ZNF384 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description zinc finger protein 384|This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011] (NCBI Entrez Gene Database, 171017)
External Link http://www.ncbi.nlm.nih.gov/gene/171017
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Genes

19 interacting proteins for ZNF384 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
EIF5A2 eukaryotic translation initiation factor 5A2
HOXC9 homeobox C9
KCTD17 potassium channel tetramerization domain containing 17
MPP1 membrane protein, palmitoylated 1, 55kDa
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
OPTN optineurin
PCBP1 poly(rC) binding protein 1
SOX2 SRY (sex determining region Y)-box 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBK1 TANK-binding kinase 1
UBC ubiquitin C
VIM vimentin
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZYX zyxin