WBP2NL WBP2 N-terminal like -2.75209
ITLN2 intelectin 2 -2.75209
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -2.75209
FGF18 fibroblast growth factor 18 -2.75209
ZNF114 zinc finger protein 114 -2.74032
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -2.72889
GLIPR1L1 GLI pathogenesis-related 1 like 1 -2.68492
NR1D1 nuclear receptor subfamily 1, group D, member 1 -2.64155
SGMS2 sphingomyelin synthase 2 -2.64155
VSTM2B V-set and transmembrane domain containing 2B -2.64155
ADGRF3 adhesion G protein-coupled receptor F3 -2.64155
RNF135 ring finger protein 135 -2.63817
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -2.63384
FGF14 fibroblast growth factor 14 -2.60179
DIABLO diablo, IAP-binding mitochondrial protein -2.60179
DRC10 dynein regulatory complex subunit 10 -2.52244
CTTN cortactin -2.50622
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 -2.38809
TOX2 TOX high mobility group box family member 2 -2.38302
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -2.37621
FRMPD2 FERM and PDZ domain containing 2 -2.36902
C4ORF50 chromosome 4 open reading frame 50 -2.36902
OR6A2 olfactory receptor, family 6, subfamily A, member 2 -2.36902
CDK12 cyclin-dependent kinase 12 -2.35172
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.31429
FRMD3 FERM domain containing 3 -2.31429
MEF2C myocyte enhancer factor 2C -2.2897
PLCE1 phospholipase C, epsilon 1 -2.25495
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -2.24621
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -2.23967
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.23297
RECQL4 RecQ protein-like 4 -2.23191
KDM6B lysine (K)-specific demethylase 6B -2.21157
ATG4C autophagy related 4C, cysteine peptidase -2.19195
GHRHR growth hormone releasing hormone receptor -2.18973
UCMA upper zone of growth plate and cartilage matrix associated -2.18973
FLT3LG fms-related tyrosine kinase 3 ligand -2.18973
SEC24D SEC24 family member D -2.1891
DCX doublecortin -2.18613
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) -2.16854
CCDC112 coiled-coil domain containing 112 -2.16706
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.16706
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.16706
DRC4 dynein regulatory complex subunit 4 -2.16706
TXNDC15 thioredoxin domain containing 15 -2.16706
C8ORF82 chromosome 8 open reading frame 82 -2.16706
DCP2 decapping mRNA 2 -2.16706
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 -2.16706
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -2.16421
PLP1 proteolipid protein 1 -2.15224
ADD2 adducin 2 (beta) -2.14731
GGT7 gamma-glutamyltransferase 7 -2.14533
EBF1 early B-cell factor 1 -2.14131
HSBP1L1 heat shock factor binding protein 1-like 1 -2.14072
CCDC117 coiled-coil domain containing 117 -2.12427
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.1081
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -2.10459
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -2.0898
SRSF8 serine/arginine-rich splicing factor 8 -2.08958
MRPS18A mitochondrial ribosomal protein S18A -2.08624
SLC61A1 solute carrier family 61 member 1 -2.07031
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -2.05816
LRRC75A leucine rich repeat containing 75A -2.04966
RFTN1 raftlin, lipid raft linker 1 -2.04097
PNPLA3 patatin-like phospholipase domain containing 3 -2.03657
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -2.03657
ACADVL acyl-CoA dehydrogenase, very long chain -2.03031
RAB6A RAB6A, member RAS oncogene family -2.02515
DYNLT3 dynein, light chain, Tctex-type 3 -2.02515
WDR74 WD repeat domain 74 -2.02515
MDC1 mediator of DNA-damage checkpoint 1 -2.0202
ZNF574 zinc finger protein 574 -2.01639
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -2.01417
MTCH2 mitochondrial carrier 2 -2.00011
STAT5B signal transducer and activator of transcription 5B -2.00011
TMEM108 transmembrane protein 108 -2.00011