Zellweger Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A peroxisomal disease that is characterized by the reduction or absence of functional peroxisomes in the cells of an individual that has_material_basis_in autosomal recessive inheritance of a mutation in the peroxisome biogenesis factor (PEX) genes. (Human Disease Ontology, DOID_905)
External Link https://www.disgenet.org/browser/0/1/0/C0043459
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Genes

36 genes associated with the disease Zellweger Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACOX2 acyl-CoA oxidase 2, branched chain
AGPS alkylglycerone phosphate synthase
BCAP31 B-cell receptor-associated protein 31
CAT catalase
CHRM3 cholinergic receptor, muscarinic 3
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
ETFA electron-transfer-flavoprotein, alpha polypeptide
FAM206A family with sequence similarity 206, member A
GNPAT glyceronephosphate O-acyltransferase
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
LPA lipoprotein, Lp(a)
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PEX1 peroxisomal biogenesis factor 1
PEX10 peroxisomal biogenesis factor 10
PEX11A peroxisomal biogenesis factor 11 alpha
PEX11B peroxisomal biogenesis factor 11 beta
PEX12 peroxisomal biogenesis factor 12
PEX13 peroxisomal biogenesis factor 13
PEX14 peroxisomal biogenesis factor 14
PEX16 peroxisomal biogenesis factor 16
PEX19 peroxisomal biogenesis factor 19
PEX2 peroxisomal biogenesis factor 2
PEX26 peroxisomal biogenesis factor 26
PEX3 peroxisomal biogenesis factor 3
PEX5 peroxisomal biogenesis factor 5
PEX6 peroxisomal biogenesis factor 6
PEX7 peroxisomal biogenesis factor 7
PHEX phosphate regulating endopeptidase homolog, X-linked
TSPO translocator protein (18kDa)