ZM-447439 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

29 kinases inhibited by the ZM-447439 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
RET ret proto-oncogene 1.35325
LCK LCK proto-oncogene, Src family tyrosine kinase 1.35325
AURKB aurora kinase B 1.35325
BLK BLK proto-oncogene, Src family tyrosine kinase 1.32726
EGFR epidermal growth factor receptor 1.3104
ERBB4 erb-b2 receptor tyrosine kinase 4 1.3104
PTK6 protein tyrosine kinase 6 1.30212
SLK STE20-like kinase 1.28583
ERBB3 erb-b2 receptor tyrosine kinase 3 1.28583
AXL AXL receptor tyrosine kinase 1.22432
HCK HCK proto-oncogene, Src family tyrosine kinase 1.20983
EPHB6 EPH receptor B6 1.20983
MERTK MER proto-oncogene, tyrosine kinase 1.18186
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 1.18186
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.16177
RIPK2 receptor-interacting serine-threonine kinase 2 1.15523
MST1R macrophage stimulating 1 receptor 1.08845
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.0718
HIPK4 homeodomain interacting protein kinase 4 1.03535
TNK2 tyrosine kinase, non-receptor, 2 0.988726
LTK leukocyte receptor tyrosine kinase 0.971727
CDK7 cyclin-dependent kinase 7 0.963557
LYN LYN proto-oncogene, Src family tyrosine kinase 0.936602
ULK3 unc-51 like kinase 3 0.93295
BTK Bruton agammaglobulinemia tyrosine kinase 0.93295
CSK c-src tyrosine kinase 0.91201
MET MET proto-oncogene, receptor tyrosine kinase 0.895762
AURKA aurora kinase A 0.889549
FLT3 fms-related tyrosine kinase 3 0.883492