ZFX Gene Set

Dataset JASPAR Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description zinc finger protein, X-linked|This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 7543)
External Link http://www.ncbi.nlm.nih.gov/gene/7543
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Genes

31 target genes of the ZFX transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

Symbol Name
APRT adenine phosphoribosyltransferase
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C14ORF180 chromosome 14 open reading frame 180
C2ORF81 chromosome 2 open reading frame 81
CABLES2 Cdk5 and Abl enzyme substrate 2
CCL28 chemokine (C-C motif) ligand 28
CLDN14 claudin 14
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CRYBA4 crystallin, beta A4
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DIO3OS DIO3 opposite strand/antisense RNA (head to head)
DMWD dystrophia myotonica, WD repeat containing
GADD45A growth arrest and DNA-damage-inducible, alpha
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
INIP INTS3 and NABP interacting protein
MDK midkine (neurite growth-promoting factor 2)
OVCA2 ovarian tumor suppressor candidate 2
PBX4 pre-B-cell leukemia homeobox 4
PDGFB platelet-derived growth factor beta polypeptide
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1R18 protein phosphatase 1, regulatory subunit 18
PRSS35 protease, serine, 35
RDH16 retinol dehydrogenase 16 (all-trans)
RPIA ribose 5-phosphate isomerase A
SEPP1 selenoprotein P, plasma, 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
THY1 Thy-1 cell surface antigen
VAMP7 vesicle-associated membrane protein 7
XCR1 chemokine (C motif) receptor 1