ZP2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description zona pellucida glycoprotein 2 (sperm receptor)|The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 7783)
External Link http://www.ncbi.nlm.nih.gov/gene/7783
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4 interacting proteins for ZP2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACR acrosin
PLCG1 phospholipase C, gamma 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ZPBP zona pellucida binding protein